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Showing results for "meta analysis".

901. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - Meta-analysis was deemed infeasible because of the wide variety of comparisons, outcomes, and measures … Systematic reviews and subsequent meta-analyses are meant to facilitate an evaluation of the totality … RCTs (including healthy adults and MCI, excluding non-randomized trials, case studies, reviews, and meta-analyses … We could not perform meta-analyses because the cognitive measures were too diverse; they did not even … Since we included only low or medium risk of bias studies in the analysis, the analysis is by default

902. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - Meta-analysis was deemed infeasible because of the wide variety of comparisons, outcomes, and measures … Systematic reviews and subsequent meta-analyses are meant to facilitate an evaluation of the totality … RCTs (including healthy adults and MCI, excluding non-randomized trials, case studies, reviews, and meta-analyses … We could not perform meta-analyses because the cognitive measures were too diverse; they did not even … Since we included only low or medium risk of bias studies in the analysis, the analysis is by default

903. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
     September 29, 2014 - authors to set a minimum duration of observation of 1 year as a criterion for study inclusion in the meta-analysis … After the extensive review and analysis the actual contribution to practice and policy is limited as … The statistical methods also seem appropriate in that no meta-analyses could be performed based on … Due to the paucity of data, meta-analytic methods were not used which is appropriate. … Long-term opioid therapy for chronic non-cancer pain: A systematic review and meta-analysis of efficacy

904. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-safety-practices_research-protocol.pdf
     November 09, 2011 - November 9, 2011 Evidence-based Practice Center Systematic Review Protocol Project Title: Critical Analysis … Background and Objectives for the Systematic Review The critical systematic review and analysis of … The analysis will assess the evidence of the effectiveness of new safe practices and the adoption of … restraints  Diagnostic errors – meta cognition, computerized decision support  Protocols for notification … on the effectiveness of intervention and implementation  Data synthesis will be narrative or meta-analytic

905. hemorrhage-postpartum-protocol-140611 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
     June 11, 2014 - If meta-analysis is done, then studies with an N smaller than 42 could be combined. … that some studies may be included for initial consideration and later found not to be useable in a meta-analysis … results We anticipate variations in the populations and interventions studied that may preclude meta-analysis … Identifying regional variation in the prevalence of postpartum haemorrhage: a systematic review and meta-analysis … Misoprostol to prevent and treat postpartum haemorrhage: a systematic review and meta-analysis of maternal

906. Renal-Artery-Stenosis Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
     June 01, 2012 - CERs with no meta-analysis were examined for qualitative signals only. … For any CER that contains meta-analysis(es), we first assess for the qualitative signal(s), and if no … These signals, except for one (A7), specify findings from a pivotal trial, meta-analysis (with at least … ., to new subgroups of subjects) – A5 • Clinically important caveat – A6 • Opposing findings from meta-analysis … (in relation to a meta-analysis in the original CER) or non-pivotal trial – A7 * Please

907. Noninvasive Treatments for Low Back Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
     February 01, 2016 - We did not conduct updated meta-analysis with new studies. … The effect of antidepressant treatment on chronic back pain: a meta-analysis. … Sling exercise for chronic low back pain: a systematic review and meta-analysis. … Walking exercise for chronic musculoskeletal pain: systematic review and meta-analysis. … Effectiveness of self-management of low back pain: systematic review with meta- analysis.

908. Evidence-based Practice Center Systematic Review Protocol: Prehospital Airway Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prehospital-airway-management-protocol.pdf
     December 20, 2019 - They have a serious or “fatal” flaw (or combination of flaws) in design, analysis, or reporting; large … Meta-analyses will be conducted using a random effects model. … If warranted, we will conduct sensitivity analyses by repeating meta-analyses with and without selected … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report … (comment or editorial or meta-analysis or practice-guideline or review or letter).pt. 25. (21 or 22

909. Maternal and Fetal Effects of Mental Health Treatments in Pregnant and Breastfeeding Women: A Systematic Review of Pharmacological Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
     December 05, 2018 - (i.e., meta-analysis) of the data from those studies. … We will also consider conducting network meta-analysis using Bayesian methods to compare the interventions … under consideration following established guidance.44 If we conduct quantitative syntheses (i.e., meta-analysis … The effects of postpartum depression on maternal-infant interaction: A meta- analysis. … reuptake inhibitor (SSRI) use during pregnancy and risk of preterm birth: a systematic review and meta-analysis

910. Disposition of Comments Report for Comparative Effectiveness Review No. 131 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
     February 25, 2014 - Agreed, this is distracting so we removed the 5-ASA meta- analysis, especially given that the largest … study in the meta-analysis was for olsalazine, which is not used in practice Peer Reviewer-1 Results … Additionally, we were not able to perform a meta-analysis at the later time points because of design … See meta-analysis by Kandiel for association of thiopurine therapy for IBD with lymphoma. … We have removed the pooled relative risk from the Key Points and removed the meta-analysis.

911. Heart-Failure-Transition-Care Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_executive.pdf
     May 01, 2014 - An analysis of Medicare claims data for 2007–09 reported that 35.2 percent of readmissions within 30 … To address these issues, we conducted a systematic review and meta- analysis of investigations of transitional … When we combined multiple scales in one meta-analysis, we used the standardized mean difference, Cohen … Future research could also include methods such as meta-analysis of individual patient data to ascertain … Quantifying heterogeneity in a meta- analysis. Stat Med. 2002 Jun 15;21(11):1539-58.

912. Implementation of Recommended Screening and Counseling Interventions to Prevent Mental Health Disorders in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/screening-counseling-interventions-protocol.pdf
     October 01, 2023 - If we find three or more similar RCTs addressing an outcome of interest, we will consider meta- analysis … For all meta-analyses, we will use random effects models to estimate pooled effects. … To leverage the expected heterogeneity, we will use the Qualitative Comparative Analysis (QCA) to identify … Identification of preschool children with mental health problems in primary care: systematic review and meta-analysis … Technical Experts do not perform analysis of any kind; neither do they contribute to the writing of

913. Disposition of Comments Report for Comparative Effectiveness Review #68 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_disposition-comments.pdf
     July 01, 2012 - As an example, cumulative meta-analyses of thrombolysis for MI have shown a consistent benefit over … pre-selected prognostic variables, and (5) any within trial baseline differences are even less important in a meta-analysis … COPD, pulmonary edema, etc) either in a trial-level meta-regression or a stratified analysis? … - analysis. … The study by Agarwal is a meta-analysis, and its bibliography was reviewed for relevant citations.

914. Disposition of Comments for Treatment Strategies for Patients With Peripheral Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_disposition-comments.pdf
     May 29, 2013 - heterogeneous, the authors may consider referring to them as systematic reviews as opposed to true meta-analytic … Somewhat surprisingly, the authors do not include meta-analyses of the genetic impact upon clopidogrel … All these studies were observational cohorts and could not be combined with the RCTs in the network meta-analysis … walking distance (figure D) the conclusion that cilostazol had no benefit is counter to the published meta … Again, statements, such as, “Meta-analysis of endovascular versus surgical revascularization studies

915. Living Systematic Review on Plant-Based Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
     March 29, 2023 - Data will be qualitatively summarized in tables, using ranges and descriptive analysis and interpretation … cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis … Cannabinoids for Medical Use: A Systematic Review and Meta-analysis. … Statistical methods for updating meta-analyses. … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report

916. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
     March 15, 2010 - require input from domain experts to assess whether studies are too clinically heterogeneous for a meta-analysis … We will perform only random effects model meta-analyses. … We will not attempt any meta-regression of these studies. … If data are available, we will consider sub-group meta-analyses based on the findings of these studies … The TEP does not do analysis of any kind nor contribute to the writing of the report. X.

917. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
     September 01, 2009 - The DerSimonian and Laird approach was used for all meta-analyses, except for rare events (less than … Substantial heterogeneity precluded statistical analysis of 18 statin-ezetimibe and 4 statin-BAS trials … statin-ezetimibe combination therapy were noted in all 10 trials, with substantial heterogeneity precluding meta-analysis … Meta-analysis of two statin-fibrate trials demonstrated no significant difference between treatments … All trials must clearly report adequate allocation concealment and intention-to-treat analysis.

918. A Systematic Review of Postpartum Home Blood Pressure Monitoring, Postpartum Treatment of Hypertensive Disorders of Pregnancy, and Peripartum Magnesium Sulfate Regimens for Preeclampsia With Severe Features (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
     April 20, 2022 - evaluate studies that directly compare alternative regimens but will also attempt to conduct network meta-analysis … citations of 0.40 (this threshold is based on experience with several dozen screening projects and an analysis … groups) and relevant concepts addressed for RCTs (i.e., related to missing data, outcome measurement, analysis … Technical Experts provide further input to finalize the KQs, study eligibility criteria, and analysis … Technical Experts do not do analysis of any kind; neither do they contribute to the writing of the report

919. Evidence-Summary-CER-206-Sodium-And-Potassium-Intake-Effects-On-Chronic-Disease-Outcomes-And-Risk (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
     June 01, 2018 - outcomes reported no effect on all-cause mortality.15 Graudal and colleagues (2014) conducted a meta-analysis … Effect of lower sodium intake on health: systematic review and meta-analyses. … Effect of lower sodium intake on health: systematic review and meta-analyses. … Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis … with usual sodium intake, low- and excessive-sodium diets are associated with increased mortality: a meta-analysis

920. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
     October 05, 2015 - Systematic reviews, with or without meta-analyses •! … studies for a comparison of interest), we will augment findings with quantitative analyses (i.e., meta-analysis … If we conduct quantitative syntheses (i.e., meta-analysis), we will assess statistical heterogeneity … We will also examine potential sources of heterogeneity using sensitivity analysis or analysis of subgroups … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report