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241. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
     February 10, 2010 - acute symptoms and exacerbations).1 Despite guidance surrounding asthma self-management education and medication … found that adults with asthma and parents of children with asthma have concerns about regular use of medication …  Children >5 years with asthma of any type and severity, symptomatic or using asthma medication … nocturnal control, missed school/work, daily activity tolerance or restrictions)  Quick-relief medication … use, long-term control medication use, and pulmonary function.

242. Cover Page (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
     September 01, 2007 - currently no widely implemented mechanism for the reverse flow of information on adverse events and medication … also deficient in providing background data on number of patients being administered a particular medication … A baseline information questionnaire is administered at the start of a medication to collect basic … information about the patient’s health status before medication. … Cohen MM, Kimmel NL, et al. (2005) “Medication Safety Program Reduces Adverse Drug Events in a Community

243. Cover Page (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
     September 01, 2007 - currently no widely implemented mechanism for the reverse flow of information on adverse events and medication … also deficient in providing background data on number of patients being administered a particular medication … A baseline information questionnaire is administered at the start of a medication to collect basic … information about the patient’s health status before medication. … Cohen MM, Kimmel NL, et al. (2005) “Medication Safety Program Reduces Adverse Drug Events in a Community

244. Antipsychotics-Children-Surveillance-150120 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
     October 01, 2014 - • Medication adherence and persistence. • School performance and attendance. … Long-term effects of ADHD medication on adult height: results from NESARC. … Medication adherence was not significantly different We found no new studies of medication adherence … or another atypical antipsychotic medication or the same atypical antipsychotic medication but at a … with standard/higher doses of the same medication.

245. Future Research Needs for the Comparative Effectiveness of Breathing Exercises and/or Retraining Techniques in the Treatment of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment-future_research.pdf
     September 01, 2012 - advocated for the control of asthma given the range of asthma severity and concerns about long-term medication … to guideline-based care, with the primary goals of improving asthma control and reducing the use of medication … PEF and PFV); cardiovascular outcomes (e.g., heart rate); quality of life (e.g., stress, anxiety); medication … There was moderate evidence that showed a reduction in asthma symptoms and reliever medication use with … , but no more likely to improve asthma symptoms, medication use, quality of life, or pulmonary function

246. Research Protocol: Diabetes Medications for Adults With Type 2 Diabetes: An Update Focused on Monotherapy and Add-On Therapy to Metformin (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
     January 01, 2015 - disease in adults in the U.S.4 Costs related to diabetes were approximately $245 billion in 2012.1 Medication … Including insulin, there are 10 medication classes with approval by the U.S. … combinations for adults with type 2 diabetes.10, 11 Data on the newly-approved medication classes ( … We will not review these outcomes for any medication classes or comparisons except those including SGLT … Priority Medication Comparisons Included for Each Key Question Main Intervention Comparisons Source

247. Diabetes Medications for Adults with Type 2 Diabetes: An Update Focused on Monotherapy and Add-on Therapy to Metformin | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/diabetes-update-2015/research-protocol
     January 22, 2015 - Including insulin, there are 10 medication classes with approval by the U.S. … combinations for adults with type 2 diabetes. 10,11 Data on the newly-approved medication classes ( … We will not review these outcomes for any medication classes or comparisons except those including … Priority Medication Comparisons Included for Each Key Question Type of Therapy Main Intervention … We will then stratify studies by medication and repeat the pooled analyses and measures of heterogeneity

248. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
     December 01, 2010 - Outcomes: 1) Relapse and remission rates. 2) Medication adherence and persistent use (and associated … We will compare medication-associated adverse events in FGAs and SGAs (KQ3). … • Medication adherence and persistent use (associated dosing, time to discontinuation of treatment … to have experienced the event and the total number of patients in the medication groups in relevant … The dose of each medication that is associated with an adverse event will be recorded to facilitate

249. App-D-Surveillance-Report-1-Noninvasive-Nonpharm-Chronic-Pain (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surveillance-report-1-noninvasive-nonpharm-chronic-pain.xlsx
     January 01, 2021 - use: 56% vs. 47% RDQ (0–24) Pain intensity, Brief Pain Inventory (0–10) Opioid medication use Other … 0.11) vs. 0.15 (95% CI -0.18 to 0.47); between-group difference -0.59 (95% CI -1.05 to -0.13) Opioid medication … Participants reported standard sleep variables, and if they had used (yes/no) any form of medication, … including sleep and opioid medication. … Primary outcomes were yes/no use of sleep medication or opioids. 6 months Mean (SE) A vs.

250. App-D-Surv-Report-1-Noninvasive-Nonpharma (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-1-noninvasive-nonpharma.xlsx
     January 01, 2021 - use: 56% vs. 47% RDQ (0–24) Pain intensity, Brief Pain Inventory (0–10) Opioid medication use Other … 0.11) vs. 0.15 (95% CI -0.18 to 0.47); between-group difference -0.59 (95% CI -1.05 to -0.13) Opioid medication … Participants reported standard sleep variables, and if they had used (yes/no) any form of medication, … including sleep and opioid medication. … Primary outcomes were yes/no use of sleep medication or opioids. 6 months Mean (SE) A vs.

251. App-D-Surv-Report-1-Noninvasive-Nonpharma 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-1-noninvasive-nonpharma_0.xlsx
     January 01, 2021 - use: 56% vs. 47% RDQ (0–24) Pain intensity, Brief Pain Inventory (0–10) Opioid medication use Other … 0.11) vs. 0.15 (95% CI -0.18 to 0.47); between-group difference -0.59 (95% CI -1.05 to -0.13) Opioid medication … Participants reported standard sleep variables, and if they had used (yes/no) any form of medication, … including sleep and opioid medication. … Primary outcomes were yes/no use of sleep medication or opioids. 6 months Mean (SE) A vs.

252. App-D-Surv-Report-2-Noninvasive-Nonpharma (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-2-noninvasive-nonpharma.xlsx
     January 01, 2021 - use: 56% vs. 47% RDQ (0–24) Pain intensity, Brief Pain Inventory (0–10) Opioid medication use Other … 0.11) vs. 0.15 (95% CI -0.18 to 0.47); between-group difference -0.59 (95% CI -1.05 to -0.13) Opioid medication … Participants reported standard sleep variables, and if they had used (yes/no) any form of medication, … including sleep and opioid medication. … Primary outcomes were yes/no use of sleep medication or opioids. 6 months Mean (SE) A vs.

253. Evidence-based Practice Center Systematic Review Protocol - Management of Infantile Epilepsies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-disposition-comments.pdf
     October 25, 2022 - Those of us who treat patients with epilepsy recognize that medication toxicity and encephalopathy … Agree it is surprising there are no data on this medication, but this is common for first line medications … There is a distinction between an adverse event on a medication vs. ill effects or side effects that … Whelan, No affiliation listed Results Fifth: What is meant by "prior medication" (p. 43) as a source … Authors did not state specifically which baseline medication(s) had caused these eye abnormalities;

254. Cannabis-Annual-Update2-Table-E5 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-annual-update2-table-e5.xlsx
     March 13, 2023 - intensity, current and past pain medications, comorbidities, comedications, and reasons for switching medication … gender, pain severity, stage of chronification, history/duration of pain, comorbidity, concomitant medication … , prior medication, and baseline values A vs. … 0.14) vs. 0.07 (SD 0.27) Strong opioid analgesics: 0.22 (SD 0.59) vs. 0.21 (SD 0.60) Mean rescue pain medication

255. Cannabis-2022-Update-Surv-Rep-1-App-F-5 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F-5.xlsx
     January 01, 2022 - intensity, current and past pain medications, comorbidities, comedications, and reasons for switching medication … gender, pain severity, stage of chronification, history/duration of pain, comorbidity, concomitant medication … , prior medication, and baseline values A vs. … 0.14) vs. 0.07 (SD 0.27) Strong opioid analgesics: 0.22 (SD 0.59) vs. 0.21 (SD 0.60) Mean rescue pain medication

256. Cannabis-2022-Surv-Rep-3-Table-F5 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-table-F5.xlsx
     January 01, 2022 - intensity, current and past pain medications, comorbidities, comedications, and reasons for switching medication … gender, pain severity, stage of chronification, history/duration of pain, comorbidity, concomitant medication … , prior medication, and baseline values A vs. … 0.14) vs. 0.07 (SD 0.27) Strong opioid analgesics: 0.22 (SD 0.59) vs. 0.21 (SD 0.60) Mean rescue pain medication

257. Asthma-Immunotherapy-2010 Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_executive.pdf
     January 01, 2010 - use, and combined asthma plus rhinoconjunctivitis medication use. … The strength of evidence is low that subcutaneous immunotherapy reduces combined symptom-medication … symptom-medication scores. … plus symptom scores, conjunctivitis symptoms, and medication use, and improves quality of life. … plus symptom scores, conjunctivitis symptoms, medication use, and improves quality of life.

258. CER 173 Executive Summary: Diabetes Medications for Adults With Type 2 Diabetes: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
     January 01, 2015 - reduce diabetes complications.3-5 When beginning medical treatment, patients usually begin with a medication … Priority medication comparisons included for each Key Question Intervention Main Intervention Class … Interventions • We included studies that evaluated a diabetes medication of interest or drug combination … Weight Monotherapy and combination medication comparisons generally showed significant between-group … Medication use leading to emergency department visits for adverse drug events in older adults.

259. Newer Medications for Lower Urinary Tract Symptoms (LUTS) Associated with Benign Prostatic Hyperplasia (BPH) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/prostatic-hyperplasia-medications/research-protocol
     April 24, 2015 - . 6 Comparative effectiveness for combined AB/5-ARI therapy is superior to monotherapy with either medication … variety of medications available to treat LUTS/BPH, tailoring treatment with single medications or medication … Common medications used to treat LUTS associated with BPH Drug class Mechanism of action Medication … Comparators Placebo or other FDA approved medication ( Table 1 ) Outcomes Primary Outcomes … Adverse effects of intervention(s) Common and serious medication side effects Timing Short term

260. Mortality Risk in Chronic Obstructive Pulmonary Disease Patients Using Theophylline | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/copd-management/research
     December 04, 2009 - Two approaches were used, the first where treatment assignment was based on medication use at baseline