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261. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_executive.pdf
     March 01, 2017 - Improvement or slower deterioration from baseline biomarker measures could indicate a slowing of age … KQ 3: What is the strength of association between outcome measures examined in KQs 1 or 2 including … neuropsychological tests for extraction and analysis by their purpose and/or what they attempt to measure … Many studies originally designed for other purposes have added cognitive measures post- hoc. … Although no one measure is adequate for all applications, movement towards the use of batteries with

262. Disposition of Comments for Strategies To Prevent Weight Gain Among Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_disposition-comments.pdf
     March 25, 2013 - Environment level interventions can benefit people of all weights. … In a study of weight – where weights are objectively measured on scales (most of which are digital) … Thus, the public health goal should not be keeping adult weights between 18.5 and 29.9 (as stated by … We consider multiple measures of weight for this reason. … BMI is a standard measure to categorize weight.

263. Disposition of Comments for Use of Natriuretic Peptide Measurement in the Management of Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
     November 20, 2013 - tackle adequately the complexity of diagnosis of heart failure and in particular the superiority of measure … Rev 7 Intro The definitions for the outcome measures are appropriate. … statement: we see over and over again that clinicians do have problem in interpreting diagnostic accuracy measures … If a translation from accuracy measures to patient important outcomes is desired, then there is almost … If I know the age and sex of a person, do I really need to measure BNP on top of that?

264. final Fibromyalgia CER protocol_3-31-14 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
     April 03, 2014 - the ACR that eliminated the tender point examination, but relied on physician-rated severity in two scales … Clinical applications of visual analogue scales: a critical review. … Psychometric properties of the Medical Outcomes Study Sleep measure. … Yes Valid measures, groups ~equivalent No Non-validated measures or non- equivalent groups … Yes Measures were valid and reliable (i.e. objective measure, validated scale/tool); consistent

265. Dementia-Agitation-Aggression Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
     November 13, 2014 - For example, the Neuropsychiatric Inventory (NPI), one of the most commonly used research tools to measure … evaluating behavioral symptoms can be grouped into two broad categories: general and specific.18 General measures … Most studies that report results from general measures report overall summary scores. … We will assess strength of evidence for key final health outcomes measured with validated scales. … Assessing neuropsychiatric symptoms in people with dementia: a systematic review of measures.

266. Disposition of Comments for CER 182 Glasgow Coma Scale (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow-disposition-170415.pdf
     January 12, 2017 - AUROC by definition is based on sensitivity and specificity calculated at different values of the measure … TEP Reviewer #2 Methods Are the definitions or diagnostic criteria for the outcome measures appropriate … threshold for the measure is (e.g. a kappa with LCL >0.4 indicates moderate agreement between assessors … Peer Reviewer #4 Methods Are the definitions or diagnostic criteria for the outcome measures appropriate … tGCS is associated with slightly better predictive utility than the mGCS, based on the AUROC, a measure

267. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
     July 01, 2023 - What measures or indicators have been used to examine the harms associated with the target of the patient … & Medicaid Services (CMS) patient safety measures, AHRQ’s Patient Safety Indicators, or the National … Committee for Quality Assurance (NCQA) patient safety related measures. … Utilization of health care services (focusing on the main utilization measure reported in the … study) Implementation • Barriers and facilitators • Resources (cost, staff, time) • Measures

268. PATIENTSLIKEME (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/clifford.pdf
     May 29, 2025 - So that's one of the reasons that the patient community that we built does things like measure data … which correlates with the RAND of 36, for any of you who care about these sorts of things -- which measures … We measure adherence burden, cost, side effects. … You can purposely -- purposively create these things to serve as a patient reported outcomes measures

269. Evidence-Summary-Cer-197-Fractional-Exhaled-Nitric-Oxide (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-197-fractional-exhaled-nitric-oxide.pdf
     December 01, 2017 - likely insufficient and its ability to predict exacerbations can be substantially enhanced by clinical measures … quite heterogeneous in terms of design, population, control tests, control strategies, and outcome measures … Studies evaluating disease activity and outcomes should use validated measures of activity and well defined

270. Disposition of Comments for Comparative Effectiveness Review 133 Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
     May 27, 2014 - visits) are important because an increase in these outcomes may be an unintended consequence of measures … CMS measures 30-day readmission because there is evidence that suggests a higher proportion of early … The definitions or diagnostic criteria are appropriate for the outcome measures. … The outcome measures chosen are the relevant ones for this population. … Due to heterogeneity in scales and reporting of the measures in general, it was difficult to assess

271. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
     September 08, 2011 - Health outcomes: morbidity, mortality, function, and quality of life as measured by validated scales … therapy Health outcomes: morbidity, mortality function, and quality of life as measured by validated scales … Sample variability measures Precision of estimate p values  Regression modeling techniques … Source: www.effectivehealthcare.ahrq.gov Published Online: September 8, 2011 o Were outcome measures … o Well-described study population o Well-described intervention o Use of validated outcome measures

272. EPC Systematic Review Protocol: Achieving Health Equity in Preventive Services: Systematic Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-equity-protocol.pdf
     January 01, 2020 - progression, and premature or excessive mortality from specific conditions; (2) a population health measure … https://www.healthypeople.gov/2020/about/foundation-health- measures/Disparities#5. … europe/ or exp islands/ or exp oceania/ 25 exp Obesity/ 26 Overweight/ 27 exp "Body Weights … and Measures"/ 28 (obese or obesity or overweight or "body mass" or bmi or weight).ti,ab,kw. … "MAYAS -- Ethnic identity" OR DE "MEXICANS -- Ethnic identity" OR DE "MULTIGROUP Ethnic Identity Measure

273. Antipsychotics-Adults Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
     August 01, 2012 - the Clinical Global Impression–Improvement (CGI–I) and Clinical Global Impression–Severity (CGI–S) scales … No differences were observed for the other five scales of general symptoms assessed. … Few studies compared the same antipsychotic medications and dosage using similar measures; various scales … Consensus is needed regarding outcomes and measures used to assess outcomes. … Numerous studies provided data on core illness symptoms; however, many different scales were used to

274. Disposition of Comments Report for CER 207 on PTSD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-207-ptsd-disposition-comments.pdf
     May 17, 2018 - We did not include Cronbach’s alpha as a measure of reliability. … Dichotomizing that measure will always decrease the effect size and attenuate power. … Thus I am concerned about what seems equal emphasis on measures of symptom reduction (ordinal) and loss … We did not attempt to give “equal” meaning to the two measures of symptom reduction and loss of diagnosis … few actually reported symptom reduction or loss of diagnosis in addition to other continuous-type measures

275. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-postpartum-screening_research-protocol.pdf
     May 01, 2013 - instruments of infant health and development, including, but not necessarily limited to, the Bayley Scales … This allows an approach that compares total tests or false-positive results as a measure of “cost” or … “harm” to a measure of benefit, such as “cases of depression detected.” … Inventory-IA BDI-II Beck Depression Inventory-II BPDS Bromley Postnatal Depression Scale BSID Bayley Scales … questionnaires[mesh] OR Interviews as Topic[Mesh] OR Psychometrics[Mesh] OR Psychiatric Status Rating Scales

276. Politi (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/politi.pdf
     May 29, 2025 - • How do we measure or quantify effective  management of uncertainty?

277. Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Nosocomial Pneumonia | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/pneumonia-antibiotic-treatment/research-protocol

278. Ch 3-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
     September 21, 2012 - Yet, studies tend to emphasize a single measure of the impact of treatment, the ATE, which is a summary … outcomes (either a clinical event such as myocardial infarction or a change in a continuous clinical measure … , these characteristics may represent proxies for genetic differences that are more difficult to measure … Estimation and Reporting of Heterogeneity of Treatment Effects outcome measures, thereby improving statistical … Measures of exposure, outcome, and covariates should address misclassification and seek to limit potential

279. Methods Guide for Medical Test Reviews Chapter 12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
     July 01, 2012 - Some of these measures, singly or in combination as a prediction model, can be clinically useful. … Measures to assess the prognostic ability of the stratified Cox proportional hazards model. … Overall C as a measure of discrimination in survival analysis: model specific population value and … Extensions of net reclassifcation improvement calculations to measure usefulness of new biomarkers. … A new measure of prognostic separation in survival data.

280. PKU Surveillance Assessment_CER 56_Low (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_surveillance.pdf
     January 15, 2013 - Nineteen unique studies determined to be too heterogeneous with respect to the neuropsychological measures … quality from poor to good, with varying doses, adherence rates, baseline Phe levels, and outcome measures … ), only 1 reported outcomes of interest, including measures of cognition and nutritional status (most … One expert mentioned a BioMarin PKU-016 study that measures outcomes of tetrahydrobiopterin in relation … Do Not Know with varying doses, adherence rates, baseline Phe levels, and outcome measures), only