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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/effect-protein-intake-executive-summary.pdf
November 01, 2024 - Among these, 13 studies rated as low to moderate risk of bias were synthesized. … This analytic set included five bone disease studies (3 randomized controlled trials in
adults [2 low … in adults [moderate
risk of bias], and 1 randomized controlled trial in children and adolescents [low … The evidence was insufficient to address the Key Questions, with only a few studies
rated as low to … Further, by focusing
only on studies rated low to moderate risk of bias, we limited the size of our
-
effectivehealthcare-admin.ahrq.gov/products/care-interventions-pwd/report
August 01, 2023 - discrete adaptations of REACH II) on informal caregiver quality of life at 6 months was reported as “low … (low-strength evidence)
Collaborative care models (i.e. … (low-strength evidence) The literature does not allow for further determination of whether the very small … adapted to other race/ethnic cultures within the United States, rural communities/communities with low … Low-strength evidence shows that an intensive multicomponent intervention for informal caregiver support
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
June 01, 2022 - Domingues, 20214 Low risk Low risk Low risk Low risk Low risk Low risk
Friedman, 20205 Moderate risk … Moderate risk Low risk Low risk Low risk Low risk
Hodgson, 20216 Low risk Low risk Low risk Low risk … Low risk Low risk
Hokenek, 20217 Low risk Low risk Low risk Low risk Low risk Moderate risk
Kandil … Low risk Low risk Low risk Low risk
Lipton, 202110 High risk High risk Low risk Low risk Low risk Low … Moderate risk Moderate risk Low risk Low risk Low risk Low risk
Sakai, 202113 Low risk Low risk Low
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
September 01, 2008 - Premixed insulin analogues Low The evidence was too weak to make a conclusion. … Premixed insulin analogues Low The evidence was too weak to make a conclusion. … Premixed insulin analogues Low The evidence was too weak to make a conclusion. … Nephropathy Low The evidence was too weak to make a conclusion. … Premixed insulin analogues Low The evidence was too weak to make a conclusion.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
April 01, 2021 - pregnant and postpartum women on the
benefits of pharmacotherapy; many studies report on harms but are of low … When evidence was available, we found low to moderate strength of evidence of
benefit. … We found low strength of evidence
for several outcomes. … greater than
the association between first trimester exposure to lamotrigine and the same outcomes
(low … By contrast, evidence is voluminous but of low quality on the harms of
pharmacotherapy.
-
effectivehealthcare-admin.ahrq.gov/products/childhood-depression/research
March 01, 2022 - clinician reported Adolescents with MDD CBT + TAU TAU/UC 1 212 SMD: -0.60; 95% CI: -0.87 to -0.32 low … report Adolescents with MDD Spirituality Wait-list control 1 25 SMD: -1.15 95%; CI: -1.92 to -3.20 low … Finding SOE Recovery Adolescents with MDD CBT + TAU TAU/UC 1 212 RR: 2.59; 95% CI: 1.41 to 4.74 low … Weeks to recovery Adolescents with MDD CBT + TAU TAU/UC 1 212 SMD: -0.34; 95% CI: -0.60 to -0.06 low … Low: Low confidence that the evidence reflects the true effect; further research is likely to change
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - The strength
of evidence is low. … The strength of evidence is low. … in
patients with low energy. … The strength of evidence is
low. … The strength of evidence is low.
-
effectivehealthcare-admin.ahrq.gov/products/treatments-acute-pain/research
August 01, 2022 - NSAIDs) for surgical dental pain and kidney stone pain and might be similarly effective to NSAIDs for low … Heat therapy is probably effective for acute low back pain, spinal manipulation might be effective for … (NSAIDs) for surgical dental pain and kidney stones, and might be similarly effective as NSAIDs for low … Being prescribed an opioid for acute low back pain or postoperative pain was associated with increased … Heat therapy was probably effective for acute low back pain, spinal manipulation might be effective for
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - SOE), cardiovascular mortality (low SOE), or
composite vascular events (moderate SOE). … Nonfatal stroke
SOE=Low
1 RCT, 6,452 patients
HR 0.95 (0.68 to 1.31)
No difference. … Nonfatal stroke
SOE=Low
1 RCT, 3,096 patients
HR 0.79 (0.51 to 1.22)
No difference. … SOE was
rated low across all comparisons.
Figure H. … SOE was rated low for all comparisons.
Figure I.
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effectivehealthcare-admin.ahrq.gov/products/malnutrition-hospitalized-adults/research
April 01, 2022 - Low SOE indicated that hospital-initiated malnutrition interventions may also improve quality of life … 2013, n=1193, Post-op complications, AOR: 1.60, 95% CI: 1.10 to 2.20, p<0.01 1 SR, Lew et al. 2016 low … Very Low: Very Low confidence that the evidence reflects the true effect; further research is likely … Low: Low confidence that the evidence reflects the true effect; further research is likely to change … body mass index (BMI), low skeletal muscle mass).
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/surveillance-report-2-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - adults with chronic pain (e.g., neuropathic pain,
fibromyalgia, osteoarthritis, inflammatory arthritis, low … performed dual review on all studies that the machine learning classifier
did not classify as very low … Anticonvulsants
short-term: New
evidence from
SR 2
No increased risk of SAEs
• SOE: Low, based … Efficacy and safety of
duloxetine in osteoarthritis or chronic low
back pain? … Effect of low-dose amitriptyline on low back
pain with a neuropathic component: a post
hoc analysis
-
effectivehealthcare-admin.ahrq.gov/products/anxiety-children/research-2017
January 01, 2020 - Tricyclic antidepressants marginally improved clinical response (low SOE). … Benzodiazepines did not show significant improvement in primary anxiety symptoms (low SOE). … Data on head-to-head comparisons across drugs were sparse (only 2 RCTs; low SOE). … anxiety symptoms (clinician, child, and parent report), function, remission, and clinical response (low … Medications increased short-term adverse events that were mostly not serious (low or moderate SOE).
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
October 01, 2016 - increased the length of gestation and birth
weight but did not decrease the risk for
preterm birth or low … birth, birth weight,
intrauterine growth retardation ([IUGR], small-for-
gestational age [SGA], and low … did not find a significant effect of
maternal n-3FA supplementation on the risk for low birth
weight … birth weight among women who were not
at risk due to a prior low-birth-weight pregnancy. … oil
supplementation
4 RCTs Low RCTs: No significant effects on risk
of low birth weight compared
-
effectivehealthcare-admin.ahrq.gov/products/osteoporosis-fracture-prevention/research-protocol
May 01, 2019 - Background and Objectives for the Systematic Review Osteoporosis is a skeletal disorder of low bone mass … †Osteopenia/low bone mass defined by hip or lumbar spine DXA BMD T-score < -1.0 and > -2.5. … †Osteopenia/low bone mass defined by hip or lumbar spine DXA BMD T-score < -1.0 and > -2.5. … †Osteopenia/low bone mass defined by hip or lumbar spine DXA BMD T-score < -1.0 and > -2.5. IV. … Additional data will be extracted from studies assessed as having low to moderate risk of bias.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bladder-cancer-muscle-invasive_executive.pdf
June 01, 2015 - Each study was rated as low,
medium, or high risk of bias.12 We rated the quality of
each RCT based … Therefore, a rating of applicability (such as high or low)
was not assigned because applicability may … A low grade indicates
low confidence that the evidence reflects the true effect;
further research is … Mortality Low
Three cohort studies found regional lymph node
dissection to be associated with lower … Recurrence,
progression
Low
Six cohort studies found that more extensive lymph
node dissection was
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
November 01, 2017 - Number
per 1,000
Tested
for 20%
Prevalencea
Sensitivityb
High
4 cross-
sectional
(1,576)
Low … positives
False
negatives
90
10
180
20
Specificityc
Moderate
4 cross-
sectional
(1,576)
Low … 0.25); short-
term benefit was
not sustained
in long-term
followup
Insufficient
307 patients Low … RCT Unknown Precise HR 1.01 (CI
0.86 to 1.18) for
death or nonfatal
MI
Moderate
2,481 patients Low … value: 97%), but less than 50 percent of patients who
screen positive actually have the condition (low
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
December 01, 2017 - (SOE: low). … (SOE: low). … followup (post-treatment
period), but the clinical importance of this difference
was unclear (SOE: low … Similarly, rates of mild exacerbations were
reduced following BT (low SOE), but concerns about the … physiology measures (FEV1 % predicted and morning
PEF [L/min]), or other asthma symptoms outcomes (low
-
effectivehealthcare-admin.ahrq.gov/health-topics/back-pain
December 17, 2020 - Chronic Pain
Clinician Summary Archived November 15, 2016
Noninvasive Treatments for Low … Evidence
Consumer Summary Archived November 15, 2016
Noninvasive Treatments for Low … Discussions
Systematic Review Archived February 29, 2016
Noninvasive Treatments for Low … Back Pain
Research Protocol Archived October 8, 2014
Noninvasive Treatments for Low
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_executive.pdf
October 01, 2012 - Moderate
Low
Moderate
Low
Low
Pain (KQ1a and KQ2a) Pain
Quality of life
Moderate
Low
Distress … (KQ1a and KQ2a) Distress
Depression
Low
Low
Communication and Decisionmaking
(KQ1a and KQ2b)
Patient … Moderate
Low
Low
Multiple and Other Targets (KQ2a) Quality of life
Satisfaction
Quality of care … Patient symptoms
Psychosocial support
Low
Low
Low
Low
Low
aStrength of evidence is based mainly … The quality of many studies was moderate to low.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - • Low—Low confidence that the evidence reflects the
true effect. … Low-air-loss beds Low Wound improvement was similar for low-air-loss beds compared with
foam surfaces … (4 studies) and for low-air-loss beds compared with
low-air-loss bed overlays (1 study).
11
Table … There was low-strength evidence that dextranomer was
less effective than wound dressings. … Efficacy of
low-level laser therapy on wound healing in human subjects: a
systematic review.