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461. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
     September 01, 2012 - It detects low concentrations of FLCs and can measure the ratio of kappa chains to lambda chains. … Outcomes Measures of diagnostic accuracy (e.g., sensitivity, specificity, or predictive value) in … It measures kappa and lambda light chains separately and detects low concentrations of FLCs—less than … Outcomes Measures of diagnostic accuracy (e.g., sensitivity, specificity, or predictive value) in … Measures of diagnostic accuracy (e.g., sensitivity, specificity, or predictive value) in different

462. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
     June 23, 2011 - Some bundled payment programs include an element of pay-for-performance related to quality measures.2 … o Quality of care, considered in the following categories used by the National Quality Measures Clearinghouse7 … Studies may report on this as a measure of a potential adverse effect of bundled payment on risk selection … National Quality Measures Clearinghouse (NQMC). 2010. … For a comparison of two treatments, directness implies that head- to-head trials measure the most important

463. Topic 0549 Diagnosis and Management of Gout NSD _SJ Clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
     June 24, 2014 - of treatment differ according to patient baseline uric acid levels and blood and urine biochemical measures … gout being treated to prevent gout recurrence, do results of follow-up blood and urine biochemistry measures

464. Pharmacologic Management of Acute Pain by EMS in the Prehospital Setting Protocol Amendment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
     January 28, 2019 - adequately treated if it is not appropriately assessed, a careful evaluation of validated tools to measure … Current guidelines7 for the management of prehospital trauma pain recommend specific pain scales, broken … absence of a gold standard assessment tool.8 Of particular interest is the evidence for use of these scales … , and the results of each outcome, including measures of variability. … The arcsine difference as a measure of treatment effect in meta-analysis with zero cells.

465. S3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s3.pdf
     October 01, 2007 - Reduction in burden of illness: a new efficacy measure for prevention trials.

466. Autism-Update Clinician (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_clinician.pdf
     September 01, 2014 - methodological rigor in the field, including: Ă Consistent use of standardized, validated outcome measure

467. PowerPoint Presentation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/krishnan_ahrq-mcda-presentation.pdf
     August 27, 2012 - I 7 (6 - 8) • Several topics identified • Preferences variable • Simple ranks do not measure

468. Disposition of Comments Report for The Clinical Utility of Fractional Exhaled Nitric Oxide (FeNO) in Asthma Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-197-fractional-exhaled-nitric-oxide-disposition-comments.pdf
     December 20, 2017 - using FENO is supported by data and potentially by cost: using FENO in addition to asthma control measures … research section about how studies evaluating disease activity and outcome, should use validated measures … i.e., clinical diagnosis, spirometry, bronchial challenge, bronchodilator response, etc) directly measure … Technology to measure FeNO in children < 6yrs is currently not clinically available in the United States … The report also includes very little strong evidence regarding FeNO for any measures other than decreased

469. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
     January 01, 2012 - with ASDs  Key facts: The Q Sensor (Affectiva, Inc., Waltham, MA) is a wireless device intended to measure … A noninvasive brain-imaging technique that indirectly measures neural activity by detecting local … Sensor™ (Affectiva, Inc., Waltham, MA) is a wireless device worn on the wrist and is intended to measure … The device is placed around the wrist and secured with a Velcro strap. 2 To measure and record data … No differences were detected between HBOT and placebo groups across any of the outcome measures.

470. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
     December 15, 2010 - Indirect evidence includes pharmacokinetic and/or mechanistic studies whereby surrogate measures of … www.effectivehealthcare.ahrq.gov Published Online: April 28, 2011 Page 14 of 26 populations and may not measure … For observational studies, we will extract crude rates or relative measures of the association (relative … medications/supplements, and health status, including comorbidities and LDL-C and blood pressure if these measures … For studies with zero events in one arm, estimation of effect measures will require the addition of

471. A Bayesian Missing Data Framework for Multiple Continuous Outcome Mixed Treatment Comparisons (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research-2013.pdf
     January 01, 2013 - outcomes equivalently, and all of their scales cover the same qualitative ranges (from “no pain” to … Among the 54 studies, 51 measure the pain outcome, 26 measure the disability outcome, and 23 include … of goodness of fit, and we im , a measure of complexity. … Bayesian measures of model complexity and fit. … Effect of preoperative exercise on measures of functional status in men and women undergoing total

472. Disposition of Comments for CER 195 Management of Uterine Fibroids (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-195-disposition-comments-uterine-fibroids.pdf
     December 14, 2017 - As above, change is a type of outcome measure. … Reviewer (Allergen) Methods Quality of Life (pg. 11) – AHRQ’s Current Symptom Severity Scale Does Not Measure … In fact, the intent of the Symptom Severity Scale is not to measure the “variability and severity of … It measures the “distress due to the frequency and severity of uterine leimyomata symptoms”. … Instead, item response choices are presented as five-level Likert scales ranging from ‘not at all’

473. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0313_02-09-2009.pdf
     January 01, 2009 - What specific dietary measures reduce stone formation? 3. … A number of drugs and dietary measures have been shown to reduce the rate of stone recurrence.

474. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-knee-update-disposition-archived.pdf
     May 04, 2017 - Reviewer #4 Methods Page 11 line 15: "...we did not pool studies that used different tools to measure … Definitions and diagnostic criteria for outcome measures are appropriate. … The summary of results can be dense to read due to the multiple scales— low/moderate/high strength … the TENS over months duration or are we talking about short term application ( a few weeks, then measure … Peer Reviewer #2 Discussion /Conclusio n Also, another outcome measure may be exercise or activity

475. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-disposition.pdf
     May 04, 2017 - Reviewer #4 Methods Page 11 line 15: "...we did not pool studies that used different tools to measure … Definitions and diagnostic criteria for outcome measures are appropriate. … The summary of results can be dense to read due to the multiple scales— low/moderate/high strength … the TENS over months duration or are we talking about short term application ( a few weeks, then measure … Peer Reviewer #2 Discussion /Conclusio n Also, another outcome measure may be exercise or activity

476. Mrsa-Screening-2010 Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
     January 01, 2010 - Despite the adoption of infection-control measures, the incidence of MRSA infection at most U.S. … Given the continued dissemination of MRSA at most U.S. hospitals, it is clear that these measures, as … impact of a screening program without detailed information about the deployment of decolonization measures … The guidelines further advise that these measures “should be implemented in all types of health care … To attempt to measure the favorable impact of screening for MRSA carriage while ignoring its potential

477. S38 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s38.pdf
     October 01, 2007 - Thus, measures of agreement in treatments received by patients of different providers within a practice … One simple measure of sharing would be the percent of potentially eligible patients who see multiple … More sophisti- cated measures of clustering within practices could use mul- tilevel models to quantify … intervention or control group in blocks of 4 within the 12 strata formed by the cross-classification of these measures

478. Lung-Cancer-Nonsurgical-Therapies Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
     June 01, 2013 - secondary to an inoperable obstructive endoluminal NSCLC Treatment and Evidence Base Outcome Unit of Measure … • LCT is of interest to patients because it measures the effectiveness of an intervention in disease … Although OS is the primary direct outcome for any cancer intervention study, it may not be the best measure … These measures include generic measures such as SF-36 and EQ-5D and lung cancer–specific measures such … Questionnaire (EORTC QLQ) modules C30 and LC13 and Functional Assessment of Cancer Therapy-Lung (FACT-L) to measure

479. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - and CATD, then many of the studies reviewed are irrelevant, because they don’t look some general measure … I found it helpful that you reported scoring ranges for scales (e.g., Tabl 4!. … , depressive symptoms, and driving measures should be included. … Post-intervention outcomes appear to be measure after the 3 month intervention (our review required … Post-intervention outcomes appear to be measure after the 3 month intervention (our review required

480. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - and CATD, then many of the studies reviewed are irrelevant, because they don’t look some general measure … I found it helpful that you reported scoring ranges for scales (e.g., Tabl 4!. … , depressive symptoms, and driving measures should be included. … Post-intervention outcomes appear to be measure after the 3 month intervention (our review required … Post-intervention outcomes appear to be measure after the 3 month intervention (our review required