-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-value-of-information_research.pdf
June 01, 2011 - In other cases, a factor is considered, but without much
rigorous analysis. … The use of VOI analysis is advocated in published methods
27guidance. … (long term)
modeled using
DEALE method
Life-years gained
modeled using
pooled estimates
from meta-analysis … Net health benefits:
a new framework for the analysis of
uncertainty in cost-effectiveness analysis … for methods to perform
sensitivity analysis and the use of cost-
effectiveness analysis to set priorities
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-vibration-therapy_disposition-comments.pdf
November 15, 2011 - Reviewer #1 Summary
and
Implications
Regarding impact of compliance, please refer to the sub-group analysis … noted that one of the cited articles, in
the draft technical brief, which was a systematic review and meta … -
analysis of randomized controlled trials about whole-body vibration,
concludes that “before recommendations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_disposition-comments.pdf
May 01, 2013 - ES-7 and pgs.
17-18) includes a detailed description of meta-
analysis and other quantitative models … In at least two places the team states
that meta-analysis was not possible. … Not clear if the diagnostic test
properties which were used for the simulation were
meta-estimates … would be able to combine literature identified in
that report with newer data in any subsequent
meta-analyses … models are an alternative method for
quantitatively synthesizing the literature,
analogous to a meta-analysis—the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-roadmap-interventions.pdf
November 01, 2020 - cognitive behavioral
therapy and pharmacotherapy for childhood
anxiety disorders: a systematic review and meta … -
analysis. … Improving the interpretation of quality of life
evidence in meta-analyses: the application of
minimal
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_disposition-comments.pdf
January 01, 2010 - and
manufacturing companies to reduce the of risk bias from not including
gray literature in the analysis … is the accepted primary method of statistical
analysis for evaluation of a clinical trial. … An
acceptable alternative in some regulatory circles
is the Per-Protocol (PP) analysis. … Our review did not do any further subgroup
analysis. … limitations
are well described and closely mirror the
limitations of prior systematic reviews and meta
-
effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
October 01, 2007 - problems with evi-
dence from evidence-based medicine (EBM), whose
main tools are randomized trials and meta-analysis … effect of a new or existing treatment will be
revealed by the study, and to provide a confirmatory analysis … the Clinical Practice Team using bivariate
and multivariable analyses, including multiple regression,
analysis … include condition-specific physiologic data such as those in
the CSI.5,14–20 The CSI is used in data analysis … the study
patients are involved in study design, defining study vari-
ables, study execution, data analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
September 01, 2010 - breast
cancer
Actively recruit minorities to gather
sufficient power in ongoing studies
P
Meta-analysis … most likely to benefit from
medications to reduce the risk of breast
cancer
111 109, 112 113
Meta-analysis … Differential effects of MDM2 SNP309
polymorphism on breast cancer risk along
with race: a meta-analysis … XRCC1 gene
polymorphisms and breast cancer risk in
different populations: a meta-analysis. … Green
tea consumption and breast cancer risk or
recurrence: a meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
November 01, 2010 - However, based on a meta-
analysis examining the longitudinal association of reduced estimated GFR and … albuminuria with all-cause and cardiovascular mortality
in general population cohorts: a collaborative meta-analysis … The TEP does not do analysis of any kind nor contribute to the writing of
the report.
X.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-200-comments-post-acs.pdf
November 14, 2017 - including those
published before 2005, to provide more data for
instrument comparison as a secondary analysis … TEP #6 Methods 4) The statistical analysis including assessment of study
quality and strength of evidence … Reviewer #3
Methods p.13, the requirement that at least 3 studies should be
available to do a meta-analysis … The reviewer is correct that the
minimal number of studies for a
meta-analysis can be based on
power … TEP #6 Results 2) Yes, study characteristics including bias analysis,
strength of evidence are appropriately
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-pharm-non-pharm-treatment-update-disposition-comments.pdf
August 28, 2024 - #1
Results The result section is surprisingly long and detailed
despite the fact that there is no analysis … categories, this type
of comparing and
combining effect size
data more nimbly
than conducting a
meta-analysis … Statistical analysis was appropriate based
on my limited knowledge.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-adherence-interventions_executive.pdf
September 01, 2012 - population, intervention,
comparator, outcome), we considered conducting
quantitative analyses (i.e., meta-analysis … Because quantitative analysis was not
appropriate (due, for example, to heterogeneity, insufficient … Meta-analysis of trials of
interventions to improve medication adherence. … Patient
adherence and medical treatment outcomes: a meta-analysis. … Closing the Quality Gap: A Critical Analysis of Quality
Improvement Strategies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - Tamoxifen and raloxifene did not significantly
reduce noninvasive breast cancer, including DCIS,
in meta-analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-treatment_executive.pdf
May 01, 2011 - A poor-quality study
contained a serious flaw in design, analysis, or execution,
such as differential … Meta-analyses
were always conducted within groups because of the high
degree of clinical and methodological … We used Stata 11.2® for all effect size calculations
and meta-analyses (Stata Corp., College Station … during protocol development, rigorous
adherence to inclusion/exclusion rules, and conservative
use of meta-analysis … Statistical power analysis for the behavioral sciences.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
December 01, 2010 - The reports are
based on rigorous, comprehensive syntheses (systematic reviews) and analyses (meta-analyses … Systematic
reviews in health care: meta-analysis in context.
London: BMJ; 2001. p. 23-42.
3. … Systematic reviews in health care: meta-analysis
in context. London: BMJ; 2001:211-227.
10. … Evidence
Analysis Manual: Steps in the ADA Evidence
Analysis Process. 2009.
50. … The effects of psychological therapies under
clinically representative conditions: a meta-
analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
March 01, 2009 - A meta-analysis. Thromb Haemost
2008;99(2):338-342. Review/No data
7. … Risk of ischemic stroke with tamoxifen treatment for breast
cancer: a meta-analysis. … Alcohol intake and risk of breast cancer defined by
estrogen and progesterone receptor status—a meta-analysis … surrounding an effect
estimate with respect to a given outcome (i.e., for each
outcome separately)
If a meta-analysis … Intention-to-
treat analysis?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-prognostic-tests_research.pdf
August 22, 2012 - A recent meta-analysis found ER+ DCIS
to be associated with significantly lower
IBTR rates, while HER2 … Since SEER registries also collect informa-
tion about ER and PR testing, we con-
ducted a sensitivity analysis … The results of this analysis showed that
our claims-based measure was, although
slightly lower, close … Two key messages emerged from analysis
of ER positivity: first, rates of positivity
were almost identical … breast cancer
hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-
level meta-analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bariatric-surgery_research.pdf
June 01, 2010 - All listed authors contributed to the design, analysis, or writing of
this study. … Pre-post analysis. … Bariatric surgery: a systematic review and meta-
analysis. JAMA 2004;292(14):1724-1737.
3. … Longitudinal data analysis
for discrete and continuous outcomes. … An analysis of health insurance data.
Int J Obes Relat Metab Disord 1996;20:820-824.
C2.
-
effectivehealthcare.ahrq.gov/sites/default/files/home-based-care_disposition-comments.pdf
February 16, 2016 - Good quality study with
instrumental variable analysis for ACS hospitalizations. … Statistical methods were used
and briefly described in Appendix A, but the results were not
provided (meta-analysis … to provide estimates on outcomes;
meta-regression to explore statistical heterogeneity). … Upon fully reviewing the diverse data
reported in the studies we were unable
to conduct a meta-analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
January 01, 2023 - Spray vs Typical
Oral Long-Acting Opioid Analgesics in
Patients with Severe Neuropathic Back Pain:
Analysis … Cannabinoids for medical use: a systematic
review and meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-pain-management-grand-rounds-slides.pptx
March 01, 2022 - recommendation will conform to the generally accepted standards of experimental design, data collection, and analysis … official views of or imply endorsement by AHRQ or HHS.
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Key Questions
Systematic review and meta-analysis