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41. Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_policymaker.pdf
    August 01, 2016 - Medications approved by the U.S. … In addition, medications such as topiramate have not been approved to treat AUD but have been used … However, medications are underutilized in treating AUD, thus providing opportunities for expanding … in combination with a psychosocial cointervention; the potential benefits of using the medications … b These medications have not been approved by the U.S.

42. Data Points #19: Medication Use in Medicare | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/medicare-medication-use/research
    April 23, 2014 - Use of multiple medications is common in this population. … In particular, the number of unique medications and number of unique medication groups is greatest for … Multiple medications and use of psychotropic drugs increases the possibility of adverse drug events. … Part D is required to cover nearly all antipsychotic and antidepressant medications to protect against … the risk associated with interruptions in these medications.

43. Ventricular Arrhythmias and Cerebrovascular Events in the Elderly Using Conventional and Atypical Antipsychotic Medications | Effective Health Care Program
    effectivehealthcare.ahrq.gov/products/antipsychotic-medicine-cardiovascular-elderly
    March 18, 2009 - Arrhythmias and Cerebrovascular Events in the Elderly Using Conventional and Atypical Antipsychotic Medications … Arrhythmias and Cerebrovascular Events in the Elderly Using Conventional and Atypical Antipsychotic Medications

44. Comparative Safety of Conventional and Atypical Antipsychotic Medications: Risk of Death in British Columbia Seniors | Effective Health Care Program
    effectivehealthcare.ahrq.gov/products/atypical-antipsychotics-seniors-death
    August 29, 2007 - Comparative Safety of Conventional and Atypical Antipsychotic Medications: Risk of Death in British Columbia … Research Report Comparative Safety of Conventional and Atypical Antipsychotic Medications

45. Evaluation of Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
    February 01, 2008 - Evaluation of Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy … , or other narrow therapeutic index medications (medications where the difference between the minimum … and comparing innovator antiepileptic medications to their generic counterparts. … to newer antiepileptic medications, compare innovator antiepileptic medications to generic antiepileptic … ) will be compared to their corresponding generic medications within that same class.

46. Reduction in Medication Use after Bariatric Surgery (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/bariatric-surgery_research.pdf
    June 01, 2010 - Prompt reduction in use of medications for comorbid conditions after bariatric surgery. … We hypothesized that use of these medications would decrease after surgery. … Similarly, the mean prescription fills for antihypertensive medications and lipid-lowering medications … in risks associated with medications may be highly valued by patients. … Medications of Interest Medication Category Therapeutic Classes Antihypertensive Medications angiotensin

47. A Multicenter, Observational Cohort Study to Assess the Cardiovascular Risks of Medications Prescribed for Attention Deficit Hyperactivity Disorder | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/adhd-medicines-risks
    January 01, 2005 - A Multicenter, Observational Cohort Study to Assess the Cardiovascular Risks of Medications Prescribed … Archived A Multicenter, Observational Cohort Study to Assess the Cardiovascular Risks of Medications

48. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
    January 01, 2005 - Some patients have frequent, severe symptoms requiring long-term regular use of antireflux medications … These include intermittent, periodic, or continuous use of prescription or over-the-counter medications … , long-term followup of a landmark randomized controlled trial comparing medications with surgery found … who do not need long-term antisecretory medications. … The proportion of patients freed from long-term antireflux medications is unclear. Surgical vs.

49. CER 173 Executive Summary: Diabetes Medications for Adults With Type 2 Diabetes: An Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
    January 01, 2015 - both arms had medications expected to maintain or decrease weight, or both arms had medications expected … We used this exclusion to avoid interactions between medications. … Oral Diabetes Medications for Adults With Type 2 Diabetes: An Update. … Patient preferences for noninsulin diabetes medications: a systematic review. … Diabetes Medications for Adults With Type 2 Diabetes: An Updated.

50. Update Topic Brief CER 27 NSD FINAL_SJ final (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
    January 17, 2014 - Oral Diabetes Medications … Diabetes Nomination Summary Document Results of Topic Selection Process & Next Steps § Oral Diabetes Medications

51. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
    March 01, 2011 - Layout 1 Oral Diabetes Medications for Adults With Type 2 Diabetes. … We also included comparisons with combinations of medications. … Diabetes medications varied in terms of their effects on body weight. … We recommend that studies allowing use of “background” medications identify which medications were allowed … Oral Diabetes Medications for Adults With Type 2 Diabetes. An Update.

52. Topic Suggestion Description | Effective Health Care Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-evidence-exists-for-programs-to-increase-patient-adherence-to-prescription-medications-which-programsapproaches-are-most-effective-at-increasing-adherence-for-which-populations-and-conditions-if-little-or-no-evidence-exi
    August 12, 2009 - What evidence exists for programs to increase patient adherence to prescription medications? … Failure to take prescribed medications impacts research and the ultimate availability of evidence, let … While comparative effectiveness studies have done a strong job of comparing particular medications, few … studies, if any, have looked at the medications from the perspective of adherence of patients in taking … medications that are shown to be evidence-based.

53. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
    September 01, 2009 - Recent clinical trials have demonstrated the efficacy of three medications—tamoxifen citrate, raloxifene … However, use of risk-reducing medications for breast cancer is believed to be low in the United States … Use of medications to reduce risk of breast cancer Adverse effects of medications 1, 3, 4 Women … and may drive decisions for risk-reducing medications as much or more than benefits do. … Comparative Effectiveness of Medications To Reduce Risk of Primary Breast Cancer in Women.

54. Alcohol-Misuse-Drug-Therapy Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
    January 27, 2012 - Many additional medications have been used off label or studied for treatment of AUDs. … KQ 4: Are medications for treating adults with AUDs effective in primary care settings? … KQ 5: Are any of the medications more or less effective than other medications for men or women, older … Our review focused on benefits and harms of medications and how they compare with other medications, … Medications for unhealthy alcohol use: across the spectrum.

55. Comparative Safety of Conventional and Atypical Antipsychotic Medications: Risk of Death in British Columbia Seniors | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/atypical-antipsychotics-seniors-death/research
    August 29, 2007 - Comparative Safety of Conventional and Atypical Antipsychotic Medications: Risk of Death in British Columbia … Health Canada and Food and Drug Administration (FDA) Advisory has warned that atypical antipsychotic medications … Patients Senior BC residents who were initiated on antipsychotic medications and had no recorded cancer

56. Topic Suggestion Description | Effective Health Care Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/treatment-for-depression
    September 21, 2021 - I am someone you responds well to Serotonin Medications esp. SSRI's for depression. … What has the highest Serotonin level medications left to try? I am trying Doxepin. 2. … How to Raise my Serotonin levels with other medications available and stop the suicidal thoughts. … I have found best out comes are with SSRI type medication or medications that increases serotonin levels

57. Attention Deficit Hyperactivity Disorder Medications and Risk of Serious Cardiovascular Disease in Children and Youth | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/adhd-heart-disease-adults/research
    November 01, 2011 - Attention Deficit Hyperactivity Disorder Medications and Risk of Serious Cardiovascular Disease in Children … Objective To examine the association between use of ADHD medications and the risk for serious cardiovascular … there was no evidence of increased risk of serious cardiovascular events for current users of ADHD medications

58. A Comparative Effectiveness Study of Intensive Glycemic Control vs. Less Intensive Control in Type 2 Diabetes | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/glycemic-control/abstract
    December 15, 2009 - Patients who are already being treated fairly intensely (e.g., with either 2 or more oral medications … , or with basal insulin), are of particular interest as these medications are associated with harms such … Research Questions: Among the key clinical questions is whether initiation of additional anti-diabetic medications … Patients will include those taking two anti-diabetic medications who have Hb A1c that increases from … Evidence of interactions between intensification of anti-diabetic medications and stratifying variables

59. Research and Surveillance Methods for Improving Medication Safety Using Administrative Claims Databases | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/medicine-safety-databases/abstract
    January 01, 2005 - will encompass surveillance for process measures such as misuse, over- and under-use of prescription medications … medication safety using administrative databases as well as studies of specific misuse and underuse of medications … assembled the literature, have identified examples of process measures (misuse, overuse, and underuse of medications

60. Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/alcohol-misuse-drug-therapy/research-protocol
    April 26, 2013 - Medications for Alcohol-Use Disorders From the 1950s until the early 1990s, the pharmacotherapy for … The medications are usually prescribed for 3 to 12 months. … Table 3 describes medications that have been used (off-label) or studied for treatment of AUDs. … these medications. … Key Question 5: Are any of the medications more or less effective than other medications for men or