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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
    December 01, 2017 - Throughout this report, we refer to whether or not a study assessed change in specific measures including … One study reported a four percent reduction in size and those that reported volume measures documented … Studies consistently reported significant improvement in measures of quality of life symptoms (days … Four studies reporting the outcome consistently noted significant improvements in quality of life measures … Little continuity exists in approaches to measuring outcomes and use of unvalidated measures is common
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
    July 01, 2012 - medical tests; however, there is no empirical evidence that any sort of score based on quantitative weights … can be addressed when considering all relevant studies through the use, if appropriate, of a summary measure … West et al.7 evaluated 18 tools (six scales, nine guides, and three EPC rating systems). … Three scales met all six criteria considered important: (1) the Cochrane Working Group checklist,8 ( … In 5-6 this way, reviewers can revise unreliable terms and measure the reliability of the ultimate
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
    June 15, 2011 - reviews also left unresolved the potential impact of patient demographics, comorbidities, biochemical measures … different dietary and pharmacological preventive treatments; the value of urine and blood biochemical measures … were added to address whether the efficacy of therapies differs according to baseline biochemical measures … whether the efficacy of therapies as measured by stone outcomes correlates with followup biochemical measures … treatment differ according to patient baseline stone composition and blood and urine biochemical measures
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-1-year-final-report-updated-title_0.pdf
    May 01, 2024 - o Future research should measure outcomes and unintended consequences in the same study to generate … primary recommendations for future research were studies with stronger designs and better outcome measures … ; and (3) multicomponent sepsis interventions showed improvement in at least one process measure, but … only two studies showed improvement in outcome measures. 5b. … primary recommendations for future research were studies with stronger designs and better outcome measures
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_disposition-comments.pdf
    November 07, 2012 - Although the time commitment is challenging to measure the burden of family care, more work should be … The MDS 3.0 includes some resident report measures. … The choice of and rationale for outcome measures is clear, and the discussion of outcome measures is … It is not clear why this was not included as an outcome measure. … The paper only addresses per user costs, which is the least important measure.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_disposition-comments.pdf
    May 20, 2013 - No studies directly assessed using capsule internationally or in a community- based environment to measure … No mention that ROM fails to even measure colonic transit and that it lacks indication of severity. … As a result, WMC indirectly measures what GES measures but also measures another factor which can contribute … In a sense, then, wireless motility capsule indirectly measures what gastric scintigraphy measures. … The diagnostic tests measure different physiologic mechanisms, emptying of a low fat meal compared
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
    June 24, 2014 - of treatment differ according to patient baseline uric acid levels and blood and urine biochemical measures … gout being treated to prevent gout recurrence, do results of follow-up blood and urine biochemistry measures
  8. effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
    April 01, 2016 - intervention and combined social and physical environment intervention) and the control group on any measure … Future studies should also consider direct measures of worker health if possible. … For example, investigators should try to use validated measures of health status, functional status … Researchers should measure the incidence or morbidity associated with chronic diseases when feasible … of variance (e.g., confidence intervals) for outcome measures.
  9. effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
    January 01, 2013 - will: Propose and describe planned sensitivity analyses Describe important subpopulations in which measures … several cases where it is possible that the effectiveness of specific therapies can be subject to effect measure … confidence in applying the results uniformly to all subpopulations and may highlight the presence of effect measure … Assess expected impact of unmeasured confounders on key measures of association. … Describe important subpopulations in which measures of effect will be assessed for homogeneity.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-app-e.xlsx
    January 01, 2021 - Outcome and Confounder Measures Reliable and Implemented Consistently Across Groups? … Valid and Reliable Measures Used and Adequately Ascertained? … Valid and Reliable Measures Used and Adequately Ascertained?
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
    December 23, 2014 - Do performance measures vary with sample characteristics? c. … Studies that do not report CDI incidence rates and tie incidence to the intermediate process measures … appropriateness of pooling data.38 We will assess statistical heterogeneity with Cochran’s Q test and measure … Yes Valid measures, groups ~equivalent No Non-validated measures or nonequivalent groups Uncertain … Yes Measures were valid and reliable (i.e., objective measure, validated scale/tool); consistent
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-heart_research-protocol.pdf
    April 18, 2012 - We will summarize binary or categorical outcomes (e.g., smoking status) by weighted effect measure for … using different scales, we will use standard mean differences. … mesh] OR overweight[tiab] OR obesity[mesh] OR obesity[tiab] OR obese[tiab] OR weight[tiab] OR Body weightsand measures[mesh] OR "body mass index"[tw] OR bmi[tw] 824293 #3 chlorpromazine[MeSH] OR chlorpromazine … presenting physical function/ health-related quality of life outcomes to also provide data for a CV risk measure
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
    May 01, 2013 - each outcome, including measures of variability. … No study reported a measure of weight, blood sugar, or smoking status at baseline. … scintigraphy Motility assessment: pressure patterns Low 3 WMC can measure pressure patterns and … (Scintigraphy does not measure pressure patterns.) … In a sense, then, WMC indirectly measures what gastric scintigraphy measures.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01_0.pdf
    May 01, 2005 - measurement bias; outcomes measures) measures) specifically validity, reliability, and variation … Choice of Outcome Measures The use of valid and reliable outcome measures reduces the likelihood of … risk reduction; selecting from multiple 9 endpoints47 or reporting on subscales of larger scales … Though the use of quantitative scales is a way to employ a transparent set of results, any weighting … Scales to assess the quality of randomized controlled trials: a systematic review.
  15. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
    June 01, 2011 - No differences were found between ACEIs and ARBs in ARB); measures of general quality of life; this is … disease-specific). • Morbidity (especially major cardiovascular events [myocardial infarction (MI), stroke] and measures … hemoglobin [HbA1c], dosage of insulin or other diabetes medication, fasting plasma glucose, or aggregated measures … of serial glucose measurements). • Measures of left ventricular mass/function (left ventricular mass … index and ejection fraction). • Measures of kidney disease (creatinine/glomerular filtration rate [GFR
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
    August 27, 2012 - TEP #5 Discussion/ Conclusions 1) you say the ABC is the "best" outcome measure in terms of reliability … TEP #1 Discussion/ Conclusion My concern with the statement about outcome measures is that although … 28 of 31 studies may have employed "valid outcome measures," questions remain about the appropriateness … of some measures to really measuring meaningful outcomes in adolescents and adults. … As a rule, manuals on which to base fidelity measures are not available for these programs.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
    December 14, 2010 - Outcome measures for harms, or adverse events, are the same as in KQ3, and KQ5 below. … the selection based on their professional knowledge and also considering the frequency of an outcome measure … To arrive at a quantitative measure for controlled trials, we will use the Jadad scale, which was developed … For subgroups where pooling is done across several scales, we will calculate an unbiased estimate using … Since most of the scales used as outcome measures in the pooled analyses are scored so that more severely
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
    January 01, 2012 - Studies generally prespecify and measure benefit outcomes with great reliability. … As a consequence, no measures of uncertainty are available. … Systematic reviews often use NNT and NNH as a measure of benefit and harm. … Benefits and harms may be reported on different scales. … The number needed to treat: a clinically useful measure of treatment effect.
  19. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
    April 01, 2007 - to determine clinical effectiveness or cost effectiveness of health care products and services, to measure … or monitor safety and harm, and/or to measure quality of care. … In choosing measurement scales for assessing patient-reported outcomes, it is preferable to use scales … • Measuring or improving quality of care, including conducting programs to measure and/or improve the … that can be confirmed by an unbiased observer—such as death, test results, and scores from validated measures
  20. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
    May 01, 2005 - measurement bias; outcomes measures) measures) specifically validity, reliability, and variation … Choice of Outcome Measures The use of valid and reliable outcome measures reduces the likelihood of … risk reduction; selecting from multiple 9 endpoints47 or reporting on subscales of larger scales … Though the use of quantitative scales is a way to employ a transparent set of results, any weighting … Scales to assess the quality of randomized controlled trials: a systematic review.

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