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  1. effectivehealthcare.ahrq.gov/sites/default/files/transcript_deliberativemethodswebinar.pdf
    April 19, 2012 - They may be organized as single events or have a longer duration where deliberations may take place … And in these cases one might want to consider a design that has a longer timeframe.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-nomination_methods.pdf
    November 01, 2012 - Stakeholder input can often be solicited via email, although longer conversations are sometimes required … But allowing a longer timeline for in-depth topic nomination development comes at the expense of extending
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
    March 29, 2011 - Ideally, longer term outcomes would be available, but such studies are exceedingly rare. … Ideally, longer term outcomes would be available, but such studies are exce� Setting  We will consider
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_executive.pdf
    April 01, 2012 - higher dose; this particular study also suggests that the differences may have been related to the longer … Acute and longer- term outcomes in depressed outpatients requiring one or several treatment steps: A
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - • If we found new evidence that rendered the CER conclusion out of date or no longer applicable, … conclusions involve refinement of original estimates or do the potential changes mean some therapies are no longer
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - • If we found new evidence that rendered the CER conclusion out of date or no longer applicable, … conclusions involve refinement of original estimates or do the potential changes mean some therapies are no longer
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
    March 16, 2017 - behavior is limited to acute treatment is not clear After inclusion of a new study this finding is no longer … suggests there may be little difference in effects between different doses of antipsychotics, although longer-term
  8. effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
    March 16, 2017 - behavior is limited to acute treatment is not clear After inclusion of a new study this finding is no longer … suggests there may be little difference in effects between different doses of antipsychotics, although longer-term
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
    September 01, 2014 - reported by other publications of that study, or (b) a publication with lower patient enrollment reported longer … The second important gap concerns the lack of evidence on comparative longer-term outcomes such as how
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_surveillance.pdf
    September 01, 2012 - • If we found new evidence that rendered the CER conclusion out of date or no longer applicable, … conclusions involve refinement of original estimates or do the potential changes mean some therapies are no longer
  11. S131 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
    October 01, 2007 - scenario is likely when newly mar- keted drugs are compared with competitors that have been available longer … The chance of an initiator being a true new user can be increased by requiring longer periods without
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
    November 01, 2012 - Key Questions not only addressed short-term efficacy and safety but also assessed longer term benefits … No RCTs assessed patients with mild or moderate disease, and few lasted longer than 6 months. … • Longer term (>6 months) studies to establish if treatment benefits are sustained over time and to
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
    August 01, 2013 - , and KQ 4 studies, respectively); and concerns about use of older versions of an intervention no longer … Additional studies utilizing prospectively constructed databases with longer term outcomes data that … effectiveness and safety of available stroke prevention therapies, and strategies for determining longer
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
    September 19, 2014 - Introduction Background Chronic pain, often defined as pain lasting longer than 3 months or past the … versus no opioid therapy or nonopioid alternative therapies that evaluated outcomes at 1 year or longerLonger- term studies of patients clearly with chronic pain comparing those who are prescribed long-term
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-protocol.pdf
    December 01, 2011 - Archived – The lead had previously been saved or assigned but is no longer relevant for any of several … Topic is no longer novel or innovative because other topics in its class have reached diffusion in … the health care system, rendering the topic a “me-too” that no longer addresses an unmet need. 5.
  16. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
    March 01, 2012 - form that could replace postprandial insulin injections, but not basal insulin injections, which use longer-acting … as a fixed-dose, subcutaneous injection, administered twice daily, and liraglutide (Victoza®), a longer-acting … As a result, GLP-1 agonists such as exenatide that mimic the function of GLP-1, but have longer half-lives
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
    September 29, 2014 - Many clinicians that manage cancer pain believe that longer term opioid use is associated with tolerance … the authors of the present systematic review themselves defined “chronic opioid use” as 3 months or longer … disability (Franklin et al, Spine 2008; 33: 199-204), along with several other crosssectional studies of longer
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_executive.pdf
    November 01, 2012 - effects of aerobic, aquatic, and strengthening exercises and ultrasound did not differ at shorter versus longer … Electrical stimulation improved pain at short-term followup but significantly worsened pain at longer … In contrast, we observed that diathermy’s benefits for disability increased with longer followups ( … including exercise (aerobic, aquatic, and strengthening) and ultrasound did not differ at shorter versus longer … Electrical stimulation provided short-term pain improvement, but significantly worsened pain at a longer
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening_research.pdf
    June 01, 2013 - PCR), intermediate turnaround time (results available next day to 2 days after testing performed) or longer … ]), intermediate turnaround time (results available next day to 2 days after testing performed) or longerLonger followup post implementation may be required if sustainability of outcome is desired. … sustainability of outcome or delayed outcomes such as MRSA acquisition or infection rates is desired, then longer
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_disposition-comments.pdf
    May 01, 2013 - wrong;in fact it is likely to be a benefit which could be documented with larger sample sizes and longer … Although we agree that the evidence of an association between maternal depression and infant (and longer … which are also associated with adverse developmental outcomes, from depression itself on the risk of longer … expanded the discussion of the implications of false positives and false negatives to include both longer

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