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81. Therapies for Clinically Localized Prostate Cancer: Update of a 2008 Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-therapies-update/research
    December 01, 2019 - While the SPCG-4 study found that RP reduced prostate cancer–specific mortality at 12 and 15 years, the … The SPCG-4 study found that RP reduced all-cause mortality at 15 years, but neither the SPCG-4 nor the … In the SPCG-4 trial, subgroup analyses showed reduced all-cause mortality among patients younger than … In the PIVOT, reduced all-cause mortality was identified among men with prostate-specific antigen >10 … Six nonrandomized comparison studies reported that all-cause and prostate cancer–specific mortality was

82. Can screening among the general adult male population for elevated PCA3 (also known as DD3) gene expression, to identify those at risk for prostate cancer who may be candidates for prostate biopsy, reduce morbidity and mortality? | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/can-screening-among-the-general-adult-male-population-for-elevated-pca3-also-known-as-dd3-gene-expression-to-identify-those-at-risk-for-prostate-cancer-who-may-be-candidates-for-prostate-biopsy-reduce-morbidity-and-mortality
    November 01, 2017 - identify those at risk for prostate cancer who may be candidates for prostate biopsy, reduce morbidity and mortality … identify those at risk for prostate cancer who may be candidates for prostate biopsy, reduce morbidity and mortality … identify those at risk for prostate cancer who may be candidates for prostate biopsy, reduce morbidity and mortality … identify those at risk for prostate cancer who may be candidates for prostate biopsy, reduce morbidity and mortality … gene-expression-to-identify-those-at-risk-for-prostate-cancer-who-may-be-candidates-for-prostate-biopsy-reduce-morbidity-and-mortality

83. Cancer-Ovarian-Contraceptives Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
    June 01, 2013 - The high mortality rate in women with ovarian cancer is largely attributed to the later stage at presentation … found an increased risk of cervical cancer mortality among OC users, with a trend toward increased mortality … , and endometrial cancers, and increases in breast cancer incidence and mortality. … Mortality was increased to a lesser degree than incidence. … quality of life, as well as mortality, into these analyses.

84. Therapies for Clinically Localized Prostate Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-therapies-update/clinician
    December 01, 2019 - Prostate cancer–specific mortality : The SPCG-4 study found that RP reduced prostate cancer–specific … mortality at 12 and 15 years; however, PIVOT found no statistically significant difference at 12 years … All-cause mortality : The SPCG-4 study found that RP reduced all-cause mortality at 15 years, but neither … However, evidence was insufficient to determine the comparative effectiveness of RP and WW for mortality … and prostate cancer–specific mortality were significantly lower in patients undergoing RP when compared

85. Evidence-Summary-CER-206-Sodium-And-Potassium-Intake-Effects-On-Chronic-Disease-Outcomes-And-Risk (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
    June 01, 2018 - and on total mortality? … , and on total mortality? … and on total mortality? … or CVD mortality, alone … , and on total mortality?

86. Evidence Summary: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
    October 01, 2019 - mucolytics, inhaled corticosteroids, inhaled antibiotics, 5-lipoxygenase inhibitor, and statins on mortality … • Titrated oxygen reduces mortality compared with high flow oxygen. … Titrated oxygen reduces mortality. … Mortality in the United States, 2017. NCHS Data Brief. 2018 Nov(328):1-8. PMID: 30500322. 3. … In-hospital mortality following acute exacerbations of chronic obstructive pulmonary disease.

87. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
    February 19, 2010 - rate from stroke was approximately 44.7 per 100,000 for Caucasian males, 70.5 per 100,000 for black … males, 44.0 per 100,000 for Caucasian females, and 60.7 per 100,000 for black females.5 Lower mortality … rates were seen in Hispanic, Asian and American Indian populations as compared with Caucasian populations … The final health outcomes include mortality and impact of therapy on the mRS, NIHSS, Barthel index, … Compressed Mortality File: Underlying Cause of Death, 1979-2005.

88. Executive Summary_Comparative Effectiveness Review No. 254: Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-executive-summary.pdf
    December 01, 2022 - • Evidence suggests remote intensive care units (ICUs) in rural areas result in no difference in mortality … rates compared to transferring patients to more distant locations for ICU care (2 studies; low SOE) … Widening rural- urban disparities in all-cause mortality and mortality from major causes of death in … Racial/ethnic disparities in mortality: contributions and variations by rurality in the United States … Worsening Rural-Urban Gap in Hospital Mortality.

89. Heart-Failure-Natriuretic-Peptide Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
    November 01, 2013 - ; cardiovascular mortality and morbidity outcomes were measured less frequently. … Generally, studies predicting short-term mortality (up to 31 days) and longer term mortality (24 months … Mortality All-cause mortality was the outcome in three studies,161-163 and in all three there was an … • Inclusion of all relevant endpoints: cardiovascular mortality, total mortality, days alive and not … Short-term mortality risk in emergency department acute heart failure.

90. Recombinant-Factor-Viia Clinician (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/recombinant-factor-viia_clinician.pdf
    October 01, 2010 - Usual Care Spontaneous intracranial hemorrhage* No effect on mortality or functional status. �� … , particularly at doses >40 µg/kg of patient body weight.† ��� Adult cardiac surgery No effect on mortality … risk for thromboembolic events when compared to usual care. ��� Body trauma* No consistent effect on mortality … respiratory distress syndrome. ��� No effect on thromboembolic events. ��� Brain trauma No effect on mortality … improvements in indirect outcomes (e.g., reversal of bleeding) with those of direct outcomes (e.g., mortality

91. Bladder-Cancer-Muscle-Invasive Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bladder-cancer-muscle-invasive_executive.pdf
    June 01, 2015 - rates, with no clear differences between radiation therapy and maximal TURBT, and did not attempt … Overall mortality, bladder–cancer- specific mortality Insufficient There was insufficient evidence … Mortality Low One study found increased risk of 10-year cancer- specific mortality and overall mortality … risk, or a trend toward decreased risk, of mortality vs. no NAC. … United States Cancer Statistics: 1999–2009 Incidence and Mortality Web-Based Report.

92. Executive Summary_Comparative Effectiveness Review No. 263: Management of Postpartum Hypertensive Disorders of Pregnancy (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
    May 01, 2023 - HDP can persist, worsen, or develop de novo after delivery, and may result in severe morbidity or mortality … For morbidity and mortality outcomes, despite numerous RCTs with thousands of patients (and infants … In the two RCTs reporting maternal mortality, there were no maternal deaths (insufficient evidence). … There was no evidence of a difference in mortality (6 RCTs, summary OR 0.60, 95% CI 0.26 to 1.35; low … Hypertensive Disorders in Pregnancy and Mortality at Delivery Hospitalization - United States, 2017

93. Evidence Summary - Comparative Effectiveness Review No. 249: Malnutrition in Hospitalized Adults: A Systematic Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-249-malnutrition-hospitalized-adults-evidence-summary_0.pdf
    October 01, 2021 - diagnosed with malnutrition (using Subjective Global Assessment [SGA]) may have higher hospital mortality … failure and diagnosed with malnutrition (using several different measurement tools) may have higher mortality … awaiting transplantation and diagnosed with malnutrition (using SGA) may have higher pre-transplant mortality … interventions (i.e., specialized nutrition care, protein/calorie supplementation) likely decrease mortality … Clinical outcomes of interest included mortality, length of stay, 30-day readmission, quality of life

94. Utilization and Clinical Data on In-Hospital Off-Label Uses of Recombinant Factor VIIa | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/recombinant-factor-viia/clinician
    March 01, 2020 - improvements in indirect outcomes (e.g., reversal of bleeding) with those of direct outcomes (e.g., mortality … Spontaneous intracranial hemorrhage * No effect on mortality or functional status . … [evidence medium] Body trauma * No consistent effect on mortality . … [evidence low] Brain trauma No effect on mortality , Glasgow coma scale , or hematoma … [evidence low] Liver transplantation * No effect on mortality, OR time, or ICU length

95. Hip-Fracture-Pain Clinician (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
    May 01, 2011 - . ��� Continuous versus single-dose modes of spinal anesthesia do not differ for either 30-day mortality … rates or changes in mental status. ��� Nerve Blocks: Reduce the intensity of acute pain (3-in-1, fascia … lumbar and sacral plexus blocks). ��� Reduce the incidence of delirium (NNT = 9).* ��� Do not affect mortality … rates (pre- and postoperative use). ��� Skin Traction: Does not reduce intensity of acute pain. ��� … Background Information Among elderly patients with hip fracture from low-impact injury, mortality rates

96. Pulmonary Arterial Hypertension: Screening, Management, and Treatment | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/hypertension-pulmonary-arterial/research
    December 01, 2019 - confidence interval [CI], 1.72 to 3.41) and presence of pericardial effusion were strong predictors of mortality … (summary HR 2.43; 95% CI, 1.57 to 3.77) RA size and uric acid were also predictive of mortality, but … fractional area change (FAC) showed no significant ability to predict mortality, and data on TAPSE were … Although no studies were powered to detect a mortality reduction, monotherapy was associated with improved … Comparisons of different drug combinations were inconclusive regarding a mortality reduction but suggested

97. Glasgow Coma Scale for Field Triage of Trauma: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/field-triage-glascow/research-2017
    March 01, 2020 - with slightly greater discrimination than the mGCS or Simplified Motor Score (SMS) for in-hospital mortality … For in-hospital mortality, the tGCS is associated with slightly greater discrimination than the mGCS … that for every 100 trauma patients, the tGCS correctly discriminates 1 to 3 more cases of in-hospital mortality … from cases without in-hospital mortality than the mGCS or SMS. … The tGCS is associated with slightly greater discrimination than the mGCS or SMS for in-hospital mortality

98. Cer-243-Prehospital-Airway-Management-Appendix-F-1 0 (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-appendix-f-1_0.xlsx
    January 01, 2016 - In hospital mortality ITT Technique/Device ETI: RSI vs. … In-hospital mortality As treated Technique/Device ETI: RSI vs. no medication Mortality 25% (191/774) … , 2010 4 ETI RSI 496 ETI No medication (no RSI = no medication) 381 Mortality In-hospital mortality As … Mortality: time period not specified As treated NA NA Mortality: 84.2% vs.56.3%, NR OR for survival … In-hospital mortality As treated Technique/Device ETI: sedation-facilitated vs. no medication Mortality

99. Blood-based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cell-free-dna-draft-report.pdf
    December 01, 2024 - and all-cause mortality? … , all-cause mortality, quality of life, and functional status. … • Outcomes: Varied by KQ; aggregate cancer mortality, all-cause mortality, and quality of life for … excluded studies that were not powered for mortality outcomes. … The impact of cancer screening on all-cause mortality.

100. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
     February 01, 2008 - Disease-specific mortality rates have declined, and an estimated 1.8 million men living in the United … Overall and disease-specific mortality were infrequently reported. … • Disease-specific mortality: In SPCG-4, RP reduced prostate-cancer-specific mortality compared with … • Disease-specific mortality: ADT + EBRT reduced disease-specific mortality compared with EBRT alone … /survival: Vaccine may reduce overall mortality compared with nilutamide.