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Showing results for "meta analysis".

1061. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
      February 01, 2012 - Data Analysis We presented evidence tables and a qualitative description of results for all studies. … We combined studies in a meta-analysis if the study design, population, interventions, and outcomes were … funding and the nature and extent of industry involvement in the design, conduct, supply of materials, analysis

1062. Executive Summary - Nutrition as Prevention for Improved Cancer Outcomes: Comparative Effectiveness Review No. 260 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-260-improved-cancer-outcomes-executive-summary_0.pdf
      May 01, 2023 - Geriatric analysis from PRODIGE 20 randomized phase II trial evaluating bevacizumab + chemotherapy … Prevalence of hospital malnutrition in cancer patients: a sub-analysis of the PREDyCES® study. … Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. … parenteral nutrition of esophageal cancer surgical patients receiving enteral nutrition: a comparative analysis

1063. Disposition of Comments Report for Comparison of Characteristics of Nursing Homes and Other Residential Long-Term Care Settings for People With Dementia (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_disposition-comments.pdf
      October 23, 2012 - Our review sought to include RCTs, NonRCTs, systematic reviews, meta analyses, subgroup and or post-hoc … The studies included in our analysis included RCTs, Non-RCTs, and prospective cohort studies. … Given the heterogeneity of the results, no meta- analytic approaches were used, which makes sense. … For this reason, we do not include poor quality studies in our analysis. … carried out by the authors of the review failed to provide strong evidence -- an indication that the analysis

1064. Disposition of Comments for Technical Brief 29 Women Living With HIV-AIDS (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/women-hiv_disposition-comments.pdf
      November 21, 2016 - We have added the following sentence at the end of the Data Abstraction and Data Analysis section: … We also added a paragraph in the discussion, limitations section: We did not conduct a detailed analysis … “of insurance on outcomes, despite having done no formal risk of bias analysis for them” We have added … Their first suggestion about how to move forward is via re- analysis of existing data sets. … The suggestion to mine existing data sources with meta-analyses was a good one.

1065. FRN 30: Outpatient Case Management for Adults With Medical Illnesses and Complex Care Needs: Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management-future_research.pdf
      June 01, 2015 - Stakeholders are not involved in the analysis or the writing of this report. … For the open-ended responses, we used a thematic analysis method to group these into categories. … - Practice/Policy Analysis. - Surveys. A.2. … care based case management for chronic diseases: rationale and design of a systematic review and meta-analysis … care based case management for chronic diseases: rationale and design of a systematic review and meta-analysis

1066. Disposition of Comments for CER 163 Appropriate Antibiotics (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
      January 27, 2016 - - analysis. … You can state here: “if meta-analysis was not suitable due to significant heterogeneity, a qualitative … Results and the results more generally present the most effective trials or studies and is not a meta-analysis … The Huang review was identified, but was not useable due to an error in the meta-analysis. … The Huang review was rated poor quality as noted due to an error in the meta-analysis, but our own

1067. Disposition of Comments CER 214 Stroke Prevention in Patients With Atrial Fibrillation (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
      October 30, 2019 - Rationale: The safety on-treatment analysis set was selected for the primary superiority analysis … Although we present graphically the meta analysis of the three Xa inhibitors, given the heterogeneity … We have then grouped the studies by drug when we combine them for individual meta analyses. 134. … and per-protocol analysis are provided. … and per-protocol analysis are provided.

1068. Masks for Prevention of COVID-19 in Community and Healthcare Settings (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-1.pdf
      December 01, 2021 - In a multivariate analysis, adherence to either mask was associated with decreased risk of influenzalike … We did not conduct meta- analysis. … Analysis of Subgroups or Subsets No formal subgroup analyses were performed. … Analysis for Adherence Cluster Trials: Adjustment for Clustering Overall Quality Rating … Simmerman J, 201138 Yes Unclear Yes No Unclear Yes 4.9% (23/465) excluded from analysis No

1069. Undescended-Testicle Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
      December 01, 2012 - In addition, quantitative analysis was used for KQ1a (imaging compared with laparoscopy) and KQ3 (surgical … Multivariate analysis demonstrated that neither age nor patent processus vaginalis modified outcomes … Overall, only eight good-quality studies were available for analysis, and this lack of good-quality … published on fertility outcomes, the specific measures are inadequate, as they focus only on semen analysis … The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses

1070. Disposition of Comments_Digestible Carbohydrate Intake and Maternal-Infant Outcomes: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-disposition-comments.pdf
      May 21, 2025 - Was only the control group included in the analysis of CHO intake and review outcomes of interest? … No meta-analysis was completed. Thank you for this comment. … The overall analysis adjusting for energy intake, infant sex, gestational age was significant (p=0.03 … As such, this is not reliable data and we did not include it in the analysis. … We acknowledge that this is a limitation, whether in the data collection, analysis, or reporting in

1071. Engaging Patients in Information Sharing and Data Collection: The Role of Patient-Powered Registries and Research Networks (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_white-paper.pdf
      September 01, 2013 - Meta- analysis across registries may be challenging or impossible should each competing registry collect … Collected data from each registry may be combined for analysis, although participation in a research … and research community as biased, inconsistent, and unable to provide a sufficient basis for valid analysis … Patient- reported outcomes as a source of evidence in off-label prescribing: Analysis of data from … Patient- reported outcomes as a source of evidence in off-label prescribing: Analysis of Data From

1072. Sleep-Apnea Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_surveillance.pdf
      April 01, 2012 - important expansion of treatment A6 Clinically important caveat A7 Opposing findings from discordant meta-analysis … A further analysis of the Wisconsin Sleep Cohort Study reported that sleep disordered breathing is … A further analysis of the Zaragoza Sleep Cohort study in patients with sleep-disordered breathing … A survival analysis. Ann Intern Med. 2007 Aug 21;147(4):224-33. PMID 17638714. 6. … 107 limit 7 to (guideline or meta

1073. Communication and Dissemination Strategies To Facilitate the Use of Health-Related Evidence (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-evidence-communication_executive.pdf
      November 01, 2013 - We did not retain studies with high risk of bias for analysis, presentation in the results chapters, … range of interventions and a plethora of outcomes; they were suffciently heterogeneous to preclude meta-analysis … compared strategies with a usual-care or no-treatment control group, but we included them in our analysis … This conceptual overlap complicated our analysis in at least two stages: creating meaningful classifcations … Coping with uncertainty: a naturalistic decision-making analysis.

1074. Glaucoma-Treatment Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_surveillance.pdf
      January 01, 2013 - important expansion of treatment A6 Clinically important caveat A7 Opposing findings from discordant meta-analysis … A survival analysis. Ann Intern Med. 2007 Aug 21;147(4):224-33. PMID 17638714. 4. … Lack of evidence for a link between latanoprost use and malignant melanoma: an analysis of safety databases … Timolol-Fixed Versus Unfixed Combinations or Monotherapy for Open-Angle Glaucoma: A Systematic Review and Meta-Analysis … for each procedure at 3, 4, and 5 years; medication changes were similar in both groups; survival analysis

1075. Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
      January 01, 2014 - Analysis of an existing registry, standard meta-analysis, or meta-analysis of individual patient data … Established methodological approaches such as matching and regression analysis, including propensity … Generally, given the ease of retrospective data analysis, care should be taken to avoid biases from … Ethical Issues There should be no ethical barriers to the analysis of existing databases or to conducting … Cost- effectiveness analysis of intravascular ultrasound guided percutaneous coronary intervention

1076. Technical Brief 13: Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
      December 01, 2012 - Thus, MSI-status needs to be measured and/or taken into consideration in the analysis. … Is there an effect of sample preparation, analysis, and/or tumor heterogeneity? … expression profiles as predictors of poor outcomes in stage II colorectal cancer: A systematic review and meta-analysis … • Was MSI (MMR) status considered in the overall analysis? o If so, how? … Analysis of select members of the E26 (ETS) transcription factors family in colorectal cancer.

1077. Rapid Evidence Product: Masks for Prevention of COVID-19 in Community and Healthcare Settings Version 2 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-2.pdf
      December 01, 2021 - In a multivariate analysis, adherence to either mask was associated with decreased risk of influenzalike … We did not conduct meta- analysis. … Analysis of Subgroups or Subsets No formal subgroup analyses were performed. … Analysis for Adherence Cluster Trials: Adjustment for Clustering Overall Quality Rating … Simmerman J, 201138 Yes Unclear Yes No Unclear Yes 4.9% (23/465) excluded from analysis No

1078. Disposition of Comments Report for Treatment for Hepatitis C Virus Infection in Adults (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
      November 27, 2012 - I think that the analysis is meaningful in regards to patients with genotype 2 and 3 HCV, where there … For KQ 2a we performed a sensitivity analysis of pooled results, excluding a trial of dual therapy … Recommend removing this from the primary analysis – may consider adding in as a sensitivity analysis … might make peginterferon alfa-2b more effective than alfa-2a – pushing the overall estimate from this meta-analysis … We did include the Marcellin trial in a sensitivity analysis.

1079. Long-Term Care for Older Adults Disposition of Comments Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_disposition-comments.pdf
      November 07, 2012 - qualitative review, as the evidence provided by the articles reviewed was not of a quality to support meta-analysis … , prospective cohort analysis and potential differences between new and existing users of NH and HCBS … Reviewer #6 Discussion There should be some discussion of the lack of subgroup analysis prior to the … How would this analysis be done? We included a description of ideal types. … Reviewer #9 Discussion Discussion-53: See the comments above on the cost analysis.

1080. Evidence Summary CER 208 Treatment For Bipolar Disorder In Adults (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-evidence-summary.pdf
      August 01, 2018 - More longitudinal data analysis techniques for intermittent followup would help, but that requires more … Social cognition in euthymic bipolar disorder: systematic review and meta-analytic approach. … Patient-reported outcomes in meta-analyses – Part 2: methods for improving interpretability for decision-makers