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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
    March 28, 2019 - Accessed Nov 2, 2017) which in turn references a Geriatric Mental Health Foundation site that is no longer … Each of these factors may have influenced their findings We have Re-written the CQ and this no longer … However, since these may (or may not) change in the near future with a planned update, it may no longer … metabolism via via CYP2C19 and CYP2D6, its long half-life (4-6 days with chronic use), and its even longer
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_surveillance.pdf
    May 16, 2013 - • If we found new evidence that rendered the CER conclusion out of date or no longer applicable, … Duration of AF: In conflict with CER findings, 1 study,9 showed a longer duration of AF (> 6 mo) to … HR=0.092, 95% CI: 0.022, 0.3869 HR=1.67, 95% CI: 1.34, 3.05 10 1 Signal (Other) In 1 study,9 longer … No Signal In 1 study,33 longer duration of AF (> 21 days) was shown to be a significant predictor …  and  recurrence  of  AF,  with  hazard   ratios  of  1.03  and  1.08  for  longer
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
    November 01, 2009 - Thirty-one studies followed patients longer than 5 years. … Two studies had mean followup longer than 10 years. … a variety of different cancers) In addition, specific radiotherapy centers or institutes are no longer … papers reported the centers’ experiences with particle beam therapy over a time span of 10 years or longer … Almost all (171/188) reported a mean followup longer than 12 months and 31 reported mean followup longer
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
    June 28, 2013 - This is very important as many clinicians will be interested in longer-term outcomes. … gaps in the evidence specifically targeting subgroups of interest (elderly, women, minorities) and longer … rate control, but that additional studies are needed, especially the evaluation of outcomes over a longer … Page ES-30, lines 17-20: PVI plus CFAE also causes more scarring, as a result of which longer term outcomes … For virtually all of the KQs, additional studies are needed evaluating longer-term outcomes and quality
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_disposition-comments.pdf
    May 04, 2015 - result from persistence of abnormal sucking movements, which are more entrenched when the infant goes longer … discussing Gaps in Research (p 48- 49), you discuss durability of outcomes, and mention the need for longer … The reason for the low SOE is the small number of infants studied, the need for longer term outcomes … So while it is true that longer term numbers are provided, these are non-comparative. … Key informant #3 Executive Summary Page 76 Line 24 & 26 “Speech impediment” is a term no longer
  6. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - Long-term PN can lead to serious side effects such as liver damage, the risk of which increases the longer … No complications occurred requiring intensive care, hospital stays longer than 5 days, surgical or … nutrition (PN) can lead to serious side effects such as liver damage, the risk of which increases the longer … can also be used to increase nutrient absorption; however, somatropin has not been evaluated for longer … , medical advances are now allowing children with conditions that put them at risk of SBS to lead longer
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
    December 16, 2014 - clinical and research issues and addressing the need for an update (publication of PIVOT results, longer-term … Any benefit of early interventino likely to be smaller in absolute terms and require longer to accrue … vs 4 + 3 or the impact of pecent + biopsies > 50% or tertiary grade 5 on the study endpoints where longer … We have noted in the Discussion that for higher risk patients, longer term HT may be needed to detect … One must also consider that differences may be more pronounced with longer follow-up as late toxicities
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
    May 01, 2019 - Surgery may have additional longer-term risks which may affect subsequent fertility (such as scarring … was limited only to the known short-term risks of these procedures, with no evidence on potential longer … Risks of adverse longer term maternal cancer outcomes were generally not increased after adjustment … of “disease” for U.S. patients who given the financial burden of treatment options they may wait longer … The long lag time between exposure to infertility treatment and the potential development of longer
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_disposition-comments.pdf
    June 05, 2013 - updated our analyses to include new studies identified during the review period, so this comment is no longer … BMI range but clear data on bigger folk from the SOS study then it seems misleading to not these longer … While longer metabolic outcomes are needed, most people would be surprised if there were not an advantage … Peer Reviewer 5 Discussion /Conclusion These are OK, but even more emphasis needs to be placed on longer-term
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
    June 07, 2013 - may lead to underestimating the protective effect, since the continuous use assumption results in longer … may lead to underestimating the protective effect, since the continuous use assumption results in longer … significantly reduced in OC users (OR 0.71, 95% CI 0.64-0.79), with greater reductions seen with longer … exclude studies published prior to 2000 in order to (1) minimize the influence of OC formulations no longer
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_disposition-comments.pdf
    October 01, 2012 - Thank you, this redundancy has been corrected (P 57 of final report) “RISK OF BIAS” no longer occurs … “RISK OF BIAS” no longer occurs in the report. … “RISK OF BIAS” no longer occurs in the report 75 3 PDF General comments Page 75: This is done very … coordinated initiatives, across multiple settings and providers and following patient populations over longer
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
    June 01, 2012 - time productivity among participants in the standard program had improved to a level (50 percent) no longer … more improvements because its members had accumulated more total hours of rehabilitation during this longer … Because impairments sustained from TBI may persist for several years, researchers should collect longer-term
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/presentations-future_research.pdf
    April 01, 2012 - issue Maybe: Most direct way to address long- term outcomes; however, resource requirements for longer-term … common comorbidities; allows for adjustment for confounding; sample size and resources needed for longer … potential limitations Yes: Most efficient method for evaluating less common comorbidities over longer
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ear-infection_research-protocol.pdf
    August 07, 2012 - alone or in combination with antibiotics had a positive effect on 2-week disease outcomes but not on longer … management or tympanostomy tubes only; studies of children up to 18 years of age; followup of 6 months or longerLonger term studies looking at outcomes past 3 months and into adolescence or adulthood.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
    January 15, 2016 - Some studies referred to PDL as either short or transitional PDL or a longer pulse, designated as "long … TEP reviewer #5 Introduction 1/25- Recent literature no longer recognizes a plateau phase. … have more prolonged growth (or could say that the proliferative phase may be more prolonged/last longer
  16. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
    October 01, 2011 - harms) Moderate for CV harms vs. nonselective NSAIDs (multiple systematic review and meta-analyses of longer … withdrawals due to adverse events A meta-analysis of 41 randomized trials found no clear association between longer … Large observational studies showed no association between higher dose and longer duration of nonselective
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
    September 01, 2011 - Gold is no longer in routine use for JIA, but neither is Penicillamine, or several of the other DMARDs … As described above, industry funding is no longer specified as a risk to bias. … long as it had a polyarticular course could be included, including patients with systemic JRA who no longer
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol_0.pdf
    July 10, 2023 - Consequently, guidance for longer-term follow-up, surveillance, and management of special populations … N/A Exclude interventions not available in the US (eg, estriol) and obsolete interventions no longer
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicare-eligible-disabled_research.pdf
    June 01, 2011 - concluded that doing so would increase Medicare expen- ditures to an extent not completely offset by longer … how to best direct programs aimed at appropriate use, further research should examine usage over longer
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
    July 01, 2024 - followup for efficacy, tolerability, and safety represents a critical gap needed to guide treatment longer

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