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Total Results: 1,425 records

Showing results for "long term".

321. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - Long-term PN can lead to serious side effects, such as liver damage, the risk of which increases the … No effective treatments are available to improve long-term nutritional absorption other than intestinal … Additionally, a long-term extension trial demonstrated that some patients were able to completely stop … as liver damage, the risk of which increases the longer a patient is PN-dependent.4 No effective long-term … wide acceptance among clinicians if the drug continues to show favorable efficacy and acceptable long-term

322. Evidence-Summary-CER-206-Sodium-And-Potassium-Intake-Effects-On-Chronic-Disease-Outcomes-And-Risk (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
     June 01, 2018 - enough follow up to assess long term chronic disease outcomes. … • Of the small number of studies that assessed long term CVD outcomes, few assessed these as primary … • Long-term outcomes resulting from brief interventions may not show effects. … RCTs in populations confined to residential settings such as long-term care facilities, schools, or … Study Design • Observational studies predominated for long term chronic disease outcomes.

323. Disposition of Comments for CER 159 Insomnia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
     December 30, 2015 - There has not yet been a study that compares CBT-I to true long-term pharmacotherapy. … We have also recommended longer-term trials to assess long-term adverse effects and harms and that … We sought to assess the longterm efficacy of interventions for insomnia disorder; few long term trials … December 30, 2015 22 Commentator & Affiliation Section Comment Response associated with long-term … term use’ implies that there are side effects with long term use.

324. Disposition of Comments Report for Medication Adherence Interventions: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-adherence-interventions_disposition-comments.pdf
     September 11, 2012 - The issue of long-term outcomes and applicability now receives expanded attention in the report. … This reflects a long-standing debate between those who want to understand each component in isolation … The issue of long-term outcomes and applicability now receives expanded attention in the report. … authors recommend what would define a minimum length of follow-up for research to better characterize “long-term … We added some text explaining our preference for long outcomes at 1 year or greater Peer Reviewer

325. An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_disposition-comments.pdf
     December 01, 2011 - This review does not address evaluations of long-term clinical outcomes reported in noncomparative … This review does not address evaluations of long-term clinical outcomes reported in noncomparative … , studies focusing on long-term costs (>5 years) are more relevant than those focusing on short- term … This review does not address evaluations of long-term clinical outcomes reported in noncomparative … This review does not address evaluations of long-term clinical outcomes reported in noncomparative

326. Disposition of Comments Report for Comparative Effectiveness Review No. 131 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
     February 25, 2014 - used: 2-4 weeks “immediate response”; 8-12 weeks “induction”; 15-19 weeks “4 months”; 18-24 weeks “long-term … Peer Reviewer-1 Discussion/ conclusion How are we ever going to do long term, large studies without … Public: UCB Results, KQ3 For the evaluation of long-term remission, it is difficult to consent patients … to long-term randomized clinical trials resulting in randomization of patients to placebo, with the … Specifically regarding CIMZIA, the report would be improved by including the following two long-term

327. Traumatic-Brain-Injury-Rehabilitation Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation_research-protocol.pdf
     October 25, 2010 - sources. 5-7 More than 40 percent of people hospitalized with nonfatal TBIs develop associated long-term … depression, mood swings, impulsiveness, agitation, and social isolation. 8 The incidence of TBI-related long-term … affected domains are lessened, rehabilitation may continue via specialized services such as those for long-term … psychosocial disorders. 11 Postacute rehabilitation settings include long-term rehabilitation facilities … ―traumatic brain injur$‖. ti, ab ―head injur$‖, ti, ab Post acute.tw Postacute.tw Chronic.tw Long-term.tw

328. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
     March 29, 2011 - brain.16,17 Despite potential benefits, there is uncertainty about the efficacy and safety of the long-term … the treatment of PKU under the stipulation that studies continue regarding the drug’s efficacy and long-term … The long-term effects of sapropterin dihydrochloride have not been studied.5,20-21 The role of sapropterin … As of 2009, there were thirteen clinical trials yielding promising results of this drug, but long- term … Existing literature cites few RCTs that predict with certainty the long-term effects of pharmacological

329. Disposition of Comments: Technical Brief No. 39_Disparities and Barriers to Pediatric Cancer Survivorship Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-39-pediatric-cancer-survivorship-comments.pdf
     March 01, 2021 - Background After completion of treatment, childhood cancer survivors (CCS) face many challenges regarding long-term … Medical Care in Long-Term Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor … behavioral factors that are preventing childhood cancer survivors from fully recovering from the long-term … I hope this brief will bring more research and advocacy to long term care for CCS's. … term health outcomes.

330. Horizon Scanning_Rapid Cost Analyses of Selected Potential High-Impact Intervention Reports (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
     January 01, 2015 - Again, we did not attempt to calculate long-term costs and effectiveness. … Data on the cost and health impact of long-term use of the technology are not yet available. … Lorcaserin competes with at least 3 other long-term prescription weight-loss drugs (i.e., orlistat, … Most estimates are based on data describing patients requiring long-term home parenteral nutrition ( … However, long-term results are still being evaluated.

331. Prostate-Cancer-Test Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_executive.pdf
     April 01, 2013 - decisionmaking about prognosis and triage for active surveillance and/or aggressive treatment), and long-term … study comparators; and (5) intermediate (diagnostic accuracy, impact on decisionmaking, harms) and long-term … comparators (Table A), and all other intermediate (impact on decisionmaking, harms of biopsy) and long … likely that more time will be needed for studies to assess the diagnostic accuracy of predicting long-term … accuracy than tPSA elevations, but insufficient evidence that this led to improved intermediate or long-term

332. Disposition of Comments for Treatment Strategies for Patients With Peripheral Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_disposition-comments.pdf
     May 29, 2013 - The long-term results from the BASIL study were included in the report in KQ 3 starting with Table 23 … The value of this endpoint is unclear since no data is presented as to the mid and long term impact … For example, the mid and long term results of the BASIL trial indicate a significant benefit of surgical … TEP Member 1 Results too long Noted. … One of the key clinical findings from the BASIL long- term study (Bradbury A et al J Vasc Surg 2010)

333. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-knee-update-disposition-archived.pdf
     May 04, 2017 - We have added the definitions of short-term, medium-term, and long-term to the abstract. … Outcome measures were stratified to short-, medium- and long - term effects. such stratification is … Few clinicians expect long- term effects in chronic pain patients with TENS. … When the results speak of long term effects is this with an application of continual application of … measure long term outcomes).

334. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-disposition.pdf
     May 04, 2017 - We have added the definitions of short-term, medium-term, and long-term to the abstract. … Outcome measures were stratified to short-, medium- and long - term effects. such stratification is … Few clinicians expect long- term effects in chronic pain patients with TENS. … When the results speak of long term effects is this with an application of continual application of … measure long term outcomes).

335. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
     April 01, 2011 - Key Questions Key questions were: KQ1: Among children ages 2-12 with ASDs, what are the short- and long-term … Few studies provided data on long-term outcomes after cessation of treatment. … Long-term outcome of social skills intervention based on interactive LEGO© Play. … Acute and long- term safety and tolerability of risperidone in children with autism. … Effects of short- and long-term risperidone treatment on prolactin levels in children with autism.

336. Medication-Therapy-Management Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
     January 01, 2014 - settings (e.g., outpatient clinics, physician practices), retail pharmacies in the community, and in long-term … MTM services will help patients and their health care providers achieve important intermediate and long-term … within their plan by selecting one or more of the following provider types: • Local pharmacist • Long-term … must have been seen in ambulatory settings (e.g., outpatient clinics or private physician offices, long-term … Ambulatory (e.g., outpatient clinics, private physician offices, or retail pharmacy settings) and long-term

337. Insomnia Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_executive.pdf
     December 01, 2015 - physical pain and discomfort, and cognitive deficiencies.3 Insomnia may also be associated with long-term … Data from large long-term observational studies are included to further assess pharmacologic harms. … What are the long-term harms of treatments for insomnia disorder in adults? … Sleep outcomes remain improved long term (low-strength evidence). … All improvements in sleep outcomes were maintained long term.

338. Disposition of Comments for CER 195 Management of Uterine Fibroids (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-195-disposition-comments-uterine-fibroids.pdf
     December 14, 2017 - and long term intermittent use of Ulipristal in the medical management of uterine fibroids and emerging … treatment related endpoints and no adjunctive surgery related endpoints, and they, combined with long-term … We have included the Donnez et al 2016 publication "Long term management of uterine fibroids with ulipristal … Uterine artery embolization versus laparoscopic occlusion of uterine arteries for leiomyomas: long-term … The probability of major complications was high in two studies that reported long-term follow-up (21%

339. Interventions Targeting Sensory Challenges in Children With Autism Spectrum Disorders - An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-interventions-disposition.pdf
     May 26, 2017 - General Comments One point that was unclear to me was what time frame the authors considered to be ”long-term … We have clarified the time frame to reflect ≤ 6 months as short term and greater than 6 months as long … term. … Methods The key issues studied (impact on core autism symptoms and behavior problems, risk of harm, long-term … Methods The key issues studied (impact on core autism symptoms and behavior problems, risk of harm, long-term

340. Disposition of Comments Report for CER 132 Combination Therapy Versus Intensification of Statin Monotherapy: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
     September 01, 2014 - We think that it would be over-reaching to make any statements about long-term benefits of ezetimibe … Ezetimibe may be the only alternative that is tolerable in the long term for the majority of people … Overall, we are unable to conclude whether there are any long-term advantages or serious disadvantages … However, what is clinically missing and perhaps the most relevant is the long-term “hard” or clinical … Overall, we are unable to conclude whether there are any long-term advantages or serious disadvantages