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381. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-literacy_research-protocol.pdf
     January 22, 2010 -  Measures of disease incidence, prevalence, morbidity, and mortality. … includes such outcomes as stage of cancer presentation, arthritis disease severity, diabetes control, and death … rates. … Health literacy and mortality among elderly persons. Arch Intern Med 2007;167:1503-9. … Health literacy, cognitive abilities, and mortality among elderly persons.

382. Antipsychotics for the Prevention and Treatment of Delirium: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
     June 01, 2018 - prevalence >70% in critically ill patients ≥60 years.3, 4 Delirium is strongly associated with increased mortality … Use of rescue therapy  Use of physical restraint o Final health or patient-centered outcomes  Mortality … use of rescue therapy; use of physical restraint) o Final health or patient-centered outcomes (mortality … Does antipsychotic drug use increase the risk of long term mortality?

383. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
     July 01, 2009 - Major outcomes may include mortality, health-related quality of life, costs, potential harms, and for … For the outcome as a whole (e.g., mortality or quality of life), the table also gives the overall rating … It shows, for instance, that one fair-quality RCT reported mortality, which was lower by one patient … However, the evidence is insufficient to allow a conclusion for mortality. … Risk of bias: Consistency Directness Precision Absolute risk difference per 100 patients Mortality

384. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule_research-protocol.pdf
     March 14, 2012 - important to consider potential harms of testing such as capsule retention, radiation exposure, and mortality … It is important to consider potential harms such as capsule retention, radiation exposure, and mortality … services (hospitalizations, physician visits) Harms • Capsule retention • Radiation exposure • Mortality … hospitalizations and physician visits ○ Harms, such as capsule retention, radiation exposure, and mortality … at least one of the following outcomes: ○ Harms, such as capsule retention, radiation exposure, and mortality

385. Preterm-Birth-Terbutaline-Pump Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_surveillance.pdf
     January 30, 2013 - 3: increase the maternal harms of arrhythmia, heart failure, hyperglycemia, hypokalemia, maternal mortality … 95% CI:1.23, 526.6).13 Underpowered studies demonstrated indeterminate results for the outcomes of mortality … Thus, if the original review has found RR=0.70 for mortality, this implies RRR of 0.3. … If the updated meta-analytic result for mortality were 0.90, then the updated RRR would be 0.10, which … 95% CI:1.23, 526.6).13 Underpowered studies demonstrated indeterminate results for the outcomes of mortality

386. Preterm-Birth-Terbutaline-Pump Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_surveillance.pdf
     January 30, 2013 - 3: increase the maternal harms of arrhythmia, heart failure, hyperglycemia, hypokalemia, maternal mortality … 95% CI:1.23, 526.6).13 Underpowered studies demonstrated indeterminate results for the outcomes of mortality … Thus, if the original review has found RR=0.70 for mortality, this implies RRR of 0.3. … If the updated meta-analytic result for mortality were 0.90, then the updated RRR would be 0.10, which … 95% CI:1.23, 526.6).13 Underpowered studies demonstrated indeterminate results for the outcomes of mortality

387. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-3.pdf
     June 01, 2022 - Opioids vs. no opioids, long-term harms (all-cause mortality and cardiovascular events) Opioids … or cardiovascular mortality) • SOE: low, based on 1 (all- cause mortality) or 3 (cardiovascular … Mixed mechanism vs. opioid agonist and mortality, falls/fracture, hospitalization for adverse event … Reduction in mortality risk with opioid agonist therapy: a systematic review and meta-analysis. … Mortality Among People With Opioid Use Disorder: A Systematic Review and Meta-analysis.

388. Diabetes-Drugs-Utilization Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-drugs-utilization_research.pdf
     March 01, 2011 - dione, was found to be associated with myocardial infarction, major adverse cardiovascular events, mortality … from cardiovascular causes, and all-cause mortality.8 A more recent study comparing rosiglitazone … in claims occurred from 2007 to 2009, likely driven by highly publicized concerns about increased mortality

389. Colorectal-Surgery-Preparation Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_executive.pdf
     April 01, 2014 - 2010) found no benefit for OMBP in terms of anastomotic leakage, other surgical complications, or mortality … (N Events/N Patients Per Group) OR (95% CrI) Between-Study Variance (95% CrI) All-cause mortality … For outcomes reported by 10 or more studies (all-cause mortality, anastomotic leakage, and wound infection … Similarly, allocation concealment method was not associated with the effect sizes for all-cause mortality … bThese results pertain to the following outcomes: all-cause mortality, cause-specific mortality, anastomotic

390. Future Research Needs for Diagnosis of Obstructive Sleep Apnea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
     February 01, 2012 - OSA is an important public health issue, due to the considerable mortality and morbidity associated … Outcomes 4O: Other than all-cause mortality, clinical outcomes are understudied. … When assessing mortality outcomes, the timeframe could very well extend to decades. … Outcomes 4O: Other than all-cause mortality, clinical outcomes are understudied. … When assessing mortality outcomes, the timeframe could very well extend to decades.

391. medication-assisted-treatment-protocol-160224 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-use-disorder_research-protocol.pdf
     February 24, 2016 - due to heroin use.3 OUD is associated with decreased quality of life and increased morbidity and mortality … -­-­   Outcomes   Measures  of  use  or  access   Substance-­use-­related  outcomes,  including   mortality … Overdose Death Rates. … February 2015; http://www.drugabuse.gov/related-topics/trends- statistics/overdose-death-rates.

392. Appendicitis Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
     December 09, 2013 - diagnostic laparoscopy is generally considered safe, studies have reported variable rates of morbidity and mortality … Elderly and frail individuals with appendicitis have a higher complication rate and a higher risk of mortality … , maternal morbidity, maternal mortality) 7. … Mortality • Adverse effects of intervention(s) 1. … Infectious complications •  Diagnostic delay •  Length of hospital stay •  Fetal-maternal outcomes •  Mortality

393. worker-health-protocol-150526 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
     May 26, 2015 - They lead to mortality, morbidity, and considerable financial and social costs.1-3 At the same time, … chronic diseases such as smoking, physical inactivity, and poor diet are leading causes of morbidity and mortality … o KQ 2a: Health and safety outcomes: Mortality; incidence of injuries, cardiovascular disease or cancer … Estimates of costs, morbidity, and mortality. Arch Intern Med. 1997 Jul 28;157(14):1557-68.

394. Executive Summary_Systematic Review: Use of Telehealth During the COVID-19 Era (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/use-telehealth-during-COVID-19-executive-summary.pdf
     January 01, 2023 - the difference between telehealth and in-person care varied by the type of outcome; differences in mortality … rates and reported adverse events between telehealth and in-person care were small and/or not clinically

395. Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
     January 01, 2014 - evidence (drawn from 9 RCTs and 22 nonrandomized studies) that supports no significant difference in mortality … There is an evidence gap concerning long-term outcomes since neither RCT reported data on cardiac mortality … Outcomes of interest included therapeutic decisionmaking; patient-centered outcomes (e.g., mortality … Long-term health outcome and mortality evaluation after invasive coronary treatment using drug eluting … Impact of intravascular ultrasound guidance on long- term mortality in stenting for unprotected left

396. Evidence-based Practice Center Systematic Review Protocol: Depression in Children: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
     August 06, 2018 - other mental and physical health conditions, poor functional impairment, and increased risk of early mortality … Other important outcomes include a reduction in suicidality (thoughts, plans, or attempts), mortality … in final health outcomes (such as remission, response, relapse, depressive symptoms, suicidality, mortality … Dependency" OR TX “drug effects” OR DE "Drug Sensitivity" OR TX harm* OR TX "manic episode" OR TX mortality … Dependency" OR TX “drug effects” OR DE "Drug Sensitivity" OR TX harm* OR TX "manic episode" OR TX mortality

397. Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
     January 01, 2023 - breast cancer is the leading cause of global cancer incidence and remains a leading cause of cancer mortality … Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers

398. Topic 0549 Diagnosis and Management of Gout NSD _SJ Clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
     June 24, 2014 - Outcome(s): Health outcomes (e.g. mortality, morbidity, adverse events), functional status, patient

399. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
     July 01, 2014 - In extreme cases, postpartum depression may increase the risk of infant mortality through neglect, … For infant outcomes, we graded preterm birth, small for gestational age, neonatal mortality, congenital … Indirect evidence may be valuable for harms such as mortality and congenital anomalies, because signals … We had no direct evidence for the risk of infant mortality with maternal use of antidepressant drugs … A single cohort study reported no increased risk of neonatal mortality with SNRI or NRI use during

400. App-D-Opioid-Chronic-Pain-Surveillance-Report-3 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
     September 30, 2015 - ): 1.546 (1.082 to 2.210) vs. reference Adjusted HR (95% CI): 1.715 (1.082 to 2.718) vs. reference Mortality … provider availability, insurance coverage type, other medications, physical therapy status All-cause mortality … combination Overdose: ref vs. aOR 13.00 (95% CI 1.30 to 130.16) vs. aOR 6.27 (95% CI 1.91 to 20.55) All-cause mortality … . 20-50 vs. ≥50 Overdose: ref vs. aOR 2.39 (95% CI 0.89 to 6.46) vs. aOR 1.01 (95% CI 0.30 to 3.46) Mortality