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Showing results for "meta analysis".

901. Understanding Health-Systems’ Use of and Need for Evidence To Inform Decisionmaking (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-systems-research.pdf
     October 01, 2017 - …meta-analysis frequently contain a potpourri of trials that may or may not necessarily be timely or … The meta-analysis does have some utility but as I'm sure you know to collect a dozen trials, to do … a meta-analysis, some of those trials included may be five, six, seven, eight years older, and so they … This is important in root cause analysis. … Then they go into root cause analysis, that is where education begins.

902. Making Healthcare Safer IV: Programs for Responding to Harms Experienced by Patients during Clinical Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/clinical-care-protocol.pdf
     January 01, 2024 - interview patients and families, who are willing and able, to gather evidence for the root cause analysis … take to prevent future reoccurrences of similar events based on the findings from the root cause analysis … We will not conduct a meta-analysis. … Analysis of Subgroups or Subsets We will assess whether the effectiveness of programs differs according … Data Extraction Risk of Bias Assessment Data Synthesis Analysis of Subgroups or Subsets Registration

903. Noninvasive Treatments for Low Back Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
     February 01, 2016 - We did not conduct updated meta-analysis with new studies. … The effect of antidepressant treatment on chronic back pain: a meta-analysis. … Sling exercise for chronic low back pain: a systematic review and meta-analysis. … Walking exercise for chronic musculoskeletal pain: systematic review and meta-analysis. … Effectiveness of self-management of low back pain: systematic review with meta- analysis.

904. Disposition of Comments for Treatment Strategies for Patients With Peripheral Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_disposition-comments.pdf
     May 29, 2013 - heterogeneous, the authors may consider referring to them as systematic reviews as opposed to true meta-analytic … Somewhat surprisingly, the authors do not include meta-analyses of the genetic impact upon clopidogrel … All these studies were observational cohorts and could not be combined with the RCTs in the network meta-analysis … walking distance (figure D) the conclusion that cilostazol had no benefit is counter to the published meta … Again, statements, such as, “Meta-analysis of endovascular versus surgical revascularization studies

905. Evidence-based Practice Center Systematic Review Protocol: Prehospital Airway Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prehospital-airway-management-protocol.pdf
     December 20, 2019 - They have a serious or “fatal” flaw (or combination of flaws) in design, analysis, or reporting; large … Meta-analyses will be conducted using a random effects model. … If warranted, we will conduct sensitivity analyses by repeating meta-analyses with and without selected … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report … (comment or editorial or meta-analysis or practice-guideline or review or letter).pt. 25. (21 or 22

906. Vte-Prophyalaxis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
     May 01, 2013 - For studies amenable to pooling quantitatively, we conducted meta- analysis using relative risks by … designs • Time-series designs • No original data, commentary, or editorial • Systematic reviews and meta-analysis … not specified at the start of the trial, so that this information is available to researchers doing meta … Meta-analysis in clinical trials. Control Clin Trials 1986; 7(3):177-88. 33. … Use and avoidance of continuity corrections in meta-analysis of sparse data.

907. Tinnitus Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
     August 01, 2013 - Meta-analysis was not undertaken due to the clinical heterogeneity of the interventions and outcomes … The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-Analyses … biloba does not benefit patients with tinnitus: a randomized placebo-controlled double- blind trial and meta-analysis … Systematic review and meta-analyses of randomized controlled trials examining tinnitus management.

908. Maternal and Fetal Effects of Mental Health Treatments in Pregnant and Breastfeeding Women: A Systematic Review of Pharmacological Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
     December 05, 2018 - (i.e., meta-analysis) of the data from those studies. … We will also consider conducting network meta-analysis using Bayesian methods to compare the interventions … under consideration following established guidance.44 If we conduct quantitative syntheses (i.e., meta-analysis … The effects of postpartum depression on maternal-infant interaction: A meta- analysis. … reuptake inhibitor (SSRI) use during pregnancy and risk of preterm birth: a systematic review and meta-analysis

909. Disposition of Comments Report for Comparative Effectiveness Review No. 131 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
     February 25, 2014 - Agreed, this is distracting so we removed the 5-ASA meta- analysis, especially given that the largest … study in the meta-analysis was for olsalazine, which is not used in practice Peer Reviewer-1 Results … Additionally, we were not able to perform a meta-analysis at the later time points because of design … See meta-analysis by Kandiel for association of thiopurine therapy for IBD with lymphoma. … We have removed the pooled relative risk from the Key Points and removed the meta-analysis.

910. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - Meta-analysis was deemed infeasible because of the wide variety of comparisons, outcomes, and measures … Systematic reviews and subsequent meta-analyses are meant to facilitate an evaluation of the totality … RCTs (including healthy adults and MCI, excluding non-randomized trials, case studies, reviews, and meta-analyses … We could not perform meta-analyses because the cognitive measures were too diverse; they did not even … Since we included only low or medium risk of bias studies in the analysis, the analysis is by default

911. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - Meta-analysis was deemed infeasible because of the wide variety of comparisons, outcomes, and measures … Systematic reviews and subsequent meta-analyses are meant to facilitate an evaluation of the totality … RCTs (including healthy adults and MCI, excluding non-randomized trials, case studies, reviews, and meta-analyses … We could not perform meta-analyses because the cognitive measures were too diverse; they did not even … Since we included only low or medium risk of bias studies in the analysis, the analysis is by default

912. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
     September 29, 2014 - authors to set a minimum duration of observation of 1 year as a criterion for study inclusion in the meta-analysis … After the extensive review and analysis the actual contribution to practice and policy is limited as … The statistical methods also seem appropriate in that no meta-analyses could be performed based on … Due to the paucity of data, meta-analytic methods were not used which is appropriate. … Long-term opioid therapy for chronic non-cancer pain: A systematic review and meta-analysis of efficacy

913. Making Healthcare Safer IV Rapid Response_Active Surveillance Culturing of Clostridioides difficile and Multidrug-Resistant Organisms: Methicillin-Resistant Staphylococcus aureus, Carbapenem-Resistant Enterobacterales, and Candida auris (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
     May 01, 2024 - In a 2016 meta-analysis, CRE colonized patients had a 16.5 percent cumulative infection rate.30 In … toxinogenic C. difficile upon hospital admission, and risk of infection: a systematic review and meta-analysis … MycoSNP: A portable workflow for performing whole-genome sequencing analysis of candida auris. … preoperative screening and decolonization for staphylococcus aureus in total joint arthroplasty: A meta-analysis … A systematic review and meta-analysis.

914. Implementation of Recommended Screening and Counseling Interventions to Prevent Mental Health Disorders in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/screening-counseling-interventions-protocol.pdf
     October 01, 2023 - If we find three or more similar RCTs addressing an outcome of interest, we will consider meta- analysis … For all meta-analyses, we will use random effects models to estimate pooled effects. … To leverage the expected heterogeneity, we will use the Qualitative Comparative Analysis (QCA) to identify … Identification of preschool children with mental health problems in primary care: systematic review and meta-analysis … Technical Experts do not perform analysis of any kind; neither do they contribute to the writing of

915. Living Systematic Review on Plant-Based Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
     March 29, 2023 - Data will be qualitatively summarized in tables, using ranges and descriptive analysis and interpretation … cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis … Cannabinoids for Medical Use: A Systematic Review and Meta-analysis. … Statistical methods for updating meta-analyses. … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report

916. Evidence-Summary-CER-206-Sodium-And-Potassium-Intake-Effects-On-Chronic-Disease-Outcomes-And-Risk (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
     June 01, 2018 - outcomes reported no effect on all-cause mortality.15 Graudal and colleagues (2014) conducted a meta-analysis … Effect of lower sodium intake on health: systematic review and meta-analyses. … Effect of lower sodium intake on health: systematic review and meta-analyses. … Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis … with usual sodium intake, low- and excessive-sodium diets are associated with increased mortality: a meta-analysis

917. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
     March 15, 2010 - require input from domain experts to assess whether studies are too clinically heterogeneous for a meta-analysis … We will perform only random effects model meta-analyses. … We will not attempt any meta-regression of these studies. … If data are available, we will consider sub-group meta-analyses based on the findings of these studies … The TEP does not do analysis of any kind nor contribute to the writing of the report. X.

918. A Systematic Review of Postpartum Home Blood Pressure Monitoring, Postpartum Treatment of Hypertensive Disorders of Pregnancy, and Peripartum Magnesium Sulfate Regimens for Preeclampsia With Severe Features (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
     April 20, 2022 - evaluate studies that directly compare alternative regimens but will also attempt to conduct network meta-analysis … citations of 0.40 (this threshold is based on experience with several dozen screening projects and an analysis … groups) and relevant concepts addressed for RCTs (i.e., related to missing data, outcome measurement, analysis … Technical Experts provide further input to finalize the KQs, study eligibility criteria, and analysis … Technical Experts do not do analysis of any kind; neither do they contribute to the writing of the report

919. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
     September 01, 2009 - The DerSimonian and Laird approach was used for all meta-analyses, except for rare events (less than … Substantial heterogeneity precluded statistical analysis of 18 statin-ezetimibe and 4 statin-BAS trials … statin-ezetimibe combination therapy were noted in all 10 trials, with substantial heterogeneity precluding meta-analysis … Meta-analysis of two statin-fibrate trials demonstrated no significant difference between treatments … All trials must clearly report adequate allocation concealment and intention-to-treat analysis.

920. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
     October 05, 2015 - Systematic reviews, with or without meta-analyses •! … studies for a comparison of interest), we will augment findings with quantitative analyses (i.e., meta-analysis … If we conduct quantitative syntheses (i.e., meta-analysis), we will assess statistical heterogeneity … We will also examine potential sources of heterogeneity using sensitivity analysis or analysis of subgroups … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report