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81. PHARMACO-EPIDEMIOLOGIC METHODS FOR A STUDY OF (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-cardiovascular-elderly_research.pdf
    February 01, 2009 - Although an FDA Advisory has warned that atypical antipsychotic medications (APMs) increase mortality … Elderly, antipsychotic medications, conventional, atypical, arrhythmias, cerebrovascular accidents. … Diabetes was defined by the presence of diagnoses plus use of anti-diabetic medications. … Risk of death in elderly users of conventional vs. atypical antipsychotic medications. … , total number of medications, hospitalizations, and nursing home stays.

82. Diabetes Medicines | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/diabetes-medicines
    November 29, 2016 - Help Manage Type 2 Diabetes Systematic Review Archived April 19, 2016 Diabetes Medications … Programs for Diabetes Mellitus Research Protocol Archived January 22, 2015 Diabetes Medications … Methods for Diabetes Mellitus Systematic Review Archived March 15, 2011 Oral Diabetes Medications … Research Protocol Archived April 5, 2010 Comparative Effectiveness and Safety of Oral Diabetes Medications … Systematic Review Archived July 16, 2007 Comparative Effectiveness and Safety of Oral Diabetes Medications

83. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND__0355_09-22-2010.pdf
    January 01, 2010 - For patients with insomnia, how do commonly used medications compare for effectiveness and harms, including … There is uncertainty surrounding which medications are most effective and when medications should be

84. Making Healthcare Safer IV: Deprescribing to Reduce Medication Harms in Older Adults | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/deprescribing-mhs4/protocol
    August 01, 2023 - concurrent increase in the prevalence of polypharmacy (commonly defined as using 5 or more chronic medications … ) 2 or potentially inappropriate medications (PIMs). … Deprescribing interventions take many forms, including reviews of medications by clinical pharmacists … , identifying medications based on established criteria or lists (e.g., Beers, STOPP), point-of-prescribing … Prevalence of potentially inappropriate medications use among older adults and risk factors using the

85. 1. Which patients benefit the most from MTM services? 1.1. Which factors, or combinations of factors, are most predictive of the clinical benefit of MTM services? 1.1.1. Disease factors (e.g., diabetes vs COPD ; multi-morbidity vs single… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/1-which-patients-benefit-the-most-from-mtm-services-11-which-factors-or-combinations-of-factors-are-most-predictive-of-the-clinical-benefit-of-mtm-services-111-disease-factors-eg-diabetes-vs-copd-multi-morbidity-vs-single-di
    November 01, 2017 - Medication factors (e.g., number of medications, total expenditures on medications, patient out-of-pocket … expenditures on medications, or type of medication [high-risk drugs])? … In turn, the improved use of medications may lead to improved clinical outcomes (e.g., blood pressure … Medications are a key component of treating chronic disease, yet research has shown that the quality … These limitations may preclude enrollment of patients with poor adherence to their chronic medications

86. Engaging-Caregivers-Appendix-C (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-c.xlsx
    January 08, 2024 - Study Use Accurate Methods for Ascertaining Exposures and Potential Confounders (e.g., Age, Sex, Other Medications … the Study Perform Appropriate Statistical Analyses on Potential Confounders (e.g., Age, Sex, Other Medications

87. Outcomes Associated With Tiotropium use in Chronic Obstructive Pulmonary Disease Patients | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/copd-anticholinergic-medicines/research
    January 01, 2020 - Tiotropium in combination with two other medications was associated with increased risk of mortality, … We measured use of respiratory and other medications that preceded the medication switch. … Finally, use of more medications may be indicative of more severe disease and even though we controlled … Many combinations of medications were reported that have not previously been investigated. … Project Timeline Comparative Effectiveness of Anticholinergic Medications in Patients with Chronic

88. Future Research Needs Document (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/breast-cancer-risk-reduction_research.pdf
    October 25, 2010 - However, the CER also found that the medications have important adverse effects. … “What alternatives to medications are most important to study or most promising?” … Vitamin A derived medications (e.g. … medications such as aromatase inhibitors. … for risk reducing medications as much or more than benefits.

89. Comparative Effectiveness and Safety of New Therapies (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diabetes-glucose-control_research.pdf
    July 01, 2010 - Twenty-two percent of users were obese, compared to 11 to 15% using other medications. … (i.e., was on oral medications or no medications), (b) insulin, (c) exenatide, or (d) both insulin … Most patients in all of the groups were also using oral hypoglycemic medications. … The group with the fewest complications was the group on no injectable medications or on no medications … Regarding use of oral hypoglycemic medications, 75% and 58% of patients had been on metformin and a

90. Psychosocial and Pharmacologic Interventions for Disruptive Behavior Disorders in Children and Adolescents: Current State of the Evidence | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/disruptive-behavior-disorder/clinician
    June 01, 2021 - A wide range of psychotropic medications--including anticonvulsants, antipsychotics, mood stabilizers … Use of the medications has increased substantially in recent years. … Some medications used to treat DBDs have not been approved by the U.S. … However, only a few studies evaluated the medications included in this review, and their results did … Adverse effects of medications reported in included studies were mild or moderate, but the ability of

91. Research and Surveillance Methods for Improving Medication Safety Using Administrative Claims Databases | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/medicine-safety-databases/abstract
    November 01, 2017 - will encompass surveillance for process measures such as misuse, over- and under-use of prescription medications … medication safety using administrative databases as well as studies of specific misuse and underuse of medications … assembled the literature, have identified examples of process measures (misuse, overuse, and underuse of medications

92. Management of Postpartum Hypertensive Disorders of Pregnancy | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/hypertensive-disorders-pregnancy/research
    October 01, 2023 - ) There is insufficient evidence regarding comparative benefits and harms of other antihypertensive medications … toxicity) (high SoE) There is insufficient evidence regarding whether nifedipine or other antihypertensive medications … There was insufficient evidence regarding the comparative benefits and harms of other antihypertensive medications … insufficient evidence regarding potential harms of concomitant use of nifedipine or other antihypertensive medications … However, further evidence is needed regarding the comparative benefits and harms of the antihypertensive medications

93. Topic 0562 Treatments for Biploar Disorder NSD FINAL SJ (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0663-131114.pdf
    April 10, 2013 - remission of co-occurring substance use disorder; reduced impact of side effects of mood-stabilizing medications … comparative effectiveness of available treatments including psychotherapy, other psychosocial treatments, medications … Standard pharmacological therapies for bipolar disorder can include mood stabilizing medications such

94. CERs Report cover (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
    September 01, 2010 - However, the CER also found that the medications have important adverse effects. … ‖ ―What alternatives to medications are most important to study or most promising? … Vitamin A derived medications (e.g. … medications such as aromatase inhibitors. … for risk reducing medications as much or more than benefits.

95. Psychosocial and Pharmacologic Interventions for Disruptive Behavior Disorders in Children and Adolescents: Current State of the Evidence (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_clinician.pdf
    August 01, 2016 - However, only a few studies evaluated the medications included in this review, and their results did … Adverse effects of medications reported in included studies were mild or moderate, but the ability … A wide range of psychotropic medications—including anticonvulsants, antipsychotics, mood stabilizers … Use of the medications has increased substantially in recent years. … Some medications used to treat DBDs have not been approved by the U.S.

96. Evidence-based Practice Center Systematic Review Protocol - Management of Infantile Epilepsies (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-disposition-comments.pdf
    October 25, 2022 - There is so much variability on medications for each recognized disorder, and a proper diagnosis can … For instance, in Dravet syndrome (DS), in the list of medications under Main Points (Levetiracetam … Ann Sodders, No affiliation listed Methods In regards to medications, what about other medications … A list of all medications considered appears in the appendix. … We note in the Discussion any oft-prescribed medications for which we included no evidence, such as

97. Mental Disorders | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/mental-disorders?page=4
    September 27, 2011 - Medications and counseling can help many mental disorders. … Arrhythmias and Cerebrovascular Events in the Elderly Using Conventional and Atypical Antipsychotic Medications … Research Report August 29, 2007 Comparative Safety of Conventional and Atypical Antipsychotic Medications

98. Microsoft Word - ehcrr#2toCSI.doc (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
    August 01, 2007 - Health Care Number 2 Research Reports Comparative Safety of Conventional and Atypical Antipsychotic Medications … Mortality in users of conventional and atypical antipsychotic medications in British Columbia seniors … Effective Health Care Research Report Number 2 1 Introduction Antipsychotic medications (APMs) are … Risk of death in elderly users of conventional vs. atypical antipsychotic medications. … Atypical Antipsychotic Medications (APMs).

99. S77 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/s77.pdf
    October 01, 2007 - Because 64% of the medications purchased by the VA are generic,7 we used this percentage in calculating … In contrast to the VA, Part D plans charge only 1 copayment for medications dispensed with a 3-month … We assumed that half of veteran prescriptions are ongoing regular medications that can be supplied with … This modeling involved only medications received through the VA. … Because some veterans already use non-VA pharmacies to fill some or all of their medications,11 having

100. Use of Electronic Medical Records and Administrative Claims Data for Assessing Type 2 Diabetes Care | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/diabetes-claims-data/research
     November 01, 2017 - conducted a literature search to identify publications focusing on the efficacy and effectiveness of medications … this review to determine which glycemic indicators should be assessed to determine the adequacy of medications … In both patient cohorts, we described comorbidities present when DMT2 was diagnosed and medications used … versus text-mining results indicated that neither data source provided complete reporting of patients’ medications … The use of medications appeared to be somewhat more intensive in the Medicaid population.