-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
October 01, 2012 - EPC Investigator Other Experts
Conclusion from SCEPC
Statins significantly reduced the
risk of mortality … or
macroalbuminuria could lead to
early initiation of ACEI or ARB
treatment and reduced risk of
mortality … CKD classification
based on estimated GFR over three years
and subsequent cardiac and mortality
outcomes … New Evidence:
Beta blockers significantly reduced the risk
of mortality, MI, and … New Evidence:
Low-protein diets did not significantly
reduce risk of mortality,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
July 06, 2015 - , cardiovascular mortality, nonfatal myocardial infarction, stroke, the composite
endpoint of the latter … , cardiovascular mortality, nonfatal myocardial infarction, stroke,
the composite endpoint of the latter … , cardiovascular mortality, nonfatal
myocardial infarction, stroke, the composite endpoint of the latter … Association between use of renin-
angiotensin system antagonists and mortality in patients with heart … ARB
therapy was associated with
reductions in the composite endpoint
of cardiovascular mortality,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
June 04, 2010 - Major adverse events include:
• Mortality
• Cerebrovascular disease-related events
• Development … • Major adverse events: mortality, cerebrovascular disease-related events, development
of diabetes … Adults
Children >12yrs
Not recommended for use in children
under 12 years
Possible increased mortality … Safety and effectiveness in pediatric
patients <18 years have not been
established
Increased mortality … Adults
Safety and effectiveness in pediatric
patients <16 have not been
established
Increased mortality
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
September 01, 2008 - insulin for glycemic
control, and the well-documented importance of
glycemic control in decreasing mortality … , cardiovascular mortality, or cardiovascular
morbidity. … , cardiovascular mortality, and the
combined outcome of cardiovascular morbidity and
mortality, but these … All-cause mortality, Low No statistically significant differences in all-cause
cardiovascular disease … mortality (OR = 2.93; 95% CI: 0.95 to 9.05),
mortality and morbidity1 cardiovascular mortality (OR =
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - United States (and globally)
have increased in the last decade, along with associated morbidity and mortality … Mortality from CDAD is estimated at 7 percent
of cases.1
Distribution of CDAD in the population is … Mortality
2. Recurrence
3. Clearance
4. Complications
5. CDAD-related colectomy rate
6. … CDAD mortality rates
Prevention Intermediate Process Measures/Outcomes
1. … rate
Relapse/recurrent
rates?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_executive.pdf
October 01, 2010 - advances in CF over the past 25
years have improved measures of nutrition,
pulmonary function, and mortality … , but no association was seen between the
decline in FEV1 and mortality. … an association between
percent predicted FEV1 and mortality. … No studies evaluated the association between protein
turnover and mortality. … No studies evaluated the association between bone
mineralization and mortality.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
April 01, 2013 - The risks of mortality,
myocardial infarction, stroke, target
revascularization, and side branch occlusion … When we
evaluated mortality and MACE in studies of
365 days or longer, we saw no significant
difference … in mortality risk, although a single
trial found a significant reduction in MACE. … When we evaluated mortality and
MACE in studies of 365 days or longer, we saw no
significant difference … in mortality risk, although a single
trial found a significant reduction in MACE.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
January 01, 2015 - outcomes for KQ2:
– All-cause mortality
– Cardiovascular and cerebrovascular morbidity and mortality … Most
studies evaluated all-cause or cardiovascular mortality
or cardiovascular morbidity. … All-Cause Mortality, Cardiovascular Mortality, and
Cardiovascular Morbidity
Only one comparison had … disease mortality less than metformin. … Diabetes, heart rate, and mortality. J Cardiovasc
Pharmacol Ther. 2002 Apr;7(2):117-29.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
April 01, 2005 - Mortality in operated patients compared
with the mortality in individually matched
medically treated … Detailed Mortality Figure
Detailed Mortality Figure
Figure. … Letters A-D indicate that these studies reported mortality rates for both medical treatment and an invasive … Most studies,
though reported only a
single mortality rate at an
unspecified time point. … rates between
treatments, in resultant
kidney function, with the
caveat that
improvement was
reported
-
effectivehealthcare.ahrq.gov/sites/default/files/diverticulitis-nomination-extra.pdf
May 29, 2025 - Outcomes Resolution of
diverticulitis, recurrent
diverticulitis,
avoidance of surgery,
morbidity, mortality … colorectal cancer,
recurrent diverticulitis,
adverse events
Resolution of
diverticulitis,
morbidity, mortality
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
May 01, 2025 - , all-cause mortality, quality of life, and
functional status? … asked several Contextual Questions about the relationship between finding
advanced cancers and cancer death … rates and how MCSTs might impact healthcare use
and costs for health systems and patients. … Cancer
stage compared with mortality as end points
in randomized clinical trials of cancer
screening … Strong association between reduction of
late-stage cancers and reduction of cancer-
specific mortality
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
March 13, 2012 - rate has
been largely attributed to the fact that ovarian cancer typically presents at a much later … likely to identify
slower growing tumors, may have only a limited impact on overall ovarian cancer mortality … , overall
mortality
• Adverse effects of intervention(s): see KQ 5
KQ 4:
• Intermediate outcomes … Ovarian cancer screening was feasible but did not
decrease incidence of index cancer or mortality. … Reducing ovarian cancer mortality
through screening: Is it possible, and can we afford it?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-heart_research-protocol.pdf
April 18, 2012 - in the
United States.18 Given these issues, identifying approaches that avoid early morbidity and
mortality … glucose-level control and related
physical health outcomes (e.g., health-related quality of life, mortality … Excess mortality of mental illness. Br J Psychiatry
1996;169(3):383-4. PMID: 8879735
3. … Cardiovascular morbidity and mortality in bipolar
disorder. Ann Clin Psychiatry 2011;23(1):40-7. … Do deficits in cardiac care influence high mortality rates in
schizophrenia?
-
effectivehealthcare.ahrq.gov/products/copd-management/research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research-appendix-c.xlsx
January 01, 2024 - The impact of emergency department segmentation and nursing staffing increase on inpatient mortality … Effects of nurse-to-patient ratio legislation on nurse staffing and patient mortality, readmissions, … NA NA NA Showed a decrease in mortality and improvement in time to first medical contact No funding … within Massachusetts (Baseline N=29754, standardized mortality ratio 1.20±0.04 to Post-mandate N=30058 … Mortality rates were not significantly higher than at baseline in comparison hospitals (adjusted odds
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nursing-staff-shortages.pdf
October 01, 2024 - Missed nursing care leads to higher mortality, lower patient satisfaction, and
adverse events like … in 2014 and
2023, respectively.2 Higher levels of nurse staffing are associated with decreased
mortality … , and higher quality of care.2 A multi-site study noted
decreased length of stay, admissions, and mortality … is limited, use of temporary (i.e., agency) staff may result in worse
outcomes and higher patient mortality … Effects of nurse-to-patient ratio legislation on nurse
staffing and patient mortality, readmissions,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
January 01, 2014 - , cardiovascular mortality. … , cardiovascular mortality. … The largest study (good quality) showed a significant
reduction in death rates with omeprazole; therefore … , cardiovascular
mortality. … , cardiovascular mortality.
-
effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
October 01, 2007 - what extent they
change rate ratio estimates and reduce bias in a study of statin
treatment and 1-year mortality … The investigators found a
mortality effect RR � 0.87 (95% CI, 0.81–0.94) in all age
groups combined ( … A, Unadjusted mortality rate ratio estimates; B, Multi-
variate adjusted mortality rate ratio estimates … Reliable assessment of the effects of treatment
on mortality and major morbidity. II. … Paradoxical relations of drug
treatment with mortality in older persons.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
November 02, 2019 - Objectives for the Systematic Review
Prostate cancer is common and results in considerable morbidity, mortality … • Prostate cancer specific survival/mortality
• Metastatic-progression free survival
• Metastases … • Prostate cancer specific survival/mortality
• Metastatic free survival/metastases (lymph nodes/ … Prostate-cancer specific survival/mortality
Metastatic-progression free survival
Metastases
Effect … /survival; prostate-specific mortality/survival; metastatic progression) and harms
(bowel, bladder,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
April 01, 2013 - mental health system, heart
disease was the leading cause of death.12
This excess of CVD-related mortality … Excess mortality of mental illness.
Br J Psychiatry. 1996;169(3):383-4. PMID: 8879735.
6. … Cardiovascular morbidity
and mortality in bipolar disorder. Ann Clin Psychiatry.
2011;23(1):40-7. … Mortality and medical
comorbidity among patients with serious mental illness. … Do deficits in cardiac care influence high
mortality rates in schizophrenia?