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Total Results: 1,435 records

Showing results for "long term".

341. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fetal-surgery_disposition-comments.pdf
     July 05, 2011 - Peer Reviewer #4 Results you state: "there are currently no long-term data available to assess maternal … I would disagree, and suggests you go back and read reference #137 which is the only long- term outcomes … Peer Reviewer #7 Results The summary talks a lot about indications, lack ofrandomization, long-term … least validated method; the potential for damage to adjacent structures and the completely unknown long-term … Similarly, does this impact her future long term health – are there more adhesions that may make subsequent

342. Executive Summary_Systematic Review: Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
     March 01, 2025 - Multiple long-term studies have been conducted that provide insight into the role of digestible carbohydrates … term. … A rigorous long-term prospective study in a controlled feeding environment would answer these questions … As studies getting to the outcome of interest are challenging given the long-term nature required, shorter … term studies looking at surrogate markers will continue to be more feasible.

343. Disposition of Comments Report for Treatment of Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
     June 28, 2013 - Most importantly, in the opinion of this reviewer, the report highlights the almost complete lack of long-term … We thank the reviewer for their comments and agree that long-term studies and studies that address … We also highlight in the limitations section of the report how the evidence supporting long-term outcomes … We agree that long-term and quality-of-life outcomes are lacking throughout the available evidence. … If there are not yet hard data supporting the long-term benefit of maintenance of sinus rhythm (in

344. Disposition of Comments for CER 166 Calcineurin Inhibitors (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
     March 15, 2016 - Long-term pragmatic clinical studies and large simple trials might be most informative for comparing … throughout the Results and Discussion to highlight these limitations, and identify the need for long-term … Long-term evaluation of analytical methods used in sirolimus therapeutic drug monitoring. … term outcomes etc.... … term. 8.

345. Interventions Targeting Sensory Challenges in Children With Autism Spectrum Disorders - An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-interventions-disposition.pdf
     May 26, 2017 - General Comments One point that was unclear to me was what time frame the authors considered to be ”long-term … We have clarified the time frame to reflect ≤ 6 months as short term and greater than 6 months as long … term. … Methods The key issues studied (impact on core autism symptoms and behavior problems, risk of harm, long-term … Methods The key issues studied (impact on core autism symptoms and behavior problems, risk of harm, long-term

346. 04-E029-1 Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_executive.pdf
     December 01, 2011 - Both surgical and radiation treatments result in significant short- and long-term adverse events, including … Immediate active treatment has tradeoffs, including the harms of short- and long-term complications from … curative treatments and the benefits of potential reductions in long- term morbidity and mortality. … What are the comparative short- and long-term outcomes of active surveillance versus immediate treatment … Key Question 4 What are the comparative short- and long-term outcomes of active surveillance versus

347. Disposition of Comments Report for CER 132 Combination Therapy Versus Intensification of Statin Monotherapy: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
     September 01, 2014 - We think that it would be over-reaching to make any statements about long-term benefits of ezetimibe … Ezetimibe may be the only alternative that is tolerable in the long term for the majority of people … Overall, we are unable to conclude whether there are any long-term advantages or serious disadvantages … However, what is clinically missing and perhaps the most relevant is the long-term “hard” or clinical … Overall, we are unable to conclude whether there are any long-term advantages or serious disadvantages

348. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - Long-term PN can, however, lead to serious side effects, such as liver damage, the risk of which increases … No effective treatments are available to improve long-term nutritional absorption other than intestinal … Additionally, a long-term extension trial demonstrated that some patients were able to completely stop … as liver damage, the risk of which increases the longer a patient is PN-dependent.4 No effective long-term … wide acceptance among clinicians if the drug continues to show favorable efficacy and acceptable long-term

349. Insulin Delivery and Glucose Monitoring Methods: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar_research.pdf
     August 01, 2015 - While data on long-term microvascular or macrovascular complications would be informative, it would … The resultant hyperglycemia, if untreated, can lead to long-term complications, including microvascular … Long-term clinical outcomes were not specifically included for prioritization by the stakeholders. … While prevention of long-term macrovascular and microvascular complications is the ultimate goal of … While we feel that long-term clinical outcomes, such as mortality, macrovascular complications, and

350. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0075_03-10-2009.pdf
     January 01, 2009 - conjunction with one another, provide the highest rate of disease management with the lowest risk of long-term

351. 1. For children with disruptive behavior disorders (DBDs), including Oppositional Defiant Disorder (ODD), Conduct disorder (CD), and Disruptive Behavior Disorder Not Otherwise Specified (DBD NOS), what is the short-term and long-term… | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/1-for-children-with-disruptive-behavior-disorders-dbds-including-oppositional-defiant-disorder-odd-conduct-disorder-cd-and-disruptive-behavior-disorder-not-otherwise-specified-dbd-nos-what-is-the-short-term-and-long-term-com

352. Whole-Body Vibration Therapy for Osteoporosis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
     January 01, 2020 - However, safety concerns emerged from key informant discussions, including unknown long-term harms … Disadvantages of whole-body vibration therapy include unknown long-term safety and out-of-pocket costs … whether any benefits from whole-body vibration therapy will persist over time, or about potential long-term … Studies that measured compliance found a wide range, raising questions about long-term adherence for … Nor do we know the potential long-term harms from using whole-body vibration therapy.

353. Evidence Summary: Comparative Effectiveness Review No. 245_Breast Reconstruction After Mastectomy: A Systematic Review and Meta-Analysis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-evidence-summary-updated-1.pdf
     October 01, 2021 - o Compared with AR, although results in the short term (1 to 1.3 months) are inconsistent, IBR probably … poses greater risk of reconstructive failure in the long term (1.5 to 4 years) (Moderate SoE). … Reconstructive failure ◆◆ with IBR in the long term . . . . .

354. Evidence Summary: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
     October 01, 2020 - uncertainties about the effectiveness and harms of various treatment options, preventive options for long … - term recurrence, and detection strategies for CRC. … Studies found no evidence of differences in rates of long-term diverticulitis recurrence or elective

355. Making Healthcare Safer IV Rapid Review: Prevention in Adults of Infection With Transmission of Multidrug-Resistant Organisms (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-rapid-research.pdf
     April 01, 2024 - outbreak settings), automated room decontamination or cleaning feedback protocols, and IPC practices in long-term … can improve patient safety across the healthcare system—from hospitals to primary care practices, long-term … Long- Term Impact of Universal Contact Precautions on Rates of Multidrug-Resistant Organisms in ICUs … Approaches to multidrug-resistant organism prevention and control in long-term care facilities for … “studies did not adequately evaluate the long- term effects…” “suggests intervention reduces HAI

356. Crosscutting-Horizon-Scan-High-Impact-1312 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - . 1 Digital Medicines (Proteus Digital Health Feedback System) for Chronic Conditions Requiring Long-term … 1. * Digital medicines (Proteus Digital Health Feedback System) for chronic conditions requiring long-term … ES-3 Digital Medicines (Proteus Digital Health Feedback System) for Chronic Conditions Requiring Long-term … Overall, experts did not anticipate that long-term costs would differ from those of the traditional … Adherence to long-term therapies.

357. Noninvasive, Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
     September 20, 2017 - benefits.6-8 Lack of evidence on long-term effectiveness9 and serious safety concerns10 speak to the … and long term (at least 1 year); we will focus on longer-term (>1 year) effects where possible o … (up to 6 months), intermediate term (6-12 months) and long term (at least 1 year); focus on longer … Trends in long-term opioid therapy for chronic non-cancer pain. … The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a

358. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_june_2012.pdf
     January 01, 2012 - the disease to achieve near-normal glycemia and avoid acute (i.e., hypoglycemia, hyperglycemia) and long-term … However, given the high risks associated with some bariatric surgery procedures and the long-term lifestyle … However, given the high risks associated with some forms of bariatric surgery and the long-term lifestyle … However, multiple experts noted the lack of studies of long-term outcomes for patients with BMI <35 … However, it is possible that the long-term cost of miniosmotic pump insertion and subcutaneous exenatide

359. Gorman_Asynchronous (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/gorman.pdf
     January 01, 2009 - Problem Solving, Negotiating, Decision Making, Standing Up for Your Rights Slide 3: About me • Long …  term survivor of metastatic melanoma, 10+ years • Patient advocate • NCCS 8 years o Personal

360. psychiatric-readmissions-protocols-140904 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/psychiatric-readmissions_research-protocol.pdf
     December 31, 2014 - readmissions includes providing alternatives to psychiatric hospitalization (e.g., day hospital, short-term … ) is efficacious and cost-effective; however, whether such analyses adequately consider short- and long-term … What are other immediate and long-term implications (such as ethical, privacy, equity, or cost considerations … Assertive Community Treatment), partial hospitalization, residential treatment or housing with intensive long … term services and supports.