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401. Acs-Pci-Adjunctive-Devices Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
     July 01, 2010 - ST-segment resolution, MBG, TIMI-3 flow, ejection fraction and distal embolization) and terminal outcomes (mortality … Prolonged Procedure Time (KQ 1 & 3) (KQ 2) (KQ 1 & 3) Final health outcomes  Mortality … morbidity (ST segment resolution, MBG, TIMI-3 blood flow, ejection fraction, distal embolization, MACE), mortality

402. Making Healthcare Safer IV: Summary of Findings on Patient Safety Practices and Ratings by a Technical Expert Panel, 2024-2025 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-patient-safety-practices-year-2.pdf
     May 01, 2025 - moderately improved hospital length of stay but had inconsistent results and did not significantly impact mortality … PMS with intermittent vital sign input inconsistently affected mortality. 1b. … length of hospital stay and modifying monitored parameters was associated with decreased hospital mortality … review confirms the moderate evidence suggesting continuous monitoring's benefit in reducing hospital mortality … • Evidence Summary o Mandated nurse ratios generally improved patient and staff outcomes (lower mortality

403. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-adherence-interventions_research-protocol.pdf
     August 18, 2011 - increase their risk of death. 8 Despite the established capacity for many medications to reduce both mortality … deaths, at least 10 percent of hospital admissions, 11 and substantial worsening of morbidity and mortality … adherence Medication adherence Outcomes Biomarkers of clinical outcomes Clinical outcomes - Mortality … changes in intermediate outcomes, such as biomarkers, or in other health outcomes, such as morbidity and mortality … e.g., screening, diet, exercise, lifestyle changes) Outcomes Medication adherence Biomarkers, mortality

404. EHC Research Protocol: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
     January 01, 2019 - malignant and premalignant colon tumors found by colonoscopy, and what is the incidence of colon cancer mortality … to complicated diverticulitis  Diverticulitis-related morbidities (e.g., abscess formation) and mortality … episode of complicated diverticulitis  Diverticulitis-related morbidities (e.g., strictures) and mortality … o Diverticulitis-related morbidities o Mortality, both diverticulitis-related and all-cause • Medium … cancer • Colonic premalignant lesions (e.g., hyperplastic polyps and adenomas) • Colorectal cancer mortality

405. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
     January 30, 2012 - immediately life-threatening as ventricular arrhythmias, AF is associated with significant morbidity and mortality … embolic stroke, heart failure, and cognitive impairment; reduced quality of life; and higher overall mortality … Even more importantly, warfarin therapy was associated with a 26 percent reduction in all-cause mortality … stratified by type and location) o Occurrence of other clinical outcomes:  Myocardial infarction  Mortality … stratified by type and location) • Occurrence of other clinical outcomes: o Myocardial infarction o Mortality

406. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
     April 01, 2022 - original report in finding higher doses of opioids associated with increased risk of overdose and mortality … case-control study (2,311 cases) found higher dose of opioids associated with increased risk of mortality … Mixed mechanism vs. opioid agonist and mortality, falls/fracture, hospitalization for adverse event … Mortality After Discontinuation of Primary Care-Based Chronic Opioid Therapy for Pain: a Retrospective … Reduction in mortality risk with opioid agonist therapy: a systematic review and meta-analysis.

407. Breastfeeding and Health Outcomes for Infants and Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol.pdf
     February 01, 2023 - thickness, atherosclerosis o Metabolic syndrome o Incidence and prevalence of CVD o CVD-related mortality … caries o Malocclusions • Sudden infant death syndrome / sudden unexpected infant death • Infant mortality

408. Evidence-based Practice Center Systematic Review Protocol - Management of Infantile Epilepsies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-disposition-comments.pdf
     October 25, 2022 - development included seizure freedom, seizure frequency, seizure severity, Engel classification, all cause mortality … include risks of untreated refractory epilepsy which is 1/100 years for SUDEP alone so the cumulative mortality … Regarding the mortality after surgery, our protocol specified inclusion of any mortality, so we describe … the mortality as reported by study authors. … development included seizure freedom, seizure frequency, seizure severity, Engel classification, all cause mortality

409. Adverse Effects of First-Line Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
     February 07, 2018 - hypotension • Cognitive impairment/confusion • Suicide/suicide attempt • Suicidal thoughts • Seizures • Mortality … • Cognitive impairment /confusion • Suicide/suicide attempt • Suicidal thoughts • Seizures • Mortality … The critical outcomes include suicide, mortality, hospitalization, serious adverse events, arrhythmias … Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity

410. depression-pregnancy-postpartum-protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
     March 29, 2013 - interactions and some measures of infant development; in extreme cases it may increase the risk of infant mortality … Harms Maternal • Death (including suicide, all-cause mortality and cause-specific [e.g., cardiac] … discontinuation of treatment • Serious adverse events reported Fetus, Infant, and Child • All-cause mortality … Complications/ or exp Pregnancy Outcome/ or exp Fetal Development/) and (exp Infant/ or exp Infant Mortality

411. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - Along these lines, the following report on mortality related to spinal stimulators and intrathecal … pumps should be included-it is a report from the manufacturer itself: Coffey et al, Mortality associated … The one year mortality from SCS was 1.35%. … This broader safety data, such as overall mortality from spinal cord stimulation, is therefore not

412. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - Along these lines, the following report on mortality related to spinal stimulators and intrathecal … pumps should be included-it is a report from the manufacturer itself: Coffey et al, Mortality associated … The one year mortality from SCS was 1.35%. … This broader safety data, such as overall mortality from spinal cord stimulation, is therefore not

413. Treatment Strategies for Women With Coronary Artery Disease: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
     February 01, 2013 - trials comparing PCI with CABG, two studies suggested a nonsignificant benefit of PCI in reducing mortality … Sex differences in mortality following acute coronary syndromes. … Sex differences in hospital mortality after coronary artery bypass surgery: evidence for a higher mortality … Sex differences in mortality following acute coronary syndromes. … Sex differences in hospital mortality after coronary artery bypass surgery: evidence for a higher mortality

414. Noninvasive Testing for Coronary Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
     January 15, 2015 - estimated $108.9 billion is spent annually on CAD treatment.4 Reduction in the prevalence, morbidity, and mortality … CAD is important for initiation of appropriate treatment and reduction of CAD-related morbidity and mortality … Important clinical outcomes include prevention of myocardial infarction (MI), premature mortality, … Chest pain in general practice: incidence, comorbidity and mortality. … Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic

415. Treatments for Acute Pain: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-protocol-acute-pain-treatments.pdf
     August 08, 2019 - Objectives for the Systematic Review Pain is nearly universal, contributing substantially to morbidity, mortality … Overdose Death Rates. 2019. … https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates. … lancet/PIIS0140-6736(19)30352-6.pdf https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates

416. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
     May 19, 2010 - will report outcome measures such as general health outcomes (e.g., SF-36), quality of life, and mortality … we will report outcome measures such as general health outcomes (e.g., SF36), quality of life, and mortality … Mortality Cardiovascular Myocardial infarction Arrhythmia - tachycardia Blood pressure increase

417. Standardized Library of Atrial Fibrillation Outcome Measures (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-library-afib.pdf
     November 15, 2018 - Fibrillation Outcome Measures OMF CATEGORY OUTCOME MEASURE DEFINITION REFERENCE Survival All-cause mortality … All-cause mortality Workgroup recommendation Survival Cardiovascular death Cardiovascular death … cardiac arrhythmia. 2004 ACC/AHA Key Data Elements (1) Survival Procedure-related death All-cause mortality

418. Breastfeeding and Health Outcomes for Infants and Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol-amendment.pdf
     February 03, 2025 - thickness, atherosclerosis o Metabolic syndrome o Incidence and prevalence of CVD o CVD-related mortality … caries o Malocclusions • Sudden infant death syndrome / sudden unexpected infant death • Infant mortality

419. Making Healthcare Safer IV_Rapid Review: Use of Structured Handoff Protocols for Intrahospital Within-Unit Transitions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/structured-handoff-rapid-research.pdf
     January 01, 2025 - that reported patient clinical outcomes, such as medical errors, adverse events, medication errors, mortality … The outcomes assessed were a heterogenous mixture of specific events like falls or patient mortality … rate Intervention: 10.9% Control: 11.7% Proportion of patients transferred to ICU Intervention … Association of intraoperative anaesthesia handovers with patient morbidity and mortality: a systematic … Association of intraoperative anaesthesia handovers with patient morbidity and mortality: a systematic

420. Medical Care for Adults with Down Syndrome (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol.pdf
     July 09, 2024 - around 60 years today.4, 14 However, significant disparities in access to care, quality of care, and mortality … rates exist between individuals with Down syndrome and those without, as well as among individuals … treatment Health and quality of life outcomes Harms: adverse events related to screening/diagnosis (mortality … values Healthcare utilization Final outcomes: Change in standardized symptom measures Morbidity/mortality … interventions Final Outcomes Change in standardized symptom measures Reduced morbidity Reduced mortality