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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
    April 01, 2020 - guideline, all except for one (treatment for opioid use disorder) were assessed as being supported by low … depending on: (1) the specific type or cause of pain (e.g., neuropathic, musculoskeletal [including low … depending on: (1) the specific type or cause of pain (e.g., neuropathic, musculoskeletal [including low … Effects on opioid dose were not statistically significant (SOE: low). 3j. … The AUROC ranged from 0.52 to 0.55 (3 studies) (SOE: low).
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
    November 01, 2020 - RCT, estimated slope difference, -0.58; 95% CI, -0.92 to -0.23, favoring bilevel ventilation] (SOE: Low … ventilation and high flow nasal cannula (1 RCT) did not differ for improving breathlessness (SOE: Low … or health-related quality of life, but did improve exercise capacity, more than usual care (SOE: Low … intervention types were more effective for improving breathlessness compared with usual care (SOE: Low … • Anxiolytics were not more effective than placebo for improving breathlessness (SOE: Low).
  3. effectivehealthcare-admin.ahrq.gov/products/asthma-nonpharmacologic-treatment/research-indoor-allergen-reduction
    October 01, 2019 - or health care utilization (low SOE) or improve pulmonary function (low SOE). … component within a broader set of interventions, use of air purification reduced school absenteeism (low … SOE) but did not improve asthma control (low SOE), reduce exacerbations (high SOE), or improve quality … SOE), and reduced school absenteeism (low SOE) but did not reduce emergency department visits (moderate … SOE), hospitalizations (high SOE), or worker absenteeism (low SOE).
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/surveillance-report-3-nonopioid-pharm-chronic-pain.pdf
    July 01, 2022 - ); large effect of cannabis on sedation (SOE: Low)* KQ2. … Efficacy and safety of tanezumab in the treatment of chronic low back pain. … Efficacy and safety of duloxetine in patients with chronic low back pain. … Efficacy and safety of duloxetine in patients with chronic low back pain. … Effect of low-dose amitriptyline on low back pain with a neuropathic component: a post hoc analysis
  5. effectivehealthcare-admin.ahrq.gov/products/binge-eating/clinician
    December 01, 2019 - Low: [evidence low] Low confidence that the evidence reflects the true effect. … [evidence low] No differences were found in BMI or symptoms of depression. … [evidence low] No differences were found in BMI or symptoms of depression. … [evidence low] CBT decreased binge-eating frequency and eating-related psychopathology. … [evidence low] Therapist-led CBT vs.
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-preventive-services-executive-summary.pdf
    June 01, 2022 - of partner, coercive control, self- efficacy, post-traumatic stress disorder, and safety behaviors (lowLow STI rates Supplemental telephone counseling 4-month supply of OCPs, condoms, and in-person … Low Abortion rates Structured telephone support General advice for followup as needed 1 RCT ( … Low Fear, coercive control Interactive online tools Noninteractive online tools 2 RCTs (884) … Low 5 Preventive Service Outcome Intervention Comparison Number of Studies;*
  7. effectivehealthcare-admin.ahrq.gov/products/infertility/research
    March 01, 2022 - For the outcomes of live birth, multiple births, ectopic pregnancy, miscarriage, low birthweight, and … No differences were seen in low birthweight or time to pregnancy (low SOE). … For couples with male factor infertility, live birth rate (moderate SOE) and miscarriage (low SOE) did … ART) included lower live birth rates for African-Americans compared with other racial/ethnic groups (low … after ART, a possible increased risk of neurodevelopmental disorders after ICSI compared with IVF (low
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
    May 01, 2020 - Low (Indirect, imprecise) Table C. … Low (Medium risk of bias, indirect, imprecise) SOE was increased to low given findings from SR which … Low (Imprecise) Table O. … ) or in mode of delivery (low SOE) … Low (one study) Table BB.
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
    December 01, 2015 - weeks (low SOE), and 96 weeks of followup (low SOE). … (low SOE). … John’s wort (low SOE). However, all trials compared St. … John’s wort (low SOE). … SOE), and suicidal ideas or behaviors (low SOE).
  10. effectivehealthcare-admin.ahrq.gov/products/infantile-hemangioma/clinician
    December 01, 2019 - Resolution outcomes were similar between laser types (low SOE). … The estimated clearance of IH in a child could be as low as 88 percent or as high as 99 percent. … Low: [evidence low] Low confidence that the evidence reflects the true effect. … [evidence low] Neodymium- doped yttrium aluminum garnet Scarring 6 1,340 The incidence … of scarring was low (≤5%).
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
    August 01, 2012 - No significant difference for PANSS (low SoE, 20 RCTs). … No difference for ABS (low SoE, 2 RCTs), ACES (low SoE, 2 RCTs), CDS–S (low SoE, 3 RCTs), HAM–A (low … SoE, 2 RCTs), or PANSS (low SoE, 10 RCTs). … No difference for BPRS (low SoE, 13 RCTs) or CGI–I (low SoE, 2 RCTs). … No difference for BPRS (low SoE, 4 RCTs), CGI–I (low SoE, 3 RCTs), or PANSS (low SoE, 6 RCTs).
  12. effectivehealthcare-admin.ahrq.gov/products/fecal-incontinence/clinician
    December 01, 2019 - [evidence low] PFMT-BF plus electrostimulation vs. … [evidence low] Dextranomer tissue-bulking injections vs. sham injections 1 206 Severity … [evidence low] Severity There was no significant difference in improvement in the CCFIS score … [evidence low] Durasphere® tissue-bulking injections vs. … Low: [evidence low] Low confidence that the evidence reflects the true effect.
  13. effectivehealthcare-admin.ahrq.gov/products/insulin-blood-sugar-2010/research
    December 01, 2019 - the effect of CSII and MDI on HbA 1c (moderate strength of evidence [SOE]) or severe hypoglycemia (low … In adults with type 1 diabetes, HbA 1c decreased more with CSII than with MDI (low SOE), but results … There was no difference in severe hypoglycemia (low SOE). … There was no difference in the rate of severe hypoglycemia (low SOE) or quality of life (low SOE). … The evidence for other outcomes was low or insufficient.
  14. effectivehealthcare-admin.ahrq.gov/products/migraine-treatments/research
    January 01, 2023 - Compared with placebo, antiemetics (low SOE), dihydroergotamine (moderate to high SOE), ergotamine plus … Some opioids may be less effective than some antiemetics or dexamethasone (low SOE). … Sparse and low SOE suggested possible effectiveness of dexamethasone, dipyrone, magnesium sulfate, and … SOE), acupuncture (low SOE), chamomile oil (low SOE), external trigeminal nerve stimulation (low SOE … ), and eye movement desensitization re-processing (low SOE).
  15. Appendix F 0 (xls file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/Appendix%20F_0.xlsx
    November 04, 2021 - Unclear Yes Unclear Unclear Unclear Yes Yes Yes Moderate Chaves,2020 Yes Yes Yes Yes Yes Yes Yes Yes Yes Low … Yes Unclear Yes Yes Yes No No Yes Moderate Langford, 2013 Yes Unclear Yes Yes Yes Yes Yes Yes Yes Low … Yes Yes Yes Yes Yes Unclear Yes Yes No Moderate Pini, 2012 Yes Unclear Yes Yes Yes Yes Yes Yes Yes Low … Unclear Yes Yes Yes Unclear Yes Yes Yes Moderate Schimrigk, 2017 Yes Yes Yes Yes Yes Yes Unclear Yes Yes Low … Unclear Yes Yes Yes Yes Yes No Yes No Moderate Toth, 2012 Yes Yes Unclear Yes Yes Yes Yes Yes Yes Low
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
    January 01, 2017 - • Low: Low confidence that the evidence reflects the true effect. … Our confidence in this conclusion is low (low strength of evidence). … Our confidence in this conclusion is low (low strength of evidence). … given the low frequency of PTH 3 RCT (221) Readmissions/ revisits for dehydration Low SOE for low … Our confidence in this estimate is low (low strength of evidence).
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
    May 01, 2017 - • Low: Low confidence that the evidence reflects the true effect. … Our confidence in this conclusion is low (low strength of evidence). … (low strength of evidence). … Our confidence in these conclusions is low (low strength of evidence) (Table B). … Our confidence in these conclusions is low (low strength of evidence) (Table B).
  18. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - Lastly, acarbose decreased low-density lipoproteins, while rosiglitazone increased low-density lipoproteins … Low-density lipoprotein. … Low to very low Using indirect and a few direct comparisons, metformin showed similar effects on TG … Cardiovascular Low to very low It was unclear whether cardiovascular mortality differed when disease … Peripheral vascular Low to very low No evidence existed that showed a difference between oral diabetes
  19. effectivehealthcare-admin.ahrq.gov/products/diabetic-neuropathy/research-2017
    April 01, 2020 - home monitoring of foot skin temperature (moderate SOE), and specific types of surgical interventions (low … inhibitors duloxetine and venlafaxine (moderate SOE), the anticonvulsants pregabalin and oxcarbazepine (low … ) (low SOE), and the injectable neurotoxin botulinum toxin (low SOE) are more effective than placebo … For nonpharmacologic treatments, alpha-lipoic acid is more effective than placebo (low SOE) and spinal … cord stimulation is more effective than usual care for pain (low SOE), but spinal cord stimulation had
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-apps-G1-2.xlsx
    January 01, 2022 - Unclear Yes Unclear Unclear Unclear Yes Yes Yes Moderate Chaves,2020 Yes Yes Yes Yes Yes Yes Yes Yes Yes Low … Yes Unclear Yes Yes Yes No No Yes Moderate Langford, 2013 Yes Unclear Yes Yes Yes Yes Yes Yes Yes Low … Yes Yes Yes Yes Yes Unclear Yes Yes No Moderate Pini, 2012 Yes Unclear Yes Yes Yes Yes Yes Yes Yes Low … Unclear Yes Yes Yes Unclear Yes Yes Yes Moderate Schimrigk, 2017 Yes Yes Yes Yes Yes Yes Unclear Yes Yes Low … Unclear Yes Yes Yes Yes Yes No Yes No Moderate Toth, 2012 Yes Yes Unclear Yes Yes Yes Yes Yes Yes Low

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