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441. EHC Protocol: Making Healthcare Safer IV: Deprescribing to Reduce Medication Harms in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/deprescribing-protocol.pdf
     July 01, 2023 - common for numerous physical and mental health conditions and can have benefits on morbidity and mortality … outcome measures (e.g., utilization, falls, adverse drug events, adverse drug withdrawal events, mortality

442. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Telehealth (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ehc-research-gaps-telehealth.pdf
     April 01, 2023 - o Remote intensive-care unit consultations likely reduce mortality. … o Telehealth consultations in emergency services likely reduce heart attack mortality.

443. Evidence Map on Home and Community Based Services (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-map-hcbs-protocol.pdf
     July 27, 2023 - Potential outcome measures include quality of life, functional independence, general satisfaction of care, mortality … long-term care) without HCBS • No HCBS while living in the home or community • None Outcomes • Mortality

444. Antibiotics-Respiratory-Infection Clinician (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
     March 01, 2016 - activity or missed work and rates of continuing symptoms, hospitalization, treatment failure, or mortality … in hospitalizations or combined adverse effects/lack of efficacy outcome 1 RCT — No difference in mortality

445. Ch 6-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
     October 30, 2012 - focus on clinical outcomes, such as recurrence-free survival from cancer or coronary heart disease mortality … Some clinical outcomes, such as all-cause mortality, can be ascertained directly and may be more reliable … blocker, was superior to placebo in reduction of onset of new coronary lesions; on the other hand, mortality … In these studies, mortality is also assigned a dollar value, although techniques for assigning value … the costs of treatments and benefits of treatments in terms of a specified outcome, such as reduced mortality

446. Ace-Inhibitor-Arb-Update-Surveillance-160328 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
     May 29, 2025 - $$ Click$here$to$enter$text.$ $ $ Mortality$and$Major$Cardiovascular$Events$$ $ SRC(Literature … $DRIs$with$any$certainty$for$these$critical$outcomes.$ •$ 21$studies$reported$mortality,$MI,$or$clinical … Metabolic$syndrome,$a$cluster$of$risk$factors$that$increase$the$risk$of$cardiovascular$morbidity$and$mortality … ARB$irbesartan$and$ found$greater$reductions$in$mean$ sitting$BP$with$aliskiren$(P$=$ 0.019).$$ Mortality … $DRIs$with$any$ certainty$for$these$critical$outcomes.$ •$ 21$studies$reported$mortality,$ MI,$or

447. March 2nd Mitigating Racial Bias in Healthcare Algorithms Public Meeting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-2.pdf
     May 15, 2023 - LAPS2 SOFA, OASIS, APACHE IVa SOFA tiering systems Compared models/tierin g systems N In-hospital mortality … LAPS2 SOFA, OASIS, APACHE IVa SOFA tiering systems Compared models/tierin g systems N In-hospital mortality … SOFA, OASIS, APACHE IVa SOFA tiering systems Compared models/tierin g systems N In-hospital mortality … re Rich, Expansive Study Finds https://www.nytimes.com/interactive/2023/02/12/upshot/child-maternal-mortality-rich-poor.html

448. PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
     April 01, 2013 - improved decisionmaking about biopsy), and long-term health outcomes (clinical utility), including mortality … improved decisionmaking about biopsy), and long-term health outcomes (clinical utility), including mortality … improved decisionmaking about biopsy), and long-term health outcomes (clinical utility), including mortality … Long- term outcomes, including morbidity, mortality and quality of life followed over 10 to 20 years … In addition, no studies were identified that addressed long-term outcomes (e.g., mortality, morbidity

449. CER 205 Disposition of Comments for Physiologic Predictors of Severe Injury: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-205-predictors-trauma-care-disposition-comments.pdf
     April 01, 2018 - It does not directly asses the relationship with mortality and so I am not sure how the sensitivity … includes death, operative intervention and blood transfusion) as compared to studies which only address mortality … of this section as well as reference to the included study that evaluated it ability to predict mortality

450. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - been a proven treatment for reversing opioid overdose, used for more than 40 years, opioid overdose mortality … rates continue to rise. … intervention addresses a significant unmet need and might be able to reduce opioid overdose–related mortality

451. The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
     September 19, 2014 - designed to assess risk of overdose, addiction, abuse, or misuse Overdose (as indicated by all-cause mortality … quality comparative study of methadone versus another opioid (long-acting morphine) found decreased mortality … Opioid dose and drug-related mortality in patients with nonmalignant pain. … Bending the prescription opioid dosing and mortality curves: impact of the Washington State opioid … Comparative mortality among Department of Veterans Affairs patients prescribed methadone or long-acting

452. Dietary-Supplements Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
     January 01, 2013 - Clinical cardiovascular effectiveness/ efficacy outcomes (e.g., mortality and specific cardiovascular … report does not need updating Ginkgo biloba With no deaths observed, insufficient evidence for mortality … In three short-term efficacy trials of omega-3 fatty acid and statin coadministration, effects on mortality … Clinical cardiovascular effectiveness/ efficacy outcomes (e.g., mortality and specific cardiovascular … New Evidence: Ginkgo biloba With no deaths observed, insufficient evidence for mortality

453. Disposition of Comments: Comparative Effectiveness Review No. 273_Treatment of Stages I-III Squamous Cell Anal Cancer: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-273-anal-cancer-disposition-comments.pdf
     August 20, 2024 - Disease - specific mortality may reflect better the impact of therapies for localized SCCA on pts survival

454. Ch 5-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
     January 01, 2012 - Paradoxical relations of drug treatment with mortality in older persons. Epidemiology. … Surgeon volume and operative mortality in the United States. N Engl J Med. … The empirical relation between surgical volume and mortality. N Engl J Med. … Hospital volume and surgical mortality in the United States. N Engl J Med.

455. Renal Artery Stenosis Management Strategies: An Updated Comparative Effectiveness Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_executive.pdf
     August 01, 2016 - The assessed outcomes included all-cause and cardiovascular mortality, cardiovascular events (including … no statistically significant differences or, overall, minimal clinically important differences in mortality … One RCT that compared PTRAS and surgery found no statistically significant difference in mortality, … nonrandomized studies of PTRAS versus medical therapy found no statistically significant difference in mortality … Studies of PTRAS versus surgery found no statistically significant difference in mortality or BP control

456. Misuse of Prescription Stimulants in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol-amendment.pdf
     November 26, 2024 - prescription No prior or current stimulant misuse Comparators N/A N/A Outcomes Morbidity and mortality

457. Methods-Guidance-Topics Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topics_methods.pdf
     January 01, 2010 - health-related topic selection Criterion Definition Disease burden Extent of disability, morbidity, or mortality … of illness (quality-of-life years lost). 2 A condition associated with significant morbidity or mortality … conclusions from prior assessments. 1 Potential impact Potential to improve health outcomes (morbidity, mortality … quality of life (for patients or caregivers), reduce avoidable morbidity, reduce avoidable premature mortality … Outcome: Health outcomes: morbidity, mortality, quality of life. Timing Duration of followup.

458. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/data-extraction.ppt
     January 01, 2009 - Overall Mortality […] 24 deaths occurred in the PCI group, […] and 25 in the MT group […] MED and MT … MT = medical treatment PCI = percutaneous coronary intervention Overall Mortality Figure Outcome PCI … (205) MT (203) Dead 24 25 28 35 Overall Mortality Figure Look at the number of survivors

459. Prehospital EMS Blood Transfusion and Fluid Interventions for Hemorrhagic Shock (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
     February 04, 2025 - Background and Objectives for the Systematic Review The leading cause of preventable mortality in both … 1.5 million per year globally, and is second only to central nervous system injury as the cause of mortality … PICOTS Inclusion Criteria Exclusion Criteria Outcomes Patient Health Outcomes (highest priority) • Mortality … Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic

460. Making Healthcare Safer IV: Supply Chain Disruption Monitoring Programs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
     January 01, 2024 - Increased morbidity and mortality is also associated with supply chain disruptions.11 Perhaps the … supply chain disruptions No comparator Outcome • Patient safety measures/patient harms (e.g., mortality