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1681. Disposition of Comments for CER 163 Appropriate Antibiotics (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
      January 27, 2016 - This then leads onto concerns about the interventions and outcome measures. … Most of the studies included do not measure this. 5. … Definitions and criteria were stated, when applicable, as were outcome measures (though many interim … Are the definitions or diagnostic criteria for the outcome measures appropriate? … The definitions or diagnostic criteria for all of the outcome measures also seem appropriate although

1682. Contrast-Induced Nephropathy (CIN): Current State of the Evidence on Contrast Media and Prevention of CIN (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
      August 01, 2016 - The other review assessed the evidence regarding the comparative efficacy of measures to prevent CIN … published in December 2015) and Contrast-Induced Nephropathy: Comparative Effectiveness of Preventive Measures

1683. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
      November 22, 2011 - ticagrelor) can overcome the effects of genotype on platelet reactivity. 15-17 Phenotypic testing measures … We refer to all these assays as “phenotypic tests,” because they attempt to measure an intermediate … Results include metrics of analytic validity (e.g., sensitivity, specificity, measures of variability … : Analytic validity refers to the technical performance of a test—that is, how well does the test measure … what it is designed to measure?

1684. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
      August 10, 2010 - will include the type of instrument or scale, primary or secondary outcome status, type of effect measure … (endpoint or change score, measure of variance (standard deviation, standard error, etc), and definition … based on clinical judgment with regards to comparability of study populations, treatments, and outcome measures … and outcome characteristics (e.g., long-term follow-up vs. short-term follow-up; different measuring scales

1685. Interventions Targeting Sensory Challenges in Children With Autism Spectrum Disorders - An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-interventions-disposition.pdf
      May 26, 2017 - There is a validated fidelity measure to evaluate whether an intervention adheres to Ayres Sensory … TEP Reviewer #1 Methods The definitions of outcome measures described risk of bias assessment of … al, 2014 study showed improvements in social skills and self care skills using a validated outcome measure … We re-examined the data for these studies and determined that the outcome measures were too disparate … 2011 found statistically significant improvements in individual goals (measured by goal attainment scales

1686. Pressure-Ulcer-Treatment Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
      May 01, 2013 - Outcomes The most commonly examined outcomes were measures of wound improvement. … Some studies used composite outcome measures commonly employed to monitor pressure ulcer status. … When meta-analysis was conducted, we used relative risk as the effect measure. … Although wound size reduction is a reasonable measure of therapeutic effect, in clinical practice the … Another major limitation of the evidence base relates to the most common outcome measure: wound size

1687. Topic 0614 Tonsillectomy NSD FINAL CC (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0768-141211.pdf
      October 23, 2014 - recommendation of tonsillectomy in children with recurrent throat infection stems from the varied measures

1688. An analytical framework for quantifying components of variability in prescriber decisions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
      April 01, 2010 - estimator can also be interpreted as a weighted average of subgroup- specific treatment effects where the weights … Conversely, overuse up-weights treatment effects in low-risk patients and thus may cause an IV estimator … estimator can be interpreted as a weighted average of subgroup- specific treatment effects in which the weights … Instrument relevance in multivariate linear models: a simple measure. … Dichotomous Outcomes and Relative Measures of Effect.

1689. Disposition of Comments for CERs 155 156 Contast-Induced Nephropathy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
      January 07, 2016 - Report Research Review Titles: Contrast-induced Nephropathy: Comparative Effectiveness of Preventive Measures … Contrast-Induced Nephropathy: Comparative Effectiveness of Preventive Measures. … How does the comparative effectiveness of prevention measures vary by patient characteristics; b. … How does the comparative effectiveness of prevention measures vary according to the type of contrast … was measured at four hours, and was insignificant at 48 hours, which was the time frame for the measure

1690. Fibromyalgia Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
      January 01, 2015 - eliminated the criterion of tender points examination and added (1) physician-rated severity on two scales … difference in mean change from baseline between treated and control groups by subgroup strata as a general measure … Multiple measures 11 for pain were used. … Fibromyalgia criteria and severity scales for clinical and epidemiological studies: a modification … A comparative study of patients with and without abnormality in (MMPI) psychological scales.

1691. Pharmacologic and Nonpharmacologic Treatments of Post-Traumatic Stress Disorder (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol.pdf
      July 10, 2018 - Primary PTSD outcome measure (if not reported, assume clinician-rated PTSD measure) w. … All other outcome measures (list) x. Assessment time points for primary PTSD outcome y. … Method for handing missing data for primary PTSD outcome measure d. … Results for primary PTSD outcome measure e. … Results for other PTSD outcome measure h.

1692. Pharmacologic and Nonpharmacologic Treatments of Post-Traumatic Stress Disorder (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-protocol.pdf
      July 10, 2018 - Primary PTSD outcome measure (if not reported, assume clinician-rated PTSD measure) w. … All other outcome measures (list) x. Assessment time points for primary PTSD outcome y. … Method for handing missing data for primary PTSD outcome measure d. … Results for primary PTSD outcome measure e. … Results for other PTSD outcome measure h.

1693. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
      January 01, 2017 - including suicide and suicide attempts • Improvements in health-related quality of life (using validated scales … studies also reported no difference in improvement in core illness symptoms, measured by symptoms scales … • Measure key health outcomes, using agreed-upon direct measures. … For example, measuring functional outcomes using not only valid and reliable scales, but also actual … measures of patient functioning.

1694. Disposition of Comments Report for Evaluation and Treatment of Tinnitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_disposition-comments.pdf
      August 23, 2013 - (i.e., otolaryngologist, audiologist, neurologist, mental health professional); administration of scales … However, both of these scales are considered to be reliable and valid and are widely used. … Subjective measures of loudness were retained as eligible outcome measures because they were felt to … for any studies that used the terms ‘discomfort’, ‘annoyance’ or ‘distress’ to describe an outcome measure … The primary reasons they were excluded is that the studies did not present a measure of variance around

1695. Untitled (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
      December 04, 2015 - For continuous outcomes measures, we will extract (by arm) the mean baseline and endpoint or change … scores, standard deviations (SD) or other measure of variability, and number analyzed. … For quality of life and other continuous patient/parent/clinician-reported measures, we will use an … clinically important benefit and harm, as suitable to the measure.51 For other outcomes, we will seek … (e.g., aggression scales or subscales) if the scales are considered to measure the same construct;

1696. Assessing the Quality of Individual Studies (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/assessing-quality.ppt
      January 01, 2010 - Result from problems in data analysis and interpretation, such as choice of the wrong statistical measure … Did investigators concurrently measure intervention and exposure status for intervention and comparison … Did investigators concurrently measure outcomes for intervention and comparison groups?