-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
October 01, 2022 - and both support the conclusion that levetiracetam may cause seizure
freedom in some infants (SOE: Low … 5 pre/post studies) support the conclusion that KD may
cause seizure freedom in some infants (SOE: Low … Two RCTs support the conclusion
that a modified Atkins diet (MAD) may reduce seizure frequency (SOE: Low … RCTs comparing KD with MAD suggest that KD may cause greater reductions in
seizure frequency (SOE: Low … hemispherotomy and
non-hemispheric surgical procedures cause seizure freedom in some infants (SOE: Low
-
effectivehealthcare-admin.ahrq.gov/products/mental-health-pregnant/research
July 01, 2024 - SoE), and may increase remission rates for depressive symptoms (low SoE). … Behavioral activation may be more effective than TAU to reduce depressive symptoms (low SoE). … Low: Low confidence that the evidence reflects the true effect; further research is likely to change … However, conclusions regarding remission rates were rated low SoE. … higher with specific acupuncture than nonspecific or sham acupuncture (low SoE).
-
effectivehealthcare-admin.ahrq.gov/products/postpartum-care-one-year/research
October 01, 2023 - visit is conducted at home/by telephone or at the clinic may not impact depression or anxiety symptoms (low … clinic versus standard care) may not impact depression symptoms or substance use up to 1 year (all low … rates of exclusive breastfeeding at 3 months and nonexclusive breastfeeding at 1 and 3 months (all low … 11 NRCSs) and may be associated with fewer preventable readmissions and emergency room (ER) visits (low … (moderate SoE) and may be associated with fewer preventable readmissions and emergency room visits (low
-
effectivehealthcare-admin.ahrq.gov/products/prehospital-airway-management/research
August 01, 2021 - The following conclusions for Key Questions 1-3 were supported by low or moderate SOE (see Table A): … There was low SOE for no difference in these patients for BVM versus SGA and SGA versus ETI. … There was low SOE for all three comparisons in pediatric cardiac arrest patients, and low SOE in adult … In pediatric patients there was low SOE of no difference for BVM versus ETI and SGA versus ETI. … Low SOE also supported no difference for first-pass success in adult medical patients.
-
effectivehealthcare-admin.ahrq.gov/products/hemorrhage-postpartum/clinician
December 01, 2019 - [evidence low]
Evidence for the success of uterine balloon tamponade in controlling bleeding is … [evidence low]
The strength of evidence is insufficient for the success of uterine compression … [evidence low]
There may be an association between embolization and the occurrence of hematoma … [evidence low]
Evidence is insufficient to permit conclusions about harms associated with other … Low: [evidence low]
Low confidence that the evidence reflects the true effect.
-
effectivehealthcare-admin.ahrq.gov/products/diabetes-behavior-programs/clinician-2016
December 01, 2019 - vs. usual care
HbA 1c
End of intervention †
16
1155
↔
-0.11 (-0.33 to 0.11)
[evidence low … ) ††
[evidence medium]
12-month followup
7
1333
↔
-0.22 (-0.49 to 0.05)
[evidence low … 12-month followup
4
1138
↔
-0.40 (-0.92 to 0.12)
(>12 months to <24 months)
[evidence low … . active control §
HbA 1c
End of intervention
4
566
↔
-0.32 (-0.78 to 0.14)
[evidence low … Low: [evidence low]
Low confidence that the evidence reflects the true effect.
-
effectivehealthcare-admin.ahrq.gov/products/mhs4-failure-rescue/rapid-research
March 01, 2024 - systems may have a large impact on hospital mortality, but like adults, the strength of the evidence is low … associated with a reduction in mortality and the incidence of cardiorespiratory arrest for adults (low … primary studies, rapid response systems may have a large impact in reducing in-hospital mortality (low … reducing the incidence of cardiorespiratory arrest on hospital general wards in adult populations (low … associated with a reduction in mortality and the incidence of cardiorespiratory arrest for adults (low
-
effectivehealthcare-admin.ahrq.gov/products/tonsillectomy/research-2017
March 01, 2020 - improve sleep and reduce throat infections in the short term, which must be weighed against a relatively low … prospective and 5 retrospective cohort studies, and 53 database or registry studies or case series [67 low … of throat infections (moderate SOE) and associated health care utilization and work/school absences (low … Short-term improvements must be weighed against the risk of PTH (high SOE for low frequency of PTH). … Surgical technique had little bearing on return to normal diet or activity (low SOE).
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/lumbar-spinal-fusion-key-question.pdf
January 01, 2023 - KQ4: Among patients with chronic low-back pain resulting from degenerative disease of the lumbar
spine … treatments (KQ1-2, 4-6)
Adult patients with
degenerative disease of
the lumbar spine and
low … back pain and
Measures of low back
pain and patient
functional status
measured by ODI,
EQ5D, … and the SF-36
Neurological damage
attributable to the
surgical procedure
Measures of low back … Interventional Minimally Invasive Treatments for Chronic Low
Back Pain Caused by Lumbar Facet Joint
-
effectivehealthcare-admin.ahrq.gov/products/heart-failure-transition-care/clinician
December 01, 2019 - [evidence medium]
Mortality
3 (564)
No difference
0.93 (0.25 to 3.48)
NA
[evidence low … HF clinic
All-cause readmission
2 (264)
No difference
0.88 (0.57 to 1.37)
NA
[evidence low … Low: [evidence low]
Low confidence that the evidence reflects the true effect. … : HF-specific quality of life was greater for home-visiting programs than usual care over 3 months (low … SOE) but not at 6 months (low SOE).
-
effectivehealthcare-admin.ahrq.gov/products/partial-breast-irradiation/research
May 01, 2023 - WBI: 36.15% (47/130) low SOE Favors PBI 1 RCT 258 low SOE Cosmesis reported by patient (poor or fair … WBI: 92.66% (606/654) low SOE No difference 1 RCT 1305 low SOE Overall survival > 10 years RR: 1.01 … WBI: 86.89% (497/572) low SOE No difference 1 RCT 1153 low SOE Mastectomy-free survival > 10 years … WBI: 12.90% (144/1116) low SOE No difference 2 RCTs 2237 low SOE Cosmesis reported by patient (poor … WBI: 1.43% (5/350) low SOE No difference 2 RCTs 692 low SOE Ipsilateral Breast Recurrence 10 years
-
effectivehealthcare-admin.ahrq.gov/products/depression-harms/research
May 01, 2020 - None of the RCTs were powered or designed to capture adverse events and most RCTs studied low doses of … A single observational study provided evidence on long-term use of antidepressants (low SOE) and suggested … withdrawals due to adverse events than tricyclic antidepressants (amitriptyline or nortriptyline) (low … SOE, number needed to treat [NNT] 13), as did mirtazapine compared with paroxetine (low SOE, NNT 9). … Increasing age was associated with greater incidence of serious adverse events with escitalopram (low
-
effectivehealthcare-admin.ahrq.gov/products/nonpharma-treatment-pain/research-protocol
December 01, 2019 - chronic pain, this comparative effectiveness review focuses on five common chronic pain conditions: low … treatments and provided a comprehensive evaluation of noninvasive, nonpharmacological low back pain … KQ1: Low back pain
Adults with chronic, nonradicular low back pain
KQ2: Neck pain
Adults … For chronic low back pain, for interventions addressed in the prior AHRQ low back pain review, we will … Noninvasive Treatment for Low Back Pain. Comparative Effectiveness Review No. 169.
-
effectivehealthcare-admin.ahrq.gov/products/heart-failure-transition-care/policymaker
December 01, 2019 - [evidence medium]
Number of hospital days at readmission
3
403
Reduced
NA
[evidence low … 182
No benefit
NA
[evidence medium]
Mortality
3
564
No benefit
NA
[evidence low … 1
106
–
NA
[evidence insufficient]
Mortality
2
264
No benefit
NA
[evidence low … ]
Mortality
2
423
No benefit
NA
[evidence low]
Strength of Evidence Scale … Low: [evidence low]
Low confidence that the evidence reflects the true effect.
-
effectivehealthcare-admin.ahrq.gov/products/tethered-spinal-cord/research
March 01, 2025 - Studies reported improvement of neurological status with surgical detethering (low strength of evidence … small body of evidence exists for revision detethering and spinal column shortening for repeat surgery (low … prophylactic surgery, but it was also associated with complications such as surgical site infection (low … Studies reported improvement of neurological status after surgical detethering (low SoE), but it was … small body of evidence exists for revision detethering and spinal column shortening for repeat surgery (low
-
effectivehealthcare-admin.ahrq.gov/products/breast-abnormalities-tests-update/research
December 01, 2019 - The estimate of accuracy was judged to be supported by a moderate to low strength of evidence (low for … The estimate of accuracy was judged to be supported by a Low strength of evidence. … The estimate of accuracy was judged to be supported by a Low strength of evidence. … These estimates of accuracy were all judged to be supported by a Low strength of evidence. … on breast cancer screening, may be clinically useful for diagnostic purposes only for women with a low
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
December 01, 2020 - NSAIDs) for surgical dental pain and kidney stone pain and might be similarly
effective to NSAIDs for low … • Being prescribed an opioid for acute low back pain or postoperative pain might be
associated with … • Heat therapy is probably effective for acute low back pain, spinal manipulation
might be effective … This review focused on eight
acute pain conditions: low back pain, neck pain, other musculoskeletal … Evidence was also limited for
musculoskeletal pain other than low back pain and kidney stone pain.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-rapid-research.pdf
April 01, 2024 - Low risk High risk Low risk Low risk Unclear risk
Miller et al, 202346 Low risk Unclear risk High … risk Low risk Low risk Low risk
Ray et al., 201751 Unclear risk Low risk High risk Low risk High risk … Unclear risk
Salgado et al.,
201352
Low risk Unclear risk Low risk Low risk Low risk Unclear risk … Unclear Unclear Low Low
Evans et
al, 202328
Unclear Low Low High Low Low Low
Martin,
201841 … Unclear Low Low Unclear Unclear Low Low
Mehta et
al.,
201345
High High Low Unclear Unclear Low
-
effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/antenatal-care
December 01, 2020 - Population: women with low-risk (uncomplicated) pregnancies Interventions and Comparators: "poor" or … However, emerging evidence suggests that reducing the number of prenatal visits for low-risk women in … high, middle, and low-income countries does not increase adverse outcomes, with mixed findings about … Alternative versus standard packages of antenatal care for low-risk pregnancy. … Number of prenatal visits and pregnancy outcomes in low-risk women.
-
effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-staging/research
December 01, 2019 - to 0.89), and less likely to overstage (OR = 0.47; 95% CI, 0.28 to 0.80), supported by evidence of low … preoperative rectal cancer T staging, MRI and ERUS were similar in accuracy, supported by evidence of low … difference in accuracy across MRI, CT, or ERUS for interim rectal T restaging, supported by evidence of low … Conclusions
ERUS is preferable to CT for preoperative rectal cancer T staging (based on evidence of low … Low-strength evidence suggests that CT, MRI, and ERUS are comparable for rectal cancer N staging, where