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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
    December 01, 2010 - Outcomes: 1) Relapse and remission rates. 2) Medication adherence and persistent use (and associated … We will compare medication-associated adverse events in FGAs and SGAs (KQ3). … • Medication adherence and persistent use (associated dosing, time to discontinuation of treatment … to have experienced the event and the total number of patients in the medication groups in relevant … The dose of each medication that is associated with an adverse event will be recorded to facilitate
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_executive.pdf
    January 01, 2010 - use, and combined asthma plus rhinoconjunctivitis medication use. … The strength of evidence is low that subcutaneous immunotherapy reduces combined symptom-medication … symptom-medication scores. … plus symptom scores, conjunctivitis symptoms, and medication use, and improves quality of life. … plus symptom scores, conjunctivitis symptoms, medication use, and improves quality of life.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
    March 28, 2019 - However, this makes it difficult to use the information in determining whether a given medication is … more or less likely to be associated with adverse effects than another medication. … SNRI) were originally intended to identify medication class effects, but that this was difficult due … It is not clear why this medication was included in the review. … Peer reviewer #6 Results As a general comment for the Key Points for each medication/class, I found
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_executive.pdf
    February 01, 2014 - We looked for data on the maintenance of remission from inactive disease or response to a medication … Short-term adverse effects are events that occur within 1 year of initiating a medication. … Long- term adverse effects occur at least 1 year after initiating a medication. KQ4. … When a study compared multiple medication classes, our report of the study begins with the first medication … Most of the observational studies had no restrictions on previous medication use.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-rapid-research.pdf
    April 01, 2025 - They created a reporting methodology to provide daily updates of medication supply, usage rates, and … Pharmacists leadership in a medication shortage response: Illustrative examples from a health system … Pharmacists leadership in a medication shortage response: Illustrative examples from a health system … Low efficacy of medication shortage clinical decision support alerts. … Managing the risk of shortages and medication errors with curares during the COVID-19 pandemic: A
  6. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
    May 22, 2025 - Effects on ADHD Symptoms 18 Atomoxetine vs Methylphenidate Medication vs Control 18 KQ2: Effects … of Medication Effects on Broadband Scales and Functional Impairment 19 Effects on Broadband Scales … Effects on Functional Impairment 19 KQ2: Effects of Medication on Appetite Suppression 20 Medication … Little evidence that combination therapies of medication plus psychosocial therapies produce better results … than medication alone, but existing research evaluated unique combinations of intervention components
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostatic-hyperplasia-medications_research-protocol.pdf
    April 21, 2015 - variety of medications available to treat LUTS/BPH, tailoring treatment with single medications or medication … adverse effects of one new AB (silodosin); all anticholinergics, beta-2 agonists, and PDE-5s; and medication … Common medications used to treat LUTS associated with BPH Drug class - Mechanism of action Medication … Comparators • Placebo or other FDA approved medication (Table 1) Outcomes: Primary Outcomes … Adverse effects of intervention(s) Common and serious medication side effects Timing Short term outcomes
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertensive-disorders-pregnancy-disposition-comments.pdf
    May 31, 2023 - heart rate, edema, biomarkers and comorbidities) that predict a favorable response to a particular medication … case finding (early diagnosis), continuity and continued follow-up of care, affordability of care, medication … adverse effects, medication compliance and challenges in modifying lifestyle behavior. … purpose section page ES-2 paragraph 2 the new version does not mention or emphasize the importance of medication … should evaluate if comparative effectiveness may be in part mediated by improved adherence to a medication
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
    January 01, 2015 - disease in adults in the U.S.4 Costs related to diabetes were approximately $245 billion in 2012.1 Medication … Including insulin, there are 10 medication classes with approval by the U.S. … combinations for adults with type 2 diabetes.10, 11 Data on the newly-approved medication classes ( … We will not review these outcomes for any medication classes or comparisons except those including SGLT … Priority Medication Comparisons Included for Each Key Question Main Intervention Comparisons Source
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-3-noninvasive-nonpharma_0.xlsx
    January 01, 2022 - use: 56% vs. 47% RDQ (0–24) Pain intensity, Brief Pain Inventory (0–10) Opioid medication use Other … [Surveillance Report 1] China 1 center Outpatient hospital Inclusion: (a) without taking any other medication … Participants reported standard sleep variables, and if they had used (yes/no) any form of medication, … including sleep and opioid medication. … Primary outcomes were yes/no use of sleep medication or opioids. 6 months Mean (SE) A vs.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-executive-summ.pdf
    January 01, 2022 - The updated report now includes 125 pharmacologic studies (trials with at least one medication arm) … and 312 nonpharmacologic studies (trials with no medication arms).
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_clinician.pdf
    November 01, 2016 - cognitive behavioral therapy strategies); relaxation or stress reduction; blood glucose regulation; medication … including the disease process, treatment options, nutritional management, physical activity, safe medication
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_research-protocol.pdf
    June 05, 2014 - factors contributing to optimal diabetes care and self-management including lifestyle behaviors and medication … .19 For many, a key behavior may be self-regulation of carbohydrate intake, physical activity and/or medication … cognitive behavioral therapy strategies); relaxation or stress reduction; blood glucose regulation; medication … This includes self-regulation of medication, diet, physical activity and so forth, based on results … Self Medication/ 31. Self Care/ 32. Weight Loss/ 33. (behavio?r adj2 therap*).mp. 34.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2010_research-protocol.pdf
    January 01, 2010 - and environmental control, who cannot tolerate their medications, or who do not comply with chronic medication … usage scores c) Combined symptom + medication diary scores d) Quality of life Rhinoconjunctivitis … score c) Combined asthma symptom-medication scores Additional Secondary Endpoints: Source … Allergic asthma is airway obstruction and inflammation that is partially reversible with medication … b) Medication diary scores: For example: In the diaries participants recorded morning and evening peak
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
    November 21, 2011 - , excluding regular cyclic/menstrual patterns of bleeding, fibroids, polyps, adenomyosis, cancers, medication … excluding irregular and unpredictable patterns of bleeding, fibroids, polyps, adenomyosis, cancers, medication … menstrual patterns of bleeding and bleeding associated with fibroids, polyps, adenomyosis, cancer, medication … thyroid disease, coagulopathy), structural abnormalities (e.g., fibroids, adenomyosis), cancer, or medication … excluding regular cyclic/menstrual patterns of bleeding, fibroids, polyps, adenomyosis, cancers, medication
  16. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
    January 01, 2007 - interventions—including diet, exercise, and control of body weight—many individuals will require antihypertensive medication … addition of a second agent to an ARB was heavily influenced by retrospective cohort studies, where medication … discontinuation rates were higher in ACEI-treated patients, and by RCTs with very loosely defined protocols for medication
  17. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - it may help policymakers and insurers to have better insight when deciding on policies relating to medication … Meta-regression was conducted using study-level characteristics such as dose of medication, study duration … In each column of the summary table, we indicate the medication that had a better effect on the listed … For Key Question 6 (differences across specific populations) To determine differences in medication … In terms of safety, each medication was associated with specific adverse events, although thiazolidinediones
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pilot-projects-supplementing-white-paper.pdf
    December 01, 2024 - during systematic reviews related to outcomes of neurosurgery for epilepsy including safety and medication … • Patient data were joined using unique identifiers to medication, procedure, office encounter, … Determined proportion not taking bone protective medication (BPM) at admission; compared with recent … also explored what percentage of patients with incident hip fracture were not taking bone protective medication … analysis identified a large proportion of hip fracture patients who were not taking bone protective medication
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
    April 01, 2013 - for weight control), and only a few studies evaluated hypoglycemic medication. 7 Key Question 1 … • No studies evaluated the weight loss medication orlistat in this population. … No studies evaluated orlistat, an FDA-approved medication for the treatment of obesity that is also … The experimental intervention was psychotropic medication in three trials, antipsychotic switching … Guideline concordant monitoring of metabolic risk in people treated with antipsychotic medication:
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveill-report-1.xlsx
    September 30, 2015 - medical stable (COWS score ≤5, no acute opioid withdrawal); resident of one of two counties; presence of medication … prisoners); co-occurring psychiatric disorder; cardiac or pulmonary issues; homeless or on parole; current medication … functioning, depression, or drug use Harms not reported by treatment group Suspected abuse of study medication … enhanced Charlson comorbidity score; diagnoses for chronic non-cancer pain and mental health conditions; medication

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