-
effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
October 01, 2007 - Measures: Exposure to statin therapy was assessed at the beginning
of follow-up with all cohort members … Lipoprotein measures
(LDL, HDL, and TG) were assumed to be valid for up to 6
months from the date of … We found that measures of healthcare utilization (in-
tensities of lipid-related laboratory testing, … chronic therapy as well as the
physician’s urgency in recommending a therapy will be
reflected in these measures
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_executive.pdf
October 01, 2012 - Among four other morbidity measures the evidence
was insufficient.
7
Evidence on dementia SCUs … Low
New/worsening
morbidity and various
discrete measures
Morbidity across multiple measures differed … Many
studies in this review used the CMAI (the Cohen
Mansfield Agitation Inventory, a measure of behavioral … symptoms),20-23 and other established measures are
available for other outcomes of interest. … • Use established outcome measures to enable the
pooling of data or qualitative interpretations.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
September 25, 2013 - Definitions, outcome measures
and statistical methods are appropriate. … The outcome measures used for this topic are quite
complicated with several of them relying on epidemiological … Analytic sensitivity and specificity are used in the
characterization of tests that measure levels of … identifies 40 studies that examined the
association of genotype results with platelet reactivity
measures … Teirstein
Results Platelet reactivity should be considered a viable surrogate
outcome measure.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-rapid-research.pdf
May 01, 2025 - event
Secondary outcomes:
• Intermediate outcomes
related to embedding HRO
principles, e.g., measures … the review questions, and included author, year, study design, frequency and severity
of the harms, measures … characteristics
Author,
Year
Study
Design
Setting HRO
Framework
HRO Activities*
Primary Outcome
Measures … Secondary
Outcome
Measures
Sculli,
202215
Pre-post
Compare
d to all
VHA
facilities
(All … Developing well defined structural
measures to guide implementation would be a potential strategy to
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-update_research-protocol.pdf
June 15, 2016 - in
Rheumatology) has developed guidelines on outcome measures.24
General tools that have been adapted … Studies of similar interventions will be grouped by outcome measures if
feasible. … However, if most studies that report on a common outcome report different
measures, we will conduct … Knee Injury and Osteoarthritis Outcome
Score (KOOS)--development of a self-
administered outcome measure … Development and Validation of the
Computer-Administered Animated Activity
Questionnaire to Measure
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - GRADE Approaches to Evaluating Evidence
The EPCs’ strength of evidence approach is based in large measure … For example, studies in a review may use a variety
of scales to measure the same outcome, and those … Moreover, some or all of such scales may not have been
subjected to reliability or validity testing. … Thus, EPCs may not be able to determine a meaningful
threshold across scales with different measurement … because of potential problems in their interpretation and lack of
statistical power.45,46 No single measure
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-apbi-breast-cancer.pdf
August 01, 2022 - Group scores and Late Effects
Normal Tissue Task Force--
Subjective, Objective,
Management, Analytic scales … scores and
Late Effects Normal Tissue
Task Force-- Subjective,
Objective, Management,
Analytic scales … Homogeneity of variance of measures associated with objective assessment of
esthetic outcome after treatment … There are
several groups that regularly measure patterns of care and publish on adherence with ASTRO … ASTRO will collaborate and support patterns of care studies to measure and compare
rates of concordance
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-literacy_research-protocol.pdf
January 22, 2010 - The assessment included items
intended to directly measure health literacy. … Measures of disease incidence, prevalence, morbidity, and mortality. … Low parental literacy is associated with worse
asthma care measures in children. … Testing the feasibility of an interactive learning
styles measure for U.S. … Agreement between scales in the measurement of
breast cancer risk perceptions.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
April 01, 2013 - Weights are based on the rank numbers (1–12) of each gap multiplied by how many stakeholders assigned … Short-term
quality of
life
Nine studies found an SVR associated with greater
improvement in measures … a Weights are based on the score (high=3, medium=2, low=1) multiplied by the number of stakeholder endorsements … a Weights are based on the rank numbers (1-12) of each gap multiplied by how many stakeholders assigned … treatment and post-
treatment
D-5
NCT Number Study Titles Interventions
Age
Groups Outcome Measures
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
February 01, 2012 - Secondly, it does not measure any health-related outcomes that would help deduce
which AHI measurements … The proper outcome
measure is quality-adjusted life-years (QALYs) gained. … survey respondents’ answer to favor sleep specialists or nonspecialists with respect to any
outcome measure … vs. high), the (predictive) sensitivity and the (predictive) specificity of a CPR would be a
way to measure … (which are quick and easy to collect), symptoms (e.g., sleepiness scales), clinical
outcomes (e.g.,
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
January 12, 2022 - determining which outcomes to assess and challenges in assessing them (e.g., use of
multiple instruments to measure … (e.g., VAS, NRS,
NDI, SF-36, SF-12, EQ-5Dm, mJOA
score, Nurick score, MDI, PROMIS-29,
dysphagia scales … We will classify the magnitude of effects for continuous measures of pain
and function using a similar … For analysis of continuous measures
11
across the same … for outcomes measures with similar constructs
together with 95% confidence intervals.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_executive.pdf
October 01, 2010 - Treatment advances in CF over the past 25
years have improved measures of nutrition,
pulmonary function … It has been investigated for
the treatment of CF because of the decreased growth
measures and increased … The link
between different measures of weight and mortality was
supported in a majority of studies that … between pulmonary function and
HRQoL in patients with CF was evaluated in 14
studies, but 10 different scales … between anthropometrics and HRQoL
in patients with CF was evaluated in 10 studies, but
nine different scales
-
effectivehealthcare.ahrq.gov/sites/default/files/covariate-selection-chapter-7.pptx
January 01, 2013 - adherence, and a newer class of causal effect estimators, such as inverse probability of treatment weights … Inverse probability-of-censoring weights for the correction of time-varying noncompliance in the effect
-
effectivehealthcare.ahrq.gov/sites/default/files/masks-surveillance-2-appendix-table-a-3.xlsx
March 23, 2020 - reported Potential recall bias; 60% of eligible cases included
Chen W et al. 2009 Which preventive measures … controls were exposed to SARS-1 patients but otherwise not matched; collinearity in model not addressed
Scales … SARS; collinearity in model not addressed
Yin W et al. 2004 [Effectiveness of personal protective measures
-
effectivehealthcare.ahrq.gov/sites/default/files/Masks-appendix-table-b-3-surveillance-report.xlsx
February 01, 2020 - ; analyses appear to exclude 2 patients with subclinical SARS-1
Chen W et al 2009 Which preventive measures … controls were exposed to SARS-1 patients but otherwise not matched; collinearity in model not addressed
Scales … probable SARS; collinearity in model not addressed
Yin W et al 2004 [Effectiveness of personal protective measures
-
effectivehealthcare.ahrq.gov/sites/default/files/masks-appendix-table-b-3-version-2.xlsx
February 01, 2020 - ; analyses appear to exclude 2 patients with subclinical SARS-1
Chen W et al 2009 Which preventive measures … controls were exposed to SARS-1 patients but otherwise not matched; collinearity in model not addressed
Scales … probable SARS; collinearity in model not addressed
Yin W et al 2004 [Effectiveness of personal protective measures
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
October 08, 2014 - Compared with the immunoassays, HPLC and
LC-MS/MS offer more precise measures of the parent compound … In the absence of such studies, we will include as indirect
evidence studies that report measures of … We will compute effect sizes and measures of variance using standard methods and will
perform random-effects … Was the outcome measure of interest objective and was it objectively measured?
18. … Was a standard instrument used to measure the outcome?
19.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
December 27, 2016 - increasing the dose of ICS that is otherwise taken as controller therapy, either
strategy in response to a measure … • Asthma Control
o Composite Measures
Source: www.effectivehealthcare.ahrq.gov
Published online … interventions (e.g. intervention drug(s), comparison, dose,
frequency, concomitant medications), outcome measures … , and the results of each
outcome, including measures of variability. … self-reported symptoms, nighttime
awakenings, rescue SABA use, interference with normal activities; objective measures
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research-protocol.pdf
September 02, 2016 - September 2, 2016
3
• Number of study arms
• Intervention description
• Study design
• Outcomes measures … ] Methods: primary outcome measure M/D/P
[Primary outcome measure] Results: All planned timepoints reported … M/D/P
[Secondary outcome measure] Results: secondary outcome-1 reported M/D/P
[Secondary outcome measure … ] Results: secondary outcome-2 reported M/D/P
[Secondary outcome measure] Results: secondary outcome … outcome measure] Results: secondary outcome-5 reported M/D/P
[Secondary outcome measure] Results: secondary
-
effectivehealthcare.ahrq.gov/sites/default/files/mcda-johnson.pdf
August 27, 2012 - Choice
Example
Instruments
SF-36 EQ-5D Tariffs Tailored
Metrics HRQoL Scores QALYs Preference
Weights … , HTE,
MAR, MAB,
WTP
Uses CEA, licensing CEA,
reimbursement
Preference
Weights, HTE,
MAR, MAB … Statistical model estimates preference weights consistent with observed choices. … Preference weights quantify relative importance as the willingness to accept
tradeoffs. … Idea of treating patient-preference measures as evidence is novel for most
clinicians.