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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
    December 01, 2020 - NSAIDs) for surgical dental pain and kidney stone pain and might be similarly effective to NSAIDs for low … • Being prescribed an opioid for acute low back pain or postoperative pain might be associated with … • Heat therapy is probably effective for acute low back pain, spinal manipulation might be effective … This review focused on eight acute pain conditions: low back pain, neck pain, other musculoskeletal … Evidence was also limited for musculoskeletal pain other than low back pain and kidney stone pain.
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-rapid-research.pdf
    April 01, 2024 - Low risk High risk Low risk Low risk Unclear risk Miller et al, 202346 Low risk Unclear risk High … risk Low risk Low risk Low risk Ray et al., 201751 Unclear risk Low risk High risk Low risk High risk … Unclear risk Salgado et al., 201352 Low risk Unclear risk Low risk Low risk Low risk Unclear risk … Unclear Unclear Low Low Evans et al, 202328 Unclear Low Low High Low Low Low Martin, 201841 … Unclear Low Low Unclear Unclear Low Low Mehta et al., 201345 High High Low Unclear Unclear Low
  3. effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/antenatal-care
    December 01, 2020 - Population: women with low-risk (uncomplicated) pregnancies Interventions and Comparators: "poor" or … However, emerging evidence suggests that reducing the number of prenatal visits for low-risk women in … high, middle, and low-income countries does not increase adverse outcomes, with mixed findings about … Alternative versus standard packages of antenatal care for low-risk pregnancy. … Number of prenatal visits and pregnancy outcomes in low-risk women.
  4. effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-staging/research
    December 01, 2019 - to 0.89), and less likely to overstage (OR = 0.47; 95% CI, 0.28 to 0.80), supported by evidence of low … preoperative rectal cancer T staging, MRI and ERUS were similar in accuracy, supported by evidence of low … difference in accuracy across MRI, CT, or ERUS for interim rectal T restaging, supported by evidence of low … Conclusions ERUS is preferable to CT for preoperative rectal cancer T staging (based on evidence of lowLow-strength evidence suggests that CT, MRI, and ERUS are comparable for rectal cancer N staging, where
  5. effectivehealthcare-admin.ahrq.gov/products/c-difficile-update/research
    January 01, 2020 - Low-strength evidence was found that some institutional prevention interventions, such as antibiotic … Low-strength evidence also suggested that prevention programs can be sustained over several years. … number of new studies, the overall high risk of bias of many of these studies necessitated ratings of low … Specifically, low-strength evidence suggests that FMT may have a significant effect on reducing recurrent … Similarly, low-strength evidence suggests that lactobaccilus strains and multiorganism probiotics also
  6. effectivehealthcare-admin.ahrq.gov/products/migraine-prevention/research-2013
    December 01, 2019 - Strength of evidence was mostly low due to risk of bias and imprecision in individual RCTs and pooled … in patients with chronic migraine but failed to decrease monthly migraine frequency by ≥50 percent (low-strength … Exploratory indirect adjusted frequentist analysis offered low-strength evidence that the angiotensin … Exploratory network Bayesian meta-analysis offered low-strength evidence that angiotensin inhibiting … Individual RCTs of drug-management interventions for episodic migraine offered low-strength evidence
  7. effectivehealthcare-admin.ahrq.gov/products/lumbar-spinal-fusion
    May 01, 2024 - KQ4: Among patients with chronic low-back pain resulting from degenerative disease of the lumbar spine … spondylolisthesis who are symptomatic following conservative treatments Adult patients with chronic low … alone Alternative form of treatment of non-operative treatment or no specific treatment Measures of low … ) Rates of re-operation Harms of treatment (2A) Rates of arthrodesis (2B) Postoperative outcomes of low … Efficacy of Radiofrequency Neurotomy in Chronic Low Back Pain: A Systematic Review and Meta-Analysis.
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-fracture-prevention-evidence-summary.pdf
    April 01, 2019 - Comparative Effectiveness Review Number 218 Introduction Osteoporosis is a skeletal disorder of low … adults aged 50 years or older.2 About two million U.S. adults experience an osteoporotic or other low … (IM) NVF No difference:HR=0.88 [0.74, 1.04]; ARR=-1 [-3, 0] Low (IM) Hip No difference: HR=0.79 … [0.43, 1.44]; ARR=-0.2 [-0.8, 0.4] Low (h-IM) RVF Lower risk: HR=0.56 [0.39, 0.80]; ARR=-2 [-3, - … (RB, IM) Hip Lower risk: HR=0.55 [0.32, 0.94]; ARR= -1 [-2, 0] Low (RB, IM) 53 PM women with
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
    May 01, 2013 - Summary judgments for these studies were assigned as high risk of bias, low risk of bias, or unclear … SOE 78.1% (65.0–88.7%) Specificity 1 (276) High NA Direct Imprecise Low SOE 47.1% (40.3–59.9%) … NA Direct Imprecise Low SOE 95.2% (90.4–98.1%) Specificity 1 (617) Low NA Direct Imprecise Low SOE … for point estimates at each threshold) Specificity 1 (506) Low NA Direct Imprecise Low SOE 83–91% … Two studies were rated low risk of bias, 10 high risk of bias, and 3 unclear risk of bias.
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
    December 31, 2022 - Low Low Moderate Low High quality Goldberg24 Low Low Low Moderate Low High quality Hall9 Low … Moderate Moderate quality Jeffery- Smith31 Low Low Low Moderate Low High quality Krutikov30 … Low Moderate Low Low Low High quality Leidi38 Low Moderate Moderate Low Low High quality Lumley28 … Low Moderate Low Moderate Low High quality Manica33 Low Moderate Moderate Moderate Low High quality … Pilz34 Moderate Serious Moderate Moderate High Poor quality Rennert25 Low Low Low Low Low High
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
    September 01, 2021 - Intradiscal ozone for radicular low back pain or nonradicular, presumed discogenic back pain (protocol … No trial compared kyphoplasty against sham (SOE: low for function at 1 week; moderate for pain and … 6 months (2 trials, N=153, with conflicting results) and 12 months or longer (1 trial, N=72) (SOE: low … injection without corticosteroid or oxygen-ozone injection for presumed (nonradicular) discogenic low … and persistent pain/numbness at implantation site in 13 percent of patients (1 trial, N=157) (SOE: low
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
    January 01, 2022 - cannabidiol (CBD) ratio using the following categories: comparable THC to CBD, high-THC to CBD, and low-THC … Using a living • Evidence on whole-plant cannabis (including patient’s choice of products), low THC … Cannabinoid interventions were categorized according to their THC to CBD ratio (comparable, high, low … Strength of evidence was assessed as low, moderate, high, or insufficient, and magnitude of effect was … Risk of Bias 29% high, 57% moderate, 14% low 50% moderate, 50% low 22% high, 44% moderate, 33%
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/white-paper-roadmap-interventions.pdf
    November 01, 2020 - The strength of evidence is rated in EPC reports as high, moderate, low, and insufficient. … (avoid commenting on the magnitude of effect when the SOE is low) Strength of evidence Magnitude … ] may slightly improve/reduce [outcome] (low certainty evidence) [Intervention] may make little … Suggested statements to convey low and very low certainty of evidence Effect Size Low and Very Low Certainty … of Evidence Large effect (Low certainty of evidence) X may result in a large reduction/increase
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cognitive-decline_executive.pdf
    March 01, 2017 - Results were extracted only from studies assessed as having low to moderate risk of bias. … • Low: Limited confidence that the estimate of effect lies close to true effect. … However, there was also low-strength evidence that estrogen replacement with or without progesterone … Its results provide moderate-strength evidence at 2 years (but low-strength at 5 and 10 years) that … aspirin on MCI or CATD incidence. • Low-strength evidence shows no benefit for low-dose aspirin on brief
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cognitive-decline_executive.pdf
    March 01, 2017 - Results were extracted only from studies assessed as having low to moderate risk of bias. … • Low: Limited confidence that the estimate of effect lies close to true effect. … However, there was also low-strength evidence that estrogen replacement with or without progesterone … Its results provide moderate-strength evidence at 2 years (but low-strength at 5 and 10 years) that … aspirin on MCI or CATD incidence. • Low-strength evidence shows no benefit for low-dose aspirin on brief
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
    September 01, 2019 - : 12 Medium: 2 High: 2 Unclear: 2 Low/medium: 2 Low: 7 Medium: 1 Low: 9 Unclear: 1 Low/medium … : 1 Low: 2 Medium: 1 Table A. … Due to indirectness, strength of evidence is generally low, and future research in the prehospital … Low- dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial. … Can low-dose of ketamine reduce the need for morphine in renal colic?
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-draft-report.pdf
    January 31, 2025 - As a result, the strength of evidence is low or insufficient across outcomes. … Low Birth Weight 1 NRS 54 Similar rates of low birth weight across all groups and timepoints. … Low KQ1. … Low KQ3. … Low carbohydrate diets may increase risk of neural tube defects.
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
    October 05, 2018 - Background and Objectives for the Systematic Review Osteoporosis is a skeletal disorder of low bone … years or older have osteoporosis.[3] About 2 million U.S. adults experience an osteoporotic or other low … postmenopausal women without osteoporosis, even in those who had heightened fracture risk because of low … †Osteopenia/low bone mass defined by hip or lumbar spine DXA BMD T-score < -1.0 and > -2.5. … Additional data will be extracted from studies assessed as having low to moderate risk of bias.
  19. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
    November 01, 2020 - Precision ranged from moderate (NNR 13) to low (NNR 580). … Low Back Pain/ 16. Neck Pain/ 17. exp Arthritis, Rheumatoid/ 18. … Yoga for military veterans with chronic low back pain: a randomized clinical trial. … Efficacy of extremely low-frequency magnetic field in fibromyalgia pain: A pilot study. … Efficacy of low-dose amitriptyline for chronic low back pain: a randomized clinical trial.
  20. effectivehealthcare-admin.ahrq.gov/products/management-infantile-epilepsy/research
    March 01, 2023 - likely than the modified Atkins diet to reduce seizure frequency (SOE: low). … , low patient enrollment, and inconsistent reporting. … Low: Low confidence that the evidence reflects the true effect; further research is likely to change … Furthermore, the KD was more likely to reduce seizure frequency than the MAD (SOE: Low). … Thus, we concluded that surgery may cause seizure freedom in some infants (SOE Low).

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