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261. Disposition of Comments for Treatment Strategies for Patients With Peripheral Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_disposition-comments.pdf
     May 29, 2013 - Since 1995, the routine use of statin therapy has reduced morbidity and mortality from CV and peripheral … What is the significance of a mortality point estimate for Cilostazol There are two types of tables … The significance (p-values) for the mortality point estimate for cilostazol compared to other therapies … The conclusion that "appears to be a trend toward a benefit of endovascular intervention" on mortality … The term “trend toward a benefit of endovascular intervention” on mortality was removed from the KQ

262. Sleep-Apnea Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_surveillance.pdf
     April 01, 2012 - The two studies of cardiovascular mortality did not have consistent findings, and the two studies of … and all-cause mortality. … While one of these trials found that CPAP resulted in a higher mortality benefit, the other found no … Sleep disordered breathing and cancer mortality: results from the Wisconsin Sleep Cohort Study. … , cancer mortality Baseline sleep disordered breathing is associated with increased cancer mortality

263. Executive Summary CER 171: Noninvasive Testing for Coronary Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_executive.pdf
     March 01, 2011 - • How do tests compare with regard to improvement in clinical outcomes (e.g., MI, premature mortality … The frequency of all-cause mortality was low across studies in all settings. … Given the low incidence of mortality and MI in the studies previously noted, sample sizes in even the … The low incidence of mortality and MI suggests that study populations may generally have been at the … Chest pain in general practice: incidence, comorbidity and mortality.

264. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
     March 09, 2010 - Relevance JIA is associated with significant morbidity and mortality. … disease progression, symptoms (e.g., pain, symptom scores), or health status (e.g., functional ability, mortality … clinical remission, quality of life, growth, development, joint function, functional ability, and mortality … Specifically, we will examine mortality, malignancy, serious infection, hepatitis, bone marrow suppression … Joint function  Functional ability  School performance  Emotional / psychological status  Mortality

265. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
     June 16, 2010 - characterize the impact of EPOGEN® on progression-free and overall survival (see WARNINGS: Increased Mortality … Studies to determine whether Aranesp® increases mortality or decreases progression-free/recurrence-free … WARNINGS: INCREASED MORTALITY, SERIOUS CARDIOVASCULAR EVENTS, THROMBOEMBOLIC EVENTS, STROKE and INCREASED … At the same time, evidence is consistent with an increased risk of thromboembolic events and mortality … Recombinant human erythropoiesis- stimulating agents and mortality in patients with cancer: a meta-analysis

266. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
     March 01, 2011 - $20,000). 3 Thus VTE is an important patient safety issue that results in significant morbidity, mortality … hospitalized trauma patients, PE occurs in 1 of every 25 patients and is associated with considerable mortality … Outcomes measures  Symptomatic DVT  Symptomatic PE  Asymptomatic DVT  Bleeding  Mortality … DVT  Bleeding  Mortality Adverse effects of intervention(s) and treatment burden … will not be evaluated  Symptomatic deep vein thrombosis  Symptomatic pulmonary embolism  Mortality

267. Cesarean-Birth-2010 Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_executive.pdf
     January 01, 2010 - , and neonatal morbidity and mortality. … Outcome Measures for Each Key Question: Outcomes included route of birth, maternal morbidity and mortality … , and neonatal morbidity and mortality. … , and neonatal morbidity and mortality. … • Neonatal morbidity & mortality • Apgar score • NICU observation • NICU admission • Maternal-infant

268. Future Research Needs for Treatment of Obstructive Sleep Apnea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
     February 01, 2012 - OSA is an important public health issue, due to the considerable mortality and morbidity associated … Regardless of the relative difference in effects between groups, trials using mortality as an outcome … The trial duration and followup for mortality as an outcome would be measured in years, while trials … OSA is an important public health issue, due to the considerable mortality and morbidity associated … Sleep-disordered breathing and mortality: a prospective cohort study.

269. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0277_03-10-2008.pdf
     January 01, 2008 - HSCT is associated with high morbidity and mortality in all ages and all diseases.

270. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0086_04-01-2009.pdf
     January 01, 2009 - )  Cardiovascular disease is a major cause of morbidity and mortality in the elderly.

271. Topic Brief: Antenatal Care (pdf file)
     effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-antenatal-care.pdf
     April 01, 2021 - ___________________ Background • Antenatal care reduces maternal and perinatal morbidity and mortality … Maternal morbidity (e.g. gestational hypertension, pre-eclampsia, mental health outcomes) Maternal mortality … Quality of life outcomes including stress and anxiety Fetal/neonatal outcomes: Mortality; morbidity … Maternal morbidity (e.g. gestational hypertension, pre-eclampsia, mental health outcomes) Maternal mortality … Quality of life outcomes including stress and anxiety Fetal/neonatal outcomes: Mortality; morbidity

272. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
     March 10, 2010 - Consideration should be given to the presentation of the mortality data with the implied disappointment … that there was no decreased mortality related to the drugs. … While none of the studies showed decreased mortality on the intervention, none should even a trend … Noted, mortality data indicate no differences between comparators, however, follow-up for some of the … The point that the trials may not be long enough to capture mortality benefit is included in the text

273. Research White Paper: Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
     November 01, 2020 - captured in structured form (e.g., PHQ-9 item 9, adverse events, suicide ideation and behavior, and mortality … ............................................................................................... 10 Mortality … for depression (response, remission, recurrence, adverse events, suicide ideation and behavior, and mortality … Potential challenges related to the availability of PHQ-9, adverse event, suicide, and mortality data … This information will be useful to inform future implementations of the measures. 11 Mortality

274. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0030_06-19-2008.pdf
     January 01, 2008 - placement (with or without glycoprotein IIb/IIIa inhibitors) Outcome(s): Improved patient morbidity and mortality

275. Dispostion of Comments Report for Screening for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
     November 27, 2012 - The annual mortality is higher than stated in the document. … All-cause mortality is decreased in HCV patients who receive anti-viral treatment. … between SVR and mortality). … We have a very short window period to address this epidemic before the death rate triples and we have … Mortality is 12,000 deaths per year.

276. Antipsychotics-Adults Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
     August 01, 2012 - • Specific AEs: – Major: mortality, cerebrovascular disease- related events, development of diabetes … the following AEs, which were deemed to be most clinically important a priori: diabetes mellitus, mortality … . clozapine and ziprasidone; haloperidol vs. clozapine, olanzapine, quetiapine, and ziprasidone); mortality … Two trials each provided data on mortality for chlorpromazine versus clozapine and haloperidol versus … rates.

277. S16 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
     October 01, 2007 - Mortality rates from endarterectomy were 8-fold higher in the community than in the ACAS trial.29 Similar … Operative morbidity and mortality in community double that achieved in trials. Is it worth it? … No effect on total mortality/stroke rates. … Variation in carotid endar- terectomy mortality in the Medicare population. … Variation and changes in state-specific carotid endarterectomy and 30-day mortality rates, United States

278. Thrombosis plays a a key role in the pathophysiology of myocardial infarction-a leading cause of morbidity and mortality. There have been a number of devices proposed for mechanical thrombectomy in patients with in the setting of acute… | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/thrombosis-plays-a-a-key-role-in-the-pathophysiology-of-myocardial-infarction-a-leading-cause-of-morbidity-and-mortality-there-have-been-a-number-of-devices-proposed-for-mechanical-thrombectomy-in-patients-with-in-the-settin

279. serious-mental-illness-outcomes-140303 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-outcomes_research-protocol.pdf
     March 03, 2014 - (length of time in remission, decreased morbidity and mortality from psychiatric diagnosis) § Medical … health outcomes: Intermediate; long term (e.g., decreased morbidity and mortality from medical illness … Morbidity and Mortality in People with Serious Mental Illness. … Medical Directors Council; 2006 Monograph available at http://www.nasmhpd.org/docs/publications/MDCdocs/Mortality … docs/publications/MDCdocs/Morbidity%20and%20Mortality http://www.nasmhpd.org/docs/publications/MDCdocs/Mortality

280. Amended Protocol: Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rural-telehealth-amended-protocol.pdf
     February 25, 2021 - • Outcomes: o KQ1: Clinical outcomes for the identified conditions (patient-reported outcomes, mortality … cross-sectional studies) KQ2: None Outcomes KQ1: • Clinical outcomes such as patient-reported outcomes, mortality … Widening rural-urban disparities in all-cause mortality and mortality from major causes of death in … Racial/ethnic disparities in mortality: contributions and variations by rurality in the United States … Worsening Rural-Urban Gap in Hospital Mortality.