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341. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
     January 01, 2017 - , aripiprazole, risperidone, quetiapine, and ziprasidone were similar in function, quality of life, mortality … – Key Question 1: Functional outcomes, quality of life, response and/or remission rate, mortality … The mortality rate is low in SGA trials and cohort studies (0 to 1.17%), and there were no differences … in mortality rates between olanzapine and risperidone or asenapine, risperidone and quetiapine, or … Comparative evidence on the risk of cardiovascular or all- cause mortality was not available for the

342. Management of Postpartum Hemorrhage | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/hemorrhage-postpartum/research-protocol
     December 01, 2019 - Adverse Outcomes Associated with Postpartum Hemorrhage PPH is one of the leading causes of maternal mortality … loss, transfusion, ICU admission, anemia, or length of stay and/or in final health outcomes such as mortality … products Anti-shock garment Birth setting Facility characteristics Blood loss Mortality … Reducing maternal deaths through state maternal mortality review. … Maternal mortality from hemorrhage. Semin Perinatol 2012 Feb;36(1):48-55. PMID: 22280866.

343. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
     July 01, 2011 - Based on the considerable mortality and morbidity associated with it and its attendant comorbidities, … In addition, mortality due to cardiovascular disease, diabetes, motor vehicle accidents, and other causes … The two studies of cardiovascular mortality did not have consistent findings, and the two studies of … • There were 2 quality A studies that evaluated cardiovascular mortality. … OSA treatments • There were 2 retrospective studies that evaluated mortality in Surgery vs.

344. First and Second Generation Antipsychotics for Children and Young Adults-Comparative Effectiveness Review Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antipsychotics-children-update/research-protocol
     April 01, 2020 - harms within conditions in terms of medication-associated adverse effects categorized as major (e.g., mortality … Major adverse effects* Mortality Cerebrovascular disease-related events Development of diabetes … Safety and effectiveness in pediatric patients <18 years have not been established Increased mortality … Adults Safety and effectiveness in pediatric patients <16 have not been established Increased mortality … increased mortality in elderly patients with dementia-related psychosis severe neutropenia

345. hemorrhage-postpartum-protocol-140611 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
     June 11, 2014 - Adverse Outcomes Associated with Postpartum Hemorrhage PPH is one of the leading causes of maternal mortality … • Blood loss • Transfusion • ICU admission • Anemia • Length of stay Final outcomes • Mortality … characteristics • Blood loss • Transfusion • ICU admission • Anemia • Length of stay • Mortality … Reducing maternal deaths through state maternal mortality review. … Maternal mortality from hemorrhage. Semin Perinatol 2012 Feb;36(1):48-55. PMID: 22280866. 32.

346. Physiologic Predictors of the Need for Trauma Center Care: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/predictors-trauma-care/research-protocol
     December 01, 2019 - Indicators that have been used or proposed include in-hospital mortality, measures of resource use (e.g … Indicators of serious injury In-hospital mortality Resource use/intervention standards or lists … Relationship between American College of Surgeons trauma center designation and mortality in patients … A national evaluation of the effect of trauma-center care on mortality. … The value of traditional vital signs, shock index, and age-based markers in predicting trauma mortality

347. Expanded Guidance on Selected Quantitative Synthesis Topics | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/quantitative-synthesis-expanded-methods/methods
     December 01, 2019 - In reporting the result, it would be hard to avoid the suggestion of a reduction in mortality even if … Control Rate Meta-Regressions Patients with higher underlying risk for mortality and other outcomes … hazards of using a naïve meta-regression model to assess the relation between the control rate and mortality … per 100 Person-Years Rate Ratios Number Needed To Treat (5 years) Total Mortality CHD Mortality … All CV Events Total Mortality CHD Mortality All CV Events Adapted by permission from

348. Disposition of Comments_Comparative Effectiveness Review No. 262_Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-disposition-comments.pdf
     November 07, 2023 - We did not repeat the assessment for mortality in this section (for baclofen or for other drugs). … The dose response issue we found was in the mortality assessment (not in the assessment for other … For mortality, we routinely list this outcome under potential benefits because we want to look for … , it makes sense to think of reduced mortality under potentially beneficial health outcomes. … In the case of baclofen, we do have a section on Mortality (with its own header) in the harms KQ

349. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colorectal-cancer-screening_research-protocol.pdf
     May 18, 2011 - Incidence and mortality rates for CRC have declined over the past 2 decades. 1 This decrease has been … DNA testing to screen for colorectal cancer in reducing morbidity (colorectal cancer incidence) or mortality … Outcomes KQ 1: Final Health Outcomes 1) CRC-specific or all-cause mortality 2) CRC incidence … (CRC) Fecal DNA Screening Colorectal Cancer Decreased Colorectal Cancer or All-Cause Mortality … , and CRC-specific mortality.

350. Alcohol-misuse-drug-therapy-140326 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
     January 27, 2012 - more than $220 billion.6,7 Alcohol misuse is estimated to be the third leading cause of preventable mortality … is, threefold to fourfold increased rates of early mortality.18-20 They are associated with hypertension … The low use of medications for alcohol dependence could contribute to unnecessary morbidity and mortality … Per capita alcohol consumption and all-cause mortality in Canada, 1950-98. … Mortality attributable to harmful drinking in the United States, 2000.

351. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
     December 16, 2011 - before and after 24 weeks’ gestation) for GDM to reduce maternal, fetal, and infant morbidity and mortality … treatment  Comparators: No test for GDM  Outcomes: Maternal, fetal, and infant morbidity and mortality … brachial plexus injury (permanent and transient), birth injury, hypoglycemia, hyperbilirubinemia, mortality … brachial plexus injury (permanent and transient), birth injury, hypoglycemia, hyperbilirubinemia, mortality … For KQ2, outcomes include short- and long-term maternal, fetal, and child morbidity and mortality as

352. Public-Reporting-Quality-Improvement Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_executive.pdf
     July 01, 2012 - Mortality was often the focus in studies of hospitals and was also the primary outcome in one study … Most of the studies found a decrease in mortality, although these results are not uniformly consistent … Reduction in mortality: Public reporting was associated with a small decline in mortality after controlling … for trends in reductions in mortality. 19 Hospitals (18) Individual clinicians (1) Moderate Quality … Increase in mortality: In one study, an increase in mortality was attributed to public reporting.

353. Er r or Rate Reduction Regarding Lower Limb Prosthesis (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
     March 16, 2017 - emotional health (e.g., increased risk for cardiovascular disease,3 anxiety, and depression4) and higher mortality … (estimated 5-year mortality rates for amputees range between 50%5 and 74%6; estimated 1-year mortality … At 6 months, 1 year, and 5 years after receipt of a LLP, (accounting for intervening mortality, subsequent … “Mortality Rates and Diabetic Foot Ulcers.” J. … “Reamputation, Mortality, and Healthcare Costs Among Persons with Dysvascular Lower-Limb Amputations

354. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/protocol-social-isolation.pdf
     January 01, 2013 - problems that have been associated with poor psychological and physical outcomes, as well as increased mortality … Social isolation, loneliness, and all-cause mortality in older men and women.

355. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
     December 09, 2009 - Objectives for the Systematic Review Background Hip fractures are a source of significant morbidity and mortality … Not only are short-term mortality rates high, but a large proportion of those patients who survive never … We will consider post-hospital mortality of women versus men to note if the pattern the same. … Mortality (30 day and up to 1-year postfracture) b. Functional status c. … to prefracture place of residence, health-related quality of life, health service utilization, and mortality

356. Data Points #9: Utilization of antidiabetic drugs among Medicare beneficiaries with diabetes, 2006-2009 | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/diabetes-drugs-utilization/research
     December 01, 2019 - thiazolidinedione, was found to be associated with myocardial infarction, major adverse cardiovascular events, mortality … from cardiovascular causes, and all-cause mortality.

357. Symposium on Methods for Developing and Analyzing Clinically Rich Data for Patient-Centered Outcomes Research - Part III | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/patient-outcomes-symposium/overview
     November 01, 2018 - Data with Health Insurance Claims Data—an Example with Aromatase Inhibitors, Tamoxifen, and All-Cause Mortality … Gamis Incorporating Initial Treatments Improves Performance of a Mortality Prediction Model for Patients

358. Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m² | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/weight-loss-surgery/research
     December 01, 2019 - long-term adverse effects, and we found no evidence regarding major clinical endpoints such as all-cause mortality … , cardiovascular mortality and morbidity, and peripheral arterial disease.

359. PCA3 Testing for the Diagnosis and Management of Prostate Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-test/research-protocol
     December 01, 2019 - Long-term health outcomes (clinical utility), including reduced mortality/ morbidity and improved quality … Long-term health outcomes (clinical utility), including reduced mortality/ morbidity, improved quality … KQ 3 Long-term outcomes : Prostate cancer-related mortality, morbidity, function, quality of life … Direct evidence of the impact of testing on health outcomes (e.g., mortality/ morbidity, quality of life … Long-term outcomes – morbidity, mortality, function, and quality of life Harms – treatment-related

360. Prognostic Tests (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
     June 01, 2012 - Anemia and mortality in heart failure patients a systematic review and meta-analysis. … Grouped mortality probabilities estimated by the first prognostic test Grouped mortality probabilities … predictions using 1st test Mortality prediction using both tests Observed mortality   900 4.0% 3.8% … predictions using 1st test Mortality prediction using both tests Observed mortality   100 (25%) 15.0% … while the observed mortality is 4.5 percent.