-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
January 01, 2011 - anemia is generally treatable, and
antianemic therapy is associated with reductions in mortality, morbidity … higher dosing regimens of ESA are associated with adverse events, such as increased
cardiovascular morbidity … and ferritin) to diagnose and manage iron-
deficiency anemia
Outcomes:
o Mortality
o Morbidity … The impact of anemia on cardiomyopathy, morbidity, and
mortality in end-stage renal disease. … Bone marrow biopsy morbidity: review of 2003. J Clin Pathol 2005 Apr;58(4):406-8.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - rates in the United States (and globally)
have increased in the last decade, along with associated morbidity … The vast majority of
severe morbidity and mortality is experienced in the elderly population.2-4 Residents … Increasing morbidity and mortality of C. difficile infection, the limited therapeutic options
and difficulty … Does effectiveness vary by patient characteristics: age, gender, co-morbidity, hospital vs. … predominantly clonal multi-institutional outbreak of
Clostridium difficile-associated diarrhea with high morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0368_11-08-2010.pdf
January 01, 2010 - These disorders have a high prevalence, carry substantial morbidity, affect quality of
life, and pose
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0495_05-24-2013.pdf
January 01, 2013 - listed above (i.e., compared to each other)
Outcome(s): Tumor response, changes in treatment decisions, morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0587-131115.pdf
March 06, 2013 - of NMIBC
Comparator(s): Various new and existing therapies and diagnostic approaches
Outcome(s): Morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
December 06, 2010 - Morbidity, mortality and other serious adverse events
ii. … as symptoms, joint damage,
physical functioning and/or long-term outcomes such as quality of life, morbidity … (KQ 1, 4)
(KQ 3, 4)
(KQ 2, 3, 4)
Final health outcomes
Quality of Life
Morbidity … life
• KQ3: harms, tolerability, adherence, adverse
effects (including patient reported symptoms,
morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
December 06, 2010 - Morbidity, mortality, and other serious adverse events
ii. Tolerability
iii. Adherence
iv. … as symptoms, joint damage, physical
functioning, and/or long-term outcomes such as quality of life, morbidity … (KQ 1, 4)
(KQ 3, 4)
(KQ 2, 3, 4)
Final health outcomes
Quality of Life
Morbidity … life
• KQ3: harms, tolerability, adherence, adverse
effects (including patient reported symptoms,
morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - complications impose a substantial public health burden
as they contribute significantly to mortality, morbidity … 2012.1
Medication Management of Type 2 Diabetes in 2014
Diabetes medications can effectively reduce morbidity … 1) for
the long-term clinical outcomes of all-cause mortality, cardiovascular and cerebrovascular
morbidity … 1) for the long-term clinical outcomes of all-cause mortality,
cardiovascular and cerebrovascular morbidity … following confounders in their analysis: age, sex, and co-morbid
conditions (defined by using a co-morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
September 22, 2011 - resistance, relapse rates, and
treatment side effects) and health outcomes (e.g., disease-
specific morbidity … In terms of health
outcomes, no studies reported morbidity, mortality, or
HCV transmission. … No
studies reported morbidity, all-cause mortality, or HCV-
specific mortality. … No evidence exists regarding mortality and
morbidity. … Again, no evidence addressed the effects of the
intervention on mortality or morbidity.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
October 05, 2012 - PR (#3) Results Critically III/Ventilator-Associated Pneumonia
Morbidity -- ICU LOS, again the 95% … Mortality at later endpoints is more often related to
underlying co-morbidities. … The ability of a study to detect an increase in
mortality or morbidity depends on how much Abx overuse … This late mortality, however, is more likely related to the
underlying co-morbidities. … , there were more total co-morbidities reported for
patients in the PCT arm.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0645-151012.pdf
August 05, 2015 - Early diagnosis and appropriate treatment can minimize morbidity and mortality.
§ A scan for existing
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0745-141009.pdf
September 03, 2014 - Uterine fibroids are the most common pelvic tumors in women and
are associated with significant morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-612-09-03-2013.pdf
January 01, 2013 - management of chronic health
problems and optimal transitional ages and reductions in mortality and morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
November 01, 2010 - dialysis or transplantation)
Reduced hospitalization for acute kidney injury (AKI)
Cardiovascular morbidity … worsened estimated GFR, hyperkalemia, hypotension, cough, hospitalization for
AKI, cardiovascular morbidity … dialysis or transplantation)
Reduced hospitalization for acute kidney injury (AKI)
Cardiovascular morbidity … worsened estimated GFR, hyperkalemia, hypotension, cough, hospitalization for
AKI, cardiovascular morbidity … including worsened
eGFR, hyperkalemia, hypotension, cough, hospitalization for AKI, cardiovascular
morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
December 01, 2014 - abdominal area that is out of proportion to total body fat is known to be an independent predictor of
morbidity … Because of even greater morbidity risk, therapeutic intervention is considered to
be urgently needed … Surgery carries significant risks of morbidity and mortality, and drug therapy can
have undesired side … treatment strategies for weight loss in obese patients have become increasingly important in
reducing morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - the Systematic Review
Type 2 diabetes is increasing in the United States and has a high burden of morbidity … All-cause mortality
Cardiovascular mortality
Cardiovascular and cerebrovascular morbidity (e.g … Question 2 are:
• All-cause mortality
• Cardiovascular mortality
• Cardiovascular and cerebrovascular morbidity … all-cause mortality, cardiovascular disease mortality, cardiovascular
and cerebrovascular disease morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
May 19, 2011 - Morbidity of primary treatment decision
c. Incidence of metastatic disease
d. … treatments
KQ4
KQ4 Short- and long-term outcomes
- Prostate-specific and all-cause
mortality
- Morbidity … Prostate-specific and all-cause mortality, incidence of metastatic disease, quality
of life, morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-gain-prevention_research-protocol.pdf
January 01, 2020 - www.effectivehealthcare.ahrq.gov
Published Online: March 14, 2012
2
Obesity Substantially Increases Morbidity … Are Needed
Several studies have shown that overweight individuals (BMI 25.0–29.9 kg/m2) may have
morbidity … Adults who have the greatest degree of obesity have worse morbidity and mortality than those
whose weight … is closer to overweight.17 For example, adults with a BMI ≥40 kg/m2 have more co-
morbidities than those … Morbidity and mortality risk associated with an overweight BMI in older
men and women.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/field-triage-glascow_research-protocol.pdf
February 25, 2016 - total Glasgow Coma Scale (tGCS) compared with the motor GCS (mGCS) score
for predicting mortality, morbidity … comparative
effectiveness of the tGCS compared with the mGCS on clinical outcomes (e.g., mortality,
morbidity … addresses the utility of the tGCS compared with the mGCS for predicting
clinical outcomes (mortality, morbidity … Mortality (prior to hospital arrival, in the emergency department, or
after hospital admission)
o Morbidity … mGCS
KQ1
Final health
outcomes
Mortality
Morbidity
Quality of life
KQ 3
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
January 01, 2009 - For instance, if a new test is intended to reduce
patient morbidity by detecting additional cases of … Potential patient benefits of testing include reducing patient mortality or
morbidity, improving health-related … within pathways that
are directly associated with higher order effects such as patient mortality and
morbidity … For example, full-body computed
tomography (CT) might lead to reduced morbidity and mortality due to … about rates of test effects that are associated with changes in
patient risk of mortality or serious morbidity