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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - Outcomes:
1) Relapse and remission rates.
2) Medication adherence and persistent use (and associated … We will compare medication-associated adverse events in FGAs and SGAs
(KQ3). … • Medication adherence and persistent use (associated dosing, time to
discontinuation of treatment … to have experienced the event and the total
number of patients in the medication groups in relevant … The dose of each
medication that is associated with an adverse event will be recorded to facilitate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_executive.pdf
January 01, 2010 - use, and combined asthma plus rhinoconjunctivitis
medication use. … The strength of evidence is low that subcutaneous
immunotherapy reduces combined symptom-medication … symptom-medication scores. … plus symptom scores, conjunctivitis symptoms,
and medication use, and improves quality of life. … plus symptom scores, conjunctivitis symptoms, medication
use, and improves quality of life.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - However, this makes it difficult to use the
information in determining whether a given medication is … more
or less likely to be associated with adverse effects than another
medication. … SNRI) were originally intended to identify
medication class effects, but that this was difficult due … It is
not clear why this medication was included in the review. … Peer reviewer
#6
Results As a general comment for the Key Points for each
medication/class, I found
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_executive.pdf
February 01, 2014 - We looked for data on the maintenance of remission
from inactive disease or response to a medication … Short-term adverse effects are events
that occur within 1 year of initiating a medication. … Long-
term adverse effects occur at least 1 year after initiating a
medication.
KQ4. … When a study compared multiple medication classes, our
report of the study begins with the first medication … Most of the observational
studies had no restrictions on previous medication use.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-rapid-research.pdf
April 01, 2025 - They created a reporting methodology to provide
daily updates of medication supply, usage rates, and … Pharmacists leadership in a medication
shortage response: Illustrative examples from
a health system … Pharmacists leadership in a medication
shortage response: Illustrative examples from
a health system … Low
efficacy of medication shortage clinical
decision support alerts. … Managing the
risk of shortages and medication errors with
curares during the COVID-19 pandemic: A
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
May 22, 2025 - Effects on ADHD Symptoms
18
Atomoxetine vs Methylphenidate
Medication vs Control
18
KQ2: Effects … of Medication Effects on Broadband Scales and Functional Impairment
19
Effects on Broadband Scales … Effects on Functional Impairment
19
KQ2: Effects of Medication on Appetite Suppression
20
Medication … Little evidence that combination therapies of medication plus psychosocial therapies produce better results … than medication alone, but existing research evaluated unique combinations of intervention components
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostatic-hyperplasia-medications_research-protocol.pdf
April 21, 2015 - variety of medications available to treat LUTS/BPH, tailoring
treatment with single medications or medication … adverse effects of one new AB (silodosin); all
anticholinergics, beta-2 agonists, and PDE-5s; and medication … Common medications used to treat LUTS associated with BPH
Drug class -
Mechanism of action Medication … Comparators
• Placebo or other FDA approved medication (Table 1)
Outcomes:
Primary Outcomes … Adverse effects of intervention(s) Common and serious medication side effects
Timing
Short term outcomes
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertensive-disorders-pregnancy-disposition-comments.pdf
May 31, 2023 - heart rate, edema,
biomarkers and comorbidities) that predict
a favorable response to a particular
medication … case finding (early
diagnosis), continuity and continued follow-up of care, affordability
of care, medication … adverse effects, medication compliance and
challenges in modifying lifestyle behavior. … purpose section page ES-2 paragraph 2
the new version does not mention or emphasize the importance
of medication … should
evaluate if comparative effectiveness
may be in part mediated by improved
adherence to a medication
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - disease in adults in the U.S.4 Costs related to diabetes
were approximately $245 billion in 2012.1
Medication … Including insulin, there are 10 medication classes with approval by the U.S. … combinations for adults with type 2 diabetes.10, 11 Data
on the newly-approved medication classes ( … We will not review these outcomes for
any medication classes or comparisons except those including SGLT … Priority Medication Comparisons Included for Each Key Question
Main Intervention Comparisons
Source
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-3-noninvasive-nonpharma_0.xlsx
January 01, 2022 - use: 56% vs. 47%
RDQ (0–24)
Pain intensity, Brief Pain Inventory (0–10)
Opioid medication use
Other … [Surveillance Report 1] China
1 center
Outpatient hospital Inclusion:
(a) without taking any other medication … Participants reported standard sleep variables, and if they had used (yes/no) any form of medication, … including sleep and opioid medication. … Primary outcomes were yes/no use of sleep medication or opioids. 6 months Mean (SE)
A vs.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-executive-summ.pdf
January 01, 2022 - The updated report now includes 125 pharmacologic studies
(trials with at least one medication arm) … and 312 nonpharmacologic studies (trials with no
medication arms).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_clinician.pdf
November 01, 2016 - cognitive behavioral therapy strategies); relaxation or stress
reduction; blood glucose regulation; medication … including
the disease process, treatment options, nutritional
management, physical activity, safe medication
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_research-protocol.pdf
June 05, 2014 - factors contributing to optimal
diabetes care and self-management including lifestyle behaviors and medication … .19 For many, a key behavior may be self-regulation of
carbohydrate intake, physical activity and/or medication … cognitive behavioral therapy strategies); relaxation or stress reduction; blood
glucose regulation; medication … This includes self-regulation of medication, diet, physical activity
and so forth, based on results … Self Medication/
31. Self Care/
32. Weight Loss/
33. (behavio?r adj2 therap*).mp.
34.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2010_research-protocol.pdf
January 01, 2010 - and environmental control, who cannot tolerate their medications, or who do not comply with chronic
medication … usage scores
c) Combined symptom + medication diary scores
d) Quality of life
Rhinoconjunctivitis … score
c) Combined asthma symptom-medication scores
Additional Secondary Endpoints:
Source … Allergic asthma is
airway obstruction and inflammation that is partially reversible with medication … b) Medication diary scores: For example: In the diaries participants recorded morning and evening peak
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
November 21, 2011 - , excluding regular cyclic/menstrual patterns of bleeding, fibroids,
polyps, adenomyosis, cancers, medication … excluding irregular and unpredictable patterns of bleeding,
fibroids, polyps, adenomyosis, cancers, medication … menstrual patterns of bleeding and
bleeding associated with fibroids, polyps, adenomyosis, cancer, medication … thyroid disease,
coagulopathy), structural abnormalities (e.g., fibroids, adenomyosis), cancer,
or medication … excluding regular cyclic/menstrual patterns of bleeding, fibroids, polyps,
adenomyosis, cancers, medication
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
January 01, 2007 - interventions—including diet, exercise, and
control of body weight—many individuals
will require antihypertensive medication … addition of a second agent to an ARB
was heavily influenced by retrospective cohort studies,
where medication … discontinuation rates were higher in
ACEI-treated patients, and by RCTs with very loosely
defined protocols for medication
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - it
may help policymakers and insurers to have better
insight when deciding on policies relating to medication … Meta-regression was
conducted using study-level characteristics such as dose
of medication, study duration … In each column of
the summary table, we indicate the medication that had
a better effect on the listed … For Key Question 6 (differences across
specific populations)
To determine differences in medication … In terms of safety, each medication was
associated with specific adverse events, although
thiazolidinediones
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pilot-projects-supplementing-white-paper.pdf
December 01, 2024 - during
systematic reviews
related to outcomes of
neurosurgery for
epilepsy including safety
and medication … • Patient data were joined using unique
identifiers to medication, procedure, office
encounter, … Determined proportion not taking bone protective medication (BPM) at admission; compared with recent … also explored what percentage of patients with incident hip fracture were
not taking bone protective medication … analysis identified a large
proportion of hip fracture patients who were not taking bone protective medication
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
April 01, 2013 - for weight control), and only a few studies
evaluated hypoglycemic medication.
7
Key Question 1 … • No studies evaluated the weight loss medication orlistat
in this population. … No
studies evaluated orlistat, an FDA-approved medication
for the treatment of obesity that is also … The experimental
intervention was psychotropic medication in three
trials, antipsychotic switching … Guideline
concordant monitoring of metabolic risk in people treated with
antipsychotic medication:
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveill-report-1.xlsx
September 30, 2015 - medical stable (COWS score ≤5, no acute opioid withdrawal); resident of one of two counties; presence of medication … prisoners); co-occurring psychiatric disorder; cardiac or pulmonary issues; homeless or on parole; current medication … functioning, depression, or drug use Harms not reported by treatment group
Suspected abuse of study medication … enhanced Charlson comorbidity score; diagnoses for chronic non-cancer pain and mental health conditions; medication