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301. What is the effectiveness of interventions intended to treat anxiety disorders in children (
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-is-the-effectiveness-of-interventions-intended-to-treat-anxiety-disorders-in-children-18-years-of-age-over-the-long-term-6-12-months-what-is-the-effectiveness-of-interventions-intended-to-prevent-the-development-of-anxi
     November 01, 2017 - Early diagnosis and appropriate treatment can minimize morbidity and mortality. … Understanding treatment effects and harms and instituting appropriate treatment can reduce morbidity and mortality … Understanding treatment effects and harms and instituting appropriate treatment can reduce morbidity and mortality

302. Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update) (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_executive.pdf
     September 01, 2014 - The NHANES III analysis reported a significant decrease in breast cancer mortality during 9 years of … Vitamin D and All-Cause Mortality No new RCTs were identified for the current report that assessed … the effect of vitamin D supplementation on risk for all-cause mortality. … Vitamin D supplementation had no significant effect on all-cause mortality (summary relative risk [ … Results of all-cause mortality and cancer have been described in previous sections.

303. Renal-Function Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
     June 13, 2013 - Short-term outcomes (all-cause mortality and MACE during the initial hospitalization or within 1 year … For Key Questions3 and 4, the outcomes of interest are: • Long-term outcomes (all-cause mortality and … MACE over at least 1 year of follow-up) • Short-term outcomes (all-cause mortality and MACE during … Short-term (<1 yr) outcomes -- MACE --all-cause mortality KQ3 Prognosis in suspected ACS … Short-term (<1 yr) outcomes -- MACE --all-cause mortality KQ4.2 Prognosis in stable population

304. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
     December 14, 2010 - routinely performed laparoscopically, and they have demonstrated reduced obesity-related morbidity and mortality … healthcare utilization/economics o quality of life measures • Adverse events: o Short-term: - mortality … o Long-term: - mortality - reoperation after bariatric surgery (i.e. band removal, band- to-RYGB … • Adverse events: o Short-term: - mortality - systemic medical complications (i.e. myocardial … infarction, stroke) o Long-term: - mortality - adverse effects of medications Timing: Minimum

305. Prostate-Cancer-Test Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
     October 14, 2011 -  Long-term health outcomes (clinical utility), including reduced mortality/ morbidity and improved …  Long-term health outcomes (clinical utility), including reduced mortality/ morbidity, improved quality … KQ 3  Long-term outcomes: Prostate cancer-related mortality, morbidity, function, quality of life … Direct evidence of the impact of testing on health outcomes (e.g., mortality/ morbidity, quality of … Long-term outcomes – morbidity, mortality, function, and quality of life Harms – treatment-related

306. Methods-Guidance-Applicability Methods (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
     January 01, 2011 - For example, outcome studies suggest that mortality after carotid surgery is affected by the experience … Variation in carotid endarterectomy mortality in the Medicare population. … For older patients, prostate cancer mortality may represent a small portion of overall mortality and … thus be less relevant than overall mortality. … The benefits of RP on cancer-specific and overall mortality appears to be limited to men under 65 years

307. Methods Guide Atkins (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/methods_guide_atkins.pdf
     January 01, 2011 - For example, outcome studies suggest that mortality after carotid surgery is affected by the experience … Variation in carotid endarterectomy mortality in the Medicare population. … For older patients, prostate cancer mortality may represent a small portion of overall mortality and … thus be less relevant than overall mortality. … The benefits of RP on cancer-specific and overall mortality appears to be limited to men under 65 years

308. For patients with chronic diseases where large numbers of physicians do not follow guideline based care, such as with asthma-the most common chronic disease, what are the most and least effective interventions to modify physician and other… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-patients-with-chronic-diseases-where-large-numbers-of-physicians-do-not-follow-guideline-based-care-such-as-with-asthma-the-most-common-chronic-disease-what-are-the-most-and-least-effective-interventions-to-modify-physic
     November 01, 2017 - poor care, effectiveness of guideline versus non-guideline care on patient outcomes such as morbidity, mortality … (Death rates are low for asthma but all are considered unnecessary. … Patients are having actual morbidity and mortality already and in some ways there is no where to go than

309. Rapid Evidence Product: Adverse Events Associated With COVID-19 Pharmaceutical Treatments (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
     March 01, 2024 - Six studies reported all-cause mortality; the risk was significantly lower in the intervention group … Thus, there is insufficient certainty of evidence for increased mortality in severely ill patients. … Six studies reported all-cause mortality; the risk was significantly lower in the intervention group … The differences between groups for risk of both “any serious adverse event” and all- cause mortality … There was no significant difference in risk of all-cause mortality in any study.

310. Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer: An Update of a 2008 Comparative Effectiveness Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-therapies-update/research-protocol
     December 01, 2019 - Potential benefits of regular PSA screening include early cancer detection and reduced mortality rates … trial reported a 0.40 percent absolute risk reduction in prostate cancer mortality, a relative risk … reduction of 44 percent, and no difference in overall mortality in men aged 50 to 64 over 14 years of … Outcomes The primary outcome is overall mortality or survival. … Mortality results from the Göteborg randomised population-based prostate-cancer screening trial.

311. Clopidogrel After Drug-Eluting Stent Implantation: Is Current Practice Sufficient? | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/stent-clopidogrel-practice/research
     January 01, 2020 - An independent mortality committee reviewed follow-up results to confirm deaths. … Follow-up was considered complete if the Mortality Committee confirmed the patient’s death or if the … Adjusted cumulative mortality rates using the 6-month landmark analysis   Figure 2B. … Adjusted cumulative mortality rates using the 12-month landmark analysis   Figure 3B. … Aspirin subgroup: adjusted cumulative mortality rates using the 6-month landmark analysis P-value

312. Management of Infantile Epilepsies | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/management-infantile-epilepsy/research
     March 01, 2023 - Surgical mortality for functional hemispherectomy/hemispherotomy and non-hemispheric procedures is rare … For surgical interventions, surgical mortality is rare for functional hemispherectomy/hemispherotomy … refractory seizures and care was withdrawn With functional hemispherectomy/hemispherotomy, surgical mortality … is rare. low Surgical Mortality 3 pre/post studies of Anatomic Hemispherectomy (n=26) 0 of 2 children … For surgical interventions, although studies reporting surgical mortality for functional hemispherectomy

313. Screening for and Management of Chronic Kidney Disease Stages 1-3 | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/kidney-disease-medicine/research-protocol
     December 01, 2019 - of studies have suggested that a GFR 30-59 mL/min/1.73 m 2 is associated with an increased risk of mortality … Outcomes for each question Benefits Clinical outcomes: Reduced mortality Reduced/delayed … Outcomes for each question Benefits Clinical outcomes: Reduced mortality Reduced … Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular … Albuminuria, impaired kidney function and cardiovascular outcomes or mortality in the elderly.

314. Assessing the Applicability of Studies When Comparing Medical Interventions | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-applicability/methods
     May 01, 2020 - For example, outcome studies suggest that mortality after carotid surgery is affected by the experience … Variation in carotid endarterectomy mortality in the Medicare population. … For older patients, prostate cancer mortality may represent a small portion of overall mortality and … thus be less relevant than overall mortality. … The benefits of RP on cancer-specific and overall mortality appears to be limited to men under 65 years

315. Since their introduction in 20xx, DES have been shown in clinical trials to decrease TLR (… (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
     January 01, 2010 - Thirty-month overall mortality was higher in patients who received BMS than DES both before (17.9% … As expected, mortality was higher in those with diabetes, renal failure, STEMI or CHF. … rates for patients in our population receiving either DES or BMS (5.4%/year vs. 6.6%/year) than previously … rates, including an early decrease in MI, than those who received BMS. … Long-Term Impact of Drug- Eluting Stents Versus Bare-Metal Stents on All-Cause Mortality.

316. Emerging Approaches to Diagnosis and Treatment of Non-Muscle-Invasive Bladder Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/bladder-cancer-non-muscle-invasive/research-protocol
     December 01, 2020 - primarily in men older than 60 and roughly twice as frequently in white compared to black men, 2 though mortality … Bladder cancer remains an important health problem, with no improvement in associated mortality since … e.g., Guidelines of the European Association of Urology or based on urinary biomarker tests) decrease mortality … cancer or recurrence of bladder cancer and effects of using biomarkers on clinical outcomes such as mortality … United States Cancer Statistics: 1999–2009 Incidence and Mortality Web-based Report. Atlanta: U.S.

317. heart-failure-readmission-protocol-130611 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_research-protocol.pdf
     June 10, 2013 - by clinical myocardial infarction (75 percent).17 They also have greater 30-day, 1-year, and 5-year case … fatality rates than white Americans.19 Men are usually more likely to develop HF than women,16-19 although … Mortality rate b. Functional status c. Quality of life d. Caregiver burden e. … National and regional trends in heart failure hospitalization and mortality rates for Medicare beneficiaries … Incidence and hospital death rates associated with heart failure: a community-wide perspective.

318. Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/mental-illness-heart/research
     December 01, 2019 - Structured Abstract Objectives Individuals with serious mental illness (SMI) have excess mortality

319. Lower Limb Prosthesis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prosthesis/research-protocol
     January 01, 2019 - health (e.g., increased risk for cardiovascular disease, 3 anxiety, and depression 4 ) and higher mortality … (estimated 5-year mortality rates for amputees range between 50% 5 and 74% 6 ; estimated 1-year mortality … KQ 7 At 6 months, 1 year, and 5 years after receipt of a LLP , (accounting for intervening mortality … "Mortality Rates and Diabetic Foot Ulcers." J. Am Podiatric Medical Assoc. 2008;98(6):489?93. … "Reamputation, Mortality, and Healthcare Costs Among Persons with Dysvascular Lower?

320. Antenatal Care | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/antenatal-care
     December 01, 2020 - spacing of visits versus routine frequency or spacing of visits Outcomes: maternal morbidity, maternal mortality … , fetal/neonatal morbidity and mortality, NICU, preterm birth, patient satisfaction, provider efficiency