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281. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
     June 01, 2010 - Preterm births contribute to more than 85% of all perinatal morbidity and mortality and are the leading … cause of infant mortality and long-term disability.1,2 In 2004, for example, more than 480,000 infants … as evidenced by a 20% increase in the proportion of preterm births since 1990.2 The morbidity and mortality … serious complications and for infants born preterm and at a low birthweight; and 3) reducing infant mortality … prematurity • Necrotizing enterocolitis • Neonatal sepsis • Patent ductus arteriosis • Neonatal mortality

282. Developing and Piloting a Tool To Create Dot Plots To Summarize Pooled Data for Multiple Outcomes in Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dot-plots-methods.pdf
     October 01, 2021 - outcomes; for the pilot we used pooled data for statins versus placebo or no statin and risk of all-cause mortality … , cardiovascular mortality, stroke (fatal or nonfatal), myocardial infarction (fatal or nonfatal), revascularization … Figure 1 Outcome No. of Trials trt_n trt_N ctrl_n ctrl_N RR cil ciu I- squared SOE All-cause Mortality … 15 1089 35967 1262 35164 0.86 0.80 0.93 0 High CV Mortality 10 343 32143 423 32179 0.82 0.71 0.94

283. Politi (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/politi.pdf
     May 29, 2025 - Surgery  for weight loss: efficacious in patients with BMI ≥40; unclear for BMI <40 • Peri-­‐operative mortality …  rates & adverse events might be worse in some settings.

284. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0456_07-27-2011.pdf
     January 01, 2011 - tube type), behavioral and other interventions Comparator(s): Standard oral feeding Outcome(s): Mortality

285. Developing and Piloting a Tool To Create Dot Plots To Summarize Pooled Data for Multiple Outcomes in Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/dot-plots-methods.pdf
     October 01, 2021 - outcomes; for the pilot we used pooled data for statins versus placebo or no statin and risk of all-cause mortality … , cardiovascular mortality, stroke (fatal or nonfatal), myocardial infarction (fatal or nonfatal), revascularization … Figure 1 Outcome No. of Trials trt_n trt_N ctrl_n ctrl_N RR cil ciu I- squared SOE All-cause Mortality … 15 1089 35967 1262 35164 0.86 0.80 0.93 0 High CV Mortality 10 343 32143 423 32179 0.82 0.71 0.94

286. Microsoft Word - Comp Eff 10.doc (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
     January 01, 2007 - Health outcomes—Mortality (all-cause mortality, cardiovascular disease-specific mortality, and cerebrovascular … Health outcomes: Mortality (all-cause mortality, cardiovascular disease-specific mortality, and cerebrovascular … Stable coronary artery disease: to reduce risk of cardiovascular mortality or nonfatal MI. … Post-MI: used to reduce cardiovascular mortality. … Mortality and major cardiovascular events?

287. Nephropathy-Contrast-Induced Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
     October 01, 2013 - for the outcomes of incidence of CIN, chronic kidney disease (CKD), end stage renal disease (ESRD), mortality … interventions to prevent contrast induced nephropathy, for the outcomes of incidence of CIN, CKD, ESRD, mortality … dialysis, hemofiltration, or kidney transplant) c) Other clinical outcomes ● Cardiac outcomes ● Mortality … dialysis, hemofiltration, or kidney transplant) c) Other clinical outcomes ● Cardiac outcomes ● Mortality … at 3 or 6 months ● Long-term clinical benefits of image quality ● Improved morbidity ● Improved mortality

288. Suppl-1-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/suppl-1-user-guide-to-ocer_130129.pdf
     January 01, 2011 - one reviews a seminal instrumental variable (IV) study in health care.7 In an examination of the mortality … McClellan’s RA estimates of ATT showed statistically significant reductions in mortality associated … with surgery for Medicare beneficiaries with AMI, whereas their IV LATE estimates showed no mortality … and were also unrelated to any remaining unmeasured factors related to both surgery choice and mortality … Does more intensive treatment of acute myocardial- infarction in the elderly reduce mortality?

289. high-cholesterol-medicines-update-protocol-130516 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/high-cholestorol-medicines-update_research-protocol.pdf
     December 31, 2013 - Multiple trials have evaluated the effects of cholesterol reduction on cardiovascular events and mortality … ,14 the incidence of a first major coronary event,15,16 and all-cause mortality.17 In patients with … , and all-cause mortality.18,19 There is ongoing debate about whether multiple agents should be used … Outcomes Clinical outcomes • All-cause mortality • Vascular death • Fatal MI, nonfatal MI, any or … Ten-­‐year mortality  from cardiovascular disease  in relation to cholesterol level among men with

290. Prostate-Cancer-Test Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_executive.pdf
     April 01, 2013 - using tPSA was to reduce the prevalence of advanced prostate cancer and prostate cancer-related mortality … through early detection, and improve quality of life.3,7,8 Prostate cancer mortality has decreased … improved decisionmaking about biopsy), and long- term health outcomes (clinical utility), including mortality … and (5) intermediate (diagnostic accuracy, impact on decisionmaking, harms) and long-term (e.g., mortality … Prostate-cancer mortality at 11 years of follow-up. N Engl J Med. 2012 Mar 15;366(11):981-90.

291. App-D-Opioid-Chronic-Pain-Surveillance-Report-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
     September 30, 2015 - ): 1.546 (1.082 to 2.210) vs. reference Adjusted HR (95% CI): 1.715 (1.082 to 2.718) vs. reference Mortality … provider availability, insurance coverage type, other medications, physical therapy status All-cause mortality … combination Overdose: ref vs. aOR 13.00 (95% CI 1.30 to 130.16) vs. aOR 6.27 (95% CI 1.91 to 20.55) All-cause mortality … . 20-50 vs. ≥50 Overdose: ref vs. aOR 2.39 (95% CI 0.89 to 6.46) vs. aOR 1.01 (95% CI 0.30 to 3.46) Mortality

292. Research White Paper - Assessing the Predictive Validity of Strength of Evidence Grades: A Meta-Epidemiological Study (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper.pdf
     September 01, 2015 - 1,381 RR: 1.08 (0.97 to 1.21) Buchleitner et al., 201212 Perioperative glycemic control and mortality … hospital stay 633 WMD: -0.18 (-0.39 to 0.04) Gafter et al., 201219 Antibiotic prophylaxis and mortality … 84,311 RR: 0.93 (0.87 to 0.98) Perez et al., 200942 Beta-blockers and mortality 71,457 RR: 0.96 … • For outcomes that can be considered extremely patient-relevant (e.g., mortality, stroke, myocardial … Effect of early treatment with anti-hypertensive drugs on short and long-term mortality in patients

293. Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel - Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
     November 01, 2017 - Key Question 4 No transfer to hospital Key Question 4 Health Outcomes • All Key Questions: Mortality … overdose with naloxone to a health care facility versus nontransport Outcomes • All Key Questions: Mortality … the strength of evidence for each Key Question and comparison for prioritized clinical outcomes (mortality … Expanded access to naloxone: options for critical response to the epidemic of opioid overdose mortality

294. Comparative Effectiveness Review No. 258_Diagnostic Errors in the Emergency Department: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diagnostic-error-executive-summary.pdf
     August 01, 2023 - Swiss study assessed deaths as an outcome among admitted patients and found a 2.3-fold increase in mortality … Estimated misdiagnosis-related mortality from the Canadian study (0.2%, PR 0.1 to 0.4) was bolstered … by similarity to the mortality estimate calculated from the two Western European studies (PR 0.2% to

295. Evidence Report No. 222, Data Linkage Strategies To Advance Youth Suicide Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research.pdf
     October 01, 2016 - Pharmacy benefit management organization, CDC’s national suicide mortality rates, U.S. … Finally, the linkage of suicide morbidity and mortality data to the Collaborative Data Synthesis for … Impact of the Garrett Lee Smith youth suicide prevention program on suicide mortality. … National Transit Database - Safety & Security Time Series Data Florida Department of Health Florida Death … Rate Query System Florida Health Florida Injury Surveillance Data System Healthy Minds Network

296. Mrsa-Screening-2010 Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
     January 01, 2010 - A number of analyses suggest that MRSA infections are associated with increased mortality and cost … O Health outcomes: morbidity (including complications of MRSA infection), case-fatality, mortality … outcomes (including MRSA acquisition and infection) and health outcomes (including morbidity and mortality … Health outcomes, including morbidity and mortality, are also depicted. … Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus

297. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
     November 30, 2011 - treatment because it is strongly associated with continued freedom from viremia as well as reductions in mortality … Intermediate outcomes, such as viremia and histologic changes, and ultimate health outcomes, such as mortality … changes to improve health outcomes and reduce HCV transmission Final outcomes  Morbidity and mortality … Estimating future hepatitis C morbidity, mortality, and costs in the United States. … A sustained virologic response reduces risk of all-cause mortality in patients with hepatitis C.

298. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0407_01-20-2011.pdf
     January 01, 2011 - endovascular intervention; KQ4: endovascular intervention, bypass surgery Outcome(s): Improvements in mortality

299. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
     December 01, 2015 - Mortality (all-cause or hepatic) •! Cirrhosis •! Hepatic decompensation •! … Short-term mortality SRC Literature Analysis: •! … Mortality and long-term hepatic complications SRC Literature Analysis: •! … , but found no difference in short-term mortality. … mortality, HCC, and other complications of ESLD •!

300. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
     December 01, 2015 - Mortality (all-cause or hepatic) •! Cirrhosis •! Hepatic decompensation •! … Short-term mortality SRC Literature Analysis: •! … Mortality and long-term hepatic complications SRC Literature Analysis: •! … , but found no difference in short-term mortality. … mortality, HCC, and other complications of ESLD •!