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srdr.ahrq.gov/projects/1565/studies/189285
January 01, 2018 - Key Questions Addressed
2
KQ 2: What is the evidence that apnea and hypopnea-based measures … and apnea-hypopnea indices) used in current practice and research are valid surrogate or intermediate measures … Follow Up
Answer
Follow-up Answer
Measure(s) being evaluated) … 29.8
Within-Arm Comparisons
Comparison
Measure …
Population: All Participants
Time Point
Measure
No active treatment
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srdr.ahrq.gov/projects/1312/studies/133123
January 01, 2015 - Outcome: Myocardial infarction
Population: All Participants
Time Point
Measure … Outcome: Vascular diseases
Population: All Participants
Time Point
Measure … Outcome: Cardiac death
Population: All Participants
Time Point
Measure … Outcome: rehospitalization
Population: All Participants
Time Point
Measure … Outcome: Vascular diseases
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1312/studies/133191
January 01, 2007 - Outcome: Systolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Diastolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Triglycerides
Population: All Participants
Time Point
Measure … Outcome: Total cholesterol
Population: All Participants
Time Point
Measure … Outcome: Fasting blood glucose
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1312/studies/133220
January 01, 2014 - Outcome: Total cholesterol
Population: All Participants
Time Point
Measure … Outcome: Triglycerides
Population: All Participants
Time Point
Measure … Outcome: hsCRP or hs-CRP
Population: All Participants
Time Point
Measure … Outcome: Interleukin-6 (IL-6)
Population: All Participants
Time Point
Measure … necrosis factor-alpha (TNF-alpha)
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1312/studies/133373
January 01, 2008 - Outcome: Flow-mediated dilation (FMD)
Population: All Participants
Time Point
Measure … Outcome: Total cholesterol
Population: All Participants
Time Point
Measure … Successfully
Outcome: HDL
Population: All Participants
Time Point
Measure … Outcome: Triglycerides
Population: All Participants
Time Point
Measure … Outcome: Fasting blood glucose
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1565/studies/189000
January 01, 2020 - Comments ( 0 ) |
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Was AHI or other measure … Comments ( 0 ) |
Post/View
Baseline sleep measures … Outcome: AE: Treatment harms
Population: All Participants
Time Point
Measure … CPAP
MAD
Comparison Measure
CPAP vs. …
Population: All Participants
Time Point
Measure
CPAP
MAD
-
srdr.ahrq.gov/projects/1520/studies/186799
January 01, 2019 - Antibiotics: Cephalosporin + Metronidazole
Antibiotics: Cephalosporin + Metronidazole
Comparison Measure … Antibiotics: Cephalosporin + Metronidazole
Antibiotics: Cephalosporin + Metronidazole
Comparison Measure … failure
Population: All Participants
Between-Arm Comparisons
Time Point
Measure … Antibiotics: Cephalosporin + Metronidazole
Antibiotics: Cephalosporin + Metronidazole
Comparison Measure … Yes
Comments ( 0 ) |
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Q25: NHLBI - Were the outcome measures prespecified, clearly
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srdr.ahrq.gov/projects/1312/studies/133211
January 01, 2014 - : Insulin resistance or HOMA-IR
Population: All Participants
Time Point
Measure … Outcome: Diastolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Systolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Total cholesterol
Population: All Participants
Time Point
Measure … Outcome: Triglycerides
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1520/studies/186840
January 01, 2011 - Successfully
Outcome: Colorectal cancer
Population: All Participants
Time Point
Measure … Successfully
Outcome: Adenoma >=10 mm
Population: All Participants
Time Point
Measure … Outcome: Adenoma, high grade dysplasia
Population: All Participants
Time Point
Measure … Successfully
Outcome: AE: Perforation
Population: All Participants
Time Point
Measure … Yes
Comments ( 0 ) |
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Q25: NHLBI - Were the outcome measures prespecified, clearly
-
srdr.ahrq.gov/projects/1565/studies/189005
January 01, 2011 - Comments ( 0 ) |
Post/View
Was AHI or other measure … Baseline sleep measures
41.08
37.29 … CPAP
APAP
APAP plus A-Flex
Comparison Measure
APAP plus A-Flex vs. … CPAP
APAP
APAP plus A-Flex
Comparison Measure
APAP plus A-Flex vs. … CPAP
APAP
APAP plus A-Flex
Comparison Measure
APAP plus A-Flex vs.
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srdr.ahrq.gov/projects/1520/studies/186727
December 01, 2013 - 30 day mortality (post-surgical, CD V)
Population: All Participants
Time Point
Measure … - Unplanned (re)hospitalization (CD IV)
Population: All Participants
Time Point
Measure … Outcome: AE - Major cardiac event (CD IV)
Population: All Participants
Time Point
Measure … Outcome: AE - Major cardiac event (CD IV)
Population: All Participants
Time Point
Measure … Yes
Comments ( 0 ) |
Post/View
Q25: NHLBI - Were the outcome measures prespecified, clearly
-
srdr.ahrq.gov/projects/1565/studies/188510
January 01, 2019 - Comments ( 0 ) |
Post/View
Was AHI or other measure … Comments ( 0 ) |
Post/View
Baseline sleep measures …
Population: All Participants
Between-Arm Comparisons
Time Point
Measure … CPAP
No CPAP
Comparison Measure
CPAP vs. … CPAP
No CPAP
Comparison Measure
CPAP vs.
-
srdr.ahrq.gov/projects/1312/studies/133135
January 01, 1996 - Oxidized low density lipoprotein
Population: All Participants
Time Point
Measure … Outcome: Total cholesterol
Population: All Participants
Time Point
Measure … Outcome: Triglycerides
Population: All Participants
Time Point
Measure … Oxidized low density lipoprotein
Population: All Participants
Time Point
Measure … Oxidized low density lipoprotein
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1312/studies/133195
January 01, 2013 - Successfully
Outcome: HDL
Population: All Participants
Time Point
Measure … Outcome: Total cholesterol
Population: All Participants
Time Point
Measure … Outcome: Triglycerides
Population: All Participants
Time Point
Measure … Outcome: Systolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Diastolic blood pressure
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1312/studies/133221
January 01, 2014 - analysis or pulse wave velocity
Population: All Participants
Time Point
Measure … Outcome: Systolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Systolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Diastolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Augmentation index
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1312/studies/133246
January 01, 2009 - Outcome: Systolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Diastolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Total cholesterol
Population: All Participants
Time Point
Measure … Outcome: Fasting blood glucose
Population: All Participants
Time Point
Measure … Outcome: Triglycerides
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1312/studies/133164
January 01, 2013 - Outcome: hsCRP or hs-CRP
Population: All Participants
Time Point
Measure … Outcome: Systolic blood pressure
Population: All Participants
Time Point
Measure … Outcome: Diastolic blood pressure
Population: All Participants
Time Point
Measure … Successfully
Outcome: LDL
Population: All Participants
Time Point
Measure … Outcome: Triglycerides
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1565/studies/189310
January 01, 2017 - Key Questions Addressed
2
KQ 2: What is the evidence that apnea and hypopnea-based measures … and apnea-hypopnea indices) used in current practice and research are valid surrogate or intermediate measures … Follow Up
Answer
Follow-up Answer
Measure(s) being evaluated) … Outcome: HTN: incident HTN
Population: All Participants
Time Point
Measure … Successfully
Outcome: AHI
Population: All Participants
Time Point
Measure
-
srdr.ahrq.gov/projects/1520/studies/197514
January 01, 2020 - Successfully
Outcome: Colorectal cancer
Population: All Participants
Time Point
Measure … Successfully
Outcome: Procedural complication
Population: All Participants
Time Point
Measure … Successfully
Outcome: Failed/incomplete procedure
Population: All Participants
Time Point
Measure … possible complicated diverticulitis
Comments ( 0 ) |
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Q25: NHLBI - Were the outcome measures
-
srdr.ahrq.gov/projects/1520/studies/193256
January 01, 2019 - Successfully
Outcome: Colorectal cancer
Population: All Participants
Time Point
Measure … Outcome: Colorectal cancer
Population: Uncomplicated diverticulitis
Time Point
Measure … Successfully
Outcome: Colorectal cancer
Population: Complicated diverticulitis
Time Point
Measure … Yes
Comments ( 0 ) |
Post/View
Q25: NHLBI - Were the outcome measures prespecified, clearly