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241. Comparative Effectiveness Review No. 234 Evidence Summary: Management of Primary Headaches in Pregnancy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
     November 01, 2020 - but calcium channel blockers (any, but nifedipine in particular) and antihistamines (any) may have a low … SoE), and oral magnesium (low SoE). … (low SoE). … No serious maternal adverse effects occurred (low SoE). … (low to moderate SoE), and intravenous magnesium (low SoE).

242. Comparative Effectiveness Review No. 234 Evidence Summary: Management of Primary Headaches in Pregnancy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
     November 01, 2020 - but calcium channel blockers (any, but nifedipine in particular) and antihistamines (any) may have a low … SoE), and oral magnesium (low SoE). … (low SoE). … No serious maternal adverse effects occurred (low SoE). … (low to moderate SoE), and intravenous magnesium (low SoE).

243. Management of Insomnia Disorder in Adults: Current State of the Evidence | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/insomnia/clinician
     March 01, 2021 - ] ) May improve other outcomes ( [evidence low] ) May improve ( [evidence low] ) May … ] ) May improve ( [evidence low] ) May improve some outcomes ( [evidence low] ) … ER May improve ( [evidence low] ) May improve some outcomes ( [evidence low] ) ( [evidence … insufficient] ) May improve some outcomes ( [evidence low] ) May improve ( [evidence low … Low: [evidence low] Low confidence that the evidence reflects the true effect.

244. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/47877/psn-pdf
     June 15, 2019 - End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography … End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography … https://psnet.ahrq.gov/issue/end-end-lung-cancer-screening-three-dimensional-deep-learning-low-dose- … https://psnet.ahrq.gov/issue/end-end-lung-cancer-screening-three-dimensional-deep-learning-low-dose-chest-computed … https://psnet.ahrq.gov/issue/end-end-lung-cancer-screening-three-dimensional-deep-learning-low-dose-chest-computed

245. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/837631/psn-pdf
     July 06, 2022 - The impact of an electronic alert to reduce the risk of co- prescription of low molecular weight heparins … The impact of an electronic alert to reduce the risk of co-prescription of low molecular weight heparins … https://psnet.ahrq.gov/issue/impact-electronic-alert-reduce-risk-co-prescription-low-molecular-weight … Researchers assessed prescribers’ actions following an alert for new prescriptions of Low Molecular … https://psnet.ahrq.gov/issue/impact-electronic-alert-reduce-risk-co-prescription-low-molecular-weight-heparins-and-direct

246. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/72804/psn-pdf
     March 03, 2021 - How to do no harm: empowering local leaders to make care safer in low-resource settings. … How to do no harm: empowering local leaders to make care safer in low-resource settings. … https://psnet.ahrq.gov/issue/how-do-no-harm-empowering-local-leaders-make-care-safer-low-resource- settings … https://psnet.ahrq.gov/issue/how-do-no-harm-empowering-local-leaders-make-care-safer-low-resource-settings … https://psnet.ahrq.gov/issue/how-do-no-harm-empowering-local-leaders-make-care-safer-low-resource-settings

247. Spotlight Case [MONTH] 2003 (ppt file)
     psnet.ahrq.gov/sites/default/files/import/webmm.ahrq.gov.170_slideshow.ppt
     March 01, 2008 - What diagnostic tests are useful for low back pain? … Pain Regional mechanical low back pain (≥ 90%) Mechanical low back pain with neurogenic leg pain (7%- … Regional mechanical low back pain Non-specific mechanical low back pain (sprain, strain, lumbago, etc … A clinician's approach to acute low back pain. … Low back pain.

248. Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/Hfz3GBNZhq5j4SXUt8R2d5
     September 28, 2021 - low-dose aspirin. … Low-dose aspirin to prevent preeclampsia in women at high risk. … CLASP (Collaborative Low-dose Aspirin Study in Pregnancy) Collaborative Group. … Low dose aspirin in pregnancy and early childhood development: follow up of the collaborative low dose … ACOG Committee Opinion No. 743: low-dose aspirin use during pregnancy.

249. Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/Cjgb95YGBUaHjfn3MNR9xz
     September 28, 2021 - low-dose aspirin. … Low-dose aspirin to prevent preeclampsia in women at high risk. … CLASP (Collaborative Low-dose Aspirin Study in Pregnancy) Collaborative Group. … Low dose aspirin in pregnancy and early childhood development: follow up of the collaborative low dose … ACOG Committee Opinion No. 743: low-dose aspirin use during pregnancy.

250. JAMA (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/ymZSPeLcwZ9rxTC-7zdWbp
     July 11, 2022 - low-dose aspirin. … Low-dose aspirin to prevent preeclampsia in women at high risk. … CLASP (Collaborative Low-dose Aspirin Study in Pregnancy) Collaborative Group. … Low dose aspirin in pregnancy and early childhood development: follow up of the collaborative low dose … ACOG Committee Opinion No. 743: low-dose aspirin use during pregnancy.

251. Final Recommendation Statement: Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
     September 28, 2021 - Pregnant persons with 1 or more high-risk factors should receive low-dose aspirin. … Low-dose aspirin to prevent preeclampsia in women at high risk. … CLASP (Collaborative Low-dose Aspirin Study in Pregnancy) Collaborative Group. … Low dose aspirin in pregnancy and early childhood development: follow up of the Collaborative Low dose … ACOG Committee Opinion No. 743: low-dose aspirin use during pregnancy.

252. Evidence Summary: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/system/files/cer-233-diverticulitis-evidence-summary.pdf
     October 01, 2020 - moderate strength of evidence [SoE]) and may increase appropriate management versus clinical diagnosis (low … Misdiagnoses on CT may not increase the risk of poor clinical outcomes (low SoE). … The significance of incidental findings is unclear (low SoE). … uncomplicated acute diverticulitis, outpatient management may be as effective as inpatient care (low … Colonoscopy: There is low SoE that patients with recent acute diverticulitis may be at about 3 times

253. Evidence Summary: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
     October 01, 2020 - moderate strength of evidence [SoE]) and may increase appropriate management versus clinical diagnosis (low … Misdiagnoses on CT may not increase the risk of poor clinical outcomes (low SoE). … The significance of incidental findings is unclear (low SoE). … uncomplicated acute diverticulitis, outpatient management may be as effective as inpatient care (low … Colonoscopy: There is low SoE that patients with recent acute diverticulitis may be at about 3 times

254. Evidence Summary: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
     October 01, 2020 - moderate strength of evidence [SoE]) and may increase appropriate management versus clinical diagnosis (low … Misdiagnoses on CT may not increase the risk of poor clinical outcomes (low SoE). … The significance of incidental findings is unclear (low SoE). … uncomplicated acute diverticulitis, outpatient management may be as effective as inpatient care (low … Colonoscopy: There is low SoE that patients with recent acute diverticulitis may be at about 3 times

255. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/ptsd-3-draft-report.pdf
     January 12, 2022 - High High Low High Angelakis 2020 Low Low Low Low Low Low Baekkelund 2021 Low Low Low Low Low Low … Bellehsen 2021 Low Low Low Low Low Low Bisson 2020 Low Low Low Low Low Low Bohus 2020 Low Low Some … Low Low Low Boterhoven de Haan 2020 Low Low Low Low Low Low Dadabayev 2020 Low Low Low Low Low Low … Davis 2020 Low Low Low Low Low Low Dunlop 2021 Low Low Low Low Low Low Duran 2020 Low Low High Some … 2021 Low Low Low High Low High Spangler 2020 Low Low Low Low Low Low Tang 2021 Low Low High Low Low

256. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/thromboembolism-update/research-2017
     January 01, 2021 - Most studies evaluated low molecular weight heparin (LMWH), not low-risk interventions (such as aspirin … Higher dose FXaI has lower total VTE risk (low SoE). … For TKR: LMWH has lower DVT risks than VKA (low to high SoE), but VKA has less major bleeding (low SoE … bleeding (low SoE) and more study-defined serious adverse events (low SoE). … Higher dose FXaI has lower risk of various VTE outcomes (low to moderate SoE).

257. Recommendation: Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
     September 28, 2021 - Pregnant persons with 1 or more high-risk factors should receive low-dose aspirin. … Low-dose aspirin to prevent preeclampsia in women at high risk. … CLASP (Collaborative Low-dose Aspirin Study in Pregnancy) Collaborative Group. … Low dose aspirin in pregnancy and early childhood development: follow up of the Collaborative Low dose … ACOG Committee Opinion No. 743: low-dose aspirin use during pregnancy.

258. Topic Suggestion Description | Effective Health Care Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/diagnosis-and-treatment-of-low-back-painbr-key-questionsbr-olliin-patients-with-low-back-pain-what-are-the-benefits-and-harms-of-identifying-risk-factors-for-chronicity-and-targeting-treatment-based-on-assessed-riskliliin-pat
     March 11, 2013 - Diagnosis and treatment of low back pain: Key questions: In patients with low back pain, what are the … back pain, radicular low back pain, or spinal stenosis? … back pain, radicular low back pain, or spinal stenosis? … back pain, radicular low back pain, or spinal stenosis? … of flares of low back pain in patients with chronic low back pain?

259. Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/radiation-therapy-bone-metastases/research
     December 01, 2023 - SOE Harms/AEs — Toxicity, Acute Grade 3, 4 Any time None   low SOE           Delivery techniques for … SOE Skeletal Function (SINS) ≥12 weeks None 1 RCT, N=229 low SOE Quality of Life Post-RT to 26 weeks … , 95% CI 0.18 to 16.75, I 2 =74.6% low SOE Harms/AEs — SCC; Pain Flare Post-RT and 26 weeks None   low … , Not Reported None 1 RCT, N=298 low SOE           EBRT plus bisphosphonate vs. … Low: Low confidence that the evidence reflects the true effect; further research is likely to change

260. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
     February 01, 2012 - SGA (3 RCTs, 1 PCS) Low No significant difference. symptoms Clozapine vs. olanzapine Low No significant … Low No significant difference. (2 RCTs, 1 PCS) Haloperidol vs. risperidone Low No significant difference … Low No significant difference. (1 RCT, 1 PCS, 1 RCS) Clozapine vs. risperidone Low No significant difference … ) Low No significant difference. … Olanzapine vs. risperidone Low No significant difference. (4 RCTs, 1 PCS) SGA vs. placebo (2 RCTs) Low