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Showing results for "meta analysis".

1041. Disposition of Comments for CER 158 Diagnosis of Gout (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout-diagnosis-disposition-160727.pdf
      February 24, 2016 - of the performance of tests or clinical features ‘compared to synovial fluid analysis’. … However, at various times throughout the analysis, data are included that use clinical criteria as … of having neither so many or so few features of gout that SF analysis was unnecessary. … identify sufficient numbers of similar studies, we did not consider conducting a random effects meta-analysis … These findings tend to support not undertaking MSU analysis in the primary care setting .

1042. Disposition of Comments Report for Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_disposition-comments.pdf
      October 23, 2014 - As described in detail in the report, we restricted the analysis to more current technologies (e.g., … We performed stratified analysis for studies that used a formal confidence rating scale; in general … (which you could argue is going to be the more clinically relevant analysis) would be helpful. … Peer Reviewer #1 General The analysis appropriately makes a distinction between surveillance and … Peer Reviewer #8 General As with all meta analyses, the quality of the ultimate observations and

1043. Disposition of Comments_Comparative Effectiveness Review No. 267: ADHD Diagnosis and Treatment in Children and Adolescents (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-disposition-comments.pdf
      March 25, 2024 - Indeed, that is the purpose of a systematic review and analysis. … We also added a subgroup analysis for sham controlled studies and a sensitivity analysis that excluded … this category (not just the treatment administered but also the dose, setting, participants, etc) meta-analytic … If an analysis is not possible, at least a discussion should be included. … Our task is to review the literature and, when possible, conduct meta-analyses that address the 3

1044. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
      January 01, 2007 - Direct evidence from head-to-head trials was considered sufficient to conduct meta-analyses for four … Differences in efficacy reflected in some of these meta-analyses are of modest magnitude and clinical … effectiveness study), nine placebo-controlled trials, one retrospective cohort study, and one set of meta-analyses … Indirect evidence from one fair-quality pooled analysis of head-to-head RCTs suggests that efficacy among … predict better the treatment response to optimize initial treatment selections (e.g., through genetic analysis

1045. PowerPoint Presentation (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
      June 01, 2012 - It contains meta-analyses of genetic association studies. … Its Web site includes many meta-analyses of genetic association studies and a source called the HuGE … Was the timing of analysis equal for both study groups (if applicable)? … Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and … Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and

1046. PowerPoint Presentation (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-genetic.ppt
      June 01, 2012 - It contains meta-analyses of genetic association studies. … Its Web site includes many meta-analyses of genetic association studies and a source called the HuGE … Was the timing of analysis equal for both study groups (if applicable)? … Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and … Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and

1047. Long-Term-Care-Adults Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
      November 01, 2012 - studies that accounted for differences in case mix across setting using techniques such as multivariate analysis … Throughout the analysis, we considered AL as a separate category within HCBS because it encompasses … Since we did not conduct a quantitative meta-analysis of the findings, we based precision on the individual … Although relevant international and grey literature studies supplemented our analysis, we did not include … settings • More generalizable samples Differences within subgroups • No studies performed subgroup analysis

1048. Cell-Free-Dna-Appendix-C-Prepub-Final (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c-prepub-final.xlsx
      January 01, 2025 - screening (analysis 2). … 4.4 Were all patients included in the analysis? … Another 1,498 that were enrolled had samples reserved for future analysis and were not used in the analysis … Mortality as End Points in Randomized Clinical Trials of Cancer Screening: A Systematic Review and Meta-Analysis … Strong association between reduction of late-stage cancers and reduction of cancer-specific mortality in meta-regression

1049. Cell-Free-Dna-Final-App-C (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-final-app-c.xlsx
      January 01, 2025 - screening (analysis 2). … 4.4 Were all patients included in the analysis? … Another 1,498 that were enrolled had samples reserved for future analysis and were not used in the analysis … Mortality as End Points in Randomized Clinical Trials of Cancer Screening: A Systematic Review and Meta-Analysis … Strong association between reduction of late-stage cancers and reduction of cancer-specific mortality in meta-regression

1050. Retention Strategies for Medications for Addiction Treatment in Adults With Opioid Use Disorder: A Rapid Evidence Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
      August 01, 2020 - We reported retention outcomes for each included study, using intention-to-treat (ITT) analysis; if … Key Question 1: Effectiveness and Comparative Effectiveness of MAT Retention Strategies An SR with meta-analysis … used a rapid review methodology, which involved searching limited databases, not conducting formal meta-analyses … Effects of medication-assisted treatment on mortality among opioids users: a systematic review and meta-analysis … Mortality risk during and after opioid substitution treatment: systematic review and meta-analysis

1051. Radiation Therapy for Bone Metastases (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
      August 10, 2022 - Findings will be synthesized qualitatively (e.g., ranges and descriptive analysis, with interpretation … of results) and quantitatively (meta-analysis) when appropriate. … If sufficient numbers of RCTs (>10) are available, quantitative funnel plot analysis may be done. … A Further Analysis of the Dutch Bone Metastasis Study. … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report

1052. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacological Interventions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
      April 15, 2021 - An analysis of online pregnancy message boards: Mother-to-mother advice on medication use. … reuptake inhibitors and risk for persistent pulmonary hypertension of the newborn: a systematic review, meta-analysis … , and network meta- analysis. … Particularly if the studies are often discussed or cited by other reviews or meta-analyses, it is important

1053. White Paper_Living Systematic Reviews: Examining Excluded Full-Text Articles To Better Understand the Evidence Base on Plant-Based Treatments for Chronic Pain (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/living-systematic-reviews-full-text-articles-white-paper.pdf
      January 01, 2024 - total N=1,985) were randomized controlled trials12,16,18,20,22,23 and one17 (n=191) was a post-hoc analysis … tolerability of medicinal cannabinoids in patients with multiple sclerosis: a systematic review and meta-analysis … An updated analysis of clinical outcome measures across patients from the UK medical cannabis registry … Assessment of clinical outcomes in patients with fibromyalgia: analysis from the UK Medical Cannabis … Assessment of clinical outcomes in patients with fibromyalgia: analysis from the UK Medical Cannabis

1054. The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
      September 19, 2014 - They have a serious or “fatal” flaw or combination of flaws in design, analysis, or reporting; large … We did not attempt meta-analyses because of the small number of studies available for each Key Question … in VA patients with chronic pain and controlled well for confounders using a propensity-adjusted analysis … We did not attempt meta-analysis or assess for publication bias using graphical or statistical methods … Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects.

1055. Disposition of Comments for Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer: An Update of a 2008 Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
      December 16, 2014 - Missing in the analysis, are the statistical analysis plans for the RCT trials considered, as many did … We performed only qualitative analysis in this update. … Peer Reviewer 2 Discussion and Conclusion one meta-analysis of 6 vs 3 or 4 mos of HT for men treated … The points are clearly presented but the analysis can be improved. Thank you. … I am not sure why men with T3 disease were excluded form analysis 5.

1056. Multiple-Sclerosis Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
      April 01, 2015 - A 2013 Cochrane overview review and network analysis of 44 2- to 3-year trials of DMTs for MS found … Techniques to adjust for selection bias, such as regression analysis or propensity scores, are more … Analysis of current multiple sclerosis registries. Neurology. 2011 Jan 4;76(1 Suppl 1):S7-13. … Immunomodulators and immunosuppressants for multiple sclerosis: a network meta- analysis. … PRISMS Study Group, the University of British Columbia MSMRI Analysis Group.

1057. Methods Guide for Medical Test Reviews Chapter 4 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-search_methods.pdf
      July 01, 2012 - web_of_science Subscription required 4-6 In addition to bibliographic databases and citation analysis … Sampson M, Barrowman NJ, Moher D, et al., Should meta-analysts search Embase in addition to Medline

1058. Management of Renal Masses and Localized Renal Cell Carcinoma: Current State of the Evidence (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_clinician.pdf
      July 01, 2017 - Thermal Ablation (TA) Cancer-specific survival 9 (14,625) A meta-analysis suggested better survival

1059. Making Healthcare Safer IV: Summary of Findings, 2023-2024 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-1-year-final-report-updated-title_0.pdf
      May 01, 2024 - Medical Director of Clinical and Quality Analysis, Information Systems, Partners HealthCare System … the country is at a relative standstill in patient safety progress,”7 a claim supported by a recent meta … However, a meta-analysis reported reduced mortality and in another systematic review, one of two included … severity, and nature of preventable patient harm across medical care settings: systematic review and meta … - analysis.

1060. Arthritis-Psoriatric Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
      April 01, 2012 - Methods A Technical Expert Panel was employed for the finalization of the KQs and review of the planned analysis … controlled trials, 0 head- to-head nonrandomized controlled trials, 10 placebo- controlled trials, 3 meta-analyses