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Total Results: 938 records

Showing results for "longer".

101. Diagnosis and Treatment of Clinical Alzheimer’s-Type Dementia: Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_1.pdf
     April 01, 2020 - In addition, few included trials were longer than 26 weeks, so longer-term drug effects were unclear … excluded from analyses due to high risk of bias, often because of high attrition, especially trials longer … We could not determine the likelihood of longer- term benefits, because no eligible cholinesterase inhibitor … Future BPSD drug trials should be longer to better establish the evidence for long-term efficacy and

102. Hemorrhage-Postpartum Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
     April 01, 2015 - intermediate outcomes, such as blood loss, hospital and intensive care unit (ICU) stay, and anemia, and longer … addressed across studies were appropriate and clinically relevant; however, few studies reported longer … harms, differentiating harms of interventions from sequelae of PPH wherever possible, and studying longer … Adverse events and longer term outcomes associated with procedures and surgical interventions are also … Some studies with longer term followup reported adverse effects on future fertility and menstrual changes

103. Disposition of Comments Report for Recurrent Nephrolithiasis in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_disposition-comments.pdf
     July 26, 2012 - Assimos, Dean Methods On page 6 under the Population(s) section it was stated that the subjects must no longer … We recognize that stating that subjects must no longer have been symptomatic was not clear. … Also, the reviewer is correct in surmising that no studies specifically stated that patients were no longer … full-text in English that enrolled adults age 18 years or older with a history of one or more past (no longer … We also thought that follow-up longer than 1 year might be needed to detect a difference in risk of

104. Ace-Inhibitor-Arb-Update-Surveillance-160328 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
     May 29, 2025 - "" •" If"we"found"new"evidence"that"rendered"the"systematic"review"conclusion"out"of"date"or" no"longer"applicable … degree$of$BP$variability$on$treatment,$reflecting$both$its$effectiveness$in$lowering$BP$levels$and$its$longer … expert$felt$the$original$ review’s$conclusions$were$ current$while$another$felt$ conclusions$may$no$longer … &ACEIs&or&ARBs& Conclusions$may$no$longer$be$ current. … &ARBs& Conclusions$may$no$longer$be$ current.

105. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - Long-term PN can lead to serious side effects such as liver damage, the risk of which increases the longer … No complications occurred requiring intensive care, hospital stays longer than 5 days, surgical or … nutrition (PN) can lead to serious side effects such as liver damage, the risk of which increases the longer … can also be used to increase nutrient absorption; however, somatropin has not been evaluated for longer … , medical advances are now allowing children with conditions that put them at risk of SBS to lead longer

106. Disposition of Comments Report for Comparative Effectiveness Review No. 131 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
     February 25, 2014 - We are no longer including data from these time points. … We are no longer looking at this time point for KQ2. The first time point will be 1 year. … We are no longer looking at response rates. … We have revised our conclusions for KQ1 and no longer specifically mention adalimumab in the text. … However, safety points in this study may have been useful since it has longer term data.

107. Methods Future Research Needs Number 8: Framework for Considering Study Designs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-framework_research.pdf
     March 01, 2012 - As these are prospective studies, duration is longer than retrospective studies. … Because these are prospective studies, duration is longer than retrospective studies. … Crossover may occur, especially in longer duration observation. … However, such studies often take somewhat longer than envisioned. … However, such studies may often take longer than planned.

108. Gout Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
     March 01, 2016 - • Moderate-strength evidence supports the finding that longer courses of prophylaxis with colchicine … over time, despite the fact that this outcome has not been studied in any placebo-controlled trial of longer … timing of the occurrence of acute gout attacks in the weeks following initiation of 13 ULT, that longer … Longer term studies will be needed to assess the degree to which ULT reduces acute gout attacks relative … for acute gout when initiating urate lowering therapy with low-dose colchicine or NSAIDs should be longer

109. Gout Executive-2016 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
     January 01, 2016 - prior gout diagnosis, including the following subgroups: - Male and female patients - Patients with longer … A negative MSU finding was associated with higher risk for undergoing arthroscopic drainage, longer … criteria alone was recently assessed and compared in patients with shorter (2 years or less) and longer … all clinical diagnostic and classification criteria are greater for patients with symptom duration longer … suggested that DECT may be a useful adjunct to clinical algorithms among patients with disease of longer

110. Disposition of Comments_Psychosocial and Pharmacologic Interventions for Disruptive Behavior in Children and Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disposition-comments.pdf
     April 10, 2025 - Academy of Pediatrics 1 Executive Summary In Executive Summary: Clarification is needed for “longer-term … Would be good to comment on any comparison you can do of short- versus longer- term treatment and impact … the Executive Summary under Main Findings, “Evidence for some psychosocial interventions and for longer-term

111. Treatment for Restless Legs Syndrome Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
     November 27, 2012 - moderate-to-severe RLS on a patient’s health and well-being, conducting a placebo-controlled trial longer … continue to believe that adequately assessing the long-term efficacy of these treatments through longer … read “the majority of randomized, controlled trials were of short duration (<12 weeks), however, longer … Further, as stated on ES-17 and pg.49 of the draft report, levodopa is no longer widely used for treatment

112. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pepticulcer_hi_impact.pdf
     January 01, 2012 - 11 – Peptic Ulcer Disease and Dyspepsia such as liver damage, the risk of which increases the longer … nutrition (PN) can lead to serious side effects such as liver damage, the risk of which increases the longer … increase absorption of nutrients; however, somatropin has not been evaluated in patients with SBS for longer … medical advances are now allowing children with conditions that put them at risk for SBS to lead longer

113. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
     June 01, 2010 - condition of interest, may involve intensively administered interventions, and may not adequately examine longer-term … Longer periods without evidence that the patient used the cohort-defining drug probably reduce the potential … for selection bias because longer periods make it unlikely that apparent new users are actually former … atypical antipsychotic medication, which drugs have better persistency and sustained effectiveness for longer-term

114. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
     June 01, 2010 - condition of interest, may involve intensively administered interventions, and may not adequately examine longer-term … Longer periods without evidence that the patient used the cohort-defining drug probably reduce the potential … for selection bias because longer periods make it unlikely that apparent new users are actually former … atypical antipsychotic medication, which drugs have better persistency and sustained effectiveness for longer-term

115. Disposition of Comments Report for Biologic and Nonbiologic Systemic Agents and Phottherapy for Treatment of Chronic Plaque Psoriasis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
     November 27, 2012 - 12 to 16 weeks in patients who fail treatment, there are patients who are on these therapies much longer … Alefacept is no longer available; Astellas pulled the drug from the market in December 2011. … However, to reflect that it is no longer being sold in the US, we have clarified this in our introduction … We have mentioned the fact that longer term followup is needed to accurately capture most adverse

116. Evidence Summary_Pharmacologic and Nonpharmacologic Treatments for PTSD: An Update of the PTSD-Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharma-ptsd-update-summary.pdf
     November 01, 2020 - elements in published studies: less than half of studies reported on the loss of PTSD diagnosis (i.e., no longer

117. Comparative Effectiveness Review No. 241_Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
     October 01, 2021 - The addition of larger, well-conducted randomized controlled trials of longer duration and including

118. Executive Summary_Systematic Review: Use of Telehealth During the COVID-19 Era (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/use-telehealth-during-COVID-19-executive-summary.pdf
     January 01, 2023 - The question is no longer whether to use telehealth but how to provide • Telehealth may improve access

119. Blood-Clots-Hip-Knee-Surgery Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
     March 01, 2012 - thromboprophylaxis method, what are the effects of prolonging thromboprophylaxis for 28 days or 3 longer … Pharmacologic, mechanical, combination of pharmacologic and mechanical, IVC filter, or longer … were defined in most trials as the postoperative period and may imply a more immediate rather than longer … The impact of prolonging prophylaxis for 28 days or longer on events was compared with prophylaxis … Four previous meta-analyses compared the impact of longer versus shorter duration pharmacologic prophylaxis

120. Kidney-Disease-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
     October 01, 2012 - • If we found new evidence that rendered the CER conclusion out of date or no longer applicable, … conclusions involve refinement of original estimates or do the potential changes mean some therapies are no longer … Rosiglitazone- The UK commission on Human medicines concluded that the benefits of rosiglitazone no longer … sensitivity and specificity for CKD as defined by kidney dysfunction or damage lasting 3 months or longer … sensitivity and specificity for CKD as defined by kidney dysfunction or damage lasting 3 months or longer