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  1. effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
    January 01, 2013 - Available at www.effectivehealthcare.ahrq.gov/Methods-OCER.cfm. … Available at www.effectivehealthcare.ahrq.gov/Methods-OCER.cfm. … Available at www.effectivehealthcare.ahrq.gov/Methods-OCER.cfm. … The case-crossover design: a method for studying transient effects on the risk of acute events. … Case-control study proposals should clearly describe the control sampling method, employ a new-user design
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
    August 23, 2013 - that studies of risk prediction started with moderate strength of evidence (can refer to the GRADE method … Meta-Analysis software (Version 2.2.057; Biostat, Englewood, NJ) which uses the Dersimonian and Laird method … Most methods guidance (e.g., Cochrane, AHRQ) suggest methods to develop summary ROC’s. … I am not familiar with the method that seeemed to be used in this review (should be described more … The authors should cite references if they choose to stick with this method. Leeflang et al.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
    November 01, 2013 - Then, according to these decisions rules and procedures documented in protocols, EPCs assess individual … Overall, EPC and GRADE guidance both emphasize applying a structured, transparent method. … impact of unreported data through, for instance, tests for funnel plot asymmetry, a trim and fill method … EPCs should carefully document procedures used to grade strength of evidence (in the review’s Methods … Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
    January 01, 2013 - The AHRQ Project Officer then described successful and unsuccessful procedures used by other EPCs not … In this way, group members gained familiarity with the procedures of other EPCs, identifying shared … It also resulted in the elimination of two questions related to nonmesh procedures; expansion of questions … Methods Research Report. … For further details about submission, please see the EPC Procedure Guide.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
    September 29, 2014 - Peer Reviewer 1 Methods The authors explain that the methods used for this manuscript conform to those … independent assessment of study quality resulted in initially equivalent determinations, given the method … Peer Reviewer 9 Methods The methods are well described with what I consider appropriate inclusion and … Methods are adequate. … Peer Reviewer 11 Methods Appropriate statistical methods used?
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_disposition-comments.pdf
    May 04, 2015 - Peer reviewer #2 Methods Methods: I appreciate the rigor of two-person review and secondary review … of a frenotomy versus skilled lactation consultation support (or some other conservative management method … TEP reviewer #3 Methods Methods: Yes to all the above questions Thank you for your comment. … Inclusion criteria now incorporates all surgical/procedures used to describe frenulum division including … As any oral procedure will produce a small amount of post procedure bleeding, it would also be important
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
    November 06, 2012 - Peer Reviewer #1 Methods There appear to be reporting errors in the document. … clinically important differences, including relative and absolute differences and the distribution method … They note that the relative difference method incorporates baseline severity and the distribution method … If this approach is included with the category of the distribution method, then a better description … Reimbursement is still dependent on billing for procedures such as US, diathermy, e-stim, etc.
  8. effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_disposition-comments.pdf
    February 29, 2016 - This is the standard method for reporting/assessing minimum clinically important differences. … typically derived from change from baseline at a given “disease severity”-often using an anchor method … This is the standard method for reporting/assessing minimum clinically important differences. … of imaging and procedures. … on mechanisms of injury may underlie overuse of imaging and procedures.
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
    February 07, 2018 - Methods The methods for this comparative effectiveness review follow the guidance provided in the … Methods Guide for Effectiveness and Comparative Effectiveness Reviews. … Stat Methods Med Res. January 2017:962280217721246. 19. … Double Blind Method/ 50. … Single Blind Method/ 51. clinical trial/ 52. clinical trial, phase i.pt. 53. clinical trial
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_disposition-comments.pdf
    June 10, 2013 - text to the Methods section in the ES and full report Added to last paragraph to the ES methods … We did not report mean effect sizes if we could not report a pooled CI; this is not a standard method … and is not a method that is recommended in the AHRQ Methods guide. 72 Peer Reviewer 3 Executive … overall comment made, was there an attempt to do “Indirect Comparisons” as described in the AHRQ Method … Guide on CER (e.g., Bucher’s simple method)?
  11. effectivehealthcare.ahrq.gov/sites/default/files/adhd_disposition-comments.pdf
    October 01, 2011 - These questions have been derived through AHRQ procedure and cannot be changed Peer Reviewer #4 … in order to conduct the review at all, but “because I said so” is not exactly a strong, scientific method … Peer Reviewer #3 Methods Overall, the method section did a good job in describing how studies were … Single studies with contrary findings raise questions about the method that merit explication and caution … subsequent to PR version Peer Reviewer #7 Results p 127 L-20 Treated prevalence –more specific than method
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
    November 30, 2014 - biocompatible tissue-bulking agents into the anal canal walls are a newer, more invasive nonsurgical procedure … .11 Surgical procedures used to treat FI in the United States include implanted sacral nerve stimulators … etc.) and become progressively more invasive (local injections of tissue-bulking material, surgical proceduresMethods A. … If dissimilar baseline Yes What method?
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
    April 03, 2013 - psychodynamic approaches, and a farewell ritual at the end of the treatment in a single treatment method … The clinician follows standardized procedures to monitor and guide the patient’s associative process … Eye movement desensitization and reprocessing: Basic principles, protocols and procedures (2nd ed.). … is a primary author in the study of that method. … This tends to be a limitation of the AHRQ/GRADE method and not this document, per se.
  14. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - Please see the methods section for more details about this process. … interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests, procedures … identifying new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Executive Summary Background Methods Results Discussion
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
    August 06, 2018 - Studies that do not report their methods sufficiently may be rated as unclear risk of bias. … Methods Guide for Effectiveness and Comparative Effectiveness Reviews. … Comparative Effectiveness Review Methods: Clinical Heterogeneity Methods Research Report. … "[MeSH] OR "Double- Blind Method"[MeSH] OR "Random Allocation"[MeSH]) 716633 #19 Search (#14 and … Methods V. References VI. Definition of Terms VII. Summary of Protocol Amendments VIII.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-vibration-therapy_disposition-comments.pdf
    November 15, 2011 - We make this exclusion clearer in the methods section. … There are standardized methods to assess the risk of bias, e.g., JADAD, PEDro. … Peer Reviewer #2 Methods p. 3 l44-46: There is a problem with the appendices. … In this method, the low levels of vibration displacements were optimally designed using simulation studies … The effective stress on the bone by this method is the combined stress on the bone from low-level vibration
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-presentation-format_research.pdf
    January 01, 2019 - Methods Future Research Needs Report No. 3. … We welcome comments on this Methods Research Project. … to inform prioritization of future research, but all agreed that modeling should not be the only method … cost-benefit analysis 2008 BMJ 17638858 Diagnostic accuracy and clinical utility of a simplified low cost method … alternatives for beef bulls with preputial prolapse 1997 J Am Vet Med Assoc 9357709 A decision analytic method
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
    February 15, 2018 - Peer Reviewer 1 Methods 2. … Peer Reviewer 1 Methods 4. … Peer Reviewer 1 Methods 5. … , in the Methods section. … TEP Reviewer 4 Methods In the search strategy (Methods Search Strategy, Page 14 of 173), I would
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
    September 19, 2014 - Methods The methods for this Comparative Effectiveness Review (CER) follow the methods suggested in … Effectiveness Reviews.30 All methods were determined a priori. … Methods Guide for Effectiveness and Comparative Effectiveness Reviews. … Preventive Services Task Force Procedure Manual. … Methods Guide for Medical Test Reviews.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
    August 09, 2013 - Other procedures and imaging tests are also used to aid diagnosis of pancreatic adenocarcinoma, including … Also, procedural harms of the imaging procedures may occur. IV. Methods A. … We will include any reported data on more than 100 patients on the harms of imaging procedures from … harm or reporting that no harms or complications occurred as a result of the procedure. … Was the method of study quality assessment consistent with that recommended by the Methods Guide?

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