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effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
May 19, 2020 - We will develop a search
strategy for PubMed, based on an analysis of the medical subject headings ( … determine if they should be included in the final qualitative and quantitative
systematic review and meta-analysis … as conduct a meta-regression
analysis if covariate information (e.g., age, sex) is available. … For sparse data meta-analysis, we will employ the Peto Odds ratio method when
event rates are less than … Statistical power analysis for the behavioral sciences. Hillsdale, NJ: L.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_disposition-comments.pdf
March 01, 2012 - Was
meta-analysis of subgroup data, estimates of association, or
meta-regression not possible? … that it is
also possible to tell (e.g. from superscripts) where the evidence
originated in – RCT, meta-analysis … It is recommended that publication bias should be assessed when
there are 10 or more studies in a meta-analysis … Peer Reviewer #3 Results Why were so many systematic reviews and meta-analyses
included but only one … is that evidence is insufficient (insufficient in power) even when
there are several studies in a meta-analysis
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol-amendment.pdf
January 08, 2025 - Computerized cognitive interventions for
adults with ADHD: A systematic review and meta-analysis. … Atomoxetine for attention deficit hyperactivity
disorder in the adulthood: a meta-analysis and meta-regression … Hartung-Knapp-Sidik-Jonkman approach and its modification
for random-effects meta-analysis with few … Risk of bias: a simulation study of power to detect
study-level moderator effects in meta-analysis. … Bias in meta-analysis detected by a simple,
graphical test.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amended.pdf
February 07, 2025 - Data Synthesis: We will summarize the evidence qualitatively and quantitatively (e.g., meta-
analysis … , network meta-analysis) when possible. … To assess
whether pairwise meta-analysis will be appropriate, we will consider population factors such … In considering network meta-analysis,
we will evaluate how these factors are distributed across direct … Estimating interactions and subgroup‐
specific treatment effects in meta‐analysis without aggregation
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
February 07, 2018 - We will perform random-effects meta-analysis using the Hartung-Knapp adjustment
when sufficient data … The
arcsine difference as a measure of treatment effect in meta-analysis with zero cells. … Meta-analysis of rare binary events in treatment groups with unequal
variability. … Bias in meta-analysis detected by a
simple, graphical test. BMJ. 1997;315:629-34
22. … Comparison of two methods to detect
publication bias in meta-analysis.
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-maternal-health-grand-rounds-slides.pptx
January 01, 2023 - 15–12:30 Report Presentation: Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-analysis … Postpartum Care Discussants
Postpartum Care Up to One Year After Delivery:
A Systematic Review and Meta-Analysis … Patient-Centered Outcomes Research Institute (PCORI).
21
21
Context
22
Systematic review and meta-analysis … Delivery strategies for postpartum care: a systematic review and meta-analysis. … Postpartum care up to one year after pregnancy: a systematic review and meta-analysis.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
March 10, 2010 - with the appropriate analyses,
including assessments of the strength and quality of the evidence,
meta-analysis … We are suggesting that these comparisons be made within the context of
an individual patient data meta-analysis … A
prior meta-analysis have show different results when including
patients with or without LV dysfunction … While this may be accurate, data from other
meta analysis have shown otherwise when combing these studies … The prior mentioned meta-analysis differs
from our report in several notable ways.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
April 01, 2022 - of new studies eligible for meta-analysis (meta-analysis performed if new
evidence was large relative … to the studies in the original meta-analysis); consistency in findings
between the new studies and … the original meta-analysis (meta-analysis performed if findings
from new evidence appear inconsistent … Opioids for chronic low back pain
management: a Bayesian network meta-
analysis. … A Systematic Review and
Meta-Analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol.pdf
June 10, 2024 - Computerized cognitive interventions for
adults with ADHD: A systematic review and meta-analysis. … Atomoxetine for attention deficit hyperactivity
disorder in the adulthood: a meta-analysis and meta-regression … Hartung-Knapp-Sidik-Jonkman approach and its modification
for random-effects meta-analysis with few … Risk of bias: a simulation study of power to detect
study-level moderator effects in meta-analysis. … Bias in meta-analysis detected by a simple,
graphical test.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
October 12, 2016 - Peer Reviewer
#2
Methods (2) meta-regression or subgroup analysis based on
omega-3 dosing. … The objective of a meta-
analysis is to increase statistical power, so a
limitation on smaller studies … Moreover, adding to
existing meta-analysis was not done consistently. … We attempted to avoid using existing
meta-analyses in our review and have
removed the one prior meta-analysis … The effect sizes were 26% in the most
recent meta-analysis, and 51% and 87.5%,
respectively in two
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
July 01, 2010 - Systematic reviews in health care:
meta-analysis in context. 2nd ed. … An additional experience with 1153 cases (1985 to 1988) and a
meta-analysis. … A unification of models for meta-analysis
of diagnostic accuracy studies. … Meta-DiSc: a software for meta-
analysis of test accuracy data. … Quantifying heterogeneity in a meta-analysis.
Stat Med 2002;21:1539-58.
34.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
March 31, 2010 - Protocol
Project Title: Childhood Obesity Prevention Programs: A Comparative Effectiveness
Review and Meta-Analysis … meta-analysis of the findings will make unique contribution
to the literature. … Finally, we will conduct meta-analysis of
the results from the published studies, and generate a research … Data Synthesis (mainly meta-analysis)
For each Key Question, we will create a set of detailed evidence … Subgroup analysis: We will conduct subgroup meta-analyses when there are
sufficient data (at least
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/practical-considerations.pdf
March 01, 2022 - scoping, conducting searches, selecting studies,
abstracting data, assessing risk of bias, conducting meta-analysis … While an updated meta-analysis has the potential to improve
effect size estimates as more data became … As the evidence base matures, we will need to consider how often to update the meta-
analyses. … -
analysis
No Updating meta-
analysis more
frequently could allow
for modifications and
additional … need to increase
statistician FTE and have
available on an ongoing
basis, and plan for regular
meta-analysis
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
November 28, 2023 - .24 When meta-analysis is not
possible, we will provide a qualitative synthesis. … When meta-analysis is possible, we will
synthesize data using a Hartung, Knapp, Sidik, and Jonkman … (HKSJ)25 random effects
model in Comprehensive Meta-Analysis version 3 (Biostat, Englewood, New Jersey … If meta-analysis is not possible, we will present results
in a narrative Summary of Findings table. … Meta-Analysis with R. 2015.
27. Higgins JP, Thompson SG, Deeks JJ, Altman DG.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
July 13, 2011 - For example, in a
sensitivity analysis of a meta-analysis on the risk of nausea and vomiting during … must be able to be abstracted from data presented in the papers
(including Systematic Reviews and Meta-analyses … design
Head-to-head, double-blind, RCTs
Good or fair quality meta-analyses
Good or fair quality … recurrent depression
Study design
Head-to-head, double-blind, RCTs
Good or fair quality meta-analyses … (meta-analysis) of data from those studies.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
February 01, 2012 - trials to allow meta-
analysis, but patient-level meta-analysis would be required to evaluate the differential … Patient-Level Meta-analysis
Standard meta-analysis of existing studies is not feasible due to the large … Ethical Issues
Meta-analysis uses existing data. … Patient-Level Meta-analyses
Value of Study Design
Standard meta-analysis of existing studies is not … Ethical Issues
Meta-analysis uses existing data.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
July 01, 2010 - To assess the effect of heterogeneity (both clinical and methodological) on the
conclusions of our meta-analysis … For example, when a meta-analysis is performed, we will
evaluate the confidence interval around the … adjunctive thrombectomy and embolic
protection devices in acute myocardial infarction: a comprehensive meta-analysis … Meta-Analysis in clinical trials. Controlled Clin Trials.
1986 ;7 :177-188.
10. … Bias in Meta-Analysis Detected by a
Simple, Graphical Test. BMJ 1997;315:629-34.
11.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
February 01, 2013 - Meta-Analysis or
Individual Patient
Data Analysis
Across RCTs? … Meta-Analysis of
Observational
Studies?
New Observational
Study? … "[Publication Type] OR "meta-analysis as topic"[MeSH
Terms] OR "meta-analysis"[tw] OR "meta-analyses … Meta-Analysis of RCTs
If a new RCT is not feasible, then a meta-analysis of existing RCTs may provide … Meta-Analysis of Observational Studies
If a meta-analysis of RCTs is not feasible, the next most valid
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/meditation_executive.pdf
January 01, 2014 - Some
studies did not report enough information to be included in
meta-analysis. … This is a simple range of estimates, not a meta-analysis. … analysis (MA), the number of trials reporting
sufficient information to be included in a meta-analysis … Mindfulness-based stress reduction and
cancer: a meta-analysis. … Blood pressure response to
transcendental meditation: a meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
October 08, 2014 - Decisions about whether meta-analysis is appropriate will
depend on the judged clinical homogeneity … using the Hartung-Knapp method.31,32 Meta-regression
and subgroup analysis will be used to explore … A refined method for the
meta-analysis of controlled clinical trials with
binary outcome. … Random-effects meta-analysis of inconsistent
effects: a time for change. … analysis'/exp OR 'meta analysis' OR (('evidence base' OR
'evidence based'/exp OR 'evidence based' OR