-
effectivehealthcare-admin.ahrq.gov/products/fatty-acids-cardiovascular-disease/clinician
January 01, 2020 - This population exhibited a comparatively low rate of CV mortality and consumed a greater than average … Second, they cause small increases in both high-density lipoprotein cholesterol (HDL-c) and low-density … Evidence is low or insufficient to permit conclusions about the effects of or associations between DHA … EPA or DPA : Evidence was low or insufficient to permit conclusions about the benefit of EPA or DPA, … Low: [evidence low]
Low confidence that the evidence reflects the true effect.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - adults with chronic pain (e.g., neuropathic pain,
fibromyalgia, osteoarthritis, inflammatory arthritis, low … Improved pain with
capsaicin patch
compared with placebo
(SOE: Low)*
KQ1. … Effect of nortriptyline
(SOE: Insufficient)
Low back pain KQ1. … Efficacy and safety of
duloxetine in osteoarthritis or chronic low
back pain? … Effect of low-dose amitriptyline on low back
pain with a neuropathic component: a post
hoc analysis
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
November 01, 2023 - resulted in positive outcomes for a reduction in drinking days and in
heavy drinking days, resulting in low … • Since the last report, the addition of 11 new studies of baclofen have demonstrated
low strength … of evidence for reducing return to any drinking and studies of
gabapentin demonstrated low strength … Other medications that demonstrated low strength of evidence for benefit in
at least one consumption … on two studies, and in the topiramate studies, we found low strength of evidence for no
effect on
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/lumbar-fusion-protocol.pdf
June 20, 2024 - Management of symptomatic degenerative low-grade lumbar
spondylolisthesis. … Part 13: injection therapies, low-back pain, and
lumbar fusion. … • Chronic LBP: Low back pain lasting longer than 12 weeks. … Low Back Pain/ or Back Pain/ or Pain, Intractable/
2. Chronic Pain/
3. … ("low back" or lumbar).tw,kf.
5. (2 or 3) and 4
6. 1 or 5
7. Nerve Block/
8.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
January 01, 2020 - BMD, and individuals at risk for low BMD or
osteoporosis. … Three studies focused on children and adolescents with low BMD. … BMD, or are at risk for
low BMD. … at risk for osteoporosis or low BMD. … low
BMD.
-
effectivehealthcare-admin.ahrq.gov/products/fatty-acids-cardiovascular-disease/research
January 01, 2020 - Total n-3 FA : There is low strength of evidence (SoE) of no association between total n-3 FA intake … density lipoprotein cholesterol (HDL-c), and lowers the ratio of total cholesterol to HDL-c but raises low … There is low SoE of no association with CHD death, total stroke, hemorrhagic stroke, or angina pectoris … Marine oil FA individually : There is low SoE of no associations between EPA or DHA intake (separately … There is low SoE of no association between EPA biomarkers and atrial fibrillation, but moderate SoE of
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/inguinal-hernia_executive.pdf
August 01, 2012 - Odds ratio, 0.70 (CI, 0.55 to 0.88)
Low
Wound infection Favors lap. … OPM
Short-term pain Low
Mesh plug vs. PHS Short-term pain Moderate
Lichtenstein vs. … Kugel
Short-term pain Low
Lichtenstein vs.
Kugel
Intermediate-term pain Low
TAPP vs. … Long-term pain Low
PP vs. low-weight
PP
Long-term pain
(≥6 months)
Low
PP vs. combination
materials … (≥6 months), VAS on
movement
Low
Tacks or staples vs.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-app-e.xlsx
January 01, 2021 - Attrition Low and/or Adherence High? … conflicts reported Medium
Demaerschalk 2012 Yes Yes Yes Yes Yes Yes Yes Yes Yes No conflicts reported Low … Yes Yes Yes Not reported Medium
Yan 2021 Yes Yes Yes Yes Yes Yes Yes Yes Yes No conflicts reported Low … No/Low Loss to Followup or Attrition? Outcomes Prespecified and Reported? … No/Low Loss to Followup or Attrition? Outcomes Prespecified and Reported?
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/coronary-artery-disease-testing_executive.pdf
March 01, 2011 - or low risk for CAD? … Low Pretest Risk of CAD
A total of two RCTs were identified in populations with
a low pretest risk … pretest risk finished with low post-test risk. … - or high-risk patients in one trial,19 but
strength of evidence was low. … Patient
populations
There is a paucity of studies on patients with
low or very low pretest probability
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_research-protocol.pdf
January 01, 2020 - Background and objectives
Osteoporosis is a disease of the skeletal system characterized by low bone … in the U.S.3 In
addition, 49 percent of older women and 30 percent of elderly men in the U.S. have low … 2020, approximately half of all elderly Americans will be
at risk for fractures from osteoporosis or low … low BMD. … Low magnitude mechanical loading is
osteogenic in children with disabling conditions.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asthma-provider-adherence_executive.pdf
May 01, 2013 - However, our confidence
in this conclusion is low (low strength of evidence). … SOE low.
No benefit (for missed
school days).
SOE low. … Benefit with low
magnitude of effect.
SOE low. … SOE low.
No benefit.
Low SOE.
Unable to draw
conclusions. … SOE low.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-3.pdf
August 01, 2022 - risk Low risk Low risk Low risk Low risk Low risk
Friedman, 20207 Moderate risk Moderate risk Low risk … Low risk Low risk Low risk
Hodgson, 20219 Low risk Low risk Low risk Low risk Low risk Low risk … risk Moderate risk Low risk Low risk Low risk Low risk
Kandil, 202011 Moderate risk Low risk Low risk … Low risk Moderate risk Low risk
Lipton, 202112 Low risk Low risk Low risk Low risk Low risk Low risk … risk Low risk Low risk Low risk
Sakai, 202116 Low risk Low risk Low risk Low risk Low risk Low risk
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
September 01, 2014 - Low Unclear High High Low Low Yes Yes No Moderate
PVR Low Unclear High High Low Low Yes Yes No Moderate … Gallien
20054
UTI Low Low Low Unclear Low Low Yes Yes Yes Moderate
IPSS Low Low Low Unclear Low … Low Yes Yes Yes Moderate
PVR Low Low Low Unclear Low Low Yes Yes Yes Moderate
Ghalayini
20055 … Unclear Low Low Yes No No Moderate
de Sèze
20027
PVR Low Unclear Low Unclear Low Low Yes Yes No … High Low High Unclear Low Low Yes No No Moderate
PVR,
adjusted
High Low High Unclear Low Low
-
effectivehealthcare-admin.ahrq.gov/products/alcohol-misuse-drug-therapy/policymaker
January 01, 2021 - N = number; SOE = strength of evidence
a This column only includes studies rated as having a low or … medium]
Disulfiram vs. placebo
Return to any drinking
2
492
No difference
[evidence low … Naltrexone injection vs. placebo
Return to any drinking
2
939
No difference
[evidence low … ]
Return to heavy drinking
2
615
No difference
[evidence low]
Percentage of heavy … Low: [evidence low]
Low confidence that the evidence reflects the true effect.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-march-2023-grand-rounds-slides.pdf
January 01, 2023 - • Similar lengths of hospital stay
– Low SOE; 5 studies; N=1974
• Similar rates of transfers
– … Low SOE; 2 studies; N=762
• Care for neonates at rural hospitals vs. … transfer to hospital with a Level 4 newborn
intensive care
• Similar clinical outcomes
• Low SOE; … – Some improvement in medication adherence and treatment response for patients with
depression
• Low … SOE; 4 studies; N = 2030
• Similar time to treatment
– Low SOE; 7 studies; N= 3443
• Telehealth
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_executive.pdf
January 01, 2014 - noninvasive stress testing—has been proven to reduce
death or MI.8-11 For the minority of patients at low … or high dose)
Aspirina
(low or high dose)
Aspirina
(low or high dose)
Intravenous antiplatelet … In some cases, high, moderate, or
low ratings were impossible or imprudent to make
(e.g., when no … (low SOE for both outcomes). … bHRs less than 1 favor high-dose aspirin; HRs greater than 1 favor low-dose aspirin.
Table L.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/autoimmune-disease-rapid-research.pdf
September 04, 2024 - Low Low Low Low Low Low Good
Khare 2016 Some Low Low Low Low Some Some Fair
de Pablo 2022 Some High … High Low Low Low High Poor
Thilagar 2022 High High Low Low Low Low High Poor
Nguyen 2021 Low High … Low Low Low Low Low Low Low Good
Yarkac 2019 Low Low Low Low Low Low Low Good
RCT of patients with … SLE
Maybodi 2022 Some Low Low Low Low Low Some Fair
Figure D3. … Low Low Low Serious Low Serious Poor
Atarbashi-Moghadam
2018 Moderate Serious Low Serious Serious
-
effectivehealthcare-admin.ahrq.gov/products/health-equity-preventive/research
January 01, 2021 - Evidence is low or insufficient for effects of population barriers, including insurance, access, age, … Evidence is low or insufficient for other interventions due to lack of studies or their limitations. … studies evaluated effects of provider-specific barriers; 18 studies of population barriers provided low … , low health literacy, country of origin, and attitudes. … Evidence is low or insufficient to determine effects of barriers or effectiveness of other interventions
-
effectivehealthcare-admin.ahrq.gov/products/osteoporosis-fracture-prevention/research
January 01, 2020 - For studies with low or medium risk of bias, one investigator extracted data and a second verified accuracy … holiday inconsistently reduced incident vertebral fracture outcomes (radiographic only for zoledronate [low … SOE], clinical only for alendronate [moderate SOE]), but did not reduce nonvertebral fractures (low … SOE) and osteonecrosis of the jaw (low SOE in 2 comparisons, insufficient in 1). … Trials often had low power for incident clinical fractures.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
March 01, 2012 - Comparative Effectiveness Review
Number 53
Treatment To Prevent Fractures in Men
and Women With Low … Approximately
52 million people in the United States
are affected by osteoporosis or low
bone density … Low = Low confidence that the evidence reflects the
true effect. … Evidence is low for this
conclusion. … Vitamin D
Low-Moderate
The effect of vitamin D on fracture risk is uncertain.