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281. Cervical Ripening in the Outpatient Setting | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cervical-ripening/research
     March 01, 2022 - all comparisons, there was insufficient evidence on time from admission to vaginal birth, perinatal mortality … For all comparisons, there was insufficient evidence on other important outcomes such as perinatal mortality … Research Protocol | Dec 9, 2021 Maternal Morbidity and Mortality Research Protocol | Aug

282. Oral Diabetes Medications for Adults With Type 2 Diabetes: An Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/type-2-diabetes-medications-update/research
     December 01, 2019 - that assessed intermediate outcomes (e.g., hemoglobin A1c [HbA1c]), long-term clinical outcomes (e.g., mortality … We graded evidence as low or insufficient for long-term clinical outcomes of all-cause mortality, cardiovascular

283. Long-Term Care for Older Adults: A Review of Home and Community-Based Services Versus Institutional Care | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/long-term-care-adults/research
     December 01, 2019 - the impact of the setting on outcome trajectories for physical function, cognition, mental health, mortality … evidence suggested no differences in outcomes for physical function, cognition, mental health, and mortality

284. Combination Therapy Versus Intensification of Statin Monotherapy: An Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/high-cholestorol-medicines-update/research
     December 01, 2019 - Results All evidence for clinical outcomes (mortality, acute coronary events, and revascularization … lowered LDL-c better than intensification of statin monotherapy, but evidence for clinical outcomes (mortality

285. Diabetes Medications for Adults with Type 2 Diabetes: An Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/diabetes-update-2015/research
     December 01, 2019 - Cardiovascular mortality in studies over 2 years in duration was 50 to 70 percent higher for sulfonylureas … supports metformin as firstline therapy, given its beneficial effects on HbA1c, weight, and cardiovascular mortality

286. In patients with cerebral palsy (CP) and difficulties with feeding, what is the effectiveness of of anti-reflux procedure (since often done in conjunction with gastrostomy placement) or type of tube (J-tube or G-J tube versus typical PEG… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/in-patients-with-cerebral-palsy-cp-and-difficulties-with-feeding-what-is-the-effectiveness-of-of-anti-reflux-procedure-since-often-done-in-conjunction-with-gastrostomy-placement-or-type-of-tube-j-tube-or-g-j-tube-versus-typi
     November 01, 2017 - I think we should specifically look mortality as an outcome as well. … Harms from complications of surgical interventions, chest infections, morbidity, and mortality. … to suck, chew, and swallow, leading to under-nutrition, aspiration, decreased quality of life, and mortality

287. The Effect of Dietary Digestible Carbohydrate Intake on Risk of Cardiovascular Disease | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/risk-cardiovascular-disease/protocol
     December 01, 2023 - Background and Objectives Despite fluctuating trends in mortality rates in the last … SOE for end outcomes, including cardiovascular disease, stroke, and cardiovascular disease-related mortality … Cardiovascular disease mortality in the Americas: current trends and disparities. … Decline in Cardiovascular Mortality: Possible Causes and Implications. … Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries

288. Topic 0589 Cleaning and Monitoring of HAIs NSD SJ Clean (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0718-140819.pdf
     March 11, 2013 - (HAIs) creates a significant burden on Summary: the health care system in terms of morbidity and mortality … § HAI rates create a significant burden on the health care system, in terms of morbidity and mortality

289. Topic 0410 Imaging to Diagnose and Statge SCLC and NSCLC NSD SJ clean (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0491-140827.pdf
     February 19, 2014 - care, which often involves a combination of imaging modalities and biopsies Outcome(s): Morbidity, mortality … Lung cancer is the leading cause of cancer-related mortality in the US. § There are two main categories

290. Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/alcohol-misuse-drug-therapy/research-protocol
     January 01, 2021 - more than $220 billion. 6,7 Alcohol misuse is estimated to be the third leading cause of preventable mortality … is, threefold to fourfold increased rates of early mortality. 18-20 They are associated with hypertension … The low use of medications for alcohol dependence could contribute to unnecessary morbidity and mortality … Per capita alcohol consumption and all-cause mortality in Canada, 1950-98. … Mortality attributable to harmful drinking in the United States, 2000.

291. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
     November 24, 2014 - clinical failure rates and some P. aeruginosa strains produce toxins that increase complications and mortality … Most studies have shown an attributable mortality due to VAP of 10% or less. … As mortality due to VAP was not separated from all-cause mortality in the studies included in this … How mortality is included in “clinical response” is often poorly defined or not defined at all, or “ … One way to decrease “resistance” is to increase mortality as dead patients cannot spread bacteria but

292. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
     August 22, 2008 - over the past 25 years, resulting in improvements in measures of malnutrition, lung function, and mortality … per year per patient.6 Complications Associated with Cystic Fibrosis Although the morbidity and mortality … shorter height have also each been shown to be independently associated with increased morbidity and mortality … Mortality/ 30. mortality.mp. 31. death.mp. 32. Quality of Life/ 33. $quality of life.mp. 34. … Mortality/ 5. mortality.mp. 6. death.mp. 7. Quality of Life/ 8. $quality of life.mp. 9.

293. Alcohol-Misuse-Drug-Therapy Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
     January 27, 2012 - more than $220 billion.5,6 Alcohol misuse is estimated to be the third leading cause of preventable mortality … Effective Health Care AUDs cause substantial morbidity and mortality—threefold to fourfold increased … rates of early mortality.14-16 They are associated with hypertension, heart disease, stroke, cancer … Per capita alcohol consumption and all-cause mortality in Canada, 1950-98. … Mortality attributable to harmful drinking in the United States, 2000.

294. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
     June 01, 2011 - Despite the high rates of morbidity and mortality attributable to hypertension, control of the condition … Mortality and major Low (ACEI vs. … In 21 studies ARB) that reported mortality, MI, or clinical stroke as outcomes among 38,589 subjects … ARBs, and therefore the evidence to discern any differential effects between these drug classes on mortality … For evaluation of rarer events (e.g., mortality or angioedema) it may be worth combining data across

295. Stroke-Atrial-Fibrillation Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
     August 01, 2013 - embolic stroke, heart failure, and cognitive impairment; reduced quality of life; and higher overall mortality … Even more importantly, warfarin therapy was associated with a 26 percent reduction in all-cause mortality … intracerebral hemorrhage, subdural hematoma], major and minor bleed); other clinical outcomes (MI, mortality … • Apixaban reduced all-cause mortality in patients with AF. … Dabigatran and rivaroxaban appear to have similar all-cause mortality as warfarin.

296. Nephropathy-Contrast-Induced Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive.pdf
     October 01, 2015 - We found insufficient evidence to draw conclusions about the effect of N-acetylcysteine on mortality … The SOE also was low that intravenous sodium bicarbonate did not differ from intravenous saline in mortality … was insufficient to draw conclusions about potential differences between the two interventions in mortality … The SOE was insufficient that mortality, the need for renal replacement therapy, cardiac events, and … The SOE was insufficient that mortality, the need for renal replacement therapy, cardiac events, and

297. Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non–ST Elevation Myocardial Infarction | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/angina-heart-attack-treatments/research
     December 01, 2019 - antiplatelet and anticoagulant medications are prescribed to reduce and prevent ischemic events and mortality … The addition of GPIs to unfractionated heparin reduced the rate of mortality up to 30 days (OR 0.80;

298. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
     May 01, 2010 - Dichotomous outcomes (e.g., mortality and thromboembolic events) were compared using a random effects … Overall, these studies were of fair quality and had small sample sizes insufficient to evaluate mortality … Mortality differences (rFVIIa minus usual care) 8 Figure D. … Regarding the benefits and harms of rFVIIa, our findings include: • Mortality and thromboembolic events … Available evidence does not indicate that use of off-label rFVIIa reduces mortality or improves other

299. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
     September 08, 2011 - Background and Objectives for the Systematic Review Sepsis is a condition with high morbidity and mortality … sepsis and early initiation of antibiotic and goal-directed therapies have demonstrated a reduction in mortality … persistent or recurrent infection, antibiotic resistance; and Health outcomes such as morbidity, mortality … Nor would masked outcome assessors be relevant to mortality outcomes. … Nor would masked outcome assessors be relevant to mortality outcomes.

300. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
     December 20, 2011 - same reasons, uncertainty surrounds the BNP or NT-pro-BNP test’s ability to predict morbidity and mortality … the review will investigate whether BNP and NT-proBNP are independent predictors of morbidity and mortality … , or whether they add information to other methods used to predict morbidity and mortality. … KQ3 to KQ6: Mortality including all cause and HF; Morbidity including hospitalization (including HF … B-type natriuretic peptide-guided therapy for chronic heart failure reduces all-cause mortality compared