-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-sepsis.pdf
July 01, 2023 - We will
not conduct a meta-analysis. … Analysis of Subgroups or Subsets
We will report if the effectiveness of the PSP differs across patient … Making Healthcare Safer III: A Critical Analysis of
Existing and Emerging Patient Safety Practices.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
January 01, 2024 - We will
not conduct a meta-analysis. … Analysis of Subgroups or Subsets
We will report if the effectiveness of the PSP differs across patient … Data Extraction
Risk of Bias Assessment
Data Synthesis
Analysis of Subgroups or Subsets
Registration
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/prehospital-airway-management-protocol.pdf
December 20, 2019 - They have a serious or “fatal” flaw (or combination of flaws) in design, analysis, or
reporting; large … Meta-analyses will be conducted
using a random effects model. … If warranted, we will conduct sensitivity analyses by repeating
meta-analyses with and without selected … Technical Experts do not do analysis of
any kind nor do they contribute to the writing of the report … (comment or editorial or meta-analysis or practice-guideline or review or letter).pt.
25. (21 or 22
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
March 13, 2012 - Was a reclassification analysis performed with risk stratification using GEP when
compared with that … (It is suggested that samples from at least two-thirds of the patients
must be available for analysis … • Was MSI (MMR) status considered in the overall analysis?
o If so, how? … • Was the GEP performed (analysis, calculation, interpretation) as described in
initial studies for … expression profiles as predictors of poor
outcomes in stage II colorectal cancer: a systematic review and meta-analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
January 01, 2013 - Limitations
Because only cases with discrepant exposure history contribute information to the analysis … The new-user design offers a further advantage in anchoring the time scale for analysis at time since … A meta-analysis of the association between adherence to drug therapy and mortality. … Biases introduced by suboptimal study design cannot usually be removed by statistical analysis. … Biases introduced by suboptimal study design cannot usually be removed during the statistical analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
December 05, 2018 - (i.e., meta-analysis) of the data from those
studies. … We will also consider conducting network meta-analysis using Bayesian methods to
compare the interventions … under consideration following established guidance.44
If we conduct quantitative syntheses (i.e., meta-analysis … The effects of postpartum depression on maternal-infant interaction: A meta-
analysis. … reuptake inhibitor (SSRI) use
during pregnancy and risk of preterm birth: a systematic review and meta-analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
February 01, 2012 - chemoradiotherapy,
immunosuppressive therapy, and supportive care), and
outcomes and details of any data analysis … Systematic Review Data Synthesis and Analysis
Data synthesis was qualitative. … Systematic Review Results
Figure D shows a PRISMA (Preferred Reporting Items
of Systematic reviews and Meta-Analyses … ; IMD = inherited metabolic diseases; PRISMA = Preferred
Reporting Items of Systematic reviews and Meta-Analyses
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
February 25, 2014 - Agreed, this is distracting so we
removed the 5-ASA meta-
analysis, especially given that the
largest … study in the meta-analysis
was for olsalazine, which is not
used in practice
Peer Reviewer-1 Results … Additionally,
we were not able to perform a
meta-analysis at the later time
points because of design … See meta-analysis by Kandiel for
association of thiopurine therapy for IBD with lymphoma. … We have removed the pooled
relative risk from the Key Points
and removed the meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tech-brief-31-mobile-applications-self-mgmt.pdf
May 01, 2018 - A
systematic review, meta-analysis, and GRADE
of 14 randomized trials. … T2DM Self-
Management via Smartphone Applications: A
Systematic Review and Meta-Analysis. … ((comprehensive* or integrative or systematic*) adj3 (bibliographic* or review* or literature)) or (meta … Report: Technology Assessment*.jn. or ((review adj5 (rationale or
evidence)).ti,ab. and review.pt.) or meta-analysis … as topic/ or Meta-Analysis.pt.
12 and/10-11
13 (201709* or 201710* or 201711* or 201712*).dc.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-genetic_methods.pdf
July 01, 2012 - Epidemiology Network (HuGE Net) Web site can provide a helpful
supplement to searches, as it includes many meta-analyses … types of samples, the specific analyte investigated, specific genotyping
methods, timing of sample analysis … How were samples handled and stored prior to analysis?
Analytic What type of assay was used? … Was the timing of analysis equal for both study groups (if applicable)? … Repeated replication and a prospective meta-
analysis of the association between
chromosome 9p21.3 and
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_executive.pdf
May 01, 2014 - An analysis of Medicare
claims data for 2007–09 reported that 35.2 percent of
readmissions within 30 … To address these
issues, we conducted a systematic review and meta-
analysis of investigations of transitional … When we
combined multiple scales in one meta-analysis, we used
the standardized mean difference, Cohen … Future research
could also include methods such as meta-analysis of individual
patient data to ascertain … Quantifying heterogeneity in a meta-
analysis. Stat Med. 2002 Jun 15;21(11):1539-58.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/screening-counseling-interventions-protocol.pdf
October 01, 2023 - If we find three or
more similar RCTs addressing an outcome of interest, we will consider meta-
analysis … For all meta-analyses, we will use random
effects models to estimate pooled effects. … To leverage the expected heterogeneity, we will use the Qualitative
Comparative Analysis (QCA) to identify … Identification of
preschool children with mental health
problems in primary care: systematic
review and meta-analysis … Technical Experts do not perform analysis of any kind; neither do
they contribute to the writing of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_disposition-comments.pdf
July 01, 2012 - As an example, cumulative
meta-analyses of thrombolysis for MI have shown a consistent benefit
over … pre-selected prognostic variables, and (5) any
within trial baseline differences are even less important in a meta-analysis … COPD, pulmonary
edema, etc) either in a trial-level meta-regression or a stratified analysis? … -
analysis. … The study by Agarwal is a meta-analysis, and its
bibliography was reviewed for relevant citations.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_disposition-comments.pdf
May 29, 2013 - heterogeneous, the authors
may consider referring to them as systematic reviews
as opposed to true meta-analytic … Somewhat
surprisingly, the authors do not include meta-analyses
of the genetic impact upon clopidogrel … All these studies
were observational cohorts and could not be combined
with the RCTs in the network meta-analysis … walking distance (figure D) the conclusion
that cilostazol had no benefit is counter to the
published meta … Again, statements, such as,
“Meta-analysis of endovascular versus surgical
revascularization studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - Data will be qualitatively summarized in tables, using ranges and descriptive analysis
and interpretation … cannabinoids for the treatment of people with
chronic noncancer pain conditions: a systematic review and meta-analysis … Cannabinoids for Medical Use: A Systematic Review and
Meta-analysis. … Statistical methods for updating
meta-analyses. … Technical Experts do not do analysis of any kind nor do
they contribute to the writing of the report
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
March 15, 2010 - require input from
domain experts to assess whether studies are too clinically heterogeneous for a meta-analysis … We will perform only random effects model meta-analyses. … We will not attempt any meta-regression of these studies. … If data are
available, we will consider sub-group meta-analyses based on the findings of these studies … The TEP does not do analysis of any kind
nor contribute to the writing of the report.
X.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
September 01, 2009 - The DerSimonian and Laird approach was used for all
meta-analyses, except for rare events (less than … Substantial heterogeneity
precluded statistical analysis of 18 statin-ezetimibe and
4 statin-BAS trials … statin-ezetimibe combination
therapy were noted in all 10 trials, with substantial
heterogeneity precluding meta-analysis … Meta-analysis of two statin-fibrate trials demonstrated
no significant difference between treatments … All trials must clearly report adequate allocation
concealment and intention-to-treat analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
April 20, 2022 - evaluate studies that
directly compare alternative regimens but will also attempt to conduct network meta-analysis … citations of 0.40
(this threshold is based on experience with several dozen screening projects and an analysis … groups) and relevant concepts addressed
for RCTs (i.e., related to missing data, outcome measurement, analysis … Technical Experts provide further input to finalize the KQs, study eligibility criteria, and
analysis … Technical Experts do not do analysis of any kind;
neither do they contribute to the writing of the report
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
June 01, 2018 - outcomes reported
no effect on all-cause mortality.15
Graudal and colleagues (2014) conducted a meta-analysis … Effect of lower sodium
intake on health: systematic review and meta-analyses. … Effect of lower sodium
intake on health: systematic review and meta-analyses. … Blood pressure lowering
for prevention of cardiovascular disease and death: a systematic
review and meta-analysis … with usual
sodium intake, low- and excessive-sodium diets are associated
with increased mortality: a meta-analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
October 05, 2015 - Systematic reviews, with or without meta-analyses
•! … studies for a comparison of
interest), we will augment findings with quantitative analyses (i.e., meta-analysis … If we conduct
quantitative syntheses (i.e., meta-analysis), we will assess statistical heterogeneity … We will also examine potential sources of
heterogeneity using sensitivity analysis or analysis of subgroups … Technical Experts do not do analysis of any kind nor do
they contribute to the writing of the report