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2481. EPC Methods: An Exploration of Methods and Context for the Production of Rapid Reviews (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rapid-review-production_white-paper.pdf
      February 01, 2015 - systematic review, albeit one with a tightly constrained scope and that often sacrifices quality control measures

2482. Pneumonia-Antibiotic-Treatment Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
      November 01, 2014 - 1 Comparative Effectiveness Review Number 136 Pharmacokinetic/Pharmacodynamic Measures for Guiding … Of concern are both presumed benefits and harms of using PK/PD measures for these purposes. … For people with hospital-acquired pneumonia, how does using PK/PD measures to inform decisions about … For KQs 1 and 3, eligible comparators included: no use of PK/PD measures, different targets of PK/PD … Disposition of articles about using PK/PD measures in hospital-acquired pneumonia Key Question 1.

2483. Peripheral-Artery-Disease-Treatment Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
      May 01, 2013 - Continuous outcome measures comparing two treatments made on different scales (such as quality-of-life … RCTs reporting continuous outcome measures on different scales (such as functional capacity and quality-of-life … interval. 18 • A random-effects meta-analysis of 10 studies examining the difference in the SF-36 measure … thought to be less responsive to change than a disease- specific measure is. … However, we would expect that RCTs or 37 prospective cohort studies would make it a priority to measure

2484. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
      September 25, 2013 - Definitions, outcome measures and statistical methods are appropriate. … The outcome measures used for this topic are quite complicated with several of them relying on epidemiological … Analytic sensitivity and specificity are used in the characterization of tests that measure levels of … identifies 40 studies that examined the association of genotype results with platelet reactivity measures … Teirstein Results Platelet reactivity should be considered a viable surrogate outcome measure.

2485. Evidence-based Practice Center Future Research Needs (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ongoing-studies-evidence_research.pdf
      December 01, 2010 - Evidence-based Practice Center Future Research Needs Methods Future Research Needs Report Number 1 Finding Evidence on Ongoing Studies This report is based on research conducted by the Minnesota Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and …

2486. mmeta: Exact Bayesian Inference for Multivariate Meta-analysis of Binary Outcomes | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/mmeta/abstract
      April 01, 2018 - The exact posterior distributions of the study-specific comparative measures (e.g., odds ratio, relative … cross-platform, open-source program for performing meta-analysis for combining evidence on comparative measures … Specifically, the R package performs maximum likelihood inference on the overall comparative measures … , and provides exact Bayesian inference on the posterior distribution of study-specific comparative measures

2487. CERs Report cover (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-feature-treatment-future_research.pdf
      September 23, 2010 - 2 How important is it to have a tool box of validated outcomes measures? … Consistent use of validated outcome measures. … research would benefit from design and measurement improvements, and that the optimal outcomes to measure … Consistent use of validated quality of life and outcome assessment tools -crosswalk studies for each measure … Toolbox of approved, validated measures 3.

2488. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/health-literacy_research-protocol.pdf
      January 22, 2010 - The assessment included items intended to directly measure health literacy. …  Measures of disease incidence, prevalence, morbidity, and mortality. … Low parental literacy is associated with worse asthma care measures in children. … Testing the feasibility of an interactive learning styles measure for U.S. … Agreement between scales in the measurement of breast cancer risk perceptions.

2489. FRN 35 - Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
      April 01, 2013 - Second, outcomes used to measure effectiveness are also subjective and self-reported. … Specifically, few studies assessed the clinical importance of the changes in quality of life or disability scales … from several trials that analyzed quality of life types of outcomes (as measured with a variety of scales … Specifically, few studies assessed the clinical importance of the changes in quality of life or disability scales … from several trials that analyzed quality of life types of outcomes (as measured with a variety of scales

2490. Research Protocol: Improving Cultural Competence To Reduce Health Disparities for Priority Populations (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cultural-competence_research-protocol.pdf
      July 09, 2014 - outcomes of interest are reductions in disparities between populations for a given health outcome measure … Outcomes measurement issues inherent in the psychometric properties of the questionnaires used to measure … We will assess statistical heterogeneity with Cochran’s Q test and measure magnitude with I2 statistic … Yes Measure valid and reliable (i.e. objective measures, well validated scale, provider report … (self-report, scales with lower validity, reliability); not equivalent across groups Uncertain Could

2491. PATIENTSLIKEME (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/clifford.pdf
      January 06, 2017 - So that's one of the reasons that the patient community that we built does things like measure data … which correlates with the RAND of 36, for any of you who care about these sorts of things -- which measures … We measure adherence burden, cost, side effects. … You can purposely -- purposively create these things to serve as a patient reported outcomes measures

2492. Effective Health Care (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0316_03-12-2009.pdf
      January 01, 2009 - Effective Health Care Topic Number(s): 0128 Document Completion Date: 6-12-09 1 Results of Topic Selection Process & Next Steps  Self-measured blood pressure monitoring will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, comparato…

2493. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/chronic-cough_research-protocol.pdf
      October 22, 2012 - KQ 2: All of the above-listed interventions compared both within class and across classes Outcome measures … and responsiveness index  Feasibility: response rate, time required  Validity: test validity measures … sputum (relevant only to patients with wet or productive cough) or bronchoprovocation challenge (measures … in comparison with care models currently in use, and clinical relevance and timing of the outcome measures … ] OR “visual analogue”[tiab]OR severity[tiab] OR sound[tiab] OR sounds[tiab] OR register*[tiab] OR measure

2494. Disposition of Comments Report for Prevention of Healthcare-Associated Infections (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_disposition-comments.pdf
      November 30, 2012 - of the key issues with the VAP bundle adherence literature (and likely most literature on process measure … defs -- also good, although I have some mild concern regarding analysis of some process measure adherence … Outcome and process measures (definitions) also very well defined. … The focus is on change in adherence not the prevention measure. … Focus is on change in provider behavior, not the prevention measure specifically.

2495. Disparities-Quality-Improvement Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_executive.pdf
      August 01, 2012 - To measure potential changes in disparity between patient groups, studies had to include a target and … Paper Selection Process We included studies that captured health outcome measures and/or process measures … outcomes such as blood pressure and HbA1c); process measures (e.g., proportion of patients treated … Inclusion of a target group and an internal or external referent group to measure changes in disparities … In addition, they were required to provide data that could be used to measure a disparity before and

2496. - (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
      January 01, 2009 - Body Mass Index (BMI): Measure of body fat relative to height. … Bone Mineral Content (BMC): Measure of the amount of bone in the body. … I 2 : Measure of degree of variation due to statistical heterogeneity. … Standard Deviations (SDs): A measure of the variability of a data set. … Sweat Test: A standard diagnostic test for cystic fibrosis that measures the concentration of chloride

2497. Mass-Casualty-Events-Scarce-Resources Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
      June 01, 2012 - Triage systems and explicit triage acuity scales have been used in emergency departments for many years … Several studies did not measure health outcomes or even the most relevant process outcomes. … Instead, most of the studies focused on measures of throughput. … further broaden our coverage of the topic, we included in a separate section studies that had some measure … There was some degree of subjectivity in assigning scores to each item in our quality assessment scales

2498. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
      June 01, 2010 - In this setting, once all routine measures are utilized (e.g., clamps, plasma transfusions, tourniquets … as an end-stage measure. … Does the hospitalization weights apply to non-hospitalized encounters? … The weights were used to adjust for the increasing number of hospitals included in the Premier sample … The data are representative without statistical manipulation beyond use of the statistical weights

2499. Disposition of Comments for CER 147 Menopausal Symptoms: Comparative Effectiveness of Therapies (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
      March 05, 2015 - When describing the many scales used to measure outcomes, authors should consistently note direction … Direction of all scales for all outcomes have been defined. … Scales for outcome measures appear to be focused on overall QOL measures and components of QOL measures … The table has been edited so that all reflect some measure of improvement. … VAS scales have been removed.

2500. Disposition of Comments for CER 202 Effectiveness and Safety of Bronchial Thermoplasty in the Management of Asthma (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
      December 14, 2017 - healthcare utilization was not directly measured within the AIR or RISA trials, these trials did measure … FEV1 data was collected in AIR2 as a safety measure, to confirm that pulmonary physiology does not … 2010 AIR2 trial, there existed a 96% PPS of an improvement in the asthma-specific quality of life measure … may not be clinically important, as it did not achieve the minimum important difference for this measure … Reviewer 10 Ann Roy on behalf of Boston Scientific Results Detailed Synthesis – Symptoms (secondary measure