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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
    October 01, 2020 - moderate strength of evidence [SoE]) and may increase appropriate management versus clinical diagnosis (low … Misdiagnoses on CT may not increase the risk of poor clinical outcomes (low SoE). … The significance of incidental findings is unclear (low SoE). … uncomplicated acute diverticulitis, outpatient management may be as effective as inpatient care (low … Colonoscopy: There is low SoE that patients with recent acute diverticulitis may be at about 3 times
  2. effectivehealthcare-admin.ahrq.gov/products/anal-cancer-treatment/research
    March 01, 2025 - Low   Acute GU toxicity 1 RCT; n=585 No significant difference, imprecise estimates Low   Overall late … Low   CRT with 5FU plus MMC vs. … Low   CRT with 5FU plus MMC vs. … Low: Low confidence that the evidence reflects the true effect; further research is likely to change … in late harms (low SOE).
  3. effectivehealthcare-admin.ahrq.gov/products/thromboembolism-update/research-2017
    January 01, 2021 - Most studies evaluated low molecular weight heparin (LMWH), not low-risk interventions (such as aspirin … Higher dose FXaI has lower total VTE risk (low SoE). … For TKR: LMWH has lower DVT risks than VKA (low to high SoE), but VKA has less major bleeding (low SoE … bleeding (low SoE) and more study-defined serious adverse events (low SoE). … Higher dose FXaI has lower risk of various VTE outcomes (low to moderate SoE).
  4. effectivehealthcare-admin.ahrq.gov/products/radiation-therapy-bone-metastases/research
    December 01, 2023 - SOE Harms/AEs — Toxicity, Acute Grade 3, 4 Any time None   low SOE           Delivery techniques for … SOE Skeletal Function (SINS) ≥12 weeks None 1 RCT, N=229 low SOE Quality of Life Post-RT to 26 weeks … , 95% CI 0.18 to 16.75, I 2 =74.6% low SOE Harms/AEs — SCC; Pain Flare Post-RT and 26 weeks None   low … , Not Reported None 1 RCT, N=298 low SOE           EBRT plus bisphosphonate vs. … Low: Low confidence that the evidence reflects the true effect; further research is likely to change
  5. effectivehealthcare-admin.ahrq.gov/products/osteoporosis-vibration-therapy/research-protocol
    December 01, 2019 - Background and Objectives Osteoporosis is a disease of the skeletal system characterized by low … in the U.S. 3 In addition, 49 percent of older women and 30 percent of elderly men in the U.S. have low … and 77 percent of vertebral fractures. 10 Despite proven effectiveness, these treatments may have lowlow BMD. … Low magnitude mechanical loading is osteogenic in children with disabling conditions.
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
    July 01, 2024 - or very low; COE was moderate or high for only a few comparisons (see Table A). … COE), but may result in more adverse effects (AEs) (low COE). … Bazedoxifene may improve QoL less than placebo (low COE). … in little to no difference in MBS (low COE). … Er:YAG laser compared with sham laser may result in little to no difference in QoL (low COE).
  7. effectivehealthcare-admin.ahrq.gov/products/omega-3-maternity/research
    April 01, 2021 - Birth weight and risk for low birth weight Changes in maternal n-3 FA biomarkers were significantly … birth weight (low SoE). … Prenatal EPA plus DHA or alpha-linolenic acid (ALA) supplementation had no effect on birth weight (low … DHA, EPA, or DHA-enriched fish oil supplementation had no effect on risk for peripartum depression (low … Visual acuity Prenatal supplementation with DHA had no effect on development of visual acuity (low
  8. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
    February 01, 2012 - SGA (3 RCTs, 1 PCS) Low No significant difference. symptoms Clozapine vs. olanzapine Low No significant … Low No significant difference. (2 RCTs, 1 PCS) Haloperidol vs. risperidone Low No significant difference … Low No significant difference. (1 RCT, 1 PCS, 1 RCS) Clozapine vs. risperidone Low No significant difference … ) Low No significant difference. … Olanzapine vs. risperidone Low No significant difference. (4 RCTs, 1 PCS) SGA vs. placebo (2 RCTs) Low
  9. effectivehealthcare-admin.ahrq.gov/products/stem-cell-children/research
    December 01, 2019 - The strength of evidence for specific indications was graded as high for 2 indications, moderate or low … of MPS (mucopolysaccharoidosis) II (Hunter's disease) compared to enzyme-replacement therapy (ERT) (low … no benefit of HSCT for neurodevelopmental symptoms: Gaucher Type III compared to ERT (low strength … Severe form of MPS II (Hunter's disease) compared to symptom management or disease natural history (low … survival: Nonanaplastic mixed or unspecified ependymoma compared to conventional therapy (both low
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-270-bimp-executive-summary.pdf
    May 01, 2024 - and education alone may also improve migraine-related disability (strength of evidence [SOE]: All low … with chronic migraine, behavioral sleep modification may reduce headache frequency at 6 weeks (SOE: low … the impact was 18 points on the Migraine Disability Assessment [MIDAS] scale, 95% CI 7 to 30; SOE: low … relaxation training (1 trial, difference in migraine days/month of -2.2, 95% CI -4.4 to -0.1; SOE: low … one trial, pediatric MIDAS [PedMIDAS] difference -11, 95% CI -20 to -2) than education alone (SOE: low
  11. effectivehealthcare-admin.ahrq.gov/products/diverticulitis/research
    January 01, 2022 - Misdiagnoses on CT may not increase the risk of poor clinical outcomes (low SoE). … The significance of incidental findings is unclear (low SoE). … With low SoE, among patients with recent diverticulitis, those who undergo colonoscopy may, ultimately … Incidental findings on CT may be common (low SoE), but their clinical significance is unclear. … For patients with uncomplicated acute diverticulitis, there is low SoE that antibiotic treatment does
  12. effectivehealthcare-admin.ahrq.gov/products/major-joint-replacement/research
    October 01, 2022 - Prehabilitation prior to TKA may not increase the risk of harms (low SoE). … phase may result in comparable strength (low SoE). … There was no evidence of an increased risk of harms due to prehabilitation (low SoE). … SoE) but result in similar strength when delivered in the post-acute phase (low SoE). … As a result, the evidence is largely insufficient or of low SoE.
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/joint-replacement-evidence%20-summary.pdf
    November 01, 2021 - lead to comparable outcomes of pain, range of motion, and activities of daily living (ADL) after TKA (low … o Prehabilitation prior to TKA may not increase the risk of harms (low SoE). … the acute phase after TKA (initiated within 2 weeks of surgery) may result in increased strength (low … phase may result in comparable strength (low SoE). … Prehabilitation prior to TKA may not increase the risk of harms (low SoE).
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-evidence-summary-updated-1.pdf
    October 01, 2021 - IBR may also pose a greater risk of breast seroma (Low SoE). … Silicone or saline implants may result in clinically comparable patient satisfaction with breasts (Low … submuscular plane may not impact the risk of infections that are not explicitly implant-related (Low … On the other hand, IBR may be associated with greater risk of seroma (Low SoE). … SoE) and risk of necrosis (Low SoE), but TRAM probably poses greater risk of harms to the area of
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-194-evidence-summary-corticosteroids-asthma.pdf
    October 01, 2017 - (low SOE) Intermittent ICS vs. … – Hospitalization (low SOE) – Rescue medication use (low SOE) Intermittent ICS vs. no therapy • No … SOE) – Asthma control scores (low SOE) – Spirometry (low SOE) – QOL (low SOE) Adding LAMA to ICS … SOE) – Death (low SOE) – Asthma control scores (low to high SOE) – Spirometry (low to high SOE) … – QOL (low to high SOE) – Rescue medication use (low SOE) Adding LAMA to ICS and LABA vs.
  16. effectivehealthcare-admin.ahrq.gov/products/breast-reconstruction-mastectomy/research
    March 01, 2022 - IBR may also pose a greater risk of breast seroma (Low SoE). … Silicone or saline implants may result in clinically comparable patient satisfaction with breasts (Low … Moderate SoE) and may increase the risk of infections not explicitly related to the implants or ADM (Low … well-being, psychosocial well-being, sexual well-being, and patient satisfaction with breasts (all low … Silicone and saline implants may result in clinically comparable patient satisfaction with breasts (low
  17. effectivehealthcare-admin.ahrq.gov/products/breast-biopsy-update/clinician
    December 01, 2019 - Low: [evidence low] Low confidence that the evidence reflects the true effect. … [evidence low] Specificity of automation is better. … [evidence low] Table 4: Complications Associated With Core-Needle Breast Biopsy Outcome … ] Bleeding 1.21 (0.33–3.97) [evidence low] Bleeding requiring treatment 0.00 (0.00– … 0.14) [evidence low] Infection 0.00 (0.00–0.33) [evidence low] Vasovagal reaction
  18. effectivehealthcare-admin.ahrq.gov/health-topics/hypoglycemia
    April 19, 2016 - Z Health Topics Hypoglycemia Description Hypoglycemia means low … If it doesn't, you have hypoglycemia, and your blood sugar can be dangerously low. … You can also have low blood sugar without having diabetes. … The kind of treatment depends on why you have low blood sugar.
  19. effectivehealthcare-admin.ahrq.gov/health-topics/bone-diseases
    August 29, 2023 - Different kinds of bone problems include Low bone density and osteoporosis , which make your bones … Systematic Review Archived March 28, 2012 Treatment To Prevent Fractures in Men and Women With Low … May 14, 2010 Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low … December 17, 2007 Comparative Effectiveness of Treatments To Prevent Fractures in Men and Women With Low
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hnhc-evidence-summary.pdf
    October 01, 2021 - • We found moderate to low strength of evidence (SOE) that emergency department (ED)–based, primary … care–based, and home-based care models are associated with reduced use of healthcare services; low … SOE) or ambulatory care sensitive condition ED visits (low SOE). … ), while telephonic/mail models resulted in no difference (low SOE). … ED models were also associated with lower ED costs (low SOE) but no change in inpatient costs (low SOE

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