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effectivehealthcare.ahrq.gov/sites/default/files/pdf/vitamin-d-calcium_research-protocol.pdf
September 13, 2013 - of
intention-to-treat analyses and crossovers when so designed, as well as important differential loss … to followup between study arms or overall high loss to followup.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults_research-protocol.pdf
December 20, 2011 - refers to myriad services designed to provide assistance over prolonged periods
to compensate for loss … specification, use
of equivalent outcome measures across experimental and control groups, and
differential loss
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effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
January 01, 2013 - Slide 1
Study Design Considerations for Observational Comparative Effectiveness Research
Prepared for:
Agency for Healthcare Research and Quality (AHRQ)
www.ahrq.gov
Study Design Considerations for Observational Comparative Effectiveness Research
This slide set is based on a user guide titled Developing a Protoco…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
July 01, 2014 - suicidal ideation, hepatotoxicity, weight
gain, metabolic syndrome, gastrointestinal
symptoms, and loss … observational studies based on the adequacy of the patient
selection process, whether important differential loss … to
followup or overall high loss to followup occurred, the
adequacy of exposure and event ascertainment … this report, such
as rates of specific adverse effects (e.g., suicidal ideation,
hepatotoxicity, and loss
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-postpartum-screening_research-protocol.pdf
May 01, 2013 - a change from previous functioning; at least one of the symptoms is either 1) depressed mood or 2) loss … day (as indicated by either subjective account or observation made by others)
• Significant weight loss … observable by others, not merely subjective
feelings of restlessness or being slowed down)
• Fatigue or loss … The symptoms are not better accounted for by bereavement, that is, after the loss of a loved one, the
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tech-brief-patient-provider-strategies-protocol-final.pdf
May 18, 2022 - 2021.5
Though disparities are recognized in health and healthcare, healthcare systems are often
at a loss … Though disparities are recognized in health and healthcare, healthcare systems are often at a loss for
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effectivehealthcare.ahrq.gov/products/ptsd-adult-treatment/research-protocol
December 20, 2011 - , or people that arouse recollections of trauma
Failure to recall an important aspect of trauma
Loss … following types of trauma: accident, combat, sexual, criminal assault, natural disaster, torture, burns, loss
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/deliberative-methods-demonstration-executive-131125.pdf
November 01, 2013 - or psychological harm (e.g., anxiety about
outcomes patients can expect), and economic harm (e.g., loss … In
addition, the public perceived outcomes such as death or job loss for individuals in the
local community … For
example, many participants stated that the economic impact and loss of access to care for
the community
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
February 22, 2012 - related to the effect of
radiation on normal lung tissue, including radiation pneumonitis and permanent loss … groups (includes attrition, crossovers, adherence, and
contamination)
○ Important differential loss … to followup or overall high loss to followup
○ Measurements: equal, reliable, and valid (includes
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
June 01, 2012 - Effective
Health Care
Effective Health Care Program
2
imaging findings; duration of loss of consciousness … certain acute interventions such as intubation and by
specific medications; some research suggests that loss … severity7
Criteria Mild Moderate Severe
Structural Imaging Normal Normal or abnormal Normal or abnormal
Loss
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - Research Protocol: Diabetes Medications for Adults With Type 2 Diabetes: An Update Focused on Monotherapy and Add-On Therapy to Metformin
Evidence-based Practice Center Systemat…
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gaps-womens-health-22.pdf
April 01, 2022 - IBR either before or after radiation
therapy probably results in comparable risk of
implant failure/loss … • Acellular dermal matrices (ADM) use probably
increases the risk of implant failure/loss or need
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_executive.pdf
June 01, 2013 - Topiramate increased risk of paresthesia,
upper respiratory tract infection, and weight loss. … pooled analysis
of individual adverse effects demonstrated significant
increase in risk of weight loss … estimated
that for every 1,000 children treated with topiramate,
87 would experience unintended weight loss … discontinuation due to adverse effects with divalproex
sodium, 1,000 mg/day, and increased risk of weight loss
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preoperative-testing_research-protocol.pdf
May 14, 2013 - the report of intention-to-treat analysis, crossovers between interventions,
important differential loss … to followup between the comparative groups or overall high loss to
follow-up, and the validity and
-
effectivehealthcare.ahrq.gov/products/preoperative-testing/research-protocol
May 14, 2013 - the report of intention-to-treat analysis, crossovers between interventions, important differential loss … to followup between the comparative groups or overall high loss to follow-up, and the validity and adequacy
-
effectivehealthcare.ahrq.gov/sites/default/files/outcome-definition-and-measurement-chapter-6.pptx
January 01, 2013 - medical treatments themselves) but may also include measures of indirect costs (costs of disability or loss … performed in patients using a new drug being compared to other treatments for a liver condition); and when loss
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effectivehealthcare.ahrq.gov/products/telehealth-acute-chronic/research-protocol
February 16, 2017 - in-person and telehealth consultations
Key Question 3: Adverse effects or unintended consequences
Loss … Adverse effects or unintended consequences, such as loss of privacy, breech of data security, misdiagnosis
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effectivehealthcare.ahrq.gov/products/cancer-quality-indicator-testing/research
May 19, 2010 - for depression and psychosocial distress, 7/15 for nausea and vomiting, 2/5 for anorexia and weight loss … transfusion with packed red cells should be offered to the patient within 24 hours
Anorexia/Weight loss
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effectivehealthcare.ahrq.gov/products/tympanostomy-tubes/research-protocol
November 18, 2015 - tube function, children with cleft palate also have a high incidence of OME and associated hearing loss … other craniofacial anomalies, primary ciliary dyskinesia
High-risk children: preexisting hearing loss
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effectivehealthcare.ahrq.gov/products/cancer-ovarian-contraceptives/research-protocol
February 15, 2012 - subjects and providers, blinded assessment of the outcome(s), intention-to-treat analysis, differential loss … to followup between the compared groups or overall high loss to followup, and conflicts of interest.