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srdrplus.ahrq.gov/published_projects?page=30
June 27, 2021 - ), but no improvement in pain was seen at any time (SOE: Low). … Exercise was also associated with moderate improvement in pain (SOE: Low). … The effect on function was sustained intermediate term (SOE: Low). … (SOE: Moderate) or multidisciplinary rehabilitation (SOE: Low) was seen. … evidence), while topiramate and allopurinol showed no benefit (low-strength evidence).
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srdrplus.ahrq.gov/published_projects?page=45
June 23, 2021 - Combining palliative care and primary care home visits increased the likelihood of death at home (low … Low back pain is common and many pharmacological and nonpharmacological therapies are available. … For acute low back pain, evidence suggested that NSAIDs (strength of evidence [SOE]: low to moderate) … , skeletal muscle relaxants (SOE: moderate), opioids (SOE: low), exercise (SOE: low), and superficial … ) and systemic corticosteroids (SOE: low) are no more effective than placebo.
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srdrplus.ahrq.gov/published_projects?page=19
June 27, 2021 - There was low SOE for no difference in these patients for BVM versus SGA and SGA versus ETI. … Low SOE also supported no difference for first-pass success in adult medical patients. … Some opioids may be less effective than some antiemetics or dexamethasone (low SOE). … SOE), acupuncture (low SOE), chamomile oil (low SOE), external trigeminal nerve stimulation (low SOE … ), and eye movement desensitization re-processing (low SOE).
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srdrplus.ahrq.gov/published_projects?page=23
June 27, 2021 - RCTs) of noninvasive nonpharmacological treatments for five common chronic pain conditions (chronic low … laser therapy, and yoga (SOE: low). … Chronic neck pain: In the short-term, low-level laser therapy (SOE: moderate) and massage (SOE: low) … Compared with acetaminophen, Pilates improved both function and pain (SOE: low). … Functional improvement persisted into intermediate term, but pain improvement did not (SOE: low).
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srdrplus.ahrq.gov/published_projects?page=47
June 23, 2021 - and there was variability in the lymph node dissection techniques evaluated (strength of evidence: low … statistically significant effect and there was some inconsistency in findings (strength of evidence: low … READ MORE Published on June 23, 2021 Pain Management Injection Therapies for Low-back Pain [Entered … Low back pain is common and injections with corticosteroids are a frequently used treatment option. … ), and risk of surgery at short-term followup (relative risk [RR] 0.62, 95% CI 0.41 to 0.92) (SOE: low
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srdrplus.ahrq.gov/published_projects?page=26
June 27, 2021 - in the change of pain scores with opioids versus ketamine administered primarily intravenously (IV) (low … SOE), IV acetaminophen (APAP) (low SOE), or nonsteroidal anti-inflammatory drugs (NSAIDs) administered … SOE) but we found no evidence of a clinically important difference at 60 minutes (low SOE). … Opioids may cause fewer adverse events than ketamine (low SOE), primarily administered intranasally ( … compared with ketamine (low SOE), primarily administered IV.
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srdrplus.ahrq.gov/published_projects?page=46
June 23, 2021 - , qualitative bladder tumor antigen [BTA], fluorescent in situ hybridization [FISH], and ImmunoCyt; low … but results were inconsistent, and there was no difference in risk of progression or mortality (SOE: low … HIE systems were used by 38 percent of office-based physicians in 2012 while use remains low, less than … with HIE, the number of users or the number of visits in which the HIE was used was generally very low … However, use of HIE within organizations that offer it is still low.
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srdrplus.ahrq.gov/published_projects?page=20
June 27, 2021 - may increase patient satisfaction and advance directive documentation compared with usual care (SOE: Low … have little to no effect on increasing patient satisfaction or decreasing overall symptom burden (SOE: Low … Low-strength evidence also shows that collaborative care models (i.e. … We analyzed English-language studies with low or medium ROB. … Adding low-dose-rate BT to 3D-Conformal EBR and AD may reduce mortality in higher risk CLPC.
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srdrplus.ahrq.gov/published_projects?page=33
June 27, 2021 - Trials were mostly fair quality and strength of evidence was low or moderate. … (IN) with intramuscular (IM) naloxone administration (strength of evidence [SOE] for all outcomes: low … Low-strength evidence suggested that higher-concentration IN naloxone (2 mg/1 mL) is similar in efficacy … nontransport of patients following successful reversal of naloxone overdose might be associated with a low … rate of serious harms, but patients were probably at low risk for such events, and there was insufficient
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srdrplus.ahrq.gov/published_projects?page=43
June 27, 2021 - Low-strength evidence found some institutional prevention interventions, such as antibiotic prescribing … Low-strength evidence also suggests prevention programs can be sustained over several years. … Similarly, low-strength evidence suggests that lactobaccilus strains and multiorganism probiotics also … probiotics to restore colonic biodiversity and improve patient resistance to CDI or recurrence have low … Evidence on adverse effects from RCT data was generally insufficient or low strength.
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srdrplus.ahrq.gov/published_projects?page=27
June 27, 2021 - None of the RCTs were powered or designed to capture adverse events and most RCTs studied low doses of … and SNRIs caused a greater number of withdrawals due to adverse events compared with placebo (SSRIs low … A single observational study provided evidence on long term use of antidepressants (low SOE) and suggested … SOE, NNT 13) as did mirtazapine compared with paroxetine (low SOE, NNT 9). … Increasing age was associated with greater incidence of serious adverse events with escitalopram (low
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srdrplus.ahrq.gov/published_projects?page=49
June 23, 2021 - Metformin decreased low density lipoprotein cholesterol relative to pioglitazone, sulfonylureas, and … evidence (SOE) and applicability of evidence (AOE) for each outcome was rated as insufficient (I), low … The SOE and AOE were predominantly low for THR and TKR and was insufficient HFS. … Low molecular weight heparins (LMWHs) reduced PE (OR 0.48 [0.24 to 0.95], SOE: M, AOE: L), DVT (RR 0.80 … Given these inconsistencies and the small number of comparative studies and participants, the SOE is low
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srdrplus.ahrq.gov/published_projects?page=28
June 27, 2021 - For low or medium ROB studies, one reviewer extracted data and a second verified accuracy. … Of 56 eligible publications, 44 had low or medium ROB, including 32 publications of trials (7 unique … in one large trial (10 vs. 5 years, moderate SOE), but not in another smaller trial (7 vs. 5 years, low … Neither alendronate nor zoledronic acid continuation reduced risk of nonvertebral fractures (low SOE) … Low power to assess risks of incident clinical fractures.
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srdrplus.ahrq.gov/published_projects?page=14
June 27, 2022 - opioid, nonopioid pharmacologic, and nonpharmacologic treatments for specific types of acute pain (low … Risk of bias was low in one study, moderate in nine trials and five observational studies, and high in … care and comparators for rates of contraceptive use, sexually transmitted infection, and pregnancy (low … posttraumatic stress disorder, fear of partner, coercive control, self-efficacy, and safety behaviors (low
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srdrplus.ahrq.gov/published_projects?page=50
June 23, 2021 - Results: Overall, literature was sparse and strength of evidence was generally low due to small sample … READ MORE Published on June 23, 2021 Treatment To Prevent Fractures in Men and Women With Low Bone Density … systematic review on the effectiveness and safety of treatments to prevent fractures in persons with low … The level of evidence is low to moderate for fracture risk reduction in postmenopausal women with osteopenia … The evidence is low for benefits of treatment for other populations, including men; for the benefits
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srdrplus.ahrq.gov/published_projects?page=13
September 14, 2022 - We summarized basic study characteristics for included
studies and outcomes for studies assessed as low … comparator criteria to undergo risk of bias assessment; however only nine studies
were assessed as low … Low-strength
evidence shows transition clinics may not improve hemoglobin A1C levels either at 12 or … second investigator reviewed all studies that the machine learning classifier did not classify as very low … One new trial provided low strength of evidence that TENS may be associated with improved short-term
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srdrplus.ahrq.gov/published_projects?page=16
July 29, 2022 - their THC to CBD ratio and categorized them as high-THC to CBD ratio, comparable THC to CBD ratio, and low-THC … The strength of evidence (SOE) was low, unless otherwise noted. … Evidence on whole-plant cannabis, topical, low-THC to CBD, other cannabinoids, comparisons with active … Low to moderate strength evidence suggests small to moderate improvements in pain (mostly neuropathic
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srdrplus.ahrq.gov/published_projects?page=52
March 07, 2023 - outcome below:
Symptoms: The strength of evidence for all head-to-head comparisons of FGAs and SGAs was low … Other short- and long-term outcomes: All head-to-head comparisons had low or insufficient strength of … Adverse events: All outcomes comparing FGAs with SGAs had low or insufficient strength of evidence.
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srdrplus.ahrq.gov/published_projects?page=18
October 06, 2021 - difference in overall survival (hazard ratio [HR], 1.09; confidence interval [CI], 0.69 to 1.73; 4 RCTs; low … evidence [SoE]) or death due to brain metastases (relative risk [RR], 0.93; CI, 0.48 to 1.81; 3 RCTs; low … differences across interventions in serious adverse events radiation necrosis, fatigue, or seizures (all low
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srdrplus.ahrq.gov/published_projects?page=9
January 17, 2023 - Based on pooled analysis of 11 primary CVD prevention trials using aspirin ≤100 mg/day, low-dose aspirin … Based on 4 low-dose aspirin trials (N=86,137) recruiting primary CVD prevention populations, there was … Two low-dose aspirin RCTs (N=59,020) in primary CVD prevention populations report CRC mortality during … Low-dose aspirin is associated with a 31 percent increase in intracranial bleeding events (k=11; N=134,470 … Conclusions: In primary prevention populations, low-dose aspirin reduces major CVD
events, MI and ischemic