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Total Results: 2,422 records

Showing results for "low".

281. Research White Paper - Assessing the Predictive Validity of Strength of Evidence Grades: A Meta-Epidemiological Study (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper.pdf
     September 01, 2015 - In addition, many low or insufficient grades appear to be too strict. … , and 15 percent (n=24) as insufficient (very low) SOE. … , low 47%, very low 17%) <0.001 <0.001 <0.001 Expected proportions lower-ranges (high 86%, moderate … 61%, low 31%, very low 1%) <0.001 <0.001 <0.001 Expected proportions using best fitting values (high … 86%, moderate 71%, low 60%, very low 33%) 0,1448a 0,0421 0,0925a * Lack of statistical significance

282. Long-Term Drug Therapy and Drug Holidays for Osteoporotic Fracture Prevention (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
     October 05, 2018 - Background and Objectives for the Systematic Review Osteoporosis is a skeletal disorder of low bone … years or older have osteoporosis.[3] About 2 million U.S. adults experience an osteoporotic or other low … postmenopausal women without osteoporosis, even in those who had heightened fracture risk because of low … †Osteopenia/low bone mass defined by hip or lumbar spine DXA BMD T-score < -1.0 and > -2.5. … Additional data will be extracted from studies assessed as having low to moderate risk of bias.

283. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
     March 01, 2011 - Therefore, most comparisons for this key question had a low strength of evidence. … Based on a single RCT with moderate risk of bias, we found low strength of evidence that the risk of … Except for fractures, the majority of the evidence was graded as low strength because the availability … Low Metformin plus GLP-1 agonists decreased weight to a greater extent than did several combination … Low = Low confidence that the evidence reflects the true effect.

284. Emerging Approaches to Diagnosis and Treatment of Non–Muscle-Invasive Bladder Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/bladder-cancer-non-muscle-invasive/research
     December 01, 2019 - qualitative bladder tumor antigen [BTA], fluorescence in situ hybridization [FISH], and ImmunoCyt™; low … but results were inconsistent, and there was no difference in risk of progression or mortality (SOE: low … effective across subgroups defined by tumor stage, grade, multiplicity, recurrence status, and size (SOE: low … symptoms in 27% to 84% of patients, macroscopic hematuria in 21% to 72%, and fever in 27% to 44%) (SOE: low … Compared with MMC, BCG was also associated with an increased risk of local adverse events and fever (SOE: low

285. Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m² | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/weight-loss-surgery/research
     December 01, 2019 - Improvements in hypertension, low-density lipoprotein (LDL) cholesterol, and triglycerides were also … Short-term rates of adverse events associated with bariatric surgery were relatively low. … The strength of evidence for BPD is rated low because there are fewer studies, and these have smaller … Short-term adverse events are relatively minor; strength of evidence is low due to small sample size … with low power to detect rare events.

286. Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers; Long-Term Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/adhd/research
     December 01, 2019 - A single "good" quality study of methylphenidate (MPH) with 114 preschool children provided low SOE for … Evidence from the single "good" quality study of MPH demonstrated low SOE for reduction of symptoms, … Evidence from the single "good" quality study of atomoxetine demonstrated low SOE for reduction of symptoms … quality study of combined psychostimulant medication with behavioral/psychosocial interventions provided low … risk for ADHD was high, while the SOE for methylphenidate for improved behavior among preschoolers was low

287. Management of Gout | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/gout/research
     March 01, 2020 - Moderate-strength evidence supports the finding that low-dose colchicine is as effective as higher-dose … However low-strength evidence supports the finding that treating to a specific target serum urate level … Low-strength evidence supports treating to a specific target serum urate level to reduce the risk of … High-strength evidence supports the finding that prophylactic therapy with low-dose colchicine or low

288. Telehealth for Women’s Preventive Services | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/telehealth-women/research
     January 01, 2023 - long-acting reversible contraception) at 6 months, sexually transmitted infection (STI), and pregnancy (all low … of partner, coercive control, self-efficacy, post-traumatic stress disorder, and safety behaviors (low … Risk of bias was low in one study, moderate in nine trials and five observational studies, and high in … care and comparators for rates of contraceptive use, sexually transmitted infection, and pregnancy (low … post-traumatic stress disorder, fear of partner, coercive control, self-efficacy, and safety behaviors (low

289. Binge-Eating Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/binge-eating_executive.pdf
     December 01, 2015 - Low strength of evidence suggests that we have low confidence that the evidence reflects the true effect … The number of serious adverse events was extremely low. … for BMI Low for no difference 2 RCTs (N = 162) No difference for symptoms of depression Low for no … 122) CBT increased binge abstinence Low for benefit 2 RCTs (N = 122) CBT decreased binge frequency Low … in BMI Low for no difference 2 RCTs (N = 164) No difference in symptoms of depression Low for no difference

290. Therapies for Clinically Localized Prostate Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-therapies-update/clinician
     December 01, 2019 - placing seeded radioactive material in or near the tumor Cryotherapy A strategy that uses very low … significantly lower in patients undergoing RP when compared with patients treated with EBRT.( [evidence low … patients treated with 3D-CRT plus ADT when compared with those treated with 3D-CRT alone.( [evidence low … patients treated with 3D-CRT plus ADT when compared with those treated with 3D-CRT alone.( [evidence low … Low: [evidence low] Low confidence that the evidence reflects the true effect.

291. Microsoft Word - finapps.doc (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes-2007.pdf
     January 01, 2007 - Low- profile stent placement with the monorail technique for treatment of renal artery stenosis: midterm … /19E RCT Multiple regimensF 73 0% (25) 1992-1995 BP Δ = -7/-1 p=NS/0.04 (net) CrCl Δ = 0 NS (net) Low … 159/91 ~79% 37 0 29% 71% 52% 48% Retro Multiple regimensL [1.4] 27% (37) 1996-2002 1-60 mo P<0.05 Low … pressure control” (NS) No difference in dialysis-free survival or change in GFR (NS) 67% NSP Low … See mortality figure Low Marone, 200490 nd Both cohorts ≥ 75% Cohort 1: 139 (139) Ostial: nd

292. Disposition of Comments: Comparative Effectiveness Review No. 273_Treatment of Stages I-III Squamous Cell Anal Cancer: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-273-anal-cancer-disposition-comments.pdf
     August 20, 2024 - common issue cited by one reviewer was trying to infer noninferiority of newer interventions from low-powered … #2; Rachel Riechelmann Discussion and Conclusions "Therefore, despite the vast amount of low-quality … outcomes while minimizing treatment-related toxicities." -> I think it is unfair to say “vast amount of low-quality … We have revised the sentence by rephrasing it as “low to moderate quality data”. … SCCA is not rare in many low-income countries and RCT could be conducted there.

293. Prostate-Cancer-Therapies-Update Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_executive.pdf
     December 01, 2014 - Although a single trial, the study was precise with a low risk of bias, which allowed a low strength-of-evidence … Consistency unknown (single study) Direct Precise Low Table A. … Consistency unknown (single study) Direct Precise Low EBRT vs. … strength) only if that RCT had precise findings and was rated as low risk of bias. … Low risk prostate cancer in men >/= 70 years old: to treat or not to treat.

294. Making Healthcare Safer IV: Summary of Findings on Patient Safety Practices and Ratings by a Technical Expert Panel, 2023-2024 | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/summary-findings
     December 01, 2024 - Contact precautions have mixed evidence in the endemic setting at reducing MDRO infections (low SOE). … Cohorting may be part of an effective strategy to reduce MDRO infections in an outbreak (low SOE). … Environmental decontamination may reduce MDRO infections (low SOE). … Modifying RRS can reduce mortality and arrest incidence in adults (low SOE), but effects are unclear … The TEP noted the consistent albeit low SOE for a benefit in adult populations.

295. High-Cholestorol-Medicines-Update Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_executive.pdf
     February 01, 2014 - However, all other comparisons and outcomes had low or insufficient evidence. … LDL-c and raises HDL-c than high-potency statin monotherapy (SOE: low). … mid-potency statin monotherapy (SOE: moderate and low, respectively). … HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. … Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy.

296. McCormack-notes-151008 copy - Teresa (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/mccormack-presentation.pdf
     November 12, 2015 - McCormack-notes-151008 copy - Teresa My talk today is about engaging patients with  low health   … But all of us are at risk of low health literacy at one time or another. … I do think that they are one way to help  with  low health  literacy. … This is particularly important for low literacy individuals. 12 Pictographs can  be appropriate … Sometimes that is all you’regoing to get to convey to people with  low health  literacy.

297. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 2 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
     March 01, 2022 - risk of sedation (SOE: low; 3 RCTs); potential large increased risk of nausea (SOE: low; 2 RCTs) … Cannabis Use and Low-Back Pain: A Systematic Review. … Enhancing acupuncture by low dose naltrexone. … Low-dose vaporized cannabis significantly improves neuropathic pain. … Cannabidiol in low back pain: scientific rationale for clinical trials in low back pain.

298. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
     January 01, 2007 - No differences in radiographic changes: Low Sulfasalazine vs. … risk for rare but severe adverse events: In patients who had failed initial RA treatment, greater Low … Better outcomes with the combination strategies for functional capacity: Low for each individual … remission, and less radiographic progression in the combination therapy group: Low 4 5 Summary … : Low Biologic DMARD plus Better clinical response rates, functional capacity, and No differences in

299. Nonpharmacologic Interventions for Agitation and Aggression in Dementia | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/dementia-agitation-aggression/research
     December 01, 2019 - similar to usual treatment or attention control at managing agitation/aggression in people with dementia (low-strength … interests, or both were similar to usual care in managing agitation/aggression in people with dementia (low-strength … person-centered care) were similar to usual care in managing agitation/aggression in people with dementia (low-strength … targeting caregiver skills and behavior were similar to attention control in managing agitation/aggression (low-strength

300. Prevention in Adults of Transmission of Infection With Multidrug-Resistant Organisms | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prevention-infection-mdro/rapid-research
     October 01, 2024 - systematic reviews were of good or fair quality, strength of evidence for the conclusions was always low … or very low, due to reliance on observational studies. … characteristics including a supportive organizational culture, though again strength of evidence was low … certain subpopulations (such as intensive care unit patients), though overall strength of evidence was low