-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-tables-f1-f2-2022-update_0.xlsx
January 01, 2022 - Unclear Yes Unclear Unclear Unclear Yes Yes Yes Moderate
Chaves,2020 Yes Yes Yes Yes Yes Yes Yes Yes Yes Low … Yes Unclear Yes Yes Yes No No Yes Moderate
Langford, 2013 Yes Unclear Yes Yes Yes Yes Yes Yes Yes Low … Yes Yes Yes Yes Yes Unclear Yes Yes No Moderate
Pini, 2012 Yes Unclear Yes Yes Yes Yes Yes Yes Yes Low … Unclear Yes Yes Yes Unclear Yes Yes Yes Moderate
Schimrigk, 2017 Yes Yes Yes Yes Yes Yes Unclear Yes Yes Low … Unclear Yes Yes Yes Yes Yes No Yes No Moderate
Toth, 2012 Yes Yes Unclear Yes Yes Yes Yes Yes Yes Low
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-app-g-table-surveillance-report-2_0.xlsx
February 16, 2022 - Unclear Yes Unclear Unclear Unclear Yes Yes Yes Moderate
Chaves,2020 Yes Yes Yes Yes Yes Yes Yes Yes Yes Low … Yes Unclear Yes Yes Yes No No Yes Moderate
Langford, 2013 Yes Unclear Yes Yes Yes Yes Yes Yes Yes Low … Yes Yes Yes Yes Yes Unclear Yes Yes No Moderate
Pini, 2012 Yes Unclear Yes Yes Yes Yes Yes Yes Yes Low … Unclear Yes Yes Yes Unclear Yes Yes Yes Moderate
Schimrigk, 2017 Yes Yes Yes Yes Yes Yes Unclear Yes Yes Low … Unclear Yes Yes Yes Yes Yes No Yes No Moderate
Toth, 2012 Yes Yes Unclear Yes Yes Yes Yes Yes Yes Low
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-pain-management-grand-rounds-slides.pptx
March 01, 2022 - no effect/no statistically significant effect), small, moderate, or large increased risk; SOE: + = low … CBD, Synthetic No evidence Insufficient (1) Insufficient (1)
Low THC – Oral CBD or CBD/THC, Unclear … Origin Insufficient (1 new) Insufficient (1 new) Insufficient (1 new)
Low THC – Sublingual CBD/THC, … versus dihydroergotamine + metoclopramide: worse pain relief and function (low SOE)
Morphine versus … relief (low SOE)
Hydromorphone versus diphenhydramine + prochlorperazine: worse pain relief (low SOE
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-addendum-140619.pdf
June 19, 2014 - o SOE for Stroke = Moderate (was Insufficient for old comparison 1
and Low for old comparison 2); one … 245
patients)
SOE=
Insufficient (1
study, 67
patients)
AF: SOE= Mixed:
Insufficient (1 SOE= Low … Transcatheter
Segmental
PVI
SOE=
Insufficient
(1 study,
80
patients)
SOE=Low (5
studies, 500 … which
did not reach
statistical
significance
SOE=
Insufficient (No
studies)
All-Cause:
SOE=Low … Transcatheter
PVI Without
CFAE
Ablation
SOE=Low
(2 studies,
247
patients)
2 studies
showing
-
effectivehealthcare-admin.ahrq.gov/products/health-literacy/research-protocol
December 01, 2019 - show the effect of interventions on low health literacy (KQ2). … We use four grades: high, moderate, low, and insufficient. … "Low literacy and mental illness in a nationally representative sample." … Latino Adults with type 2 diabetes and low literacy." … "Low literacy: a hidden problem in family planning clinics."
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0129_07-13-2009.pdf
January 01, 2009 - 6-9-10
1
Results of Topic Selection Process & Next Steps
Cesarean birth in low-risk … Staff-Generated PICO
Population(s): low-risk pregnant women with singleton pregnancy, vertex presentation … factors influence (and which have
the greatest impact on) the probability of delivery by cesarean in low-risk … Cesarean Birth in Low-Risk Women
Nomination Summary Document
http://effectivehealthcare.ahrq.gov/index.cfm … Some of the
Healthy People 2010 objectives focus on reducing cesarean births among low-risk women.
-
effectivehealthcare-admin.ahrq.gov/products/infantile-hemangioma/policymaker
December 01, 2019 - more effective
[evidence high]
Rebound growth/need for further treatment
2 studies
501
Low … Improvement in IH
Network meta-analysis
N/A
Intralesional steroids more effective
[evidence low … vs. observation
Improvement in IH
2 studies
143
Pulse dye laser more effective
[evidence low … ]
Quality of life
2 studies
143
No significant difference
[evidence low]
Long-pulse … Low: [evidence low]
Low confidence that the evidence reflects the true effect.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-244-safety-vaccines-update-evidence-summary.pdf
May 01, 2021 - We differentiated
high, moderate, low, and insufficient evidence to communicate the confidence in the … • Low: Low confidence that the evidence reflects the true effect. … Quadrivalent®, Flulaval
Quadrivalent®, Fluzone High
Dose Quadrivalent®, Fluzone
Quadrivalent®)
Low … Fluad Quadrivalent®)
Moderate: No evidence of increased risk of cardiovascular events, stroke
Low … cardiovascular events, herpes
zoster, myocardial infarction, reproductive system events, stroke
Low
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
August 01, 2016 - Over a decade ago, low-
osmolar contrast media (LOCM) replaced high-osmolar
media as the standard of … NAC plus IV saline is superior to IV saline
(alone or with placebo) (low SOE). … Low-dose NAC was
defined as 1200 mg/day or less.
�� Statins plus NAC plus IV saline (or bicarbonate) … Low: ��� Low confidence that the evidence reflects the true
effect. … d High-dose = more than 1200 mg/day; low-dose = 1200 mg/day or less.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
September 01, 2011 - ECT vs. rTMS Response rate 42 Low 1 fair trial: ECT and rTMS did not differ
significantly. … ECT plus rTMS Change in 22 Low 1 fair trial: both ECT and ECT plus rTMS
vs. … ECT
ECT plus rTMS Remission rate 22 Low 1 fair trial: ECT and ECT plus rTMS did not
vs. … rTMS vs. sham Health-related 60 Low 1 fair trail: low rTMS had significantly
outcomes greater improvement … All findings provided low strength of
evidence.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
June 01, 2017 - Unclear Low
Paradise 2001
11309632
Low Low High High High Low Low Unclear Low
NCT00629694 Unclear … Unclear High Low Low Low
NCT00162994 Unclear Unclear Low Unclear Low Unclear Unclear Unclear Low … Kujala 2012
22466327,
24445832
Low Low High High High Low Low Unclear Low
NCT01949142
and
NCT01949155 … Unclear Low Low Low Low Unclear Low Unclear Low
M air 2016
26985629
Low Low Low Low Low Low Low … Low Low Low Uncle
ar
Unclear Low Low Uncle
ar
Unclear
NCT019
08803
Unclea
r
Unclear High High
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - symptomatic DVT (low SoE). … FXaI (low SoE) … high dose
VTE, total RCT: 4 (981) 1.55 (0.78, 3.06) Favors high dose Low
LMWH low vs. … dose Low
VTE vs. … low SoE) but
risk of study-defined serious adverse events is lower
with FXaI (low SoE)
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - symptomatic DVT (low SoE). … FXaI (low SoE) … high dose
VTE, total RCT: 4 (981) 1.55 (0.78, 3.06) Favors high dose Low
LMWH low vs. … dose Low
VTE vs. … low SoE) but
risk of study-defined serious adverse events is lower
with FXaI (low SoE)
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-266-cdd-app-tabs-D2-D5.xlsx
January 01, 2008 - Yes/No/Unclear
Risk of Bias
Low/Moderate/High
Abbott, 2013 Yes Unclear Yes No No No Yes No Yes Yes … Cheung, 2019 Yes Yes Yes No No Yes - all but self-report
No - patient self-report Yes Yes Yes Yes Yes Low … AEs, adjudicated, blinded assessment) Yes Yes: 24 mos (92.2%) Yes: 24 mos (95.3% vs. 86.1%) Yes Yes Low … AEs, adjudicated, blinded assessment) Yes Yes: 48 mos (82.1%) No: 48 mos (86.2% vs. 73.9%) Yes Yes Low … Hou, 2016 Yes Yes Yes No No Yes (except PROs) Yes Yes Yes Yes Yes Low
Jackson, 2016 Yes Yes Yes No
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
January 01, 2012 - losartan low;
telmisartan vs. … Low-protein diet vs. … usual protein diet
6 trials; 1,480
patients
Mortality: low
ESRD: low
• Low-protein diet did not … Low-protein diet
vs. low-carb, low-
iron-available,
polyphenol-enriched
diet
1 trial; 191 patients … Low-protein, low-
phosphate diet vs.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0583-131115.pdf
March 13, 2013 - cyclosporine or tacrolimus at two hours after administration (C2);
immunosuppression with ATG and low … Multidrug with low tacrolimus versus standard dose tacrolimus: In renal
transplants, have multidrug … of thymoglobulin to a tacrolimus low target level anti-
rejection regimen in renal transplants? … Sensitivity of monitoring for low dose tacrolimus [not a comparative effectiveness
question; should … Sensitivity of monitoring for low dose CNIs: Are analytical capabilities sufficient to
measure CNIs
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/braddock.pdf
January 01, 2011 - Slide 1: Supporting
Shared Decision Making
When Clinical Evidence is
Low … Overview
• Ethical foundations of SDM
• Conceptual model for SDM, patient values, and evidence
• SDM in low … differences
in
knowledge between patients and physicians for these items:
• High evidence; low … 80; Patient score = 20
• High evidence; high knowledge: Physician score = 80; Patient score = 40
• Low … evidence, low knowledge: Physician score 30; Patient score = 5
• Low evidence, high
knowledge: Physician
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - Surveillance
settings
Unit of analysis:
patients with
HCC
CT Sensitivity: Low
Specificity: Low … Lesion size US with contrast Sensitivity:
Low
Specificity:
Low
Sensitivity was 0.94 (95% CI, 0.83 … CT Sensitivity:
Low
Specificity:
Low
Sensitivity was 0.81 (95% CI, 0.70 to 0.92) vs. 0.74 (95% CI … MRI
Sensitivity:
Low
Specificity:
Low
Sensitivity was 0.79 (95% CI, 0.65 to 0.94) vs. 0.83 (95% … CT Sensitivity:
Low
Specificity:
Low
One study found MRI associated with higher sensitivity (0.84
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_executive.pdf
January 01, 2010 - 1
Comparative Effectiveness Review
Number 80
Strategies To Reduce Cesarean Birth
in Low-Risk Women … There is low strength of evidence
favoring benefit for traditional trained doula support. … At times
there was low strength of evidence for lack of benefit. … the question of how best to prevent
cesarean in low-risk women at term. … Strength of evidence was low to insufficient across all
strategies.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - ) such
that the methodological quality is opposing (e.g., high
ROB represents low quality). … Summary of findings tables contain the findings
having at least low SOE. … All evidence graded as having at least low SOE
was for outcomes between SGAs and placebo. … Table F summarizes the findings for outcomes
having at least low SOE. … Low (5mg/day)
BMI (kg∙m-2) -- - - - MD, 0.03; 95% CI, -0.04 to 0.10 Low; may make little or
no differencee