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effectivehealthcare-admin.ahrq.gov/products/c-diff-infections/research-protocol
December 01, 2019 - rates in the United States (and globally) have increased in the last decade, along with associated morbidity … The vast majority of severe morbidity and mortality is experienced in the elderly population. 2-4 Residents … Increasing morbidity and mortality of C. difficile infection, the limited therapeutic options and difficulty … Does effectiveness vary by patient characteristics: age, gender, co-morbidity, hospital vs. community … predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity
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effectivehealthcare-admin.ahrq.gov/products/diabetes-update-2015/research-protocol
December 01, 2019 - complications impose a substantial public health burden as they contribute significantly to mortality, morbidity … 1
Medication Management of Type 2 Diabetes in 2014
Diabetes medications can effectively reduce morbidity … 1 ) for the long-term clinical outcomes of all-cause mortality, cardiovascular and cerebrovascular morbidity … 1 ) for the long-term clinical outcomes of all-cause mortality, cardiovascular and cerebrovascular morbidity … following confounders in their analysis: age, sex, and co-morbid conditions (defined by using a co-morbidity
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effectivehealthcare-admin.ahrq.gov/products/weight-loss-surgery/research
December 01, 2019 - evidence regarding major clinical endpoints such as all-cause mortality, cardiovascular mortality and morbidity … patients are needed to assess overall safety and comparative effectiveness regarding diabetes-related morbidity
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
May 07, 2010 - one attributable risk factor for death throughout
the world,2 hypertension results in substantial morbidity … Despite the high morbidity and mortality attributable to hypertension, control remains
suboptimal. … o Mortality (all-cause, cardiovascular disease-specific, and cerebrovascular
disease-specific)
o Morbidity … as mortality (all cause, cardiovascular disease-specific, and
cerebrovascular disease-specific) or morbidity … o Mortality (all-cause, cardiovascular disease-specific, and cerebrovascular disease-
specific)
o Morbidity
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effectivehealthcare-admin.ahrq.gov/products/weight-loss-surgery/research-protocol
December 01, 2019 - techniques are now routinely performed laparoscopically and have demonstrated reduced obesity-related morbidity … Band and port-related morbidity after bariatric surgery: an underestimated problem.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
January 01, 2012 - Current data
suggest that risk of overweight- and obesity-related morbidity and mortality increases … The surgery carries significant risks of morbidity and mortality, and the drug
therapy has undesired
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effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
April 20, 2022 - or develop de
novo after discharge from hospitalization for the delivery, and may result in severe morbidity … ● Harms
o Severe adverse events* (e.g., electrolyte abnormalities, severe hypotension)
o Infant morbidities … * (e.g., eclampsia*, stroke)
● Newborn/child outcomes
o Infant morbidities* (e.g., respiratory depression … Breastfeeding
• Reduction (or generation) of health disparities
• Severe adverse events
• Severe infant morbidities … KQ 3
• Maternal morbidity and mortality
• Infant morbidities
• Breastfeeding
• Satisfaction with
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0655-131114.pdf
May 22, 2013 - community
based care, school, home), and sub-populations (e.g., sex/gender , age groups, youth
with co-morbidities … 12 years, 13-18 years)
o Racial/ethnic minority groups
o Socioeconomic strata
o Youth with co-morbidities
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/bariatric-surgery-trends_research.pdf
November 01, 2012 - Morbidity and mortality rates
following bariatric surgery continue to be a major concern.7
Data Points
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/mental-illness-outcomes_research-protocol.pdf
March 03, 2014 - First, the prevalence and morbidity of
SMI are striking. … (length of time in remission, decreased morbidity and mortality from
psychiatric diagnosis)
§ Medical … health outcomes: Intermediate; long term (e.g., decreased
morbidity and mortality from medical illness … Morbidity and Mortality in People with Serious
Mental Illness. … PowerPoint presentation available at
http://www.nasmhpd.org/docs/publications/MDCdocs/Morbidity%20and
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_executive.pdf
October 01, 2012 - Impact of Dementia
Dementia causes significant morbidity and mortality and
creates a substantial burden … people with dementia, such as
pain or discomfort; depressive symptoms; sleep quality;
health decline/morbidities … for informal caregivers of people with
dementia, such as depressive symptoms; sleep quality;
and morbidities … Among four other morbidity measures the evidence
was insufficient.
7
Evidence on dementia SCUs … Low
New/worsening
morbidity and various
discrete measures
Morbidity across multiple measures differed
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - are
available at www.effectivehealthcare.
ahrq.gov/reports/final.cfm.
2
may reduce cardiovascular morbidity … possibility that intensive
glycemic control has either no effect or a negative effect
on cardiovascular morbidity … Cardiovascular and cerebrovascular morbidity
(e.g., myocardial infarction and stroke)
4. … (continued)
Cardiovascular and Low A comparison of the risk of cardiovascular morbidity between metformin … and
cerebrovascular thiazolidinedione as monotherapy was inconclusive, with high imprecision and
morbidity
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/renal-mass-and-localized-renal-cancer-the-following-questions-are-recommended-to-address-the-healthcare-tests-andor-treatments-this-program-should-consider-what-indicators-can-be-used-to-predict-malignancy-andor-aggressivene
November 01, 2017 - What are the implications of renal functional outcomes (survival, morbidities, quality of life) in this … What is the role of competing risks of death, related to age and medical-co-morbidities, in managing … Patient Characteristics
Age, gender
Obesity (BMI and other measures)
Renal function
Medical co-morbidities … Health-related benefits of interest include the following: treatment-related morbidity, renal functional … This data should be evaluated based on timeframe after procedure as morbidity can differ between early
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effectivehealthcare-admin.ahrq.gov/products/respectful-maternity-care/protocol
October 01, 2022 - Background
Despite sizeable resources invested in US maternity care, severe maternal morbidity … , 9
Access to high-quality maternal health care is associated with reduced maternal and perinatal morbidity … of procedures and interventions
KQ 3:
Health outcomes for pregnant persons
Maternal morbidity … Severe Maternal Morbidity in the United States: A Primer Fund TC; October 28, 2021 2021. … Advancing Maternal Health Equity and Reducing Maternal Morbidity and Mortality: Proceedings of a Workshop
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/environmental-monitoring-in-healthcare-to-ensure-adequacy-of-housekeeping-cleaning-and-reduce-the-spread-of-hospital-acquired-infections-hais
November 01, 2017 - Hospital acquired infection (HAI) rates create a significant burden on the healthcare system in terms of morbidity … arise from the patient's "endogenous" microorganisms and be related to the patient's underlying co-morbidities … acquisition of HAIs from environmental reservoirs can cause significant patient harm in the form of increased morbidity
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effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - Current data suggest that risk of
overweight/obesity-related morbidity and mortality increases progressively
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
December 20, 2011 - For the same reasons, uncertainty surrounds the BNP or NT-pro-BNP test’s ability to predict
morbidity … As well, the review will investigate whether
BNP and NT-proBNP are independent predictors of morbidity … KQ3, KQ4 Inclusion: patients with all types of HF (with or without any co-morbidity). … KQ3 to KQ6: Mortality including all cause and HF; Morbidity including hospitalization
(including HF … Subgroup analyses for age, gender and co-morbidities will
be undertaken to assess clinical diversity
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effectivehealthcare-admin.ahrq.gov/products/ace-inhibitor-arb-update/research-protocol
December 01, 2019 - one attributable risk factor for death throughout the world, 2 hypertension results in substantial morbidity … Despite the high morbidity and mortality attributable to hypertension, control remains suboptimal. … reported)
Mortality (all-cause, cardiovascular disease-specific, and cerebrovascular disease-specific)
Morbidity … as mortality (all cause, cardiovascular disease-specific, and cerebrovascular disease-specific) or morbidity … Mortality (all-cause, cardiovascular disease-specific, and cerebrovascular disease-specific)
Morbidity
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effectivehealthcare-admin.ahrq.gov/products/procalcitonin/research-protocol
December 01, 2019 - Background and Objectives for the Systematic Review
Sepsis is a condition with high morbidity and mortality … Health outcomes such as morbidity, mortality, function, quality of life, and adverse events of therapy … Health outcomes, such as morbidity, mortality, function, quality of life, and adverse events of therapy … Length of stay
Antibiotic exposure
Accuracy for response to therapy
Health outcomes
Morbidity … Direct evidence of the impact of testing on health outcomes is shown by link A (morbidity, function,
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/does-the-use-of-cytochrome-p450-2c19-cyp2c19-testing-to-predict-response-to-clopidogrel-in-people-1-with-acute-coronary-syndrome-2-who-have-suffered-other-cardiovascular-disease-related-events-eg-ischemic-stroke-symptomatic-
November 01, 2017 - recurrent ischemic events, reduction of stent thromboses, reduction of cardiovascular-disease related morbidity … While clopidogrel may decrease morbidity and mortality associated with several cardiovascular diseases