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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
    October 01, 2012 - EPC Investigator Other Experts Conclusion from SCEPC Statins significantly reduced the risk of mortality … or macroalbuminuria could lead to early initiation of ACEI or ARB treatment and reduced risk of mortality … CKD classification based on estimated GFR over three years and subsequent cardiac and mortality outcomes … New Evidence: Beta blockers significantly reduced the risk of mortality, MI, and … New Evidence: Low-protein diets did not significantly reduce risk of mortality,
  2. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
    July 06, 2015 - , cardiovascular mortality, nonfatal myocardial infarction, stroke, the composite endpoint of the latter … , cardiovascular mortality, nonfatal myocardial infarction, stroke, the composite endpoint of the latter … , cardiovascular mortality, nonfatal myocardial infarction, stroke, the composite endpoint of the latter … Association between use of renin- angiotensin system antagonists and mortality in patients with heart … ARB therapy was associated with reductions in the composite endpoint of cardiovascular mortality,
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
    June 04, 2010 - Major adverse events include: • Mortality • Cerebrovascular disease-related events • Development … • Major adverse events: mortality, cerebrovascular disease-related events, development of diabetes … Adults Children >12yrs Not recommended for use in children under 12 years Possible increased mortality … Safety and effectiveness in pediatric patients <18 years have not been established Increased mortality … Adults Safety and effectiveness in pediatric patients <16 have not been established Increased mortality
  4. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
    September 01, 2008 - insulin for glycemic control, and the well-documented importance of glycemic control in decreasing mortality … , cardiovascular mortality, or cardiovascular morbidity. … , cardiovascular mortality, and the combined outcome of cardiovascular morbidity and mortality, but these … All-cause mortality, Low No statistically significant differences in all-cause cardiovascular disease … mortality (OR = 2.93; 95% CI: 0.95 to 9.05), mortality and morbidity1 cardiovascular mortality (OR =
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
    May 24, 2010 - United States (and globally) have increased in the last decade, along with associated morbidity and mortalityMortality from CDAD is estimated at 7 percent of cases.1 Distribution of CDAD in the population is … Mortality 2. Recurrence 3. Clearance 4. Complications 5. CDAD-related colectomy rate 6. … CDAD mortality rates Prevention Intermediate Process Measures/Outcomes 1. … rate  Relapse/recurrent rates?
  6. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_executive.pdf
    October 01, 2010 - advances in CF over the past 25 years have improved measures of nutrition, pulmonary function, and mortality … , but no association was seen between the decline in FEV1 and mortality. … an association between percent predicted FEV1 and mortality. … No studies evaluated the association between protein turnover and mortality. … No studies evaluated the association between bone mineralization and mortality.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
    April 01, 2013 - The risks of mortality, myocardial infarction, stroke, target revascularization, and side branch occlusion … When we evaluated mortality and MACE in studies of 365 days or longer, we saw no significant difference … in mortality risk, although a single trial found a significant reduction in MACE. … When we evaluated mortality and MACE in studies of 365 days or longer, we saw no significant difference … in mortality risk, although a single trial found a significant reduction in MACE.
  8. effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
    January 01, 2015 - outcomes for KQ2: – All-cause mortality – Cardiovascular and cerebrovascular morbidity and mortality … Most studies evaluated all-cause or cardiovascular mortality or cardiovascular morbidity. … All-Cause Mortality, Cardiovascular Mortality, and Cardiovascular Morbidity Only one comparison had … disease mortality less than metformin. … Diabetes, heart rate, and mortality. J Cardiovasc Pharmacol Ther. 2002 Apr;7(2):117-29.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
    April 01, 2005 - Mortality in operated patients compared with the mortality in individually matched medically treated … Detailed Mortality Figure Detailed Mortality Figure Figure. … Letters A-D indicate that these studies reported mortality rates for both medical treatment and an invasive … Most studies, though reported only a single mortality rate at an unspecified time point. … rates between treatments, in resultant kidney function, with the caveat that improvement was reported
  10. effectivehealthcare.ahrq.gov/sites/default/files/diverticulitis-nomination-extra.pdf
    May 29, 2025 - Outcomes Resolution of diverticulitis, recurrent diverticulitis, avoidance of surgery, morbidity, mortality … colorectal cancer, recurrent diverticulitis, adverse events Resolution of diverticulitis, morbidity, mortality
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
    May 01, 2025 - , all-cause mortality, quality of life, and functional status? … asked several Contextual Questions about the relationship between finding advanced cancers and cancer deathrates and how MCSTs might impact healthcare use and costs for health systems and patients. … Cancer stage compared with mortality as end points in randomized clinical trials of cancer screening … Strong association between reduction of late-stage cancers and reduction of cancer- specific mortality
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
    March 13, 2012 - rate has been largely attributed to the fact that ovarian cancer typically presents at a much later … likely to identify slower growing tumors, may have only a limited impact on overall ovarian cancer mortality … , overall mortality • Adverse effects of intervention(s): see KQ 5 KQ 4: • Intermediate outcomes … Ovarian cancer screening was feasible but did not decrease incidence of index cancer or mortality. … Reducing ovarian cancer mortality through screening: Is it possible, and can we afford it?
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-heart_research-protocol.pdf
    April 18, 2012 - in the United States.18 Given these issues, identifying approaches that avoid early morbidity and mortality … glucose-level control and related physical health outcomes (e.g., health-related quality of life, mortalityExcess mortality of mental illness. Br J Psychiatry 1996;169(3):383-4. PMID: 8879735 3. … Cardiovascular morbidity and mortality in bipolar disorder. Ann Clin Psychiatry 2011;23(1):40-7. … Do deficits in cardiac care influence high mortality rates in schizophrenia?
  14. effectivehealthcare.ahrq.gov/products/copd-management/research
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research-appendix-c.xlsx
    January 01, 2024 - The impact of emergency department segmentation and nursing staffing increase on inpatient mortality … Effects of nurse-to-patient ratio legislation on nurse staffing and patient mortality, readmissions, … NA NA NA Showed a decrease in mortality and improvement in time to first medical contact No funding … within Massachusetts (Baseline N=29754, standardized mortality ratio 1.20±0.04 to Post-mandate N=30058 … Mortality rates were not significantly higher than at baseline in comparison hospitals (adjusted odds
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nursing-staff-shortages.pdf
    October 01, 2024 - Missed nursing care leads to higher mortality, lower patient satisfaction, and adverse events like … in 2014 and 2023, respectively.2 Higher levels of nurse staffing are associated with decreased mortality … , and higher quality of care.2 A multi-site study noted decreased length of stay, admissions, and mortality … is limited, use of temporary (i.e., agency) staff may result in worse outcomes and higher patient mortality … Effects of nurse-to-patient ratio legislation on nurse staffing and patient mortality, readmissions,
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
    January 01, 2014 - , cardiovascular mortality. … , cardiovascular mortality. … The largest study (good quality) showed a significant reduction in death rates with omeprazole; therefore … , cardiovascular mortality. … , cardiovascular mortality.
  18. S131 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
    October 01, 2007 - what extent they change rate ratio estimates and reduce bias in a study of statin treatment and 1-year mortality … The investigators found a mortality effect RR � 0.87 (95% CI, 0.81–0.94) in all age groups combined ( … A, Unadjusted mortality rate ratio estimates; B, Multi- variate adjusted mortality rate ratio estimates … Reliable assessment of the effects of treatment on mortality and major morbidity. II. … Paradoxical relations of drug treatment with mortality in older persons.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
    November 02, 2019 - Objectives for the Systematic Review Prostate cancer is common and results in considerable morbidity, mortality … • Prostate cancer specific survival/mortality • Metastatic-progression free survival • Metastases … • Prostate cancer specific survival/mortality • Metastatic free survival/metastases (lymph nodes/ … Prostate-cancer specific survival/mortality Metastatic-progression free survival Metastases Effect … /survival; prostate-specific mortality/survival; metastatic progression) and harms (bowel, bladder,
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
    April 01, 2013 - mental health system, heart disease was the leading cause of death.12 This excess of CVD-related mortalityExcess mortality of mental illness. Br J Psychiatry. 1996;169(3):383-4. PMID: 8879735. 6. … Cardiovascular morbidity and mortality in bipolar disorder. Ann Clin Psychiatry. 2011;23(1):40-7. … Mortality and medical comorbidity among patients with serious mental illness. … Do deficits in cardiac care influence high mortality rates in schizophrenia?

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