-
effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
October 01, 2007 - Nevertheless, random-
ized controlled trials have major limitations when they are
used to assess the role of medications … it is possible to include a wide
variety of participants and assess long-term exposures, in-
cluding medications … With respect to prescribed medications,
this bias is called confounding by indication.2 It stems from … The potential for confounding is probably larger in
observational studies assessing medications than … visits† 1.3 1.3–1.3 1.1 1.0–1.4 1.1 0.9–1.3
No. hospitalizations† 0.9 0.9–0.9 1.1 0.9–1.3 1.0 0.9–1.2
Medications
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
September 01, 2009 - Medications available for lipid-lowering therapy have
various mechanisms of action and pharmacokinetic … Statins are the most studied and prescribed group of
lipid-lowering medications and may be used alone … Combining different types of medications may appear
attractive but could result in more harms, be less … combinations would also be
of some interest, although the potential for BAS to
interact with other medications … In studies employing a
mixture of statin medications and/or doses, results
should be reported by medication
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Therefore, physicians may also
recommend weight-loss medication.40 If goals are not achieved with medications … Diet and exercise and currently available medications are ineffective in
long-term weight loss. … clinical guidelines on using pharmacology to manage obesity suggest using
FDA-approved weight-loss medications … Despite the limitations and concerns, this is a novel agent in the overall paucity of antiobesity
medications … Clinical policy bulletin no. 0039: weight
reduction medications and programs. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1406.pdf
June 01, 2014 - smart-pill” technology or “digital medicine,” has been
developed for use with oral pill or capsule medications … The company is working with selected pharmaceutical manufacturers to choose
medications for sensor … At a postdischarge visit, typical
activities are as follows: the discharge worker reconciles medications … medication of interest.”36,37 Patients can
ingest up to 30 sensors per day.38 Patients take oral medications … At the postdischarge visit, the
discharge worker reconciles medications, reviews medication use, arranges
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0713-140625.pdf
January 07, 2014 - .
§ Common medications for LUTS/BPH include alpha-blockers, beta-3 agonists, anticholinergic agents
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_overview.pdf
March 27, 2014 - Systemic Juvenile Idiopathic Arthritis
and Tuberculosis Screening Among Children Receiving Biologic Medications
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1306.pdf
October 01, 2014 - Bipolar Depression and
Major Depressive Disorder
Key Facts: Despite widespread use, approved medications … Only a fraction of treated patients respond within a week
of starting any of the many medications available … Food and Drug Administration (FDA) for treating PMD.3 Effective
medications are needed for this condition … typically the first-line treatment and involves concomitant use of antidepressant and antipsychotic
medications … Unmet need and health outcomes: An extremely important unmet need exists for rapidly
effective medications
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - and Young Adults: Systematic Review
Update
Executive Summary
Introduction
The use of psychotropic medications … Exclusion of non-antipsychotic medications as comparator. … Only one study
permitted concomitant psychotropic medications including
stimulants. … Treatment of young people with
antipsychotic medications in the United States. … Medicaid prior authorization policies
for pediatric use of antipsychotic medications.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-gain-future_research.pdf
January 01, 2020 - What is the comparative effectiveness of medications for the prevention of weight gain among adults? … KQ4 What is the comparative effectiveness of medications for the prevention of weight gain among adults … or insulin, given their high risk of weight gain,
attributed in part to side effects from these medications … The majority of stakeholders identified
medications as the lowest priority strategies for weight gain … Stakeholders commented that they ranked medications lower due to concerns about the long-
term viability
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol-final.pdf
October 15, 2024 - will require understanding moderators in the receipt of menopause therapy, including the cost of
medications … bioidenticals, testosterone, and hormonal contraceptives, we will limit inclusion to FDA-
approved medications … For testosterone and hormonal contraceptives, we will limit to FDA-
approved medications. … For testosterone and hormonal contraceptives, we will limit to FDA-
approved medications. … b Topic medications are excluded: Vaginal ring (Estring 7.5 mcg estradiol per day released over 3 months
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol.pdf
October 15, 2024 - will require understanding moderators in the receipt of menopause therapy, including the cost of
medications … bioidenticals, testosterone, and hormonal contraceptives, we will limit inclusion to FDA-
approved medications … For testosterone and hormonal contraceptives, we will limit to FDA-
approved medications. … For testosterone and hormonal contraceptives, we will limit to FDA-
approved medications. … b Topic medications are excluded: Vaginal ring (Estring 7.5 mcg estradiol per day released over 3 months
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
December 01, 2013 - Thus, an unmet need has existed for novel,
effective medications to improve outcomes in this patient … They also use inhaled medications,
ventilators, and chest physiotherapy singly or in combination to … Treatment includes
smoking-cessation counseling and nicotine-addiction treatment, medications to address … Available:
http://www.onlinepharmacycatalog.com/drugs-
medications/antibiotics/azithromycin/zithromax … Mechanisms of action and
clinical application of macrolides as
immunomodulatory medications.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
April 01, 2011 - The clearest evidence favors the use of medications to
address challenging behaviors. … Both medications also cause significant
side effects, however, including marked weight gain,
sedation … We rated the strength of evidence as high for the adverse
effects of both medications, moderate for the … For medical studies, data across classes of medications
are likely to be transferable outside of the … A few medications show benefit for repetitive behaviors
or associated symptoms, with the clearest evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
April 01, 2020 - • At short-term followup, evidence showed no
differences between opioids versus nonopioid
medications … In the United States, prescription
of opioid medications for chronic pain
more than tripled from 1999 … prescription of long-acting opioids associated with
increased risk of all-cause mortality vs. nonopioid medications … increased risk of overdose,
16
with most pronounced risk occurring soon after
initiation of these medications … All-cause and
drug-related medical events associated with overuse of
gabapentin and/or opioid medications
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - The review was designed to evaluate the effectiveness
of available strategies—exercise, medications, … What is the comparative effectiveness of exercise
training, medications (cilostazol, pentoxifylline) … Scientific information packets
were requested from the manufacturers of medications and
devices and … For KQ 1, this consisted of studies of all PAD
populations comparing antiplatelet medications (aspirin … For KQ 2, this consisted of studies of PAD
patients with IC comparing exercise therapy, medications
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
January 01, 2024 - without modifiable CV risk factors,
including
o Dyslipidemia (including if taking lipid-
lowering medications … (≥18 years old)
Both Key Questions
● Participants with a health-related
condition or taking medications … that
impact fat absorption, fat metabolism
● Participants taking weight loss
medications, including
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
January 01, 2024 - without modifiable CV risk factors,
including
o Dyslipidemia (including if taking lipid
lowering medications … (≥18 years old)
Both Key Questions
● Participants with a health-related
condition or taking medications … that
impact fat absorption, fat metabolism
● Participants taking weight loss
medications, including
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-high-risk-drugs-rapid-response.pdf
January 01, 2024 - Anticoagulation medications help prevent life-threatening events such as
pulmonary embolism, but they … Regarding specific anticoagulants, one of the touted advantages of newer DOAC
medications (e.g., apixaban … However, the newer medications still
require careful dosing and monitoring. … The first, Medications at Transitions and Clinical Handoffs
(MATCH) Toolkit for Medication Reconciliation … Second, a
series of open-
ended
questions to
assess patient
understanding
of medications
and VTE
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_executive.pdf
January 01, 2020 - Obesity can also be caused by medications used
to treat chronic disease, as is the case for antipsychotic … Diabetes and some cancer medications are
also associated with weight gain. … Interventions for patients
initiating diabetes medications, tamoxifen, and aromatase
inhibitors are … Oral Diabetes Medications
for Adults With Type 2 Diabetes: An Update [Internet]. … Diabetes medications and body weight.
Expert Opin Drug Saf. 2009;8(5):573-84.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_executive.pdf
September 01, 2011 - Layout 1
Background
Antipsychotics medications are approved
by the U.S. … These medications are
commonly divided into two classes,
reflecting two waves of historical
development … for decades, the conventional
antipsychotics also produced various side
effects requiring additional medications … This report covers the following off-label uses of atypical
antipsychotic medications: anxiety, ADHD, … Sub-Key Question 2: How do atypical antipsychotic
medications compare with other drugs, including first