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41. Effects of Dietary Sodium and Potassium Intake on Chronic Disease Outcomes and Related Risk Factors | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/sodium-potassium/research-protocol
    January 01, 2019 - , CVD mortality, CHD mortality, renal disease mortality Stroke, coronary heart disease, myocardial … All-cause mortality CVD mortality CHD mortality Renal disease mortality Stroke Coronary heart … All-cause mortality CVD mortality CHD mortality Renal disease mortality Stroke Coronary heart … All-cause mortality CVD mortality CHD mortality Renal disease mortality Stroke Coronary heart … All-cause mortality CVD mortality CHD mortality Renal disease mortality Stroke Coronary heart

42. Failure To Rescue – Rapid Response Systems | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/mhs4-failure-rescue/rapid-research
    March 01, 2024 - this review, rapid response systems may have a large beneficial effect on the outcomes of hospital mortality … For pediatrics, rapid response systems may have a large impact on hospital mortality, but like adults … Modifications to the afferent and/or efferent limb were associated with a reduction in mortality and … Modifications to the afferent and/or efferent limb were associated with a reduction in mortality and … Overall, rapid response systems may have a large beneficial effect on the outcomes of hospital mortality

43. Malnutrition in Hospitalized Adults | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/malnutrition-hospitalized-adults/research
    April 01, 2022 - Clinical outcomes of interest included mortality, length of stay, 30-day readmission, quality of life … Evidence indicates malnutrition-focused hospital-initiated interventions likely reduce mortality and … ICU Inconclusive Tripathy et al. 2014 found MN associated with 1-year mortality (n=109, AOR: 2.94, 95% … ICU Inconclusive 1 study found MN associated with greater hospital mortality (Sheean et al. 2013, n= … Like our review, these reviews also found that nutrition-focused interventions decreased mortality.

44. Respectful Maternity Care: Dissemination and Implementation of Perinatal Safety Culture to Improve Equitable Maternal Healthcare Delivery and Outcomes (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/respectful-maternity-care-protocol.pdf
    September 16, 2022 - From 2018 to 2019, just ahead of the COVID-19 pandemic, maternal mortality rates in the US increased … rates persist for non-Hispanic Black women even when controlling for education, income, or socioeconomic … Maternal mortality rates in the United States, 2019 National Center for Health Statistics. … Maternal mortality rates in the United States, 2020 National Center for Health Statistics. … and case-fatality rates.

45. Data Points #17: Trends in bariatric surgery in Medicare beneficiaries | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/bariatric-surgery-trends/research
    December 01, 2019 - Postoperative mortality is low. … Morbidity and mortality rates following bariatric surgery continue to be a major concern. … While mortality was relatively low and rehospitalization rates moderate, it did not appear that bariatric

46. Nppv-Respiratory-Failure Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
    July 01, 2012 - rates (KQs 1–3) – Medical utilization (KQs 1–4), including ventilator-dependent days, rate of ventilator … instead of ICU mortality). … The median predicted mortality for enrolled patients was approximately 12 percent. … rates beyond hospitalization … rates beyond hospitalization.

47. Disposition of Comments Report for Procalcitonin-Guides Antibiotic Therapy (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
    October 05, 2012 - or 6 week mortality. … Row 1 is 28-day mortality Row 2 is in-hospital mortality This is clearly laid out in table 5. … in-hospital mortality. … Also 28-day mortality? … (mortality not increased).

48. Transitional Care Interventions To Prevent Readmissions for People With Heart Failure | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/heart-failure-transition-care/policymaker
    December 01, 2019 - harms of transitional care interventions (defined in Table 1 ) that aim to reduce readmissions and mortality … specific readmissions, the composite endpoint (which comprises all-cause readmission or death), and mortality … Multidisciplinary-HF clinic-based interventions reduced all-cause readmissions and mortality but not … Structured telephone support reduced HF-specific readmissions and mortality but not all-cause readmissions … and multidisciplinary- HF clinic interventions were effective in reducing all-cause readmissions and mortality

49. Interventions To Decrease Hospital Length of Stay | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/hospital-length-of-stay/report
    March 01, 2022 - Clinical pathways reduced LOS, readmission, and mortality (low to moderate quality evidence from a single … Length of Stay   Readmission   Mortality   Other   Intervention Type Case Management Author Comparison … RR: 0.665, 95% CI: 0.449 to 0.986, intervention tended to reduce early mortality low Baratloo et al. … RR: 0.665, 95% CI: 0.449 to 0.986, intervention tended to reduce early mortality low Baratloo et al. … Similarly, findings varied for readmissions and mortality.

50. Comparative Safety of Conventional and Atypical Antipsychotic Medications: Risk of Death in British Columbia Seniors | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/atypical-antipsychotics-seniors-death/research
    November 01, 2017 - Main Outcome Measures: All cause mortality. … Multivariable adjustment resulted in a 180-day mortality ratio (MR) of 1.32 (1.23-1.42). … The increase in mortality was highest in users of haloperidol (MR = 2.14; 95% CI: 1.86 to 2.45) but lower … for loxapine (MR = 1.29; 95% CI: 1.19 to 1.40).The greatest mortality increase occurred with use of … Conclusions Elderly patients using conventional APMs are at no lower risk of mortality than those using

51. Linking Dental Services to Treatment Outcomes for Chronic Kidney Disease: A Rapid Response Review July 2024 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/treatment-outcomes-chronic-kidney-rapid-research.pdf
    July 21, 2024 - ns: CAD, Cerebrovascular disease, malignancy- associated mortality ↑ other cause mortality Yu … on all-cause mortality (ACM). … Linked Mortality Study. … rates of end-stage renal disease: A systematic review and meta-analysis. … rate in hemodialysis: a 3-year cohort study.

52. Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment: Comparative Effectiveness Update | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cancer-anemia-update/research
    December 01, 2019 - There were fewer thromboembolic and on-study mortality adverse events when ESA treatment was delayed … Mortality was increased during the on-study period (pooled hazard ratio [HR], 1.17; 95% CI, 1.04 to 1.31 … There was one additional death for every 59 treated patients when the control arm on-study mortality … There was no discernible increase in mortality with ESA use over the longest available followup (pooled … An increase in mortality accompanied the use of ESAs.

53. Comparative Effectiveness of Coronary Bypass Surgery and Percutaneous Coronary Interventions for Multivessel Disease: A Pooled Analysis of Individual Patient Data from Ten Randomized Trials (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
    February 01, 2010 - Patient age modified the effect of treatment on mortality, with hazard ratios of 1.25 (0.94-1.66) in … The primary outcome measure of this study was all-cause mortality over all available follow-up, and … Eight-year mortality in the Emory Angioplasty Versus Surgery Trial (EAST). … Data show overall unadjusted mortality rates for patients with diabetes and without diabetes. … Data show overall unadjusted mortality rates for patients aged less than 55 years, 55 to 64 years, and

54. Patient Safety Practices Focused on Sepsis Prediction and Recognition | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/sepsis/rapid-research
    April 01, 2024 - Shock Early Management Bundle), patient outcomes (hospital or intensive care unit (ICU) length of stay, mortality … process measures (low strength of evidence), but evidence was insufficient about length of stay or mortality … primary studies of adults, the PSPs did not demonstrate an effect on clinical process, length of stay, or mortality … In primary studies of adults, evidence was insufficient in the prehospital setting for mortality, length … In the emergency department setting, strength of evidence was low for mortality and clinical process

55. CER 215 Executive Summary: Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
    March 01, 2019 - TCA 3 RCTs16-18 Any AE, cognitive impairment, hospitalization, mortality, serious AE, withdrawal due … SSRI 4 RCTs 7-9,21 1 OBS27 Any AE, blood pressure, cognitive function, hospitalization, mortality, … SSRI 2 RCTs10,20 Any AE, blood pressure, falls, fractures, mortality, serious AE, weight, withdrawal … fluoxetine (++)9 Insufficient evidence: mortality SSRI vs. … citalopram (++)20 Inconclusive: falls, fractures, mortality No data SSRI vs.

56. Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_policymaker.pdf
    August 01, 2016 - transitional care interventions (defined in Table 1 on page 2) that aim to reduce readmissions and mortality … multicomponent interventions, as these interventions are effective on all-cause readmissions and mortality … üüMultidisciplinary-HF clinic-based interventions reduced all-cause readmissions and mortality but … NA ��� HF-specific readmission 7 1,790 Reduced 14 ��� Composite endpoint 3 977 No benefit NA ��� Mortality … 2 264 No benefit NA ��� HF-specific readmission 1 158 – NA ��� Composite endpoint 1 106 – NA ��� Mortality

57. Cancer-Anemia-Update Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
    April 01, 2013 - (in this review, referred to as “on-study mortality”; overall strength of evidence moderate). … Table C shows on-study mortality data. 4 Table C. … On-study mortality Variable Darbepoetin vs. Epoetin Epoetin vs. Control Darbepoetin vs. … A detectable relative increase in mortality risk, which is higher with lower underlying absolute mortality … Whether there are subgroups at higher and lower risk of adverse events and mortality is unclear.

58. Comparative Effectiveness Research to Improve Anemia Management and Cardiovascular Disease Outcomes in End-Stage Renal Disease (ESRD) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/renal-disease-anemia/abstract
    December 01, 2019 - the effectiveness of lower versus higher cumulative IV iron doses on CV-related hospitalization and mortality … , infection-related hospitalization and mortality, all cause mortality, and quality of life. … comparative effectiveness of prescribed antihypertensive therapeutic regimens with all cause and CVD mortality … For Aim 2, we will quantify the association of cumulative dose of iron with mortality and the other clinical … Outputs : At least two scientific reports will be generated regarding the different outcomes examined (mortality

59. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
    March 01, 2011 - In addition, the death rate from cardiovascular disease in adults with type 2 diabetes is two to four … , cardiovascular mortality and morbidity, or microvascular complications. … All-cause mortality 2. Cardiovascular mortality 3. … Metformin was associated with slightly lower all-cause mortality and cardiovascular disease mortality … of all-cause mortality in observational studies, but the results were inconsistent between trials

60. MEDICAL MANAGEMENT OF CONGESTIVE HEART FAILURE AND THE EFFECTIVENESS OF ISOSORBIDE DINITRATE AND HYDRALAZINE (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
    March 01, 2010 - Conclusions: H-ISDN was not associated with significant reduction in mortality or hospitalization for … However, there was very little difference in unadjusted mortality between African- American (35.3%), … We found no significant association between H-ISDN and mortality within racial/ethnic subgroups with … Effect of vasodilator therapy on mortality in chronic congestive heart failure. … Accuracy and completeness of mortality data in the Department of Veterans Affairs.