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121. Sacsr9Wnkmwkqw V9Kpdd (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/_saCsr9WNkmwKqW_V9kPDd
     April 01, 2014 - Two trials found no effect on cardiovascu- lar disease incidence or mortality. … Only the WHI trial reported cardiovascular disease incidence and mortality and all-cause mortality, and … One trial in women reported a lower cardiovascular disease mortality in the intervention group, but mortality … rates for myocardial infarction and stroke did not differ statistically. … Overall, there was no significant effect on incidence of all types of cancer or on cancer mortality rates

122. Draft Research Plan: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/aspirin-use-to-prevent-cardiovascular-disease-and-colorectal-cancer-preventive-medication
     January 30, 2020 - patients without known cardiovascular disease (CVD) reduce CVD and colorectal cancer (CRC) incidence and mortality … , or all-cause mortality? … What is the effect of aspirin discontinuation on CVD, CRC, all-cause mortality, and bleeding outcomes … Category Included Excluded Aim Primary prevention of CVD, CRC, and/or all-cause mortality … KQ 1: Myocardial infarction, stroke, death from myocardial infarction or stroke, CRC incidence, CRC mortality

123. Draft Research Plan: Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/aspirin-use-to-prevent-cardiovascular-disease-preventive-medication
     January 30, 2020 - patients without known cardiovascular disease (CVD) reduce CVD and colorectal cancer (CRC) incidence and mortality … , or all-cause mortality? … What is the effect of aspirin discontinuation on CVD, CRC, all-cause mortality, and bleeding outcomes … Category Included Excluded Aim Primary prevention of CVD, CRC, and/or all-cause mortality … KQ 1: Myocardial infarction, stroke, death from myocardial infarction or stroke, CRC incidence, CRC mortality

124. Archived: Brief Evidence Summary: Bladder Cancer in Adults: Screening, 2004 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/brief-evidence-summary/bladder-cancer-screening-2004
     June 07, 2004 - men. 3 Men are 2.5 times more likely to be diagnosed with bladder cancer than women; age-adjusted mortality … rates from bladder cancer are similarly higher for men than for women. … Key Question 1: Is there direct evidence that screening for bladder cancer reduces morbidity or mortality … home screening with a chemical reagent strip to effect earlier detection and reduce bladder cancer mortality … Since these cancers may or may not progress to clinically significant morbidity or mortality, such direct

125. Draft Research Plan: Prostate Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/prostate-cancer-screening-adults
     October 12, 2023 - screening for prostate cancer vs. no screening or usual care on short- or long-term prostate cancer mortality … , incidence of metastatic prostate cancer, all-cause mortality, quality of life, and function?     … , incidence of metastatic prostate cancer, all-cause mortality, quality of life, and function?     … Mortality results from a randomized prostate-cancer screening trial. … Screening and prostate-cancer mortality in a randomized European study.

126. Draft Research Plan: Helicobacter Pylori Infection: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/heliobacter-pylori-infection-screening
     November 17, 2022 - children or adults improve patient health outcomes (e.g., health-related quality of life, morbidity and mortality … from gastric adenocarcinoma or other upper gastrointestinal cancers, all-cause mortality, peptic ulcer … from gastric adenocarcinoma or other upper gastrointestinal cancers, all-cause mortality, peptic ulcer … Other upper gastrointestinal cancers (e.g., MALT lymphoma; esophageal cancer) morbidity, mortality. … All-cause mortality. Health-related quality of life. Gastritis; peptic ulcer disease.

127. Screening for Bladder Cancer: A Brief Evidence Update (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/NZcLsqV-5K7hyfot-qHQp9
     November 01, 2004 - black men.3 Men are 2.5 times more likely to be diagnosed with bladder cancer than women; age-adjusted mortality … rates from bladder cancer are similarly higher for men than for women. … Is there direct evidence that screening for bladder cancer reduces morbidity or mortality? … home screening with a chemical reagent strip to effect earlier detection and reduce bladder cancer mortality … Does treatment of early-stage bladder cancer reduce morbidity and mortality from this disease?

128. Draft Research Plan: Skin Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/skin-cancer-screening-1
     January 07, 2021 - skin cancer screening with visual skin examination by clinicians in reducing skin cancer morbidity and mortality … or all-cause mortality? … the association between detection of skin cancer at a precancerous or early stage and morbidity and mortality … due to skin cancer or all-cause mortality? … ; all-cause mortality KQ 2: Stage or lesion thickness at detection of skin cancer or precancerous

129. Draft Research Plan: Hypertensive Disorders of Pregnancy: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/hypertensive-disorders-pregnancy-screening
     May 20, 2021 - used to identify hypertensive disorders of pregnancy for reducing maternal and perinatal morbidity and mortality … How does racism and social inequalities contribute to existing inequities in morbidity and mortality … For example, what accounts for higher mortality from hypertensive disorders of pregnancy among Black … Are there effective interventions that could redress existing inequities in morbidity and mortality from … intravascular coagulation Longer-term health consequences from complications of pregnancy Maternal mortality

130. Archived: Evidence Summary: Prostate Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary43/prostate-cancer-screening-2012
     October 07, 2011 - ; RR, 0.52 [CI, 0.37 to 0.73] for all-cause mortality). … It did not report prostate cancer–specific mortality. … rate of 0.5% in Medicare claimants 60 ; 3 other large observational studies reported similar findings … CI, 0.59–2.5) 5-y mortality: 21/158 (13%) vs. 147/378 (39%); HR, 0.71 (CI, 0.4–1.4) 10-y mortality … Mortality results from a randomized prostate-cancer screening trial.

131. Archived: Colorectal Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-june-2016
     June 15, 2016 - Black adults have the highest incidence and mortality rates compared with other racial/ethnic subgroups … rate more than flexible sigmoidoscopy alone. 14 Modeling studies conducted by CISNET also consistently … rate. 15 Colonoscopy has both indirect and direct harms. … Black and Alaska Native individuals have a higher incidence of and mortality rate from colorectal cancer … rate than the flexible sigmoidoscopy–only group (hazard ratio [HR], 0.62 [95% CI, 0.42 to 0.90] vs 0.84

132. Screening for Ovarian Cancer: An Updated Evidence Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/Home/GetFile/1/16768/ovarian-cancer-final-evid-review/pdf
     February 01, 2018 - rate of 7.4 per 100,000 women. … rates (7 per 100,000), slightly lower than the mortality rates observed among non-Hispanic white women … of the rarity of ovarian cancer, and because the mortality rates from ovarian cancer are quite high … Overall, in the PLCO, the ovarian cancer mortality rate was greater in the intervention arm compared … rate IG: 2.7 per 10,000 p-y CG: 3.2 per 10,000 p-y IG: 2.8 per 10,000 p-y CG: 3.2 per 10,000 p

133. Evidence Summary: Ovarian Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/ovarian-cancer-screening
     February 13, 2018 - Main Outcomes and Measures: Ovarian cancer mortality, false-positive screening results and surgery, … No trial found a significant difference in ovarian cancer mortality with screening. … Based on data from 2010-2014, the estimated annual incidence rate was 11.4 per 100,000 and the mortality … rate was 7.4 per 100,000, with a projected 14,080 deaths from ovarian cancer in 2017. 1 , 2 More than … United States Cancer Statistics (USCS): 1999-2014 cancer incidence and mortality data.

134. Final Research Plan: Pancreatic Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/pancreatic-cancer-screening
     August 17, 2017 - or all-cause mortality (KQ1); whether screening effectiveness varies by clinically relevant subpopulations … , all-cause mortality, or quality of life (KQ4); and the harms of treatment of screen-detected pancreatic … or all-cause mortality? … Does treatment of screen-detected or asymptomatic pancreatic adenocarcinoma improve cancer mortality, … all-cause mortality, or quality of life?

135. Final Research Plan: Hypertensive Disorders of Pregnancy: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hypertensive-disorders-pregnancy-screening
     September 02, 2021 - used to identify hypertensive disorders of pregnancy for reducing maternal and perinatal morbidity and mortality … How do racism and social inequalities contribute to existing inequities in morbidity and mortality from … For example, what accounts for higher mortality from hypertensive disorders of pregnancy among Black … Are there effective interventions that could redress existing inequities in morbidity and mortality from … intravascular coagulation Longer-term health consequences from complications of pregnancy Maternal mortality

136. Procedure Manual Section 4. Evidence Review Development | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-section-4-evidence-review-development
     March 30, 2025 - When a condition is a common cause of mortality, all-cause mortality is the desirable health outcome … However, few preventive interventions have a measurable effect on all-cause mortality. … may not decline, even when cause-specific mortality is reduced. … though the intervention reduces cause-specific mortality. … over reasonable time frames for a study because the force of mortality is so large at this age.

137. Draft Research Plan: Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/aspirin-use-to-prevent-preeclampsia-and-related-morbidity-and-mortality-preventive-medication1
     June 20, 2019 - progress Draft Research Plan Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality … syndrome Disseminated intravascular coagulation Mental health diagnoses or symptoms Maternal mortality … restriction/small for gestational age (<10th percentile weight for gestational age) Stillbirth or neonatal mortality

138. Final Recommendation Statement: Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
     September 28, 2021 - Final Recommendation Statement Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality … Worldwide, preeclampsia is the second most common cause of maternal morbidity and mortality. … approximately 4% of pregnancies in the US and contributes to both maternal and infant morbidity and mortality … There was also a reduction in perinatal mortality (pooled RR, 0.79 [95% CI, 0.66-0.96]; 11 studies; … Low-dose aspirin use for the prevention of morbidity and mortality from preeclampsia: U.S.

139. Recommendation: Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
     September 28, 2021 - Final Recommendation Statement Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality … It is strengthened by new evidence from additional trials demonstrating reduced risks of perinatal mortality … Worldwide, preeclampsia is the second most common cause of maternal morbidity and mortality. … There was also a reduction in perinatal mortality (pooled RR, 0.79 [95% CI, 0.66-0.96]; 11 studies; … Low-dose aspirin use for the prevention of morbidity and mortality from preeclampsia: U.S.

140. Final Research Plan: Prostate Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prostate-cancer-screening-adults
     December 21, 2023 - , incidence of metastatic prostate cancer, all-cause mortality, quality of life, and function?     … , incidence of metastatic prostate cancer, all-cause mortality, quality of life, and function?     … ; all-cause mortality; prostate cancer–specific morbidity (i.e., bone pain from metastases and urinary … Mortality results from a randomized prostate-cancer screening trial. … Screening and prostate-cancer mortality in a randomized European study.