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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
    June 06, 2011 - Methods A. … Our research team will use appropriate procedures to reduce bias and enhance consistency in our study-selection … These procedures include using dual reviewers to review abstracts and full-text articles for inclusion … eligibility and exclusion criteria; case management intervention and comparisons; the outcome-ascertainment method … NOTE: The following protocol elements are standard procedures for all protocols. VIII.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
    February 01, 2018 - Adjusted indirect comparison method of Bucher et al.5 ► 2. Logistic regression ► 3. … Random effects meta-regression • With only 2 sets of trials (e.g., A vs B; B vs C), Bucher’s method … Choice of NMA method • There has been no systematic evaluation of the comparative performance of NMA … methods … • Investigators should test relevant assumptions where possible, regardless of method chosen.
  3. effectivehealthcare.ahrq.gov/products/labor-nitrous-oxide/research-protocol
    May 11, 2011 - 3 percent used nitrous oxide (likely an overestimate considering how few U.S. facilities offer this method … on women’s self-reporting of analgesia use, it provides a general sense of the relative use of each method … The widespread use of nitrous oxide in other countries suggests it is an effective labor pain relief method … Inhaled self-administered nitrous oxide in a 50/50 mix (e.g., Nitronox) is the most common method of … this comparison is distinct from the assessment of the efficacy of nitrous oxide as a sole pain relief method
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_disposition-comments.pdf
    April 28, 2015 - The term “initial second line procedure” may be confusing. … I believe the term “second line procedure” or “second line therapy” suffices. … We deliberately used “initial” as some women may undergo multiple procedures or surgeries considered … Key Informant #1 Methods Methods are clearly defined and logical for this systematic review. … A universally accepted definition of postpartum hemorrhage and a universally accepted method to measure
  5. effectivehealthcare.ahrq.gov/products/health-care-quality-improvement/research
    February 20, 2013 - Methods Each EPC conducted a systematic review of the peer-reviewed literature. … This methods report relies on the final topic reports to highlight common lessons, identify implications … interventions, assessment of individual study quality and strength of evidence, meaningful synthesis, and methods … weaknesses in study design and incomplete reporting; and difficulty applying traditional systematic review methods … intervention characteristics and contextual factors, and development of additional systematic review methods
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
    September 23, 2016 - include clear descriptions of the population, setting, interventions, and comparison groups; a valid method … the past, this evidence will not undergo this sufficiency assessment process and will undergo the procedures … Assessment procedure to ascertain sufficiency of evidence: All studies will undergo quality assessment … for all intervention areas in Key Question 2 were to undergo full data abstraction and synthesis procedures … Those areas deemed insufficient would undergo limited data abstraction and synthesis procedures.
  7. effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
    January 01, 2012 - Although not different from within-drug or within-procedure/surgery comparisons, understanding the … Different Magnitude of Misclassification in Drug Exposure Versus Procedure Comparison Assessment of … On the other hand, assessment of exposure to surgery or procedure (especially major procedures that … For most implantable devices, removal is a major procedure and therefore likely to be captured accurately … adherence or no device failure, the question should be clearly stated and the appropriate design and/or method
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_disposition-comments.pdf
    November 01, 2010 - multiple studies using single-subject designs to be a valid way to evaluate the efficacy of a treatment methodProcedures for conducting the Thank you for your comments. … Rather, it comprises a wide array of ABA procedures and is delivered in a variety of settings. … Introductio n Suggested re-wording: strictly defined UCLA/Lovaas method, which relies heavily on … Methods The report does not define what constitutes a correct randomization procedure, and the ratings
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - The findings may have been different had a different analytical method been conducted. … in pain77 as clinically meaningful; findings may have been different with a different analytical method … Finally, invasive procedure which are richly reimbursed by insurance payers (epidural stimulators) … We agree that newer pharmaceutical agents and invasive procedures are more likely to have higher-quality … For nonpharmacologic treatments, invasive procedures involving devices (i.e., spinal cord stimulators
  10. effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - The findings may have been different had a different analytical method been conducted. … in pain77 as clinically meaningful; findings may have been different with a different analytical method … Finally, invasive procedure which are richly reimbursed by insurance payers (epidural stimulators) … We agree that newer pharmaceutical agents and invasive procedures are more likely to have higher-quality … For nonpharmacologic treatments, invasive procedures involving devices (i.e., spinal cord stimulators
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
    March 26, 2013 - not in surgical procedures. … Additional interventional procedures (endoscopy, interventional radiology) d. … Methods A. … Intervention characteristics include the specific OMBP method used and the coadministration of oral … be considered a one-stage procedure?
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-decision-support-tools_disposition-comments.pdf
    December 23, 2014 - TEP Reviewer #4 Methods P11. … Peer Reviewer #2 Methods Methods are all well justified, logical, appropriate and well described. … Peer Reviewer #3 Methods The statistical methods used are appropriate No action required. … The methods seem reasonable and well presented. … This is clearly described in the Methods Section.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
    April 01, 2016 - We welcome comments on this Methods Research Project. … Methods. … For the scientific systematic review community, eliminating key procedures meant to reduce reviewer … and the potential ramifications of streamlined methods. … EPC Methods: An Exploration of Methods and Context for the Production of Rapid Reviews.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
    April 30, 2014 - Introduction I have no clinical knowledge of the subject matter, but was still able to understand the procedures … Peer Reviewer #6 Methods The analytical process and methods were sound. Thank you. … Peer Reviewer #7 Methods Methods are well described and are appropriate. Thank you. … TEP #5 Methods No issues with search terms or statistical methods. Thank you. … the outcomes of interest to this report are rare, observational data may offer the only reasonable method
  15. effectivehealthcare.ahrq.gov/products/gout/research-protocol-2014
    July 17, 2014 - the procedures of the Methods Guide for Medical Test Reviews . … Data Abstraction and Data Management Data abstraction will follow the procedures described above. … For studies that assess the validity of an alternative diagnostic method against that of analysis of … strength of evidence by using guidance suggested by AHRQ for its Effective Health Care Program. 16 This method … given the limitations of the oldest, gold standard method, the newness of most methods that rely on
  16. effectivehealthcare.ahrq.gov/products/vitamin-d-calcium/research
    September 15, 2014 - between vitamin D alone or vitamin D plus calcium to selected health outcomes and to report on the methods … and procedures used for the interventional studies that aimed to assess the effect of vitamin D administration … on serum 25(OH)D concentrations, and to stratify key outcomes by methods used to assay serum 25(OH)D … Methods used to assay serum 25(OH)D in studies reporting on key outcomes diverged widely. … Studies suggest the method used to assay 25(OH)D may influence the outcomes of dose-response assessments
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rotator-cuff-tears-future_research.pdf
    February 01, 2013 - randomized controlled trials/ (71901) 18 exp Random Allocation/ (70749) A-2 19 exp double-blind method … / (108914) 20 exp single-blind method/ (14735) 21 clinical trial.pt. (460613) 22 (clin$ adj25 (trial … Prioritization Methods and Tools Specific Methods 1. … Stakeholders will then engage in a ranking procedure by using a web-based prioritization software through … Associated procedures: When should associated procedures be performed (distal clavicle excision, biceps
  18. effectivehealthcare.ahrq.gov/products/back-pain-treatment/research-protocol
    October 08, 2014 - Methods A. … Methods Guide for Effectiveness and Comparative Effectiveness Reviews. … https://effectivehealthcare.ahrq.gov/products/methods-guidance-de-novo-processes/methods/ . … Preventive Services Task Force Procedure Manual. AHRQ Publication No. 08-05118-EF. … https://www.uspreventiveservicestaskforce.org/uspstf08/methods/procmanual.htm .
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/systematic-review-integration_white-paper.pdf
    June 01, 2014 - We welcome comments on this Methods Research Project. … Methods research along with future EPC program methods workgroups are needed to address these challenges … These organizations suggest scanning the reference lists of existing reviews as a supplementary method … with EPC program methods for finding evidence. … used are consistent with EPC program methods.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
    February 25, 2014 - Reviewer 5 Methods The definitions for the outcome measures are stated in the Methods section, self … Reviewer 5 Methods The statistical methods are OK. Thank you. … important to define who (What percent of eligibles) participated and what core assessment and treatment procedures … It documents for each provider and all providers how well they provided each/all “Procedures (P)”. … Although the lack of clear evidence in favor of one method or combination of methods prohibits a definitive

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